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Search results 301 to 400 out of 418 for Crem

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Type Details Score
Publication  
First Author: Yoshida N
Year: 2016
Journal: Nat Commun
Title: ICER is requisite for Th17 differentiation.
Volume: 7
Pages: 12993
Publication
First Author: Li P
Year: 2021
Journal: Nat Immunol
Title: Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity.
Volume: 22
Issue: 9
Pages: 1107-1117
Publication
First Author: Vaeth M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1).
Volume: 108
Issue: 6
Pages: 2480-5
Publication  
First Author: Umeda M
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-β1.
Volume: 118
Issue: 18
Publication
First Author: Stock A
Year: 2011
Journal: J Exp Med
Title: Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans.
Volume: 208
Issue: 4
Pages: 761-73
Publication      
First Author: Shawlot W
Year: 2015
Journal: Genesis
Title: Rfx2 is required for spermatogenesis in the mouse.
Publication
First Author: Koga T
Year: 2014
Journal: J Clin Invest
Title: CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance.
Volume: 124
Issue: 5
Pages: 2234-45
Publication
First Author: Ogi T
Year: 2001
Journal: Genes Cells
Title: Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription.
Volume: 6
Issue: 11
Pages: 943-53
Publication
First Author: Parlato R
Year: 2007
Journal: Development
Title: Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis.
Volume: 134
Issue: 9
Pages: 1663-70
Publication
First Author: Grootegoed JA
Year: 1998
Journal: Mol Cell Endocrinol
Title: Knockout mouse model and gametogenic failure.
Volume: 145
Issue: 1-2
Pages: 161-6
Publication
First Author: Lonze BE
Year: 2002
Journal: Neuron
Title: Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.
Volume: 34
Issue: 3
Pages: 371-85
Publication
First Author: Rabionet M
Year: 2008
Journal: J Biol Chem
Title: Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3.
Volume: 283
Issue: 19
Pages: 13357-69
Publication
First Author: Mantamadiotis T
Year: 2006
Journal: Mol Endocrinol
Title: Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice.
Volume: 20
Issue: 1
Pages: 204-11
Publication
First Author: Aguado F
Year: 2009
Journal: J Neurosci
Title: The CREB/CREM transcription factors negatively regulate early synaptogenesis and spontaneous network activity.
Volume: 29
Issue: 2
Pages: 328-33
Publication
First Author: Chen AE
Year: 2005
Journal: Nature
Title: Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins.
Volume: 433
Issue: 7023
Pages: 317-22
Publication
First Author: Antony N
Year: 2013
Journal: PLoS One
Title: cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells.
Volume: 8
Issue: 4
Pages: e59763
Publication
First Author: Baker MD
Year: 2014
Journal: Reproduction
Title: The small GTPase Rheb is required for spermatogenesis but not oogenesis.
Volume: 147
Issue: 5
Pages: 615-25
Publication  
First Author: Vazquez-Chona FR
Year: 2005
Journal: Mol Vis
Title: Genetic networks controlling retinal injury.
Volume: 11
Pages: 958-70
Publication
First Author: Vourekas A
Year: 2015
Journal: Genes Dev
Title: The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.
Volume: 29
Issue: 6
Pages: 617-29
Publication
First Author: Murphy WJ
Year: 2001
Journal: Nature
Title: Molecular phylogenetics and the origins of placental mammals.
Volume: 409
Issue: 6820
Pages: 614-8
Publication
First Author: Shi X
Year: 2015
Journal: J Biol Chem
Title: The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.
Volume: 290
Issue: 15
Pages: 9614-25
Publication
First Author: Wu RC
Year: 2015
Journal: Mol Endocrinol
Title: Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.
Volume: 29
Issue: 9
Pages: 1334-46
Publication
First Author: Pandey RR
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.
Volume: 110
Issue: 41
Pages: 16492-7
Publication
First Author: Urano A
Year: 2005
Journal: Mol Cell Biol
Title: Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.
Volume: 25
Issue: 15
Pages: 6834-45
Publication
First Author: Kuramochi-Miyagawa S
Year: 2004
Journal: Development
Title: Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.
Volume: 131
Issue: 4
Pages: 839-49
Publication  
First Author: Gustafson EA
Year: 2020
Journal: Mol Cell Biol
Title: ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis.
Volume: 40
Issue: 7
Publication
First Author: De Castro SCP
Year: 2018
Journal: Hum Mol Genet
Title: Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice.
Volume: 27
Issue: 24
Pages: 4218-4230
Publication
First Author: Díaz-Ruiz C
Year: 2008
Journal: Mol Cell Neurosci
Title: Regulation of neural migration by the CREB/CREM transcription factors and altered Dab1 levels in CREB/CREM mutants.
Volume: 39
Issue: 4
Pages: 519-28
Publication
First Author: Bird AD
Year: 2011
Journal: PLoS One
Title: cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development.
Volume: 6
Issue: 3
Pages: e17843
Publication  
First Author: Barbagallo F
Year: 2020
Journal: Int J Mol Sci
Title: PDE2A Is Indispensable for Mouse Liver Development and Hematopoiesis.
Volume: 21
Issue: 8
Publication
First Author: Herdegen T
Year: 1998
Journal: Brain Res Brain Res Rev
Title: Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins.
Volume: 28
Issue: 3
Pages: 370-490
Publication
First Author: Yabuta Y
Year: 2011
Journal: J Cell Biol
Title: TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.
Volume: 192
Issue: 5
Pages: 781-95
Publication
First Author: Assenza MR
Year: 2018
Journal: Cardiovasc Res
Title: Critical role of phosphodiesterase 2A in mouse congenital heart defects.
Volume: 114
Issue: 6
Pages: 830-845
Publication
First Author: Ho UY
Year: 2021
Journal: Commun Biol
Title: WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis.
Volume: 4
Issue: 1
Pages: 645
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Experiment
Series Id: GSE29593
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment
Series Id: GSE29592
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Palermo I
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Cloning and expression of activator of CREM in testis in human testicular tissue.
Volume: 283
Issue: 2
Pages: 406-11
Publication
First Author: Uyttersprot N
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Dog CREM transcription factors: cloning, tissue distribution, and identification of new isoforms.
Volume: 237
Issue: 1
Pages: 74-8
Publication
First Author: Fimia GM
Year: 2001
Journal: Mol Cell Endocrinol
Title: Transcriptional cascades during spermatogenesis: pivotal role of CREM and ACT.
Volume: 179
Issue: 1-2
Pages: 17-23
Protein
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
Allele
Name: cAMP responsive element modulator; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Fimia GM
Year: 2000
Journal: Mol Cell Biol
Title: A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM.
Volume: 20
Issue: 22
Pages: 8613-22
Publication
First Author: Hailemariam K
Year: 2010
Journal: J Cell Sci
Title: Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress.
Volume: 123
Issue: Pt 22
Pages: 3863-71
Publication
First Author: Jin XL
Year: 2014
Journal: Reproduction
Title: The regulation of the expression and activation of the essential ATF1 transcription factor in the mouse preimplantation embryo.
Volume: 148
Issue: 2
Pages: 147-57
Protein Domain
Type: Family
Description: ATF1, CREB, and CREM constitute a subfamily of the basic leucine zipper transcription factors, and they activate gene expression by binding as homo- or heterodimers to the cAMP response elements (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'). ATF1 (activating transcription factor 1) plays important roles in cell survival and proliferation [, ]. It is required for the development of preimplantation embryos [].
Publication  
First Author: Lardenois A
Year: 2009
Journal: Reprod Biol Endocrinol
Title: Fhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression.
Volume: 7
Pages: 133
Protein Domain
Type: Domain
Description: This entry represents the second LIM domain of Four and a half LIM domains protein 5 (FHL5, also known as ACT), which belongs to the CREB/CREM family of transcription factors. FHL5 is highly expressed in male germ cells and is required for post-meiotic gene expression. It associates with CREM and confers a powerful transcriptional activation function []. Activation by CREB has known to occur upon phosphorylation at an essential regulatory site and the subsequent interaction with the ubiquitous coactivator CREB-binding protein (CBP). However, the activation by FHL5 is independent of phosphorylation and CBP association. It represents a new route for transcriptional activation by CREM and CREB [, ].LIM domains are 50-60 amino acids in size and share two characteristic zinc finger motifs. The two zinc fingers contain eight conserved residues, mostly cysteines and histidines, which coordinately bind to two zinc atoms. LIM domains function as adaptors or scaffolds to support the assembly of multimeric protein complexes [, , ].
Publication
First Author: Ruppert S
Year: 1992
Journal: EMBO J
Title: Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes.
Volume: 11
Issue: 4
Pages: 1503-12
Publication
First Author: Baumann S
Year: 2004
Journal: Eur J Immunol
Title: CREB function is required for normal thymic cellularity and post-irradiation recovery.
Volume: 34
Issue: 7
Pages: 1961-71
Publication
First Author: Martianov I
Year: 2001
Journal: Mol Cell
Title: Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene.
Volume: 7
Issue: 3
Pages: 509-15
Publication
First Author: Kotaja N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene.
Volume: 101
Issue: 29
Pages: 10620-5
Publication
First Author: Cheatham L
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Structural and functional analysis of pp70S6k.
Volume: 92
Issue: 25
Pages: 11696-700
Publication
First Author: Maine CJ
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection.
Volume: 113
Issue: 46
Pages: E7231-E7239
Publication
First Author: Dawid IB
Year: 1998
Journal: Trends Genet
Title: LIM domains: multiple roles as adapters and functional modifiers in protein interactions.
Volume: 14
Issue: 4
Pages: 156-62
Publication
First Author: Zheng Q
Year: 2007
Journal: Biol Cell
Title: The diverse biofunctions of LIM domain proteins: determined by subcellular localization and protein-protein interaction.
Volume: 99
Issue: 9
Pages: 489-502
Publication
First Author: Toshima J
Year: 1998
Journal: Gene
Title: Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene.
Volume: 206
Issue: 2
Pages: 237-45
Publication
First Author: Hummler E
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.
Volume: 91
Issue: 12
Pages: 5647-51
Publication  
First Author: Vogt MA
Year: 2014
Journal: Front Behav Neurosci
Title: Inducible forebrain-specific ablation of the transcription factor Creb during adulthood induces anxiety but no spatial/contextual learning deficits.
Volume: 8
Pages: 407
Publication
First Author: Casanova E
Year: 2002
Journal: Genesis
Title: ER-based double iCre fusion protein allows partial recombination in forebrain.
Volume: 34
Issue: 3
Pages: 208-14
Publication
First Author: Grozdanov PN
Year: 2016
Journal: Biol Reprod
Title: TauCstF-64 Mediates Correct mRNA Polyadenylation and Splicing of Activator and Repressor Isoforms of the Cyclic AMP-Responsive Element Modulator (CREM) in Mouse Testis.
Volume: 94
Issue: 2
Pages: 34
Publication
First Author: Chen HY
Year: 2013
Journal: Nucleic Acids Res
Title: DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.
Volume: 41
Issue: 21
Pages: 9858-69