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Search results 301 to 380 out of 380 for Ccl19

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Type Details Score
Publication
26637788 | J:260103
   
First Author: Mair F
Year: 2015
Journal: Elife
Title: The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells.
Volume: 4
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Publication
34919443 | J:332782
First Author: Wu D
Year: 2021
Journal: Sci Immunol
Title: IL-17-dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10-producing B cells.
Volume: 6
Issue: 66
Pages: eaao3669
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Publication
33903764 | J:305302
First Author: Kapoor VN
Year: 2021
Journal: Nat Immunol
Title: Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues.
Volume: 22
Issue: 5
Pages: 571-585
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Publication
35024041 | J:346570
 
First Author: Li X
Year: 2021
Journal: Front Immunol
Title: Kidney-Draining Lymph Node Fibrosis Following Unilateral Ureteral Obstruction.
Volume: 12
Pages: 768412
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Publication
27415420 | J:274709
First Author: Novkovic M
Year: 2016
Journal: PLoS Biol
Title: Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality.
Volume: 14
Issue: 7
Pages: e1002515
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Publication
32700362 | J:302215
First Author: Aparicio-Domingo P
Year: 2021
Journal: Eur J Immunol
Title: Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection.
Volume: 51
Issue: 1
Pages: 76-90
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Myd88/Myd88 Tg(Ccl19-cre)489Biat/?
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
8383238 | -
First Author: Birkenbach M
Year: 1993
Journal: J Virol
Title: Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors.
Volume: 67
Issue: 4
Pages: 2209-20
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Publication
9153236 | -
First Author: Yoshida R
Year: 1997
Journal: J Biol Chem
Title: Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7.
Volume: 272
Issue: 21
Pages: 13803-9
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Publication
11745346 | -
First Author: Bardi G
Year: 2001
Journal: Eur J Immunol
Title: The T cell chemokine receptor CCR7 is internalized on stimulation with ELC, but not with SLC.
Volume: 31
Issue: 11
Pages: 3291-7
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Publication
16278415 | -
First Author: Kim JW
Year: 2005
Journal: Clin Cancer Res
Title: Chemokine C receptor 7 expression and protection of circulating CD8+ T lymphocytes from apoptosis.
Volume: 11
Issue: 21
Pages: 7901-10
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Publication
15778365 | -
First Author: Riol-Blanco L
Year: 2005
Journal: J Immunol
Title: The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed.
Volume: 174
Issue: 7
Pages: 4070-80
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Publication
15059845 | -
First Author: Sánchez-Sánchez N
Year: 2004
Journal: Blood
Title: Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells.
Volume: 104
Issue: 3
Pages: 619-25
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Publication
12019175 | -
First Author: Mashino K
Year: 2002
Journal: Cancer Res
Title: Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma.
Volume: 62
Issue: 10
Pages: 2937-41
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Publication
12673677 | -
First Author: Takanami I
Year: 2003
Journal: Int J Cancer
Title: Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis.
Volume: 105
Issue: 2
Pages: 186-9
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Publication
12960129 | -
First Author: Ding Y
Year: 2003
Journal: Clin Cancer Res
Title: Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma.
Volume: 9
Issue: 9
Pages: 3406-12
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Publication
17560334 | -
First Author: Shields JD
Year: 2007
Journal: Cancer Cell
Title: Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling.
Volume: 11
Issue: 6
Pages: 526-38
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Publication
10520991 | J:57976
First Author: Förster R
Year: 1999
Journal: Cell
Title: CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
Volume: 99
Issue: 1
Pages: 23-33
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Protein Domain
IPR001718 | Chemokine_CCR7
Type: Family
Description: Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helper cells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).CC chemokine receptors are a subfamily of the chemokine receptors that specifically bind and respond to cytokines of the CC chemokine family. There are currently ten members of the CC chemokine receptor subfamily, named CCR1 to 10. The receptors receptors are found in monocytes, lymphocytes, basophils and eosinophils.This entry represents CC chemokine receptor 7 (CCR7). It is expressed in various lymphoid tissues and plays an important role in the regulation of the homing and traffic of lymphocytes into and within secondary lymphoid tissues [, , , ]. It has also been shown to induce antiapoptotic signaling in mature dendritic cells []. CCR7 is seen as an important organiser of the primary immune response []. CCR7 is also expressed by various cancer cells, such as non-small lung cancer, gastric cancer and oesophageal cancer [, , ]and the expression of CCR7 by cancer cells has been linked with metastasis to lymph nodes []. CCR7 binds CCL19 and CCL21 [].
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
33746953 | J:324351
 
First Author: Santopaolo M
Year: 2021
Journal: Front Immunol
Title: Activation of Bone Marrow Adaptive Immunity in Type 2 Diabetes: Rescue by Co-stimulation Modulator Abatacept.
Volume: 12
Pages: 609406
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Publication
27936218 | J:256803
First Author: Olguín-Alor R
Year: 2016
Journal: PLoS One
Title: A Key Role for Inhibins in Dendritic Cell Maturation and Function.
Volume: 11
Issue: 12
Pages: e0167813
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Publication
12969314 | J:85493
 
First Author: Tumanov AV
Year: 2003
Journal: Immunol Rev
Title: Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting.
Volume: 195
Pages: 106-16
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Publication
36630476 | J:360538
First Author: Osorio EY
Year: 2023
Journal: PLoS Negl Trop Dis
Title: Malnutrition-related parasite dissemination from the skin in visceral leishmaniasis is driven by PGE2-mediated amplification of CCR7-related trafficking of infected inflammatory monocytes.
Volume: 17
Issue: 1
Pages: e0011040
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Publication
17982037 | J:153869
First Author: Ziegler E
Year: 2007
Journal: J Immunol
Title: CCR7 signaling inhibits T cell proliferation.
Volume: 179
Issue: 10
Pages: 6485-93
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Publication
20194594 | J:159183
First Author: Noor S
Year: 2010
Journal: Infect Immun
Title: CCR7-dependent immunity during acute Toxoplasma gondii infection.
Volume: 78
Issue: 5
Pages: 2257-63
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Publication
16314534 | J:103752
First Author: Liu E
Year: 2005
Journal: Mol Cell Biol
Title: Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival.
Volume: 25
Issue: 24
Pages: 11145-55
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Publication
15845449 | J:97986
First Author: Kabashima K
Year: 2005
Journal: Immunity
Title: Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.
Volume: 22
Issue: 4
Pages: 439-50
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Publication
15240672 | J:91926
First Author: Yopp AC
Year: 2004
Journal: J Immunol
Title: FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.
Volume: 173
Issue: 2
Pages: 855-65
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Publication
15857154 | J:99611
First Author: Okada T
Year: 2005
Journal: PLoS Biol
Title: Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells.
Volume: 3
Issue: 6
Pages: e150
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Publication
19427241 | J:149548
First Author: Rangel-Moreno J
Year: 2009
Journal: Immunity
Title: Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens.
Volume: 30
Issue: 5
Pages: 731-43
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Publication
32198221 | J:337969
 
First Author: Dasoveanu DC
Year: 2020
Journal: Sci Immunol
Title: Lymph node stromal CCL2 limits antibody responses.
Volume: 5
Issue: 45
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Publication
23554941 | J:200168
First Author: Walsh MP
Year: 2013
Journal: PLoS One
Title: Val-boroPro accelerates T cell priming via modulation of dendritic cell trafficking resulting in complete regression of established murine tumors.
Volume: 8
Issue: 3
Pages: e58860
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Publication
28319044 | J:243607
First Author: Chung J
Year: 2017
Journal: J Clin Invest
Title: Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Volume: 127
Issue: 4
Pages: 1574-1588
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Publication
27798617 | J:259569
First Author: Gil-Cruz C
Year: 2016
Journal: Nat Immunol
Title: Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs.
Volume: 17
Issue: 12
Pages: 1388-1396
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Publication
34706240 | J:321167
First Author: Menzel L
Year: 2021
Journal: Cell Rep
Title: Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Volume: 37
Issue: 4
Pages: 109878
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Publication
35440118 | J:337391
First Author: Cheng HW
Year: 2022
Journal: Nat Commun
Title: Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function.
Volume: 13
Issue: 1
Pages: 2027
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Publication
21300913 | J:176844
First Author: Lei Y
Year: 2011
Journal: J Exp Med
Title: Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development.
Volume: 208
Issue: 2
Pages: 383-94
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Publication
25347465 | J:222319
First Author: Astarita JL
Year: 2015
Journal: Nat Immunol
Title: The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.
Volume: 16
Issue: 1
Pages: 75-84
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Publication
35111151 | J:326683
 
First Author: Jiang L
Year: 2021
Journal: Front Immunol
Title: Characterization of Leptin Receptor+ Stromal Cells in Lymph Node.
Volume: 12
Pages: 730438
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Publication
31116987 | J:284427
First Author: Dubey LK
Year: 2019
Journal: Cell Rep
Title: IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells.
Volume: 27
Issue: 8
Pages: 2442-2458.e5
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Publication
35315876 | J:331109
 
First Author: Kim D
Year: 2022
Journal: J Exp Med
Title: Lymph node fibroblastic reticular cells regulate differentiation and function of CD4 T cells via CD25.
Volume: 219
Issue: 5
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Publication
19468301 | J:150671
First Author: Greter M
Year: 2009
Journal: PLoS Biol
Title: Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity.
Volume: 7
Issue: 5
Pages: e1000109
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Publication
30097537 | J:275390
 
First Author: Perez-Shibayama C
Year: 2018
Journal: Sci Immunol
Title: Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity.
Volume: 3
Issue: 26
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Publication
18056347 | J:155040
First Author: Zhu M
Year: 2007
Journal: J Immunol
Title: Lymphotoxin beta receptor is required for the migration and selection of autoreactive T cells in thymic medulla.
Volume: 179
Issue: 12
Pages: 8069-75
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Publication
31201093 | J:282508
First Author: Camara A
Year: 2019
Journal: Immunity
Title: Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.
Volume: 50
Issue: 6
Pages: 1467-1481.e6
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Publication
29652930 | J:278378
First Author: Baumann NS
Year: 2018
Journal: PLoS Pathog
Title: Tissue maintenance of CMV-specific inflationary memory T cells by IL-15.
Volume: 14
Issue: 4
Pages: e1006993
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Publication
35031565 | J:325380
 
First Author: Camara A
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: CD169+ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling.
Volume: 119
Issue: 3
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Publication
30962593 | J:282323
First Author: Majumder S
Year: 2019
Journal: Nat Immunol
Title: IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.
Volume: 20
Issue: 5
Pages: 534-545
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Publication
25151489 | J:260606
First Author: Cremasco V
Year: 2014
Journal: Nat Immunol
Title: B cell homeostasis and follicle confines are governed by fibroblastic reticular cells.
Volume: 15
Issue: 10
Pages: 973-81
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Protein Coding Gene
MGI:103011 | Ccr7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21844396 | J:179238
First Author: Kelly LM
Year: 2011
Journal: J Immunol
Title: EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues.
Volume: 187
Issue: 6
Pages: 3026-32
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Publication
19822644 | J:154064
First Author: Nagatake T
Year: 2009
Journal: J Exp Med
Title: Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity.
Volume: 206
Issue: 11
Pages: 2351-64
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Publication
39141517 | J:353914
First Author: Bessell E
Year: 2024
Journal: Cell Rep
Title: Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity.
Volume: 43
Issue: 8
Pages: 114620
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Publication
36809763 | J:347462
First Author: Marx AF
Year: 2023
Journal: Immunity
Title: The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1(+) CD8(+) T cells in chronic viral infection.
Volume: 56
Issue: 4
Pages: 813-828.e10
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Publication
19805112 | J:153692
First Author: Nitta T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens.
Volume: 106
Issue: 40
Pages: 17129-33
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Publication
22634865 | J:187654
First Author: León B
Year: 2012
Journal: Nat Immunol
Title: Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells.
Volume: 13
Issue: 7
Pages: 681-90
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Publication
34555336 | J:321362
First Author: Duan L
Year: 2021
Journal: Immunity
Title: Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation.
Volume: 54
Issue: 10
Pages: 2256-2272.e6
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Publication
22508930 | J:188667
First Author: Yin N
Year: 2012
Journal: J Immunol
Title: Functional specialization of islet dendritic cell subsets.
Volume: 188
Issue: 10
Pages: 4921-30
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Publication
30429248 | J:268981
First Author: Thierry GR
Year: 2018
Journal: J Exp Med
Title: The conduit system exports locally secreted IgM from lymph nodes.
Volume: 215
Issue: 12
Pages: 2972-2983
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Publication
32298648 | J:289764
First Author: Chauveau A
Year: 2020
Journal: Immunity
Title: Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones.
Volume: 52
Issue: 5
Pages: 794-807.e7
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Publication
34267375 | J:314436
First Author: Cupovic J
Year: 2021
Journal: Nat Immunol
Title: Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells.
Volume: 22
Issue: 8
Pages: 1042-1051
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Publication
26453751 | J:314828
First Author: Rodda LB
Year: 2015
Journal: J Immunol
Title: Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells.
Volume: 195
Issue: 10
Pages: 4781-91
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Publication
39566495 | J:359516
     
First Author: Onder L
Year: 2024
Journal: Cell
Title: Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer.
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Publication
28709801 | J:259045
First Author: Onder L
Year: 2017
Journal: Immunity
Title: Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.
Volume: 47
Issue: 1
Pages: 80-92.e4
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Publication
35817845 | J:344023
First Author: Assen FP
Year: 2022
Journal: Nat Immunol
Title: Multitier mechanics control stromal adaptations in the swelling lymph node.
Volume: 23
Issue: 8
Pages: 1246-1255
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Protein
P47774
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Protein
Q3U3J0
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Publication
26147686 | J:259295
First Author: Bénézech C
Year: 2015
Journal: Nat Immunol
Title: Inflammation-induced formation of fat-associated lymphoid clusters.
Volume: 16
Issue: 8
Pages: 819-828
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Publication
37327322 | J:341050
First Author: Silva-Sanchez A
Year: 2023
Journal: Sci Immunol
Title: Activation of regulatory dendritic cells by Mertk coincides with a temporal wave of apoptosis in neonatal lungs.
Volume: 8
Issue: 84
Pages: eadc9081
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Publication
32562599 | J:305524
First Author: Bellomo A
Year: 2020
Journal: Immunity
Title: Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages.
Volume: 53
Issue: 1
Pages: 127-142.e7
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Publication
30824323 | J:282506
First Author: Dahlgren MW
Year: 2019
Journal: Immunity
Title: Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches.
Volume: 50
Issue: 3
Pages: 707-722.e6
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Publication
- | J:109762
     
First Author: Mouse Genome Informatics and VEGA Genome Database Project
Year: 2006
Journal: Database Release
Title: Collaboration to Associate VEGA (Vertebrate Genome Annotation) Mouse Gene Models with MGI Markers
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Publication
9689100 | J:49070
First Author: Ma Q
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.
Volume: 95
Issue: 16
Pages: 9448-53
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Publication
11544102 | -
First Author: Horuk R
Year: 2001
Journal: Cytokine Growth Factor Rev
Title: Chemokine receptors.
Volume: 12
Issue: 4
Pages: 313-35
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Publication
10601351 | -
First Author: Charbonnier AS
Year: 1999
Journal: J Exp Med
Title: Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal langerhans cells.
Volume: 190
Issue: 12
Pages: 1755-68
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Publication
9500790 | -
First Author: Sallusto F
Year: 1998
Journal: J Exp Med
Title: Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes.
Volume: 187
Issue: 6
Pages: 875-83
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Publication
7592998 | -
First Author: Strieter RM
Year: 1995
Journal: J Biol Chem
Title: The functional role of the ELR motif in CXC chemokine-mediated angiogenesis.
Volume: 270
Issue: 45
Pages: 27348-57
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Publication
10714678 | -
First Author: Zlotnik A
Year: 2000
Journal: Immunity
Title: Chemokines: a new classification system and their role in immunity.
Volume: 12
Issue: 2
Pages: 121-7
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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