| Type |
Details |
Score |
| Publication |
| First Author: |
Yang Z |
| Year: |
1997 |
| Journal: |
Genomics |
| Title: |
Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse. |
| Volume: |
45 |
| Issue: |
1 |
| Pages: |
123-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walther C |
| Year: |
1991 |
| Journal: |
Genomics |
| Title: |
Pax: a murine multigene family of paired box-containing genes. |
| Volume: |
11 |
| Issue: |
2 |
| Pages: |
424-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Colombo MP |
| Year: |
1992 |
| Journal: |
Mamm Genome |
| Title: |
Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16. |
| Volume: |
2 |
| Issue: |
2 |
| Pages: |
130-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Copeland NG |
| Year: |
1995 |
| Journal: |
Genomics |
| Title: |
Distribution of the mammalian Stat gene family in mouse chromosomes. |
| Volume: |
29 |
| Issue: |
1 |
| Pages: |
225-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Y |
| Year: |
1996 |
| Journal: |
J Biol Chem |
| Title: |
A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. |
| Volume: |
271 |
| Issue: |
8 |
| Pages: |
4468-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farmer MA |
| Year: |
2001 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. |
| Volume: |
98 |
| Issue: |
24 |
| Pages: |
13820-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishikii H |
| Year: |
2016 |
| Journal: |
Blood |
| Title: |
DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease. |
| Volume: |
128 |
| Issue: |
24 |
| Pages: |
2846-2858 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Le Roy H |
| Year: |
1992 |
| Journal: |
Mamm Genome |
| Title: |
A set of anonymous DNA clones as markers for mouse gene mapping. |
| Volume: |
3 |
| Issue: |
4 |
| Pages: |
244-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ko MS |
| Year: |
1994 |
| Journal: |
Mamm Genome |
| Title: |
Genetic mapping of 40 cDNA clones on the mouse genome by PCR. |
| Volume: |
5 |
| Issue: |
6 |
| Pages: |
349-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hasson T |
| Year: |
1996 |
| Journal: |
Genomics |
| Title: |
Mapping of unconventional myosins in mouse and human. |
| Volume: |
36 |
| Issue: |
3 |
| Pages: |
431-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rowe LB |
| Year: |
1994 |
| Journal: |
Mamm Genome |
| Title: |
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. |
| Volume: |
5 |
| Issue: |
5 |
| Pages: |
253-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
| Year: |
1993 |
|
| Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
Ctla4 expression QTL; C57BL/6 |
| Allele Type: |
QTL |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kwek SS |
| Year: |
2012 |
| Journal: |
Nat Rev Cancer |
| Title: |
Unmasking the immune recognition of prostate cancer with CTLA4 blockade. |
| Volume: |
12 |
| Issue: |
4 |
| Pages: |
289-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fu M |
| Year: |
2024 |
| Journal: |
Cancer Cell |
| Title: |
Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade. |
| Volume: |
42 |
| Issue: |
11 |
| Pages: |
1882-1897.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burr JS |
| Year: |
2001 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
CD28 and CTLA4 coordinately regulate airway inflammatory cell recruitment and T-helper cell differentiation after inhaled allergen. |
| Volume: |
24 |
| Issue: |
5 |
| Pages: |
563-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li F |
| Year: |
2021 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
TFH cells depend on Tcf1-intrinsic HDAC activity to suppress CTLA4 and guard B-cell help function. |
| Volume: |
118 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shin JH |
| Year: |
2012 |
| Journal: |
Blood |
| Title: |
Positive conversion of negative signaling of CTLA4 potentiates antitumor efficacy of adoptive T-cell therapy in murine tumor models. |
| Volume: |
119 |
| Issue: |
24 |
| Pages: |
5678-87 |
|
•
•
•
•
•
|
| Pathway |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singh TP |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder. |
| Volume: |
184 |
| Issue: |
12 |
| Pages: |
7257-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin H |
| Year: |
1998 |
| Journal: |
J Exp Med |
| Title: |
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. |
| Volume: |
188 |
| Issue: |
1 |
| Pages: |
199-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nawaf MG |
| Year: |
2017 |
| Journal: |
J Immunol |
| Title: |
Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity. |
| Volume: |
199 |
| Issue: |
3 |
| Pages: |
974-981 |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 3, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 4, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
insulin dependent diabetes susceptibility 3; NOD |
| Allele Type: |
QTL |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD28 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; targeted mutation 1, Yang Liu |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Idd3/? |
| Background: |
involves: C57BL/10 * NOD |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, QTL |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nguyen CQ |
| Year: |
2011 |
| Journal: |
Lab Invest |
| Title: |
IL17: potential therapeutic target in Sjögren's syndrome using adenovirus-mediated gene transfer. |
| Volume: |
91 |
| Issue: |
1 |
| Pages: |
54-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nguyen CQ |
| Year: |
2009 |
| Journal: |
Exp Eye Res |
| Title: |
Differential gene expressions in the lacrimal gland during development and onset of keratoconjunctivitis sicca in Sjögren's syndrome (SJS)-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. |
| Volume: |
88 |
| Issue: |
3 |
| Pages: |
398-409 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lundholm M |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Variation in the Cd3 zeta (Cd247) gene correlates with altered T cell activation and is associated with autoimmune diabetes. |
| Volume: |
184 |
| Issue: |
10 |
| Pages: |
5537-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Encinas JA |
| Year: |
1999 |
| Journal: |
Nat Genet |
| Title: |
QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2. |
| Volume: |
21 |
| Issue: |
2 |
| Pages: |
158-60 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; mutation 1, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ctla4/Ctla4 |
| Background: |
B6.129-Ctla4 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Idd3/Idd3 Idd5/Idd5 |
| Background: |
B6.NOD-Idd5 Idd3 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
306
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Podolin PL |
| Year: |
2000 |
| Journal: |
Cytokine |
| Title: |
Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type 1 diabetes gene? |
| Volume: |
12 |
| Issue: |
5 |
| Pages: |
477-82 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
chemically induced mutation, coisogenic, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation, endonuclease-mediated mutation |
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•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Idd10/Idd10 Idd3/Idd3 |
| Background: |
B6.NOD-Idd3 Idd10 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ctla4/Ctla4 |
| Background: |
C57BL/6J-Ctla4 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cornall RJ |
| Year: |
1993 |
| Journal: |
Clin Sci (Lond) |
| Title: |
Genetics of a multifactorial disease: autoimmune type 1 diabetes mellitus. |
| Volume: |
84 |
| Issue: |
3 |
| Pages: |
257-62 |
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