Type |
Details |
Score |
Publication |
First Author: |
Sheerin NS |
Year: |
1997 |
Journal: |
Clin Exp Immunol |
Title: |
Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice. |
Volume: |
110 |
Issue: |
3 |
Pages: |
403-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zachrau B |
Year: |
2004 |
Journal: |
Int Immunol |
Title: |
Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice. |
Volume: |
16 |
Issue: |
12 |
Pages: |
1685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sponarova J |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Efficient amyloid A clearance in the absence of immunoglobulins and complement factors. |
Volume: |
182 |
Issue: |
4 |
Pages: |
1297-307 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi M |
Year: |
2010 |
Journal: |
J Exp Med |
Title: |
Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D. |
Volume: |
207 |
Issue: |
1 |
Pages: |
29-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Locker J |
Year: |
1990 |
Journal: |
Immunogenetics |
Title: |
The rat MHC and cystathionine beta-synthase gene are syntenic on chromosome 20. |
Volume: |
31 |
Issue: |
4 |
Pages: |
271-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hughes AL |
Year: |
1994 |
Journal: |
Mol Biol Evol |
Title: |
Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first. |
Volume: |
11 |
Issue: |
3 |
Pages: |
417-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rawal N |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Formation of high affinity C5 convertase of the classical pathway of complement. |
Volume: |
278 |
Issue: |
40 |
Pages: |
38476-83 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
742
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
141
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang T |
Year: |
1997 |
Journal: |
J Exp Med |
Title: |
A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis. |
Volume: |
186 |
Issue: |
11 |
Pages: |
1853-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaspal FM |
Year: |
2006 |
Journal: |
Eur J Immunol |
Title: |
The generation of thymus-independent germinal centers depends on CD40 but not on CD154, the T cell-derived CD40-ligand. |
Volume: |
36 |
Issue: |
7 |
Pages: |
1665-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Girardi G |
Year: |
2003 |
Journal: |
J Clin Invest |
Title: |
Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. |
Volume: |
112 |
Issue: |
11 |
Pages: |
1644-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Markiewski MM |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Modulation of the antitumor immune response by complement. |
Volume: |
9 |
Issue: |
11 |
Pages: |
1225-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang YS |
Year: |
2006 |
Journal: |
Cell |
Title: |
A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. |
Volume: |
125 |
Issue: |
1 |
Pages: |
47-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quartier P |
Year: |
2005 |
Journal: |
Eur J Immunol |
Title: |
Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro. |
Volume: |
35 |
Issue: |
1 |
Pages: |
252-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mehlhop E |
Year: |
2006 |
Journal: |
J Exp Med |
Title: |
Protective immune responses against West Nile virus are primed by distinct complement activation pathways. |
Volume: |
203 |
Issue: |
5 |
Pages: |
1371-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang C |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2078 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao H |
Year: |
2007 |
Journal: |
Am J Pathol |
Title: |
Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies. |
Volume: |
170 |
Issue: |
1 |
Pages: |
52-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng Q |
Year: |
2008 |
Journal: |
Blood |
Title: |
Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. |
Volume: |
111 |
Issue: |
4 |
Pages: |
2452-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ali YM |
Year: |
2012 |
Journal: |
PLoS Pathog |
Title: |
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection. |
Volume: |
8 |
Issue: |
7 |
Pages: |
e1002793 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cunnion KM |
Year: |
2004 |
Journal: |
J Lab Clin Med |
Title: |
Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia. |
Volume: |
143 |
Issue: |
6 |
Pages: |
358-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zabel MD |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis. |
Volume: |
179 |
Issue: |
9 |
Pages: |
6144-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ochsenbein AF |
Year: |
1999 |
Journal: |
J Exp Med |
Title: |
Protective T cell-independent antiviral antibody responses are dependent on complement. |
Volume: |
190 |
Issue: |
8 |
Pages: |
1165-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haas KM |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression. |
Volume: |
183 |
Issue: |
6 |
Pages: |
3661-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bora NS |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H. |
Volume: |
177 |
Issue: |
3 |
Pages: |
1872-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou W |
Year: |
2000 |
Journal: |
J Clin Invest |
Title: |
Predominant role for C5b-9 in renal ischemia/reperfusion injury. |
Volume: |
105 |
Issue: |
10 |
Pages: |
1363-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Møller-Kristensen M |
Year: |
2007 |
Journal: |
J Invest Dermatol |
Title: |
Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice. |
Volume: |
127 |
Issue: |
6 |
Pages: |
1524-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fossati-Jimack L |
Year: |
2015 |
Journal: |
Immunology |
Title: |
Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency. |
Volume: |
144 |
Issue: |
1 |
Pages: |
149-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Otten MA |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice. |
Volume: |
183 |
Issue: |
6 |
Pages: |
3980-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davis AP |
Year: |
1990 |
Journal: |
Immunogenetics |
Title: |
Complexity at the mouse minor histocompatibility locus H-4. |
Volume: |
31 |
Issue: |
1 |
Pages: |
7-12 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
383
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1738
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1738
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1735
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1735
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1738
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1716
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Gardner SM |
Year: |
1987 |
Journal: |
J Immunol |
Title: |
Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position. |
Volume: |
139 |
Issue: |
2 |
Pages: |
476-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trendelenburg M |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The role of complement in cryoglobulin-induced immune complex glomerulonephritis. |
Volume: |
175 |
Issue: |
10 |
Pages: |
6909-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bergthaler A |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Impaired antibody response causes persistence of prototypic T cell-contained virus. |
Volume: |
7 |
Issue: |
4 |
Pages: |
e1000080 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mold C |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Protection from Streptococcus pneumoniae infection by C-reactive protein and natural antibody requires complement but not Fc gamma receptors. |
Volume: |
168 |
Issue: |
12 |
Pages: |
6375-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2005 |
Journal: |
Science |
Title: |
Divergent immunoglobulin g subclass activity through selective Fc receptor binding. |
Volume: |
310 |
Issue: |
5753 |
Pages: |
1510-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moulton EA |
Year: |
2008 |
Journal: |
PLoS Pathog |
Title: |
Surviving mousepox infection requires the complement system. |
Volume: |
4 |
Issue: |
12 |
Pages: |
e1000249 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mao D |
Year: |
2003 |
Journal: |
Immunity |
Title: |
Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. |
Volume: |
19 |
Issue: |
6 |
Pages: |
813-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verschoor A |
Year: |
2011 |
Journal: |
Nat Immunol |
Title: |
A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3. |
Volume: |
12 |
Issue: |
12 |
Pages: |
1194-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Banda NK |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis. |
Volume: |
185 |
Issue: |
9 |
Pages: |
5598-606 |
|
•
•
•
•
•
|
Publication |
First Author: |
Banda NK |
Year: |
2011 |
Journal: |
Mol Immunol |
Title: |
Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement. |
Volume: |
49 |
Issue: |
1-2 |
Pages: |
281-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baudino L |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens. |
Volume: |
111 |
Issue: |
4 |
Pages: |
1503-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lesher AM |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis. |
Volume: |
24 |
Issue: |
1 |
Pages: |
53-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abonia JP |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle. |
Volume: |
174 |
Issue: |
11 |
Pages: |
7285-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Di Liberto G |
Year: |
2018 |
Journal: |
Cell |
Title: |
Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping. |
Volume: |
175 |
Issue: |
2 |
Pages: |
458-471.e19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rattan A |
Year: |
2017 |
Journal: |
PLoS Pathog |
Title: |
Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection. |
Volume: |
13 |
Issue: |
3 |
Pages: |
e1006248 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu C |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling. |
Volume: |
201 |
Issue: |
12 |
Pages: |
3717-3730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tyan ML |
Year: |
1993 |
Journal: |
Proc Soc Exp Biol Med |
Title: |
Vitamin A-enhanced cleft palate susceptibility gene maps between C4 and B144 within the H-2 complex. |
Volume: |
202 |
Issue: |
4 |
Pages: |
482-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samollow PB |
Year: |
1986 |
Journal: |
J Immunogenet |
Title: |
Electrophoretic analysis of liver neuraminidase-1 variation in mice and additional evidence concerning the location of NEU-1. |
Volume: |
13 |
Issue: |
1 |
Pages: |
29-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sertić J |
Year: |
1990 |
Journal: |
Genomics |
Title: |
Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17. |
Volume: |
6 |
Issue: |
3 |
Pages: |
560-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vernet C |
Year: |
1995 |
Journal: |
Mamm Genome |
Title: |
Mapping of 12 markers in the proximal region of mouse chromosome 17 using recombinant t haplotypes. |
Volume: |
6 |
Issue: |
3 |
Pages: |
219-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Douglas TC |
Year: |
1979 |
Journal: |
Immunogenetics |
Title: |
The position of the gene for glyoxylase I on Chromosome 17 of the mouse. |
Volume: |
8 |
|
Pages: |
367-371 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1221
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
705
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
705
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
705
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
594
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
727
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1663
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gordan S |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity. |
Volume: |
29 |
Issue: |
10 |
Pages: |
3033-3046.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim DD |
Year: |
2008 |
Journal: |
Blood |
Title: |
Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg. |
Volume: |
112 |
Issue: |
4 |
Pages: |
1109-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miwa T |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Blocking properdin, the alternative pathway, and anaphylatoxin receptors ameliorates renal ischemia-reperfusion injury in decay-accelerating factor and CD59 double-knockout mice. |
Volume: |
190 |
Issue: |
7 |
Pages: |
3552-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pinto AK |
Year: |
2014 |
Journal: |
PLoS Pathog |
Title: |
Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis. |
Volume: |
10 |
Issue: |
4 |
Pages: |
e1004086 |
|
•
•
•
•
•
|
Publication |
First Author: |
Subramanian S |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Epistatic suppression of systemic lupus erythematosus: fine mapping of Sles1 to less than 1 mb. |
Volume: |
175 |
Issue: |
2 |
Pages: |
1062-72 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1680
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie S |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Genetic contributions of nonautoimmune SWR mice toward lupus nephritis. |
Volume: |
167 |
Issue: |
12 |
Pages: |
7141-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshino M |
Year: |
1994 |
Journal: |
Immunogenetics |
Title: |
Recombination in the class III region of the mouse major histocompatibility complex. |
Volume: |
40 |
Issue: |
4 |
Pages: |
280-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haston CK |
Year: |
2005 |
Journal: |
J Med Genet |
Title: |
Murine candidate bleomycin induced pulmonary fibrosis susceptibility genes identified by gene expression and sequence analysis of linkage regions. |
Volume: |
42 |
Issue: |
6 |
Pages: |
464-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stark K |
Year: |
2024 |
Journal: |
Immunity |
Title: |
Antibodies and complement are key drivers of thrombosis. |
Volume: |
57 |
Issue: |
9 |
Pages: |
2140-2156.e10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou T |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice. |
Volume: |
13 |
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MGI Direct Data Submission |
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MGI Direct Data Submission |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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UniProt-GOA |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Gene Ontology annotation through association of InterPro records with GO terms |
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