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Search results 301 to 377 out of 377 for Dgcr2

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Type Details Score
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30901624 | -
 
First Author: Belangero SI
Year: 2019
Journal: Psychiatry Res
Title: DGCR2 influences cortical thickness through a mechanism independent of schizophrenia pathogenesis.
Volume: 274
Pages: 391-394
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Allele
Dgcr2<em1Smoc> | MGI:7289322
Name: DiGeorge syndrome critical region gene 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hira<em1Smoc> | MGI:7290221
Name: histone cell cycle regulator; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
Q3TPM7
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: true
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Protein Domain
IPR042378 | IDD
Type: Family
Description: DGCR2 is an activity-dependent adhesion protein that has been associated with schizophrenia []. It has been shown to regulate critical steps of early corticogenesis possibly through a Reelin-dependent mechanism [].
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Allele
Del(16Dgcr2-Hira)3Aam | MGI:3798964
Name: deletion, Chr 16, Alea A Mills 3
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
8776594 | -
First Author: Gong W
Year: 1996
Journal: Hum Mol Genet
Title: A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11.
Volume: 5
Issue: 6
Pages: 789-800
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Publication
7655455 | -
First Author: Wadey R
Year: 1995
Journal: Hum Mol Genet
Title: Isolation of a gene encoding an integral membrane protein from the vicinity of a balanced translocation breakpoint associated with DiGeorge syndrome.
Volume: 4
Issue: 6
Pages: 1027-33
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Publication
12175881 | -
First Author: Maynard TM
Year: 2002
Journal: Int J Dev Neurosci
Title: 22q11 DS: genomic mechanisms and gene function in DiGeorge/velocardiofacial syndrome.
Volume: 20
Issue: 3-5
Pages: 407-19
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Protein Domain
IPR034010 | DGCR2-like_CTLD
Type: Domain
Description: This C-type lectin-like domain (CTLD) is found in DGCR2, an integral membrane protein deleted in DiGeorge Syndrome (DGS). CTLD refers to a domain homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins. DGS is also known velo-cardio-facial syndrome (VCFS). DGS is a genetic abnormality that results in malformations of the heart, face, and limbs and is associated with schizophrenia and depressive disorders. DGCR2 is a candidate for involvement in the pathogenesis of DGS since the DGCR2 gene lies within the minimal DGS critical region (MDGRC) of 22q11, which when deleted gives rise to DGS, and the DGCR2 gene is in close proximity to the balanced translocation breakpoint in a DGS patient having a balanced translocation [, , ].
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Strain
MGI:5910627 | B6.129S7-Del(16Dgcr2-Hira)3Aam
Attribute String: congenic, deletion, mutant strain, targeted mutation, chromosome aberration
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Publication
21635953 | J:178046
First Author: Drew LJ
Year: 2011
Journal: Mol Cell Neurosci
Title: Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion.
Volume: 47
Issue: 4
Pages: 293-305
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Publication
26748091 | J:230876
First Author: Piskorowski RA
Year: 2016
Journal: Neuron
Title: Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome.
Volume: 89
Issue: 1
Pages: 163-76
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Publication
24027283 | J:202335
First Author: Fénelon K
Year: 2013
Journal: J Neurosci
Title: The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion.
Volume: 33
Issue: 37
Pages: 14825-39
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Publication
26898776 | J:230859
First Author: Tamura M
Year: 2016
Journal: Neuron
Title: Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition.
Volume: 89
Issue: 5
Pages: 1100-9
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Publication
33077947 | J:299952
First Author: Donegan ML
Year: 2020
Journal: Nat Neurosci
Title: Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model.
Volume: 23
Issue: 11
Pages: 1365-1375
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Publication
20360742 | J:158957
First Author: Sigurdsson T
Year: 2010
Journal: Nature
Title: Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia.
Volume: 464
Issue: 7289
Pages: 763-7
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Publication
37968289 | J:342597
First Author: Rummell BP
Year: 2023
Journal: Nat Commun
Title: Altered corollary discharge signaling in the auditory cortex of a mouse model of schizophrenia predisposition.
Volume: 14
Issue: 1
Pages: 7388
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Strain
MGI:6354736 | C57BL/6JSmoc-Dgcr2<em1Smoc> Hira<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Del(16Dgcr2-Hira)3Aam/+
Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(16Dgcr2-Hira)3Aam/+
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(16Dgcr2-Hira)3Aam/+
Background: involves: 129S7/SvEvBrd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(16Dgcr2-Hira)3Aam/+
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(16Dgcr2-Hira)3Aam/+
Background: B6.129S7-Del(16Dgcr2-Hira)3Aam
Zygosity: ht
Has Mutant Allele: true
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Publication
25913858 | J:221568
First Author: Mukai J
Year: 2015
Journal: Neuron
Title: Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia.
Volume: 86
Issue: 3
Pages: 680-95
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Publication
18836441 | J:141432
First Author: Mukai J
Year: 2008
Journal: Nat Neurosci
Title: Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion.
Volume: 11
Issue: 11
Pages: 1302-10
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Publication
28696314 | J:243862
First Author: Diamantopoulou A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Loss-of-function mutation in Mirta22/Emc10 rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion.
Volume: 114
Issue: 30
Pages: E6127-E6136
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Publication
23332760 | J:193500
First Author: Xu B
Year: 2013
Journal: Cell
Title: Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion.
Volume: 152
Issue: 1-2
Pages: 262-75
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Protein
A0A338P7A8
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Publication
35680927 | J:328657
First Author: Rabadan MA
Year: 2022
Journal: Nat Commun
Title: An in vitro model of neuronal ensembles.
Volume: 13
Issue: 1
Pages: 3340
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Publication
28384469 | J:253243
First Author: Hamm JP
Year: 2017
Journal: Neuron
Title: Altered Cortical Ensembles in Mouse Models of Schizophrenia.
Volume: 94
Issue: 1
Pages: 153-167.e8
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Publication
27507786 | J:235604
First Author: Nilsson SR
Year: 2016
Journal: Cereb Cortex
Title: Assessing the Cognitive Translational Potential of a Mouse Model of the 22q11.2 Microdeletion Syndrome.
Volume: 26
Issue: 10
Pages: 3991-4003
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Publication
30675529 | J:278079
 
First Author: Murano T
Year: 2019
Journal: Commun Biol
Title: Transcriptomic immaturity inducible by neural hyperexcitation is shared by multiple neuropsychiatric disorders.
Volume: 2
Pages: 32
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Publication
28869582 | J:258045
First Author: Zaremba JD
Year: 2017
Journal: Nat Neurosci
Title: Impaired hippocampal place cell dynamics in a mouse model of the 22q11.2 deletion.
Volume: 20
Issue: 11
Pages: 1612-1623
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Publication
37590138 | J:340024
First Author: Brockway DF
Year: 2023
Journal: Cell Rep
Title: Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior.
Volume: 42
Issue: 8
Pages: 112976
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Publication
22900207 | J:196805
 
First Author: Nomura J
Year: 2012
Journal: Neural Plast
Title: Animal models of psychiatric disorders that reflect human copy number variation.
Volume: 2012
Pages: 589524
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Protein
P98154
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
Q6P5A9
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
Q8C2R4
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
A0A0R4J1M6
Organism: Mus musculus/domesticus
Length: 546  
Fragment?: false
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Protein
Q3TQ62
Organism: Mus musculus/domesticus
Length: 546  
Fragment?: false
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Protein
E9QNU3
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
Q8CB23
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
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Protein
Q3UZE8
Organism: Mus musculus/domesticus
Length: 400  
Fragment?: true
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Protein
Q6ZQH9
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: true
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Publication
21821099 | J:184660
 
First Author: Kvajo M
Year: 2012
Journal: Neuroscience
Title: Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.
Volume: 211
Pages: 136-64
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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