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Search results 301 to 396 out of 396 for Dctn2

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Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065913
Specimen Label: RBRC_1065913
Detected: true
Specimen Num: 207
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065915
Specimen Label: RBRC_1065915
Detected: true
Specimen Num: 208
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065845
Specimen Label: RBRC_1065845
Detected: true
Specimen Num: 173
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065665
Specimen Label: RBRC_1065665
Detected: true
Specimen Num: 83
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065667
Specimen Label: RBRC_1065667
Detected: true
Specimen Num: 84
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065669
Specimen Label: RBRC_1065669
Detected: true
Specimen Num: 85
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065671
Specimen Label: RBRC_1065671
Detected: true
Specimen Num: 86
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065673
Specimen Label: RBRC_1065673
Detected: true
Specimen Num: 87
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065675
Specimen Label: RBRC_1065675
Detected: true
Specimen Num: 88
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065677
Specimen Label: RBRC_1065677
Detected: true
Specimen Num: 89
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065679
Specimen Label: RBRC_1065679
Detected: true
Specimen Num: 90
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065681
Specimen Label: RBRC_1065681
Detected: true
Specimen Num: 91
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065683
Specimen Label: RBRC_1065683
Detected: true
Specimen Num: 92
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065685
Specimen Label: RBRC_1065685
Detected: true
Specimen Num: 93
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065687
Specimen Label: RBRC_1065687
Detected: true
Specimen Num: 94
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065689
Specimen Label: RBRC_1065689
Detected: true
Specimen Num: 95
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065691
Specimen Label: RBRC_1065691
Detected: true
Specimen Num: 96
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065865
Specimen Label: RBRC_1065865
Detected: true
Specimen Num: 183
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065867
Specimen Label: RBRC_1065867
Detected: true
Specimen Num: 184
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065869
Specimen Label: RBRC_1065869
Detected: true
Specimen Num: 185
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065871
Specimen Label: RBRC_1065871
Detected: true
Specimen Num: 186
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065873
Specimen Label: RBRC_1065873
Detected: true
Specimen Num: 187
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065875
Specimen Label: RBRC_1065875
Detected: true
Specimen Num: 188
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065877
Specimen Label: RBRC_1065877
Detected: true
Specimen Num: 189
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065879
Specimen Label: RBRC_1065879
Detected: true
Specimen Num: 190
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065881
Specimen Label: RBRC_1065881
Detected: true
Specimen Num: 191
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065883
Specimen Label: RBRC_1065883
Detected: true
Specimen Num: 192
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065885
Specimen Label: RBRC_1065885
Detected: true
Specimen Num: 193
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065887
Specimen Label: RBRC_1065887
Detected: true
Specimen Num: 194
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065889
Specimen Label: RBRC_1065889
Detected: true
Specimen Num: 195
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065891
Specimen Label: RBRC_1065891
Detected: true
Specimen Num: 196
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065893
Specimen Label: RBRC_1065893
Detected: true
Specimen Num: 197
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065839
Specimen Label: RBRC_1065839
Detected: true
Specimen Num: 170
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065841
Specimen Label: RBRC_1065841
Detected: true
Specimen Num: 171
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1066041
Specimen Label: RBRC_1066041
Detected: true
Specimen Num: 271
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065707
Specimen Label: RBRC_1065707
Detected: true
Specimen Num: 104
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691103
Age: postnatal adult
Image: RBRC_1065907
Specimen Label: RBRC_1065907
Detected: true
Specimen Num: 204
Publication
First Author: Abe TK
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Dynactin is essential for growth cone advance.
Volume: 372
Issue: 3
Pages: 418-22
Publication
First Author: Hoogenraad CC
Year: 2001
Journal: EMBO J
Title: Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes.
Volume: 20
Issue: 15
Pages: 4041-54
Publication
First Author: Xu M
Year: 2013
Journal: Biochim Biophys Acta
Title: Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes.
Volume: 1833
Issue: 12
Pages: 3228-3236
Publication
First Author: Moore CA
Year: 2005
Journal: Reproduction
Title: PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles.
Volume: 130
Issue: 3
Pages: 311-20
Publication
First Author: Dixit R
Year: 2008
Journal: Science
Title: Differential regulation of dynein and kinesin motor proteins by tau.
Volume: 319
Issue: 5866
Pages: 1086-9
Publication
First Author: Splinter D
Year: 2012
Journal: Mol Biol Cell
Title: BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures.
Volume: 23
Issue: 21
Pages: 4226-41
Publication
First Author: Ohbayashi N
Year: 2012
Journal: J Cell Sci
Title: Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Volume: 125
Issue: Pt 6
Pages: 1508-18
Publication
First Author: Lien WH
Year: 2008
Journal: J Cell Biol
Title: Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic.
Volume: 183
Issue: 6
Pages: 989-97
Publication
First Author: Papal S
Year: 2013
Journal: Hum Mol Genet
Title: The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.
Volume: 22
Issue: 18
Pages: 3773-88
Publication
First Author: Quesnel-Vallières M
Year: 2015
Journal: Genes Dev
Title: Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.
Volume: 29
Issue: 7
Pages: 746-59
Publication
First Author: Choo HJ
Year: 2016
Journal: Stem Cells
Title: Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.
Volume: 34
Issue: 11
Pages: 2784-2797
Publication
First Author: Vaughan KT
Year: 1996
Journal: Genomics
Title: Multiple mouse chromosomal loci for dynein-based motility.
Volume: 36
Issue: 1
Pages: 29-38
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Eckley DM
Year: 1999
Journal: J Cell Biol
Title: Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end.
Volume: 147
Issue: 2
Pages: 307-20
Protein
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: false
Publication
First Author: Jin T
Year: 2002
Journal: J Biol Chem
Title: Dynamitin controls Beta 2 integrin avidity by modulating cytoskeletal constraint on integrin molecules.
Volume: 277
Issue: 36
Pages: 32963-9
Publication
First Author: Kardon JR
Year: 2009
Journal: Nat Rev Mol Cell Biol
Title: Regulators of the cytoplasmic dynein motor.
Volume: 10
Issue: 12
Pages: 854-65
Publication  
First Author: Holleran EA
Year: 1998
Journal: Int Rev Cytol
Title: The role of the dynactin complex in intracellular motility.
Volume: 182
Pages: 69-109
Publication
First Author: Karki S
Year: 1999
Journal: Curr Opin Cell Biol
Title: Cytoplasmic dynein and dynactin in cell division and intracellular transport.
Volume: 11
Issue: 1
Pages: 45-53
Protein Domain
Type: Family
Description: Dynactin is a multiprotein complex necessary for the function of microtubule motor protein dynein. The dynein-dynactin complex is involved in a variety of cellular events, includingmembrane vesicle transport, mitotic spindle assembly and centrosome separation [, , ].Dynamitin (dynactin subunit 2, DCTN2) is a subunit of the dynactin complex. In Saccharomyces cerevisiae it is also known as Jnm1. Dynactin contains two distinct structural domains: a projecting sidearm that interacts with dynein and an actin-like minifilament backbone that is thought to bind cargo. Dynamitin holds together both structural domains []. Dynamitin is implicated in cell adhesion by binding to macrophage-enriched myristoylated alanine-rice C kinase substrate (MacMARCKS) []. In mice, DCTN2 is involved in anchoring microtubules to centrosomes and may play a role in synapse formation during brain development [].