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Search results 301 to 379 out of 379 for Ctsd

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Type Details Score
Publication
30985297 | J:296116
First Author: Hirose T
Year: 2019
Journal: J Clin Invest
Title: ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.
Volume: 129
Issue: 5
Pages: 2145-2162
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Publication
22854957 | J:186307
First Author: Peng C
Year: 2012
Journal: J Biol Chem
Title: Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.
Volume: 287
Issue: 39
Pages: 32861-73
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Publication
20551175 | J:161201
First Author: Gao N
Year: 2010
Journal: Genes Dev
Title: Cdx2 regulates endo-lysosomal function and epithelial cell polarity.
Volume: 24
Issue: 12
Pages: 1295-305
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Publication
37115925 | J:335426
First Author: Butera A
Year: 2023
Journal: Sci Adv
Title: ZFP750 affects the cutaneous barrier through regulating lipid metabolism.
Volume: 9
Issue: 17
Pages: eadg5423
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22904094 | J:212629
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26
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Publication
25915474 | J:222854
First Author: Laguna A
Year: 2015
Journal: Nat Neurosci
Title: Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Volume: 18
Issue: 6
Pages: 826-35
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Publication
19799774 | J:157314
First Author: Ling KH
Year: 2009
Journal: Genome Biol
Title: Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.
Volume: 10
Issue: 10
Pages: R104
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Publication
21862448 | J:198109
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
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Publication
28071719 | J:265607
 
First Author: Naba A
Year: 2017
Journal: Sci Rep
Title: Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Volume: 7
Pages: 40495
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Publication
15582152 | J:102103
First Author: Jensen P
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A neurogenomics approach to gene expression analysis in the developing brain.
Volume: 132
Issue: 2
Pages: 116-27
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Publication
24154525 | J:205051
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Ctsd<tm1Cptr> | MGI:2182078
Name: cathepsin D; targeted mutation 1, Cristoph Peters
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ctsd<tm1.1Thre> | MGI:5702318
Name: cathepsin D; targeted mutation 1.1, Thomas Reinheckel
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Ctsd<m1J> | MGI:5752221
Name: cathepsin D; mutation 1, Jackson
Allele Type: Spontaneous
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Ctsd/Ctsd
Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctsd/Ctsd Edil3/Edil3<+>
Background: involves: C57BL/6 * C57BL/6N * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctsd/Ctsd Tg(Nes-cre)1Kln/?
Background: involves: C57BL/6 * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctsd/Ctsd
Background: C3HeB/FeJ-Ctsd/GrsrJ
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110725 | neuronal ceroid lipofuscinosis 10
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Publication
15321718 | -
First Author: Fujimoto Z
Year: 2004
Journal: J Mol Biol
Title: Crystal structure of aspartic proteinase from Irpex lacteus in complex with inhibitor pepstatin.
Volume: 341
Issue: 5
Pages: 1227-35
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Publication
17651737 | -
First Author: Pinti M
Year: 2007
Journal: FEBS Lett
Title: Identification and characterization of an aspartyl protease from Cryptococcus neoformans.
Volume: 581
Issue: 20
Pages: 3882-6
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Publication
17275325 | -
First Author: Vickers I
Year: 2007
Journal: Protein Expr Purif
Title: Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus.
Volume: 53
Issue: 1
Pages: 216-24
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Publication
21540129 | -
First Author: Bhaumik P
Year: 2012
Journal: Biochim Biophys Acta
Title: Structural studies of vacuolar plasmepsins.
Volume: 1824
Issue: 1
Pages: 207-23
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Publication
26008185 | -
First Author: Zhang J
Year: 2015
Journal: Protein Pept Lett
Title: Structure-Based Design of Mucor pusillus Pepsin for the Improved Ratio of Clotting Activity/Proteolytic Activity in Cheese Manufacture.
Volume: 22
Issue: 7
Pages: 660-7
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Protein Domain
IPR034164 | Pepsin-like_dom
Type: Domain
Description: This entry represents a domain found in a group of pepsin-like aspartic proteases. They are found in mammals, plants, fungi and bacteria and are classified by MEROPS as members of the peptidase family A1 (pepsin A, clan AA) []. Proteins containing this domain also include the fungal enzymes mucorpepsin (A01.013) [], polyporopepsin (A01.019) [], CtsD peptidase from Aspergillus (A01.077) []and CnAP1 peptidase from Cryptococcus neoformans (A01.078) []; plasmepsins from the malaria parasite Plasmodium (A01.021, A01.022, A01.023, A01.043, A01.059) []and shewasin A from the bacterium Shewanella (A01.095) [].
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Publication
35649359 | J:326469
First Author: Ding P
Year: 2022
Journal: Cell Rep
Title: Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.
Volume: 39
Issue: 9
Pages: 110851
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Publication
39744681 | J:361237
First Author: Park M
Year: 2025
Journal: Theranostics
Title: Targeted demethylation of cathepsin D via epigenome editing rescues pathology in Alzheimer's disease mouse model.
Volume: 15
Issue: 2
Pages: 428-438
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Publication
33910020 | J:311268
First Author: Lie PPY
Year: 2021
Journal: Cell Rep
Title: Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons.
Volume: 35
Issue: 4
Pages: 109034
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Publication
28073925 | J:242512
First Author: Tanaka Y
Year: 2017
Journal: Hum Mol Genet
Title: Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Volume: 26
Issue: 5
Pages: 969-988
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Publication
26042865 | J:258701
First Author: Kanamori H
Year: 2015
Journal: Autophagy
Title: Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes.
Volume: 11
Issue: 7
Pages: 1146-60
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Publication
22619379 | J:356441
First Author: Cluzeau CV
Year: 2012
Journal: Hum Mol Genet
Title: Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1.
Volume: 21
Issue: 16
Pages: 3632-46
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Publication
25484084 | J:319074
First Author: Sarkar C
Year: 2014
Journal: Autophagy
Title: Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.
Volume: 10
Issue: 12
Pages: 2208-22
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Publication
37144628 | J:335763
First Author: Ouyang X
Year: 2023
Journal: Physiol Rep
Title: Cardiomyocyte ZKSCAN3 regulates remodeling following pressure-overload.
Volume: 11
Issue: 9
Pages: e15686
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Publication
26727396 | J:303055
First Author: Xie C
Year: 2016
Journal: Autophagy
Title: Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury.
Volume: 12
Issue: 2
Pages: 410-23
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Publication
23242143 | J:303226
First Author: Martinet W
Year: 2013
Journal: Autophagy
Title: Immunohistochemical analysis of macroautophagy: recommendations and limitations.
Volume: 9
Issue: 3
Pages: 386-402
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Publication
31856641 | J:337420
First Author: Nakashima A
Year: 2020
Journal: Autophagy
Title: Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia.
Volume: 16
Issue: 10
Pages: 1771-1785
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Publication
35645744 | J:325703
 
First Author: Tucker AE
Year: 2022
Journal: Front Behav Neurosci
Title: Chronic Ethanol Causes Persistent Increases in Alzheimer's Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment.
Volume: 16
Pages: 886634
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Publication
31441382 | J:303310
First Author: Salazar G
Year: 2020
Journal: Autophagy
Title: SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
Volume: 16
Issue: 6
Pages: 1092-1110
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Publication
34403298 | J:325611
First Author: Wang L
Year: 2022
Journal: Autophagy
Title: Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy.
Volume: 18
Issue: 4
Pages: 765-782
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Publication
21749650 | -
First Author: Simões I
Year: 2011
Journal: FEBS J
Title: Shewasin A, an active pepsin homolog from the bacterium Shewanella amazonensis.
Volume: 278
Issue: 17
Pages: 3177-86
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Publication
7674916 | -
 
First Author: Rawlings ND
Year: 1995
Journal: Methods Enzymol
Title: Families of aspartic peptidases, and those of unknown catalytic mechanism.
Volume: 248
Pages: 105-20
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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