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Search results 301 to 400 out of 410 for Crb1

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Type Details Score
Publication
28739342 | J:248968
First Author: Feng L
Year: 2017
Journal: Am J Pathol
Title: A Proinflammatory Function of Toll-Like Receptor 2 in the Retinal Pigment Epithelium as a Novel Target for Reducing Choroidal Neovascularization in Age-Related Macular Degeneration.
Volume: 187
Issue: 10
Pages: 2208-2221
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Publication
26216965 | J:226512
First Author: Datta P
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Volume: 112
Issue: 32
Pages: E4400-9
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Publication
25188381 | J:221530
First Author: Hasegawa E
Year: 2014
Journal: PLoS One
Title: Characterization of a spontaneous retinal neovascular mouse model.
Volume: 9
Issue: 9
Pages: e106507
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Publication
32694816 | J:269980
First Author: Enríquez JA
Year: 2019
Journal: Nat Metab
Title: Mind your mouse strain.
Volume: 1
Issue: 1
Pages: 5-7
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Publication
39138242 | J:353848
First Author: Seyed-Razavi Y
Year: 2024
Journal: Sci Rep
Title: JR5558 mice are a reliable model to investigate subretinal fibrosis.
Volume: 14
Issue: 1
Pages: 18752
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Publication
- | J:353326
     
First Author: Chang B
Year: 2024
Journal: MGI Direct Data Submission
Title: The D2.Cg-Crb1em2Boc/Boc Strain.
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Publication
28270521 | J:246071
First Author: Chen Q
Year: 2017
Journal: Diabetes
Title: Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα.
Volume: 66
Issue: 6
Pages: 1671-1682
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Publication
29571629 | J:281416
 
First Author: Liu YH
Year: 2018
Journal: Exp Eye Res
Title: Partial retinal photoreceptor loss in a transgenic mouse model associated with reduced levels of interphotoreceptor retinol binding protein (IRBP, RBP3).
Volume: 172
Pages: 54-65
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Publication
25793273 | J:233438
First Author: Hippert C
Year: 2015
Journal: PLoS One
Title: Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific.
Volume: 10
Issue: 3
Pages: e0120415
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Publication
26978024 | J:237977
First Author: Ji X
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ.
Volume: 57
Issue: 3
Pages: 877-88
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Publication
25015357 | J:230135
First Author: Flynn E
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence and photoreceptor cell rosettes in mouse models.
Volume: 55
Issue: 9
Pages: 5643-52
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Publication
23677863 | J:280327
First Author: Ramkumar HL
Year: 2013
Journal: J Nutr
Title: Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background.
Volume: 143
Issue: 7
Pages: 1129-35
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Publication
24709779 | J:210964
First Author: Wang Y
Year: 2014
Journal: Lab Invest
Title: Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration.
Volume: 94
Issue: 6
Pages: 674-82
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Publication
23074204 | J:214216
First Author: Vessey KA
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Ccl2/Cx3cr1 knockout mice have inner retinal dysfunction but are not an accelerated model of AMD.
Volume: 53
Issue: 12
Pages: 7833-46
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Publication
38267952 | J:350731
First Author: Rivera-García LG
Year: 2024
Journal: J Inflamm (Lond)
Title: Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain.
Volume: 21
Issue: 1
Pages: 2
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Publication
36724077 | J:355005
First Author: Tomlinson KL
Year: 2023
Journal: Cell Rep
Title: Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst.
Volume: 42
Issue: 2
Pages: 112064
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Publication
35197297 | J:321909
 
First Author: Palko SI
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Compartmentalized citrullination in Muller glial endfeet during retinal degeneration.
Volume: 119
Issue: 9
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Publication
24780906 | J:215272
First Author: Ardeljan D
Year: 2014
Journal: PLoS One
Title: Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.
Volume: 9
Issue: 4
Pages: e95900
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Publication
27521426 | J:246812
First Author: Campbell CI
Year: 2016
Journal: J Cell Sci
Title: The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.
Volume: 129
Issue: 18
Pages: 3396-411
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Publication
23248312 | J:192521
First Author: Barber AC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Repair of the degenerate retina by photoreceptor transplantation.
Volume: 110
Issue: 1
Pages: 354-9
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Publication
33479377 | J:300263
First Author: Beryozkin A
Year: 2021
Journal: Sci Rep
Title: A new mouse model for retinal degeneration due to Fam161a deficiency.
Volume: 11
Issue: 1
Pages: 2030
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Publication
23221340 | J:194158
First Author: Zhang N
Year: 2013
Journal: J Clin Invest
Title: Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.
Volume: 123
Issue: 1
Pages: 121-37
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Publication
24639355 | J:210001
First Author: Kohno H
Year: 2014
Journal: J Immunol
Title: CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Volume: 192
Issue: 8
Pages: 3816-27
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Publication
23341467 | J:196891
First Author: Chen Y
Year: 2013
Journal: J Biol Chem
Title: Autophagy protects the retina from light-induced degeneration.
Volume: 288
Issue: 11
Pages: 7506-18
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Publication
25034607 | J:230121
First Author: Samardzija M
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: A mouse model for studying cone photoreceptor pathologies.
Volume: 55
Issue: 8
Pages: 5304-13
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Publication
32265302 | J:292103
First Author: Liao C
Year: 2020
Journal: J Biol Chem
Title: Activation of JNK signaling promotes all-trans-retinal-induced photoreceptor apoptosis in mice.
Volume: 295
Issue: 20
Pages: 6958-6971
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Publication
17920587 | J:296096
First Author: Gosens I
Year: 2007
Journal: Exp Cell Res
Title: FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.
Volume: 313
Issue: 19
Pages: 3959-70
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Publication
29155075 | J:260419
 
First Author: Jiang X
Year: 2018
Journal: Gene Expr Patterns
Title: Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development.
Volume: 27
Pages: 93-98
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Publication
32277911 | J:288504
First Author: Zhou C
Year: 2020
Journal: Immunity
Title: Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.
Volume: 52
Issue: 5
Pages: 767-781.e6
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Publication
11853768 | J:75095
First Author: Chang B
Year: 2002
Journal: Vision Res
Title: Retinal degeneration mutants in the mouse.
Volume: 42
Issue: 4
Pages: 517-25
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Publication
25636444 | J:220858
First Author: Kim JY
Year: 2015
Journal: Gene Expr Patterns
Title: Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye.
Volume: 17
Issue: 1
Pages: 31-7
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Publication
26496195 | J:227336
First Author: Ramkumar N
Year: 2015
Journal: PLoS Genet
Title: Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.
Volume: 11
Issue: 10
Pages: e1005551
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Publication
27701636 | J:254591
First Author: Alldredge A
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Loss of Axin2 Causes Ocular Defects During Mouse Eye Development.
Volume: 57
Issue: 13
Pages: 5253-5262
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Publication
17507402 | J:122548
First Author: Lee JD
Year: 2007
Journal: Development
Title: The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo.
Volume: 134
Issue: 11
Pages: 2007-16
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Publication
27870829 | J:238551
First Author: Ramkumar N
Year: 2016
Journal: Nat Cell Biol
Title: Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation.
Volume: 18
Issue: 12
Pages: 1281-1291
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Publication
26802325 | J:236353
 
First Author: Dudok JJ
Year: 2016
Journal: Neurosci Res
Title: Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.
Volume: 108
Pages: 12-23
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Publication
33073849 | J:298840
First Author: Sterling N
Year: 2020
Journal: Hum Mol Genet
Title: De novo variants in MPP5 cause global developmental delay and behavioral changes.
Volume: 29
Issue: 20
Pages: 3388-3401
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Publication
24164893 | J:206750
First Author: Whiteman EL
Year: 2014
Journal: Mol Cell Biol
Title: Crumbs3 is essential for proper epithelial development and viability.
Volume: 34
Issue: 1
Pages: 43-56
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Publication
31586559 | J:283394
First Author: Hughes LJ
Year: 2020
Journal: Dev Biol
Title: Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Volume: 457
Issue: 1
Pages: 150-162
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Publication
- | J:82238
     
First Author: JAX Neuroscience Mutagenesis Facility
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from JAX NMF ENU Mutagenesis Program
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Publication
25742799 | J:220469
First Author: Grego-Bessa J
Year: 2015
Journal: Development
Title: Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.
Volume: 142
Issue: 7
Pages: 1305-14
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Publication
27616714 | J:237224
First Author: Kim JY
Year: 2016
Journal: Dev Biol
Title: Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.
Volume: 419
Issue: 2
Pages: 336-347
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Publication
16332269 | J:156373
First Author: Chang B
Year: 2005
Journal: Vis Neurosci
Title: Mouse models of ocular diseases.
Volume: 22
Issue: 5
Pages: 587-93
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Publication
21052544 | J:166679
 
First Author: Won J
Year: 2011
Journal: J Ophthalmol
Title: Mouse model resources for vision research.
Volume: 2011
Pages: 391384
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Publication
16110338 | J:107820
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
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Publication
16107646 | J:100324
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
15914641 | J:248447
First Author: Kantardzhieva A
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: MPP5 recruits MPP4 to the CRB1 complex in photoreceptors.
Volume: 46
Issue: 6
Pages: 2192-201
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Allele
Crb1<tm1c(EUCOMM)Hmgu> | MGI:6363347
Name: crumbs family member 1, photoreceptor morphogenesis associated; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
37541258 | J:356212
     
First Author: Buck TM
Year: 2023
Journal: Stem Cell Reports
Title: CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids.
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Allele
Crb1<em1Smoc> | MGI:7289137
Name: crumbs family member 1, photoreceptor morphogenesis associated; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Crb1<tm1Wij> | MGI:3052072
Name: crumbs family member 1, photoreceptor morphogenesis associated; targeted mutation 1, Jan Wijnholds
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Strain
MGI:6428481 | C57BL/6JSmoc-Crb1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Crb1/Crb1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0110358 | retinitis pigmentosa 12
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Allele
Crb1<rd8> | MGI:2676366
 
Name: crumbs family member 1, photoreceptor morphogenesis associated; retinal degeneration 8
Allele Type: Spontaneous
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Genotype
Genotype
Symbol: Crb1/Crb1
Background: STOCK Crb1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Crb1/Crb1 Crb2/Crb2 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Crb1/Crb1<+> Crb2/Crb2 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL
Zygosity: cn
Has Mutant Allele: true
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DO Term
DOID:0110079 | Leber congenital amaurosis 8
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DO Term
DOID:0111541 | pigmented paravenous chorioretinal atrophy
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Allele
Kif23<tm1.1Igo> | MGI:7522151
Name: kinesin family member 23; targeted mutation 1.1, Irina Golovleva
Allele Type: Targeted
Attribute String: Humanized sequence
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Publication
32818800 | J:321429
 
First Author: Vikberg AL
Year: 2020
Journal: Blood Cells Mol Dis
Title: Differential tissue specific expression of Kif23 alternative transcripts in mice with the human mutation causing congenital dyserythropoietic anemia type III.
Volume: 85
Pages: 102483
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Genotype
Genotype
Symbol: Kif23/Kif23
Background: involves: C57BL/6 * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kif23/Kif23<+>
Background: involves: C57BL/6 * C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
GSE239456 | mRNA transcript levels in E15.5, E17.5 and P1 Crb1KOCrb2deltaRPC against Crb1KO neuroretina, and in E15.5 Crb1KOCrb2deltaRPC against wild type neuroretina
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
21371776 | -
First Author: Dudak A
Year: 2011
Journal: Eur J Cell Biol
Title: Membrane palmitoylated proteins regulate trafficking and processing of nectins.
Volume: 90
Issue: 5
Pages: 365-75
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Protein Domain
IPR035604 | MPP3_SH3
Type: Domain
Description: This entry represents the SH3 domain of MPP3, which is a scaffolding protein that colocalizes with MPP5 and CRB1 at the subapical region adjacent to adherens junctions and may function in photoreceptor polarity. It interacts with some nectins and regulates their trafficking and processing. Nectins are cell-cell adhesion proteins involved in the establishment apical-basal polarity at cell adhesion sites []. MPP3 belongs to the membrane-associated guanylate kinase (MAGUK) p55 subfamily. The membrane-associated guanylate kinase (MAGUK) p55 subfamily (also known as MPP subfamily) members include the Drosophila Stardust protein and its vertebrate homologues, MPP1-7. They contain the core of three domains characteristic of MAGUK (membrane-associated guanylate kinase) proteins: PDZ, SH3, and guanylate kinase (GuK). In addition, they also contain the Hook (Protein 4.1 Binding) motif in between the SH3 and GuK domains []. MPP2-7 have two additional L27 domains at their N terminus. The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain [].
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Publication
16519681 | J:333179
First Author: Kantardzhieva A
Year: 2006
Journal: FEBS J
Title: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane.
Volume: 273
Issue: 6
Pages: 1152-65
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Publication
23893895 | J:199562
First Author: Dudok JJ
Year: 2013
Journal: Glia
Title: MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells.
Volume: 61
Issue: 10
Pages: 1629-44
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