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Search results 301 to 399 out of 399 for Bmx

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Type Details Score
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
11114746 | -
First Author: Qiu Y
Year: 2000
Journal: Oncogene
Title: Signaling network of the Btk family kinases.
Volume: 19
Issue: 49
Pages: 5651-61
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Publication
11340625 | -
First Author: Smith CI
Year: 2001
Journal: Bioessays
Title: The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.
Volume: 23
Issue: 5
Pages: 436-46
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Publication
17624943 | -
 
First Author: Gomez-Rodriguez J
Year: 2007
Journal: Immunol Rev
Title: Tec kinases, actin, and cell adhesion.
Volume: 218
Pages: 45-64
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Allele
Bmx<em1Smoc> | MGI:7288507
Name: BMX non-receptor tyrosine kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Bmx<+> | MGI:2434934
   
Name: BMX non-receptor tyrosine kinase; wild type
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Allele
Bmx<tm1Ali> | MGI:2660714
Name: BMX non-receptor tyrosine kinase; targeted mutation 1, Kari Alitalo
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Bmx<Gt(OST464415)Lex> | MGI:4325970
 
Name: BMX non-receptor tyrosine kinase; gene trap OST464415, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Bmx<tm1.1Npa> | MGI:5013470
 
Name: BMX non-receptor tyrosine kinase; targeted mutation 1.1, Novartis Pharma AG
Allele Type: Targeted
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Allele
Bmx<tm1(KOMP)Vlcg> | MGI:5292935
Name: BMX non-receptor tyrosine kinase; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Bmx<em1Gpt> | MGI:7295956
Name: BMX non-receptor tyrosine kinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Bmx<em4Gpt> | MGI:7295957
Name: BMX non-receptor tyrosine kinase; endonuclease-mediated mutation 4, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Bmx<em1Cya> | MGI:7582615
Name: BMX non-receptor tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Bmx<em2Cya> | MGI:7582616
Name: BMX non-receptor tyrosine kinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Bmx<tm1a(EUCOMM)Wtsi> | MGI:4433142
Name: BMX non-receptor tyrosine kinase; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:5013622 | BALB/c-Bmx<tm1.1Npa>
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Bmx<tm1b(EUCOMM)Wtsi> | MGI:5548403
Name: BMX non-receptor tyrosine kinase; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Bmx<tm1c(EUCOMM)Wtsi> | MGI:7861240
Name: BMX non-receptor tyrosine kinase; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:7590920 | C57BL/6J-Bmx<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7588128 | C57BL/6J-Bmx<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Bmx<em2Smoc> | MGI:7750392
Name: BMX non-receptor tyrosine kinase; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Bmx/Bmx
Background: involves: 129S1/Sv * 129X1/SvJ * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmx/Bmx
Background: BALB/c-Bmx
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmx/Bmx
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5557568 | C57BL/6NTac-Bmx<tm1a(EUCOMM)Wtsi>/IcsOrl
Attribute String: coisogenic, targeted mutation
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Strain
MGI:5630439 | C57BL/6N-Bmx<tm1b(EUCOMM)Wtsi>/Ics
Attribute String: coisogenic, targeted mutation
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Strain
MGI:7861241 | C57BL/6N-Bmx<tm1c(EUCOMM)Wtsi>/Oulu
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:7764352 | C57BL/6JSmoc-Bmx<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Bmx/Bmx<+>
Background: involves: 129S1/Sv * 129X1/SvJ * DBA/2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmx/?
Background: C57BL/6N-Bmx/Ics
Zygosity: ot
Has Mutant Allele: true
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Publication
14993283 | J:89059
First Author: Tomlinson MG
Year: 2004
Journal: Mol Cell Biol
Title: Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec.
Volume: 24
Issue: 6
Pages: 2455-66
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Allele
Tg(Bmx-cre/ERT2)1Rha | MGI:5513853
Name: transgene insertion 1, Ralf H Adams
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Ace2<tm1.1(ACE2)Mdk> | MGI:6509009
Name: angiotensin converting enzyme 2; targeted mutation 1.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6509010 | B6(Cg)-Ace2<tm1.1(ACE2)Mdk>/J
Attribute String: mutant strain, targeted mutation
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Protein Domain
IPR035875 | BMX_SH2
Type: Domain
Description: Cytoplasmic tyrosine-protein kinase BMX (bone marrow tyrosine kinase gene on chromosome X, also known as ETK) is a non-receptor tyrosine kinase (). It plays central but diverse modulator roles in various signalling processes involved in the regulation of actin reorganisation, cell migration, cell proliferation and survival, cell adhesion, and apoptosis [, , ]. It has a role in inflammation, cardiovascular disease, and cancer []. It is activated downstream of phosphatidylinositol-3 kinase (PI3K) and the kinase Src [].This entry represents the SH2 domain of BMX.
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Strain
MGI:6438643 | B6.Cg-Tg(Bmx-cre/ERT2)1Rha/Tac
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:7570921 | B6.Cg-Tg(Bmx-cre/ERT2)1Rha/H
Attribute String: transgenic, congenic, mutant strain
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Publication
38727309 | J:348358
 
First Author: Mussbacher M
Year: 2024
Journal: Cells
Title: Effects of Chronic Inflammatory Activation of Murine and Human Arterial Endothelial Cells at Normal Lipoprotein and Cholesterol Levels In Vivo and In Vitro.
Volume: 13
Issue: 9
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Rbpj/Rbpj Tg(Bmx-cre/ERT2)1Rha/?
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Bmx-cre/ERT2)1Rha/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
20937974 | J:179483
First Author: Bry M
Year: 2010
Journal: Circulation
Title: Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation.
Volume: 122
Issue: 17
Pages: 1725-33
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Publication
22640808 | J:185527
First Author: Yan J
Year: 2012
Journal: Am J Pathol
Title: Bone marrow ablation demonstrates that excess endogenous parathyroid hormone plays distinct roles in trabecular and cortical bone.
Volume: 181
Issue: 1
Pages: 234-44
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Publication
28650109 | J:278157
First Author: Xu W
Year: 2017
Journal: J Bone Miner Res
Title: Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation.
Volume: 32
Issue: 11
Pages: 2194-2206
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Publication
11859127 | -
First Author: Takeba Y
Year: 2002
Journal: J Immunol
Title: Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription.
Volume: 168
Issue: 5
Pages: 2365-70
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Protein Domain
IPR035870 | Txk_SH2
Type: Domain
Description: Txk is a member of the Tec protein tyrosine kinase family. It plays a role in TCR signal transduction, T cell development, and selection which is analogous to the function of Itk. Txk has been shown to interact with IFN-gamma [, ]. Unlike most of the Tec family members Txk lacks a PH domain. Instead Txk has a unique region containing a palmitoylated cysteine string which has a similar membrane tethering function as the PH domain []. This entry includes the SH2 domain of Txk.The Tec protein tyrosine kinase family includes Tec,Btk, Itk, Bmx, and Txk. They contain an NH2-terminal pleckstrin homology (PH) domain (absent in Txk), a proline-rich region, Src-homology 3 (SH3) and SH2 domains, and a COOH-terminal PTK domain. The TH domain consists of a Zn2+-binding Btk motif and a proline-rich region. The Btk motif is found in Tec kinases, Ras GAP, and IGBP and crucial to the function of the PH domain. It is not present in Txk which is not surprising since it lacks a PH domain. The type 1 splice form of the Drosophila homologue also lacks both the PH domain and the Btk motif. The proline-rich regions are highly conserved for the most part with the exception of Bmx whose residues surrounding the PXXP motif are not conserved (TH-like) and Btk29A which is entirely unique with large numbers of glycine residues (TH-extended). Tec family members all lack a C-terminal tyrosine having an autoinhibitory function in its phosphorylated state [, ].
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Publication
24584117 | J:210259
First Author: Schober A
Year: 2014
Journal: Nat Med
Title: MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1.
Volume: 20
Issue: 4
Pages: 368-76
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Publication
27146149 | J:254103
 
First Author: Nakagawa A
Year: 2016
Journal: Sci Rep
Title: Activation of endothelial β-catenin signaling induces heart failure.
Volume: 6
Pages: 25009
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Publication
24723559 | J:223610
First Author: Noels H
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice.
Volume: 34
Issue: 6
Pages: 1209-20
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Publication
34910626 | J:316417
   
First Author: Phansalkar R
Year: 2021
Journal: Elife
Title: Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development.
Volume: 10
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Bmx-cre/ERT2)1Rha/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
17177976 | -
First Author: Maruyama T
Year: 2007
Journal: Clin Exp Immunol
Title: Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells.
Volume: 147
Issue: 1
Pages: 164-75
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Publication
20206686 | -
First Author: Bradshaw JM
Year: 2010
Journal: Cell Signal
Title: The Src, Syk, and Tec family kinases: distinct types of molecular switches.
Volume: 22
Issue: 8
Pages: 1175-84
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Publication
37023750 | J:335167
First Author: Lu P
Year: 2023
Journal: Dev Cell
Title: Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis.
Volume: 58
Issue: 9
Pages: 791-805.e4
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Publication
29429943 | J:260400
First Author: Wakabayashi T
Year: 2018
Journal: Cell Stem Cell
Title: CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.
Volume: 22
Issue: 3
Pages: 384-397.e6
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Publication
28450349 | J:265371
First Author: Döring Y
Year: 2017
Journal: Circulation
Title: Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.
Volume: 136
Issue: 4
Pages: 388-403
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Publication
34497373 | J:317975
First Author: Lu P
Year: 2021
Journal: Nat Cell Biol
Title: Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling.
Volume: 23
Issue: 9
Pages: 967-977
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Publication
36347256 | J:331483
First Author: D'Amato G
Year: 2022
Journal: Dev Cell
Title: Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4.
Volume: 57
Issue: 22
Pages: 2517-2532.e6
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Publication
25920569 | J:239279
First Author: Kidoya H
Year: 2015
Journal: Dev Cell
Title: APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.
Volume: 33
Issue: 3
Pages: 247-59
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Publication
29934585 | J:274316
First Author: Xu C
Year: 2018
Journal: Nat Commun
Title: Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Volume: 9
Issue: 1
Pages: 2449
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Publication
31702554 | J:282834
   
First Author: Gancz D
Year: 2019
Journal: Elife
Title: Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration.
Volume: 8
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Publication
35440634 | J:325750
First Author: Fleig S
Year: 2022
Journal: Nat Commun
Title: Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures.
Volume: 13
Issue: 1
Pages: 2022
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Publication
23785053 | J:198633
First Author: Ehling M
Year: 2013
Journal: Development
Title: Notch controls retinal blood vessel maturation and quiescence.
Volume: 140
Issue: 14
Pages: 3051-61
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Publication
31761723 | J:291766
First Author: Chen Q
Year: 2019
Journal: Cell Stem Cell
Title: Apelin+ Endothelial Niche Cells Control Hematopoiesis and Mediate Vascular Regeneration after Myeloablative Injury.
Volume: 25
Issue: 6
Pages: 768-783.e6
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Publication
35288551 | J:322701
First Author: Liu Y
Year: 2022
Journal: Nat Commun
Title: A specialized bone marrow microenvironment for fetal haematopoiesis.
Volume: 13
Issue: 1
Pages: 1327
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Publication
25468970 | J:217811
First Author: Murphy PA
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels.
Volume: 111
Issue: 50
Pages: 18007-12
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Publication
39087029 | J:358640
 
First Author: Antila S
Year: 2024
Journal: Nat Cardiovasc Res
Title: Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer's disease-related amyloid pathology.
Volume: 3
Pages: 474-491
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Publication
34474596 | J:336605
First Author: Lee HW
Year: 2021
Journal: Circulation
Title: Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis.
Volume: 144
Issue: 16
Pages: 1308-1322
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Publication
32076269 | J:293815
First Author: Chow BW
Year: 2020
Journal: Nature
Title: Caveolae in CNS arterioles mediate neurovascular coupling.
Volume: 579
Issue: 7797
Pages: 106-110
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Publication
27576369 | J:241907
 
First Author: Gamrekelashvili J
Year: 2016
Journal: Nat Commun
Title: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.
Volume: 7
Pages: 12597
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Publication
33333021 | J:301487
First Author: Huang S
Year: 2021
Journal: Cell
Title: Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential.
Volume: 184
Issue: 2
Pages: 441-459.e25
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Publication
35508166 | J:324828
First Author: Emoto T
Year: 2022
Journal: Immunity
Title: Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche.
Volume: 55
Issue: 5
Pages: 862-878.e8
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Protein
P42682
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Protein
Q0VBP6
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Protein
B2RQ20
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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