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Search results 301 to 400 out of 410 for Bach2

0.034s
Type Details Score
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3507815
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:5612
Specimen Label: GUDMAP:5612
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12590
Specimen Label: GUDMAP:12590
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12591
Specimen Label: GUDMAP:12591
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:13617
Specimen Label: GUDMAP:13617
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12591
Specimen Label: GUDMAP:12591
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3507815
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3507815
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2776423
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:13617
Specimen Label: GUDMAP:13617
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:5612
Specimen Label: GUDMAP:5612
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12590
Specimen Label: GUDMAP:12590
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12591
Specimen Label: GUDMAP:12591
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:13617
Specimen Label: GUDMAP:13617
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2860123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12249
Specimen Label: GUDMAP:12249
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:12591
Specimen Label: GUDMAP:12591
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772123
Stage: TS23
Assay Id: MGI:5539311
Age: embryonic day 15.5
Image: GUDMAP:13617
Specimen Label: GUDMAP:13617
Detected: false
Specimen Num: 5
GXD Expression  
Probe: MGI:3506292
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3817723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513160
Age: embryonic day 15.5
Note: Both sexes were examined; no reproducible differences were detected between them.
Specimen Label: Table 3
Detected: true
Specimen Num: 2
Publication
First Author: Ito N
Year: 2009
Journal: Genes Cells
Title: Crystal structure of the Bach1 BTB domain and its regulation of homodimerization.
Volume: 14
Issue: 2
Pages: 167-78
Publication
First Author: Russ BE
Year: 2023
Journal: Cell Rep
Title: Active maintenance of CD8(+) T cell naivety through regulation of global genome architecture.
Volume: 42
Issue: 10
Pages: 113301
Publication
First Author: Kurotaki D
Year: 2018
Journal: Cell Rep
Title: Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors.
Volume: 22
Issue: 10
Pages: 2628-2641
UniProt Feature
Begin: 1
Description: Transcription regulator protein BACH2
Type: chain
End: 839
Publication
First Author: Katsuoka F
Year: 2003
Journal: Mol Cell Biol
Title: Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response.
Volume: 23
Issue: 4
Pages: 1163-74
Protein
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: false
Publication    
First Author: Khor B
Year: 2015
Journal: Elife
Title: The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
Volume: 4
Publication
First Author: Gu Y
Year: 2022
Journal: Cell Rep
Title: Multi-omics profiling visualizes dynamics of cardiac development and functions.
Volume: 41
Issue: 13
Pages: 111891
Publication    
First Author: Feng J
Year: 2022
Journal: Elife
Title: TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.
Volume: 11
Publication
First Author: van der Weyden L
Year: 2020
Journal: G3 (Bethesda)
Title: A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.
Volume: 10
Issue: 6
Pages: 1869-1877
Publication
First Author: Foronda M
Year: 2014
Journal: Cell Rep
Title: Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation.
Volume: 8
Issue: 2
Pages: 487-500
Publication      
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 839  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
Publication
First Author: Hoshino H
Year: 2000
Journal: J Biol Chem
Title: Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element.
Volume: 275
Issue: 20
Pages: 15370-6
Allele
Name: BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 2.1, Kazuhiko Igarashi
Allele Type: Targeted
Attribute String: Reporter
Interaction Experiment
Description: Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.
Interaction Experiment
Description: Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells.
Publication
First Author: Ochiai K
Year: 2006
Journal: J Biol Chem
Title: Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells.
Volume: 281
Issue: 50
Pages: 38226-34
Allele
Name: BTB and CNC homology, basic leucine zipper transcription factor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: regulatory region 79; endonuclease-mediated mutation 2, Ryan Tewhey
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
DO Term
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Rr79/Rr79
Background: C57BL/6J-Rr79/J
Zygosity: hm
Has Mutant Allele: true
Allele
Name: BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 2.1, Tomohiro Kurosaki
Allele Type: Targeted
Attribute String: Epitope tag
Allele
Name: BTB and CNC homology, basic leucine zipper transcription factor 2; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
Strain
Attribute String: mutant strain, coisogenic, chemically induced mutation
Genotype
Symbol: Bach2/Bach2
Background: C57BL/6J-Bach2
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Chen Z
Year: 2013
Journal: PLoS One
Title: Nuclear translocation of B-cell-specific transcription factor, BACH2, modulates ROS mediated cytotoxic responses in mantle cell lymphoma.
Volume: 8
Issue: 8
Pages: e69126
Publication
First Author: Okita Y
Year: 2013
Journal: J Biol Chem
Title: Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.
Volume: 288
Issue: 28
Pages: 20658-67
Publication
First Author: Liang Y
Year: 2012
Journal: J Biol Chem
Title: Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis.
Volume: 287
Issue: 40
Pages: 33533-44
Protein Domain
Type: Domain
Description: BACH proteins are Cap'n'Collar (CNC) Basic leucine zipper (bZIP) transcription factors that are defined by a conserved 43-amino acid region (called the CNC domain) located N-terminal to the bZIP DNA-binding domain. In addition, they contain a BTB domain (Broad complex-Tramtrack-Bric-a-brac domain, also known as the POZ [poxvirus and zinc finger]domain) that is absent in other CNC proteins. Veterbrates contain two members, BACH1 and BACH2. BACH1 forms heterodimers with small Mafs such as MafK to function as a repressor of heme oxygenase-1 (HO-1) gene (Hmox-1) enhancers []. It has also been implicated as the master regulator of breast cancer bone metastasis []. The BACH1 bZIP transcription factor should not be confused with the protein originally named as BRCA1-Associated C-terminal Helicase1 (BACH1), which has been renamed BRIP1 (BRCA1 Interacting Protein C-terminal Helicase1) and also called FANCJ. BACH2 is a B-cell specific transcription factor that plays a critical role in oxidative stress-mediated apoptosis []. It plays an important role in class switching and somatic hypermutation of immunoglobulin genes [].
Publication
First Author: Venturutti L
Year: 2020
Journal: Cell
Title: TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
Volume: 182
Issue: 2
Pages: 297-316.e27
Publication  
First Author: Verma M
Year: 2021
Journal: J Exp Med
Title: The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma.
Volume: 218
Issue: 7
Publication
First Author: Utzschneider DT
Year: 2020
Journal: Nat Immunol
Title: Early precursor T cells establish and propagate T cell exhaustion in chronic infection.
Volume: 21
Issue: 10
Pages: 1256-1266
Genotype
Symbol: Rr79/Rr79 Tg(TcraTcrb)1100Mjb/?
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Kharabi Masouleh B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.
Volume: 111
Issue: 21
Pages: E2219-28
Publication  
First Author: Horiuchi S
Year: 2023
Journal: Front Immunol
Title: SpiB regulates the expression of B-cell-related genes and increases the longevity of memory B cells.
Volume: 14
Pages: 1250719
Publication  
First Author: Hilliard S
Year: 2019
Journal: Biol Open
Title: Defining the dynamic chromatin landscape of mouse nephron progenitors.
Volume: 8
Issue: 5
Publication
First Author: Suzuki H
Year: 2003
Journal: J Biol Chem
Title: Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene.
Volume: 278
Issue: 49
Pages: 49246-53