|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 1952 for Cdkn2a

0.029s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Shai A
Year: 2015
Journal: Cancer Res
Title: TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis.
Volume: 75
Issue: 15
Pages: 3167-80
Publication  
First Author: Mosteiro L
Year: 2018
Journal: Aging Cell
Title: Senescence promotes in vivo reprogramming through p16INK4a and IL-6.
Volume: 17
Issue: 2
Publication
First Author: Vyazunova I
Year: 2014
Journal: PLoS One
Title: Sleeping Beauty mouse models identify candidate genes involved in gliomagenesis.
Volume: 9
Issue: 11
Pages: e113489
Publication
First Author: Jankovic M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Role of the translocation partner in protection against AID-dependent chromosomal translocations.
Volume: 107
Issue: 1
Pages: 187-92
Publication
First Author: Mattison J
Year: 2010
Journal: Cancer Res
Title: Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.
Volume: 70
Issue: 3
Pages: 883-95
Publication
First Author: Ramiro AR
Year: 2006
Journal: Nature
Title: Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
Volume: 440
Issue: 7080
Pages: 105-9
Publication
First Author: Kang TW
Year: 2011
Journal: Nature
Title: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Volume: 479
Issue: 7374
Pages: 547-51
Publication
First Author: Zhu L
Year: 2016
Journal: Cell
Title: Multi-organ Mapping of Cancer Risk.
Volume: 166
Issue: 5
Pages: 1132-1146.e7
Publication
First Author: Wikenheiser-Brokamp KA
Year: 2006
Journal: Cell Mol Life Sci
Title: Retinoblastoma family proteins: insights gained through genetic manipulation of mice.
Volume: 63
Issue: 7-8
Pages: 767-80
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Quelle DE
Year: 1995
Journal: Cell
Title: Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.
Volume: 83
Issue: 6
Pages: 993-1000
Publication
First Author: Inoue K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.
Volume: 96
Issue: 7
Pages: 3993-8
Publication
First Author: Reef S
Year: 2006
Journal: Mol Cell
Title: A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death.
Volume: 22
Issue: 4
Pages: 463-75
Publication
First Author: Gressani KM
Year: 1998
Journal: Carcinogenesis
Title: Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene.
Volume: 19
Issue: 6
Pages: 1045-52
Publication
First Author: Soloff EV
Year: 1996
Journal: Gene
Title: The 5'-flanking region of the E1 alpha form of the murine p16INK4a (MTS1) gene.
Volume: 180
Issue: 1-2
Pages: 213-5
Publication
First Author: Zhang Y
Year: 2001
Journal: Cell Growth Differ
Title: Control of p53 ubiquitination and nuclear export by MDM2 and ARF.
Volume: 12
Issue: 4
Pages: 175-86
Publication
First Author: Greenberg RA
Year: 1999
Journal: Cell
Title: Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Volume: 97
Issue: 4
Pages: 515-25
Publication
First Author: Khoo CM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.
Volume: 104
Issue: 10
Pages: 3931-6
Publication
First Author: Huijbers IJ
Year: 2006
Journal: Cancer Res
Title: An inducible mouse model of melanoma expressing a defined tumor antigen.
Volume: 66
Issue: 6
Pages: 3278-86
Publication
First Author: Carbonneau CL
Year: 2012
Journal: Blood
Title: Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Volume: 119
Issue: 3
Pages: 717-26
Publication
First Author: Moore LM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas.
Volume: 106
Issue: 39
Pages: 16675-9
Publication  
First Author: Lv F
Year: 2020
Journal: Front Cell Dev Biol
Title: CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Volume: 8
Pages: 176
Publication
First Author: Oreff GL
Year: 2023
Journal: Sci Rep
Title: Immortalized murine tenocyte cells: a novel and innovative tool for tendon research.
Volume: 13
Issue: 1
Pages: 1566
Publication
First Author: Jeon HM
Year: 2008
Journal: Genes Dev
Title: Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling.
Volume: 22
Issue: 15
Pages: 2028-33
Publication
First Author: Recio JA
Year: 2002
Journal: Cancer Res
Title: Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis.
Volume: 62
Issue: 22
Pages: 6724-30
Publication
First Author: D'Amico M
Year: 2003
Journal: Cancer Res
Title: The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
Volume: 63
Issue: 12
Pages: 3395-402
Publication
First Author: Chin L
Year: 1999
Journal: Nature
Title: Essential role for oncogenic Ras in tumour maintenance.
Volume: 400
Issue: 6743
Pages: 468-72
Publication
First Author: Kozono D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.
Volume: 112
Issue: 30
Pages: E4055-64
Publication
First Author: Ackermann J
Year: 2005
Journal: Cancer Res
Title: Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background.
Volume: 65
Issue: 10
Pages: 4005-11
Publication
First Author: Morrison JP
Year: 2007
Journal: Toxicol Pathol
Title: N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice.
Volume: 35
Issue: 6
Pages: 780-7
Publication  
First Author: Kim YC
Year: 2009
Journal: BMC Dev Biol
Title: Wnt4 is not sufficient to induce lobuloalveolar mammary development.
Volume: 9
Pages: 55
Publication  
First Author: Hao J
Year: 2009
Journal: BMC Gastroenterol
Title: Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.
Volume: 9
Pages: 59
Publication
First Author: Tolleson WH
Year: 2005
Journal: Arch Ophthalmol
Title: Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice.
Volume: 123
Issue: 8
Pages: 1088-94
Publication
First Author: Aghi M
Year: 2008
Journal: Oncogene
Title: Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.
Volume: 27
Issue: 30
Pages: 4249-54
Publication
First Author: Tang Y
Year: 2005
Journal: Cancer Res
Title: In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging.
Volume: 65
Issue: 18
Pages: 8324-30
Publication
First Author: Lewis BC
Year: 2003
Journal: Genes Dev
Title: The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer.
Volume: 17
Issue: 24
Pages: 3127-38
Publication
First Author: Walker GJ
Year: 2011
Journal: J Invest Dermatol
Title: Superficial spreading-like melanoma in Arf(-/-)::Tyr-Nras(Q61K)::K14-Kitl mice: keratinocyte Kit ligand expression sufficient to "translocate" melanomas from dermis to epidermis.
Volume: 131
Issue: 6
Pages: 1384-7
Publication
First Author: Tada T
Year: 2002
Journal: J Neurosci Methods
Title: A head holder for magnetic resonance imaging that allows the stereotaxic alignment of spontaneously occurring intracranial mouse tumors.
Volume: 116
Issue: 1
Pages: 1-7
Publication
First Author: Zhang Z
Year: 2004
Journal: Oncogene
Title: Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models.
Volume: 23
Issue: 21
Pages: 3841-50
Publication
First Author: Liu J
Year: 2012
Journal: PLoS One
Title: Induction of histiocytic sarcoma in mouse skeletal muscle.
Volume: 7
Issue: 8
Pages: e44044
Publication
First Author: Altomare DA
Year: 2011
Journal: PLoS One
Title: Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis.
Volume: 6
Issue: 4
Pages: e18828
Publication
First Author: Pantoja C
Year: 2001
Journal: Exp Gerontol
Title: Identification of the gene immediately downstream of the murine INK4a/ARF locus.
Volume: 36
Issue: 8
Pages: 1289-302
Publication
First Author: Boquoi A
Year: 2009
Journal: Cancer Prev Res (Phila)
Title: Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032.
Volume: 2
Issue: 9
Pages: 800-6
Publication
First Author: Lv F
Year: 2017
Journal: Biochem Biophys Res Commun
Title: p16 deficiency promotes nonalcoholic steatohepatitis via regulation of hepatic oxidative stress.
Volume: 486
Issue: 2
Pages: 264-269
Publication
First Author: Sundar IK
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Genetic Ablation of p16INK4a Does Not Protect against Cellular Senescence in Mouse Models of Chronic Obstructive Pulmonary Disease/Emphysema.
Volume: 59
Issue: 2
Pages: 189-199
Publication
First Author: Xu B
Year: 2015
Journal: Blood
Title: Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia.
Volume: 125
Issue: 2
Pages: 346-57
Publication
First Author: Orlow I
Year: 1999
Journal: Int J Oncol
Title: Involvement of the Ink4a gene (p16 and p19arf) in murine tumorigenesis.
Volume: 15
Issue: 1
Pages: 17-24
Publication  
First Author: Guijarro MV
Year: 2023
Journal: JCI Insight
Title: First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.
Volume: 8
Issue: 10
Publication
First Author: Sung YH
Year: 2005
Journal: Mech Ageing Dev
Title: Hematopoietic malignancies associated with increased Stat5 and Bcl-x(L) expressions in Ink4a/Arf-deficient mice.
Volume: 126
Issue: 6-7
Pages: 732-9
Publication
First Author: Price JD
Year: 2014
Journal: J Neurosci
Title: The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation.
Volume: 34
Issue: 37
Pages: 12560-7
Publication
First Author: Becher OJ
Year: 2010
Journal: Cancer Res
Title: Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.
Volume: 70
Issue: 6
Pages: 2548-57
Publication
First Author: Sharpless NE
Year: 2004
Journal: Oncogene
Title: The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.
Volume: 23
Issue: 2
Pages: 379-85
Publication
First Author: Rajbhandari N
Year: 2017
Journal: Cell Rep
Title: Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers.
Volume: 18
Issue: 9
Pages: 2243-2255
Publication
First Author: Lyustikman Y
Year: 2008
Journal: Neoplasia
Title: Constitutive activation of Raf-1 induces glioma formation in mice.
Volume: 10
Issue: 5
Pages: 501-10
Publication
First Author: Jin X
Year: 2011
Journal: Cancer Res
Title: EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction.
Volume: 71
Issue: 22
Pages: 7125-34
Publication
First Author: Schmid S
Year: 2024
Journal: Cell Rep
Title: ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
Volume: 43
Issue: 10
Pages: 114829
Publication
First Author: Mohankumar KM
Year: 2015
Journal: Nat Genet
Title: An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.
Volume: 47
Issue: 8
Pages: 878-87
Publication
First Author: Watson SS
Year: 2024
Journal: Cancer Cell
Title: Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence.
Volume: 42
Issue: 9
Pages: 1507-1527.e11
Publication
First Author: Jeong JH
Year: 2008
Journal: PLoS One
Title: BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
Volume: 3
Issue: 12
Pages: e3949
Publication
First Author: Yang C
Year: 2004
Journal: Am J Pathol
Title: The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer.
Volume: 164
Issue: 3
Pages: 1031-8
Publication
First Author: Shimizu T
Year: 2010
Journal: Oncogene
Title: c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.
Volume: 29
Issue: 42
Pages: 5687-99
Publication
First Author: Holland EC
Year: 2000
Journal: Toxicol Pathol
Title: A mouse model for glioma: biology, pathology, and therapeutic opportunities.
Volume: 28
Issue: 1
Pages: 171-7
Publication
First Author: Galanzha EI
Year: 2009
Journal: Cancer Res
Title: In vivo, noninvasive, label-free detection and eradication of circulating metastatic melanoma cells using two-color photoacoustic flow cytometry with a diode laser.
Volume: 69
Issue: 20
Pages: 7926-34
Publication
First Author: Johnson SM
Year: 2010
Journal: J Clin Invest
Title: Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition.
Volume: 120
Issue: 7
Pages: 2528-36
Publication
First Author: Sarkar-Agrawal P
Year: 2004
Journal: J Natl Cancer Inst
Title: Impaired processing of DNA photoproducts and ultraviolet hypermutability with loss of p16INK4a or p19ARF.
Volume: 96
Issue: 23
Pages: 1790-3
Publication
First Author: Latendresse JR
Year: 2007
Journal: Toxicol Pathol
Title: Two cases of uveal amelanotic melanoma in transgenic Tyr-HRAS+ Ink4a/Arf heterozygous mice.
Volume: 35
Issue: 6
Pages: 827-32
Publication
First Author: Gibson SL
Year: 2005
Journal: Cancer Biol Ther
Title: p16(Ink4a) inhibits histologic progression and angiogenic signaling in min colon tumors.
Volume: 4
Issue: 12
Pages: 1389-94
Publication
First Author: Lee DH
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: INK4a deletion results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury.
Volume: 302
Issue: 1
Pages: F183-91
Publication
First Author: Szulzewsky F
Year: 2020
Journal: Genes Dev
Title: Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Volume: 34
Issue: 15-16
Pages: 1051-1064
Publication
First Author: Roberts PJ
Year: 2012
Journal: Clin Cancer Res
Title: Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models.
Volume: 18
Issue: 19
Pages: 5290-303
Publication
First Author: Wang Y
Year: 2003
Journal: Cancer Res
Title: Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
Volume: 63
Issue: 15
Pages: 4389-95
Publication
First Author: Sachs Z
Year: 2004
Journal: J Virol
Title: p16(Ink4a) interferes with Abelson virus transformation by enhancing apoptosis.
Volume: 78
Issue: 7
Pages: 3304-11
Publication
First Author: Uhrbom L
Year: 2002
Journal: Cancer Res
Title: Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
Volume: 62
Issue: 19
Pages: 5551-8
Publication
First Author: Wolstein JM
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: INK4a knockout mice exhibit increased fibrosis under normal conditions and in response to unilateral ureteral obstruction.
Volume: 299
Issue: 6
Pages: F1486-95
Publication
First Author: Koutcher JA
Year: 2002
Journal: Neoplasia
Title: MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials.
Volume: 4
Issue: 6
Pages: 480-5
Publication
First Author: Sullivan JP
Year: 2010
Journal: Cancer Res
Title: Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
Volume: 70
Issue: 23
Pages: 9937-48
Publication
First Author: Sharpless NE
Year: 2001
Journal: Nature
Title: Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
Volume: 413
Issue: 6851
Pages: 86-91
Publication
First Author: Li M
Year: 2013
Journal: Leukemia
Title: Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations.
Volume: 27
Issue: 7
Pages: 1570-3
Publication
First Author: Molofsky AV
Year: 2006
Journal: Nature
Title: Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing.
Volume: 443
Issue: 7110
Pages: 448-52
Publication
First Author: Tyagi E
Year: 2017
Journal: Oncotarget
Title: Loss of p16(INK4A) stimulates aberrant mitochondrial biogenesis through a CDK4/Rb-independent pathway.
Volume: 8
Issue: 34
Pages: 55848-55862
Publication
First Author: Hayashi Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.
Volume: 113
Issue: 46
Pages: 13057-13062
Publication
First Author: Janzen V
Year: 2006
Journal: Nature
Title: Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a.
Volume: 443
Issue: 7110
Pages: 421-6