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Search results 301 to 375 out of 375 for Aprt

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Type Details Score
Publication
1451655 | J:2389
First Author: Moore TF
Year: 1992
Journal: Development
Title: Imprinting of phosphoribosyltransferases during preimplantation development of the mouse mutant, Hprtb-m3.
Volume: 115
Issue: 4
Pages: 1011-6
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Strain
MGI:3606587 | STOCK Aprt<tm1Jat> Tg(pUR288)1Vij/Mmmh
Attribute String: mutant stock, targeted mutation, transgenic
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HT Experiment
E-GEOD-18160 | Kidney Stone Induces Developmental Stage-specific Alterations in Gene Expression
Series Id: GSE18160
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
6402815 | J:135139
First Author: Taggart RT
Year: 1983
Journal: Science
Title: Stable antibody-producing murine hybridomas.
Volume: 219
Issue: 4589
Pages: 1228-30
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Genotype
Genotype
Symbol: Aprt/Aprt Spp1/Spp1
Background: involves: 129S2/SvPas * 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
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Publication
8064675 | J:297526
First Author: Alexiou M
Year: 1994
Journal: J Reprod Fertil
Title: Enzymes of purine salvage and catabolism in the mouse preimplantation embryo measured by high performance liquid chromatography.
Volume: 101
Issue: 1
Pages: 151-8
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Allele
Hprt1<b-m3> | MGI:1857299
 
Name: hypoxanthine phosphoribosyltransferase 1; hypoxanthine guanine phosphoribosyl transferase B, mutation 3
Allele Type: Spontaneous
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Publication
2835663 | J:30949
First Author: Weber CA
Year: 1988
Journal: Mol Cell Biol
Title: Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells.
Volume: 8
Issue: 3
Pages: 1137-46
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Publication
1293155 | J:11865
First Author: Tatsumi K
Year: 1992
Journal: J Dermatol
Title: Molecular bases for hereditary cancer-prone diseases.
Volume: 19
Issue: 11
Pages: 684-9
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Publication
10393170 | J:56281
First Author: Phillips CL
Year: 1999
Journal: EMBO J
Title: Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
Volume: 18
Issue: 13
Pages: 3533-45
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Publication
10428512 | J:56431
First Author: Bolante-Cervantes R
Year: 1999
Journal: Exp Hematol
Title: Pattern of localization of primitive hematopoietic cells in vivo using a novel mouse model.
Volume: 27
Issue: 8
Pages: 1346-52
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Publication
15533837 | J:94446
First Author: Shin-Darlak CY
Year: 2005
Journal: DNA Repair (Amst)
Title: A role for Pms2 in the prevention of tandem CC --> TT substitutions induced by ultraviolet radiation and oxidative stress.
Volume: 4
Issue: 1
Pages: 51-7
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Strain
MGI:5529809 | B6N.Cg-A<w-J> Hprt1<b-m3>
Attribute String: congenic, mutant strain, spontaneous mutation, deletion
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Strain
MGI:5657789 | (B6.Cg-A<w-J> Hprt1<b-m3>/Ems x 129S-Gt(ROSA)26Sor<tm1Sor>/J)F1
Attribute String: F1 hybrid
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Strain
MGI:3625515 | B6.129P2-Hprt1<b-m3>
Attribute String: spontaneous mutation, mutant strain, congenic
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Publication
31118497 | J:302829
First Author: Lu J
Year: 2019
Journal: Nat Rev Rheumatol
Title: Mouse models for human hyperuricaemia: a critical review.
Volume: 15
Issue: 7
Pages: 413-426
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Strain
MGI:4441511 | NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl> Hprt1<b-m3>/EshJ
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
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Publication
8027435 | J:17783
First Author: Heckroth JA
Year: 1994
Journal: J Comp Neurol
Title: A quantitative morphological analysis of the cerebellar nuclei in normal and lurcher mutant mice. II. Volumetric changes in cytological components.
Volume: 343
Issue: 1
Pages: 183-92
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Publication
3029599 | J:15485
First Author: Kuehn MR
Year: 1987
Journal: Nature
Title: A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice.
Volume: 326
Issue: 6110
Pages: 295-8
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Publication
9886073 | J:51651
First Author: Jinnah HA
Year: 1999
Journal: J Neurochem
Title: Influence of age and strain on striatal dopamine loss in a genetic mouse model of Lesch-Nyhan disease.
Volume: 72
Issue: 1
Pages: 225-9
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Publication
1432691 | J:17905
First Author: Jinnah HA
Year: 1992
Journal: J Pharmacol Exp Ther
Title: Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome.
Volume: 263
Issue: 2
Pages: 596-607
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Publication
1528024 | J:3354
First Author: Williamson DJ
Year: 1992
Journal: J Inherit Metab Dis
Title: Mouse models of hypoxanthine phosphoribosyltransferase deficiency.
Volume: 15
Issue: 4
Pages: 665-73
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Publication
23804752 | J:202270
First Author: Guibinga GH
Year: 2013
Journal: Hum Mol Genet
Title: Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome.
Volume: 22
Issue: 22
Pages: 4502-15
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Publication
2292045 | J:2057
First Author: Jinnah HA
Year: 1990
Journal: Brain Res Bull
Title: Animal models of Lesch-Nyhan syndrome.
Volume: 25
Issue: 3
Pages: 467-75
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Strain
MGI:5575501 | (129-Hprt1<b-m3> x C57BL/6)F1
Attribute String: F1 hybrid
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Strain
MGI:3706233 | 129P2/OlaHsd-Hprt1<b-m3>
Attribute String: coisogenic, mutant strain, spontaneous mutation
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Strain
MGI:2162563 | B6.129P2-Hprt1<b-m3>/J
Attribute String: congenic, mutant strain, spontaneous mutation
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Strain
MGI:5654707 | C57BL/6J-Hprt1<b-m3>
Attribute String: mutant strain, spontaneous mutation, congenic
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Strain
MGI:5656446 | (B6.129P2-Hprt1<b-m3>/J x 129S-Gt(ROSA)26Sor<tm1Sor>/J)F1
Attribute String: F1 hybrid, spontaneous mutation, targeted mutation
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Publication
3821905 | J:15483
First Author: Hooper M
Year: 1987
Journal: Nature
Title: HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells.
Volume: 326
Issue: 6110
Pages: 292-5
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Publication
9205113 | J:41459
First Author: Tsuda H
Year: 1997
Journal: Genomics
Title: Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.
Volume: 42
Issue: 3
Pages: 413-21
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Publication
17374562 | J:134847
First Author: Egami K
Year: 2007
Journal: Neurobiol Dis
Title: Basal ganglia dopamine loss due to defect in purine recycling.
Volume: 26
Issue: 2
Pages: 396-407
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Publication
24804781 | J:216086
First Author: Guibinga GH
Year: 2014
Journal: PLoS One
Title: Striatal neurodevelopment is dysregulated in purine metabolism deficiency and impacts DARPP-32, BDNF/TrkB expression and signaling: new insights on the molecular and cellular basis of Lesch-Nyhan Syndrome.
Volume: 9
Issue: 5
Pages: e96575
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Publication
21818316 | J:175856
First Author: Keebaugh AC
Year: 2011
Journal: PLoS One
Title: PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse.
Volume: 6
Issue: 7
Pages: e22381
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Publication
12944494 | J:85443
First Author: Gu JJ
Year: 2003
Journal: Mol Cell Biol
Title: Targeted disruption of the inosine 5'-monophosphate dehydrogenase type I gene in mice.
Volume: 23
Issue: 18
Pages: 6702-12
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Publication
10953035 | J:86045
First Author: Gu JJ
Year: 2000
Journal: J Clin Invest
Title: Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene.
Volume: 106
Issue: 4
Pages: 599-606
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Publication
2912572 | J:161048
First Author: Thompson S
Year: 1989
Journal: Cell
Title: Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells.
Volume: 56
Issue: 2
Pages: 313-21
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Publication
11882343 | J:75479
First Author: Visser JE
Year: 2002
Journal: Brain Res Dev Brain Res
Title: Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Volume: 133
Issue: 2
Pages: 127-39
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Publication
11297820 | J:107966
First Author: Boer P
Year: 2001
Journal: Neurosci Lett
Title: Decelerated rate of dendrite outgrowth from dopaminergic neurons in primary cultures from brains of hypoxanthine phosphoribosyltransferase-deficient knockout mice.
Volume: 303
Issue: 1
Pages: 45-8
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Publication
29401310 | J:259195
First Author: Peeters SB
Year: 2018
Journal: Hum Mol Genet
Title: Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse.
Volume: 27
Issue: 7
Pages: 1252-1262
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Publication
26453761 | J:228653
 
First Author: Tschirner SK
Year: 2015
Journal: Neurosci Lett
Title: Altered histamine neurotransmission in HPRT-deficient mice.
Volume: 609
Pages: 74-80
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Publication
9413985 | J:44728
First Author: Ordway JM
Year: 1997
Journal: Cell
Title: Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.
Volume: 91
Issue: 6
Pages: 753-63
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Publication
22001673 | J:191414
First Author: Hacke K
Year: 2012
Journal: Exp Hematol
Title: Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow.
Volume: 40
Issue: 1
Pages: 3-13.e3
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Publication
29305058 | J:271791
 
First Author: Zizzo MG
Year: 2018
Journal: Auton Neurosci
Title: Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.
Volume: 210
Pages: 55-64
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Publication
35660973 | J:326670
First Author: Witteveen JS
Year: 2022
Journal: Cell Mol Life Sci
Title: HGprt deficiency disrupts dopaminergic circuit development in a genetic mouse model of Lesch-Nyhan disease.
Volume: 79
Issue: 6
Pages: 341
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Publication
7509865 | J:17798
First Author: Jinnah HA
Year: 1994
Journal: J Neurosci
Title: Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Volume: 14
Issue: 3 Pt 1
Pages: 1164-75
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Publication
15908225 | J:102545
First Author: Mikolaenko I
Year: 2005
Journal: Neurobiol Dis
Title: A Golgi study of neuronal architecture in a genetic mouse model for Lesch-Nyhan disease.
Volume: 20
Issue: 2
Pages: 479-90
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Publication
1777100 | J:1847
First Author: Jinnah HA
Year: 1991
Journal: Behav Neurosci
Title: Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome.
Volume: 105
Issue: 6
Pages: 1004-12
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Publication
23340293 | J:202087
First Author: Kamiyama H
Year: 2013
Journal: Clin Cancer Res
Title: Personalized chemotherapy profiling using cancer cell lines from selectable mice.
Volume: 19
Issue: 5
Pages: 1139-46
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Publication
28282408 | J:246011
First Author: Zennaro C
Year: 2017
Journal: PLoS One
Title: The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Volume: 12
Issue: 3
Pages: e0173512
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Publication
28204548 | J:249960
First Author: Varghese S
Year: 2017
Journal: Nucleic Acids Res
Title: In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis.
Volume: 45
Issue: 4
Pages: 2029-2039
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Publication
19912847 | J:2058
First Author: Jinnah HA
Year: 1992
Journal: Mol Cell Neurosci
Title: Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization.
Volume: 3
Issue: 1
Pages: 64-78
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Publication
23584856 | J:198465
First Author: Wattanachanya L
Year: 2013
Journal: Endocrinology
Title: Increased bone mass in mice lacking the adipokine apelin.
Volume: 154
Issue: 6
Pages: 2069-80
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Publication
8492116 | J:11842
First Author: Jinnah HA
Year: 1993
Journal: J Neurochem
Title: Brain purines in a genetic mouse model of Lesch-Nyhan disease.
Volume: 60
Issue: 6
Pages: 2036-45
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Publication
10037486 | J:53129
First Author: Pelled D
Year: 1999
Journal: J Neurochem
Title: Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from hypoxanthine-guanine phosphoribosyltransferase-deficient transgenic mice.
Volume: 72
Issue: 3
Pages: 1139-45
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Genotype
Genotype
Symbol: Hprt1/? Impdh1/Impdh1
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/? Impdh2/Impdh2<+>
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: B6.129P2-Hprt1
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: involves: 129P2/OlaHsd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: B6.129P2-Hprt1
Zygosity: hm
Has Mutant Allele: true
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Publication
3025640 | J:8539
First Author: Dush MK
Year: 1986
Journal: Mol Cell Biol
Title: An unusual adenine phosphoribosyltransferase pseudogene is syntenic with its functional gene and is flanked by highly polymorphic DNAs.
Volume: 6
Issue: 12
Pages: 4161-7
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Publication
9023989 | J:38349
 
First Author: Fieldhouse D
Year: 1997
Journal: Heredity (Edinb)
Title: Substitution rate variation in closely related rodent species.
Volume: 78 ( Pt 1)
Pages: 21-31
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Strain
MGI:2165101 | STOCK Dnmt1<tm3Jae> Hprt1<b-m3> Tg(pPWL512hyg)1Ems/J
Attribute String: mutant stock, transgenic, targeted mutation, spontaneous mutation
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Publication
34813726 | J:340231
First Author: Markaki Y
Year: 2021
Journal: Cell
Title: Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Volume: 184
Issue: 25
Pages: 6174-6192.e32
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Publication
7739908 | J:92459
First Author: Johnson KA
Year: 1995
Journal: Nucleic Acids Res
Title: Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections.
Volume: 23
Issue: 7
Pages: 1273-5
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Publication
16887963 | J:138376
First Author: Hsiao FC
Year: 2006
Journal: J Immunol
Title: Cutting edge: Epstein-Barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells.
Volume: 177
Issue: 4
Pages: 2056-60
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Publication
28919262 | J:279991
First Author: Lin J
Year: 2017
Journal: Stem Cell Reports
Title: PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines.
Volume: 9
Issue: 4
Pages: 1062-1070
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Publication
9278500 | J:92995
First Author: Tucker KL
Year: 1997
Journal: Nucleic Acids Res
Title: A transgenic mouse strain expressing four drug-selectable marker genes.
Volume: 25
Issue: 18
Pages: 3745-6
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Publication
36417913 | J:340911
First Author: Janas JA
Year: 2022
Journal: Mol Cell
Title: Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation.
Volume: 82
Issue: 24
Pages: 4627-4646.e14
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Genotype
Genotype
Symbol: Dnmt1/Dnmt1 Hprt1/Hprt1 Tg(pPWL512hyg)1Ems/Tg(pPWL512hyg)1Ems
Background: STOCK Dnmt1 Hprt1 Tg(pPWL512hyg)1Ems/J
Zygosity: cx
Has Mutant Allele: true
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Publication
27991575 | J:237335
 
First Author: Lin J
Year: 2016
Journal: Sci Rep
Title: Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos.
Volume: 6
Pages: 39457
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Publication
31001916 | J:276929
First Author: Zhou H
Year: 2019
Journal: Genesis
Title: The testicular soma of Tsc22d3 knockout mice supports spermatogenesis and germline transmission from spermatogonial stem cell lines upon transplantation.
Volume: 57
Issue: 6
Pages: e23295
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Publication
- | J:3478
First Author: Moore TF
Year: 1992
Journal: Mouse Genome
Title: Failure to detect age-related reactivation at the Hprt locus
Volume: 90
Issue: 4
Pages: 687-89
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Publication
18950699 | J:144244
First Author: Yang GS
Year: 2009
Journal: Genomics
Title: Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus.
Volume: 93
Issue: 3
Pages: 196-204
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