Type |
Details |
Score |
Publication |
First Author: |
Metzis V |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Patched1 is required in neural crest cells for the prevention of orofacial clefts. |
Volume: |
22 |
Issue: |
24 |
Pages: |
5026-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan X |
Year: |
2008 |
Journal: |
Hepatology |
Title: |
Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development. |
Volume: |
47 |
Issue: |
5 |
Pages: |
1667-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marciano DK |
Year: |
2011 |
Journal: |
Development |
Title: |
p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. |
Volume: |
138 |
Issue: |
10 |
Pages: |
2099-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pieters T |
Year: |
2020 |
Journal: |
BMC Dev Biol |
Title: |
Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice. |
Volume: |
20 |
Issue: |
1 |
Pages: |
17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tunggal JA |
Year: |
2005 |
Journal: |
EMBO J |
Title: |
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. |
Volume: |
24 |
Issue: |
6 |
Pages: |
1146-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Darrigrand JF |
Year: |
2024 |
Journal: |
Dev Cell |
Title: |
Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. |
Volume: |
59 |
Issue: |
3 |
Pages: |
326-338.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weis VG |
Year: |
2016 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. |
Volume: |
2 |
Issue: |
2 |
Pages: |
131-157 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rakotomamonjy J |
Year: |
2017 |
Journal: |
Neural Dev |
Title: |
Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia. |
Volume: |
12 |
Issue: |
1 |
Pages: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo D |
Year: |
2020 |
Journal: |
Development |
Title: |
Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition. |
Volume: |
147 |
Issue: |
22 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Alvarez JI |
Year: |
2011 |
Journal: |
Science |
Title: |
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. |
Volume: |
334 |
Issue: |
6063 |
Pages: |
1727-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nelson DA |
Year: |
2013 |
Journal: |
Biol Open |
Title: |
Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. |
Volume: |
2 |
Issue: |
5 |
Pages: |
439-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alves CH |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. |
Volume: |
22 |
Issue: |
1 |
Pages: |
35-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suriben R |
Year: |
2009 |
Journal: |
Nat Genet |
Title: |
Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. |
Volume: |
41 |
Issue: |
9 |
Pages: |
977-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dudok JJ |
Year: |
2016 |
Journal: |
Neurosci Res |
Title: |
Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon. |
Volume: |
108 |
|
Pages: |
12-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li CY |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
αE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. |
Volume: |
7 |
|
Pages: |
12133 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tinkle CL |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. |
Volume: |
105 |
Issue: |
40 |
Pages: |
15405-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dudok JJ |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. |
Volume: |
33 |
Issue: |
19 |
Pages: |
8518-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carpinelli MR |
Year: |
2020 |
Journal: |
Dis Model Mech |
Title: |
Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure. |
Volume: |
13 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Krawchuk D |
Year: |
2015 |
Journal: |
J Cell Sci |
Title: |
Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo. |
Volume: |
128 |
Issue: |
5 |
Pages: |
1011-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hernández-MartÃnez R |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
p120-catenin regulates WNT signaling and EMT in the mouse embryo. |
Volume: |
116 |
Issue: |
34 |
Pages: |
16872-16881 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hendley AM |
Year: |
2015 |
Journal: |
Dev Biol |
Title: |
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. |
Volume: |
399 |
Issue: |
1 |
Pages: |
41-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sawallisch C |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. |
Volume: |
284 |
Issue: |
14 |
Pages: |
9225-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miao L |
Year: |
2024 |
Journal: |
Cardiovasc Res |
Title: |
β1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation. |
Volume: |
120 |
Issue: |
11 |
Pages: |
1279-1294 |
|
•
•
•
•
•
|
Publication |
First Author: |
Libusova L |
Year: |
2010 |
Journal: |
Development |
Title: |
N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. |
Volume: |
137 |
Issue: |
14 |
Pages: |
2297-305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu X |
Year: |
2006 |
Journal: |
Genes Dev |
Title: |
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. |
Volume: |
20 |
Issue: |
5 |
Pages: |
571-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirano M |
Year: |
2008 |
Journal: |
J Cell Biol |
Title: |
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition. |
Volume: |
182 |
Issue: |
6 |
Pages: |
1217-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ihermann-Hella A |
Year: |
2018 |
Journal: |
Stem Cell Reports |
Title: |
Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation. |
Volume: |
11 |
Issue: |
4 |
Pages: |
912-928 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rohacek AM |
Year: |
2017 |
Journal: |
Dev Cell |
Title: |
ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. |
Volume: |
43 |
Issue: |
3 |
Pages: |
318-331.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertol JW |
Year: |
2022 |
Journal: |
Development |
Title: |
TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells. |
Volume: |
149 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lee S |
Year: |
2020 |
Journal: |
Development |
Title: |
Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. |
Volume: |
147 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2002 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
9 |
Issue: |
5 |
Pages: |
179-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientfic Curators |
Year: |
2013 |
|
Title: |
Curated associations of genes in MGI and UniProt sequence records |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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|
|
•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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DO Term |
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•
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•
•
•
|
GXD Expression |
Probe: |
MGI:6113280 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7486722 |
Age: |
embryonic day 10.5 |
Image: |
S3E/F |
Note: |
Localized mostly to the zonula adherens and did not appear to strongly colocalize with Ctnnd1 in prominent actomyosin filaments that spanned the apical cortex. |
Specimen Label: |
S3E/F |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6113280 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1667217 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7486722 |
Age: |
embryonic day 10.5 |
Image: |
5G |
Note: |
Localized mostly to the zonula adherens and did not appear to strongly colocalize with Ctnnd1 in prominent actomyosin filaments that spanned the apical cortex. |
Specimen Label: |
5G |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
ESRP2 has been identified as an epithelial cell type-specific regulator of fibroblast growth factor receptor 2 (FGFR2) splicing []. It is required for expression of epithelial FGFR2-IIIb and the regulation of CD44, CTNND1 (also termed p120-Catenin) and ENAH (also termed hMena) splicing. It enhances epithelial-specific exons of CD44 and ENAH, silences mesenchymal exons of CTNND1, or both within FGFR2 []. ESRP2 contains three RNA recognition motifs (RRMs). |
|
•
•
•
•
•
|
Publication |
First Author: |
Warzecha CC |
Year: |
2009 |
Journal: |
Mol Cell |
Title: |
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. |
Volume: |
33 |
Issue: |
5 |
Pages: |
591-601 |
|
•
•
•
•
•
|
Publication |
First Author: |
Warzecha CC |
Year: |
2009 |
Journal: |
RNA Biol |
Title: |
The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. |
Volume: |
6 |
Issue: |
5 |
Pages: |
546-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leontieva OV |
Year: |
2009 |
Journal: |
Cell Cycle |
Title: |
RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer. |
Volume: |
8 |
Issue: |
3 |
Pages: |
490-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fagoonee S |
Year: |
2017 |
Journal: |
Oncotarget |
Title: |
The RNA-binding protein ESRP1 promotes human colorectal cancer progression. |
Volume: |
8 |
Issue: |
6 |
Pages: |
10007-10024 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RNA recognition motif 1 (RRM1) of epithelial splicing regulatory protein 1 (ESRP1). ESRP1 has been identified as an epithelial cell type-specific regulator of fibroblast growth factor receptor 2 (FGFR2) splicing []. It is required for expression of epithelial FGFR2-IIIb and the regulation of CD44, CTNND1 (p120-Catenin) and ENAH (hMena) splicing. It enhances epithelial-specific exons of CD44 and ENAH, silences mesenchymal exons of CTNND1, or both within FGFR2 []. ESRP1 has been shown to function as a tumour suppressor in colon cancer cells, due to its ability to bind to the 5' UTR of several cancer-related genes and regulate their translation []. However, high ESRP1 expression has been linked to colorectal cancer progression []. ESRP1 contains three RNA recognition motifs (RRMs). |
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•
•
•
•
•
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Publication |
First Author: |
Shen LF |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver. |
Volume: |
7 |
Issue: |
1 |
Pages: |
2182 |
|
•
•
•
•
•
|
Publication |
First Author: |
Witkowski MT |
Year: |
2017 |
Journal: |
J Exp Med |
Title: |
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome. |
Volume: |
214 |
Issue: |
3 |
Pages: |
773-791 |
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•
•
•
•
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Publication |
First Author: |
Gong R |
Year: |
2021 |
Journal: |
Pharmacol Res |
Title: |
Loss of m(6)A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury. |
Volume: |
174 |
|
Pages: |
105845 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
512
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
680
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
717
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
592
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
659
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
681
 |
Fragment?: |
false |
|
•
•
•
•
•
|