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Search results 301 to 326 out of 326 for Cpm

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Type Details Score
Publication
First Author: Tan F
Year: 2003
Journal: Biochem J
Title: Effect of mutation of two critical glutamic acid residues on the activity and stability of human carboxypeptidase M and characterization of its signal for glycosylphosphatidylinositol anchoring.
Volume: 370
Issue: Pt 2
Pages: 567-78
Publication
First Author: Deiteren K
Year: 2007
Journal: Biochim Biophys Acta
Title: The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over.
Volume: 1774
Issue: 2
Pages: 267-77
Publication
First Author: Marquez-Curtis L
Year: 2008
Journal: Stem Cells
Title: Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of stromal cell-derived factor-1alpha: another player in hematopoietic stem/progenitor cell mobilization?
Volume: 26
Issue: 5
Pages: 1211-20
Publication
First Author: Zhang X
Year: 2008
Journal: J Biol Chem
Title: Carboxypeptidase M and kinin B1 receptors interact to facilitate efficient b1 signaling from B2 agonists.
Volume: 283
Issue: 12
Pages: 7994-8004
Protein Domain
Type: Domain
Description: Carboxypeptidase M (CPM; MEROPS identifier M14.006; ) is an extracellular glycoprotein, bound to cell membranes via a glycosyl-phosphatidylinositol on the C terminus of the protein []. It specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins [, ]. The highest levels of CPM have been found in human lung and placenta, but significant amounts are present in kidney, blood vessels, intestine, brain, and peripheral nerves. CPM has also been found in soluble form in various body fluids, including amniotic fluid, seminal plasma and urine. Due to its wide distribution in a variety of tissues, it is believed that it plays an important role in the control of peptide hormones and growth factor activity on the cell surface and in the membrane-localized degradation of extracellular proteins. For example, it hydrolyses the C-terminal arginine of epidermal growth factor (EGF) resulting in des-Arg-EGF which binds to the EGF receptor (EGFR) with an equal or greater affinity than native EGF. CPM is a required processing enzyme that generates specific agonists for the B1 receptor [, ].This entry represents the carboxypeptidase (N-terminal) domain of carboxypeptidase M.
Publication
First Author: Daillère R
Year: 2016
Journal: Immunity
Title: Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects.
Volume: 45
Issue: 4
Pages: 931-943
Publication
First Author: Roberti MP
Year: 2020
Journal: Nat Med
Title: Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer.
Volume: 26
Issue: 6
Pages: 919-931
Publication    
First Author: Comai G
Year: 2019
Journal: Elife
Title: A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle.
Volume: 8
Publication  
First Author: Adachi N
Year: 2020
Journal: Development
Title: Cardiopharyngeal mesoderm origins of musculoskeletal and connective tissues in the mammalian pharynx.
Volume: 147
Issue: 3
Publication
First Author: Webb ER
Year: 2022
Journal: iScience
Title: Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma.
Volume: 25
Issue: 9
Pages: 104995
Publication    
First Author: Baker SA
Year: 2021
Journal: Elife
Title: Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon.
Volume: 10
Publication
First Author: Frishberg A
Year: 2019
Journal: Nat Methods
Title: Cell composition analysis of bulk genomics using single-cell data.
Volume: 16
Issue: 4
Pages: 327-332
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Soltys J
Year: 2002
Journal: J Immunol
Title: Functional IL-10 deficiency in the lung of cystic fibrosis (cftr(-/-)) and IL-10 knockout mice causes increased expression and function of B7 costimulatory molecules on alveolar macrophages.
Volume: 168
Issue: 4
Pages: 1903-10
Publication  
First Author: Dumas CE
Year: 2024
Journal: Development
Title: Retinoic acid signalling regulates branchiomeric neck muscle development at the head/trunk interface.
Volume: 151
Issue: 16
Publication    
First Author: Maruyama K
Year: 2022
Journal: Elife
Title: The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse.
Volume: 11
Publication
First Author: Vidović D
Year: 1985
Journal: J Immunol
Title: Recessive T cell response to poly (Glu50Tyr50) possibly caused by self tolerance.
Volume: 134
Issue: 6
Pages: 3563-8
Publication
First Author: Ferreras L
Year: 1994
Journal: Int J Obes Relat Metab Disord
Title: Early decrease in GLUT4 protein levels in brown adipose tissue of New Zealand obese mice.
Volume: 18
Issue: 11
Pages: 760-5
Publication
First Author: Fabres-Machado U
Year: 1995
Journal: Braz J Med Biol Res
Title: The effect of adipose cell size on the measurement of GLUT 4 in white adipose tissue of obese mice.
Volume: 28
Issue: 3
Pages: 369-76
Publication
First Author: Mikkelsen HB
Year: 1998
Journal: Neurogastroenterol Motil
Title: Action potential generation, Kit receptor immunohistochemistry and morphology of steel-Dickie (Sl/Sld) mutant mouse small intestine.
Volume: 10
Issue: 1
Pages: 11-26
Publication
First Author: Wang CH
Year: 2005
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury.
Volume: 289
Issue: 2
Pages: R299-304
Publication
First Author: Nathan E
Year: 2008
Journal: Development
Title: The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development.
Volume: 135
Issue: 4
Pages: 647-57
Publication      
First Author: Stathopoulou A
Year: 2023
Journal: Cardiovasc Res
Title: CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression.
Publication
First Author: O'Brien DA
Year: 1993
Journal: Biol Reprod
Title: Mouse Sertoli cells secrete mannose 6-phosphate containing glycoproteins that are endocytosed by spermatogenic cells.
Volume: 49
Issue: 5
Pages: 1055-65
Publication
First Author: Schwartz RH
Year: 1975
Journal: J Immunol
Title: T lymphocyte-enriched murine peritoneal exudate cells. I. A reliable assay for antigen-induced T lymphocyte proliferation.
Volume: 115
Issue: 5
Pages: 1330-8
Publication
First Author: Gough DB
Year: 1992
Journal: Arch Surg
Title: Impaired cell-mediated immunity in experimental abdominal sepsis and the effect of interleukin 2.
Volume: 127
Issue: 7
Pages: 859-63