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Search results 301 to 400 out of 410 for Astn2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4462465
Assay Type: RNA in situ
Annotation Date: 2010-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462478
Age: postnatal day 6
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4462465
Assay Type: RNA in situ
Annotation Date: 2010-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462478
Age: postnatal day 10
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4462465
Assay Type: RNA in situ
Annotation Date: 2010-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462478
Age: postnatal adult
Image: 2H
Specimen Label: 2H
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884745
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944746
Age: postnatal day 7
Image: g00164 P7
Specimen Label: g00164 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884745
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944746
Age: postnatal day 42
Image: g00164 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00164 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884745
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944746
Age: embryonic day 15.5
Image: g00164 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00164 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_10
Specimen Label: euxassay_012805_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_11
Specimen Label: euxassay_012805_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_14
Specimen Label: euxassay_012805_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_07
Specimen Label: euxassay_012805_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_08
Specimen Label: euxassay_012805_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_17
Specimen Label: euxassay_012805_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_18
Specimen Label: euxassay_012805_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_07
Specimen Label: euxassay_012805_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_08
Specimen Label: euxassay_012805_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_09
Specimen Label: euxassay_012805_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_10
Specimen Label: euxassay_012805_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_11
Specimen Label: euxassay_012805_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_12
Specimen Label: euxassay_012805_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_13
Specimen Label: euxassay_012805_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_14
Specimen Label: euxassay_012805_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_15
Specimen Label: euxassay_012805_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_16
Specimen Label: euxassay_012805_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_17
Specimen Label: euxassay_012805_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_18
Specimen Label: euxassay_012805_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1617723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_07
Specimen Label: euxassay_012805_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1617723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_08
Specimen Label: euxassay_012805_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1617723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_09
Specimen Label: euxassay_012805_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1617723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_19
Specimen Label: euxassay_012805_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1617723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_20
Specimen Label: euxassay_012805_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884745
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4944746
Age: embryonic day 15.5
Image: g00164 E15.5
Specimen Label: g00164 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4884745
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944746
Age: postnatal day 7
Image: g00164 P7
Specimen Label: g00164 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884745
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944746
Age: postnatal day 42
Image: g00164 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00164 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_08
Specimen Label: euxassay_012805_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_09
Specimen Label: euxassay_012805_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_10
Specimen Label: euxassay_012805_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_11
Specimen Label: euxassay_012805_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_12
Specimen Label: euxassay_012805_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_13
Specimen Label: euxassay_012805_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_14
Specimen Label: euxassay_012805_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_15
Specimen Label: euxassay_012805_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_16
Specimen Label: euxassay_012805_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_17
Specimen Label: euxassay_012805_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425053
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823283
Age: embryonic day 14.5
Image: euxassay_012805_18
Specimen Label: euxassay_012805_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4462465
Assay Type: RNA in situ
Annotation Date: 2010-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462704
Age: postnatal day 7
Image: S1 coronal
Specimen Label: S1 coronal
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4462465
Assay Type: RNA in situ
Annotation Date: 2010-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462704
Age: postnatal day 7
Image: S1 sagittal
Specimen Label: S1 sagittal
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
- | J:64431
   
First Author: Tomoda T
Year: 1999
Journal: GenBank Submission
Title: Mus musculus astrotactin2 (Astn2) mRNA, complete cds
Pages: AF116573
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Publication
9989976 | J:53343
First Author: Qureshi ST
Year: 1999
Journal: J Exp Med
Title: Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
Volume: 189
Issue: 4
Pages: 615-25
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Publication
38405978 | J:361061
     
First Author: Hanzel M
Year: 2024
Journal: bioRxiv
Title: Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties.
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Publication
27452274 | J:258293
 
First Author: Divya TS
Year: 2016
Journal: Sci Rep
Title: Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development.
Volume: 6
Pages: 30337
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Publication
20005822 | J:157468
First Author: Zagoraiou L
Year: 2009
Journal: Neuron
Title: A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.
Volume: 64
Issue: 5
Pages: 645-62
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Publication
36476860 | J:332216
First Author: Govek KW
Year: 2022
Journal: Cell Rep
Title: Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation.
Volume: 41
Issue: 10
Pages: 111768
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Publication
32170006 | J:286635
First Author: Chen SY
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Parcellation of the striatal complex into dorsal and ventral districts.
Volume: 117
Issue: 13
Pages: 7418-7429
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Publication
21491433 | J:174459
First Author: Boyle MP
Year: 2011
Journal: J Comp Neurol
Title: Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
Volume: 519
Issue: 11
Pages: 2061-89
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Publication
28558017 | J:245526
First Author: Bibollet-Bahena O
Year: 2017
Journal: PLoS One
Title: A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.
Volume: 12
Issue: 5
Pages: e0177977
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30242134 | J:266179
First Author: Behesti H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.
Volume: 115
Issue: 41
Pages: E9717-E9726
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HT Experiment
GSE254224 | Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Astn2<em1Hatn> | MGI:7786603
Name: astrotactin 2; endonuclease-mediated mutation 1, Mary E Hatten
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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Allele
Astn2<em2Hatn> | MGI:7786605
Name: astrotactin 2; endonuclease-mediated mutation 2, Mary E Hatten
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Gt(ROSA)26Sor<tm1.1(CAG-ASTN2/PAPPA)Cya> | MGI:6863916
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:7786606 | STOCK Astn2<em2Hatn>/J
Attribute String: endonuclease-mediated mutation, mutant stock
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Genotype
Genotype
Symbol: Astn2/Astn2
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:7786604 | C57BL/6J-Astn2<em1Hatn>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein
A0A0A6YWJ9
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Publication
1821847 | J:192652
First Author: Fishell G
Year: 1991
Journal: Development
Title: Astrotactin provides a receptor system for CNS neuronal migration.
Volume: 113
Issue: 3
Pages: 755-65
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Protein Domain
IPR026995 | Astrotactin
Type: Family
Description: Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
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Protein Domain
IPR045575 | ASTN_1_2_N
Type: Domain
Description: This entry represents the N-terminal domain of ASTN1/2. This domain includes the transmembrane and cytosolic regions [].Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
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Protein
A0A0A6YWD1
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein Domain
IPR045574 | ASTN1_2_EGF_Fn
Type: Domain
Description: This domain localises to the middle of the C-terminal region of ASTN1 and 2, which comprises a EGF- like domain (EGF4) and a fibronectin type III (Fn(III)) domain []. These subdomains are located between the MACPF and annexin-like domains. The structure of Fn(III) from ASTN2 revealed an unexpected feature which has two additional beta strands folded across the core. The junction between EGF-4 and Fn(III) domains in ASTN2 (but not in ASTN1) is thought to be an inositol triphosphate binding site [].Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
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Publication
27249642 | -
 
First Author: Ni T
Year: 2016
Journal: Open Biol
Title: Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Volume: 6
Issue: 5
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Publication
35053393 | J:318677
 
First Author: Luo Y
Year: 2022
Journal: Cells
Title: Generation and Application of Inducible Chimeric RNA ASTN2-PAPPAas Knockin Mouse Model.
Volume: 11
Issue: 2
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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