Type |
Details |
Score |
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap OST37839, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap OST53647, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like exosome 3'-5' exoribonuclease; gene trap OST253764, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like exosome 3'-5' exoribonuclease; gene trap OST448046, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 1, Jurien Dean |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like exosome 3'-5' exoribonuclease; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 1, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
958
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hunter RW |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
Loss of Dis3l2 partially phenocopies Perlman syndrome in mice and results in up-regulation of Igf2 in nephron progenitor cells. |
Volume: |
32 |
Issue: |
13-14 |
Pages: |
903-908 |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; gene trap AY0051, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; gene trap AA0173, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; gene trap E284A06, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; gene trap OST30317, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, gene trap |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap AN0948, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; gene trap EUCE313a02, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; gene trap EUCE0253b08, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap EUCJ00134a11, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST11687F2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST13223C11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST13725F7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST14096G4, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST14474E5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST14668C6, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; gene trap IST15087A5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; targeted mutation 1e.1, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 4, Joshua T Mendell |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 1, Joshua T Mendell |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 2, Joshua T Mendell |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 3, Joshua T Mendell |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 1, Baylor College of Medicine |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; targeted mutation 1.1, Uttiya Basu |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 10, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like 3'-5' exoribonuclease 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 like exosome 3'-5' exoribonuclease; endonuclease-mediated mutation 1, Institute of Molecular Genetics |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; endonuclease-mediated mutation 1, Jurien Dean |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; endonuclease-mediated mutation 2, Jurien Dean |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang HM |
Year: |
2013 |
Journal: |
Nature |
Title: |
A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. |
Volume: |
497 |
Issue: |
7448 |
Pages: |
244-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Faehnle CR |
Year: |
2014 |
Journal: |
Nature |
Title: |
Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. |
Volume: |
514 |
Issue: |
7521 |
Pages: |
252-256 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation, coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, endonuclease-mediated mutation, coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
endonuclease-mediated mutation, coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, endonuclease-mediated mutation, coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
endonuclease-mediated mutation, mutant stock |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 |
Background: |
C57BL/6J-Dis3l2 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 |
Background: |
C57BL/6J-Dis3l2 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 Tg(Zp3-cre)93Knw/? |
Background: |
involves: C57BL/6 * C57BL/6J * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 |
Background: |
C57BL/6N-Dis3l2/BayMmucd |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3 |
Background: |
C57BL/6N-Dis3/Ieg |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 |
Background: |
involves: C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3 |
Background: |
involves: C57BL/6 * DBA/2 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 Tg(Zp3-cre)93Knw/? |
Background: |
involves: C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 Tg(Stra8-icre)1Reb/? |
Background: |
involves: C57BL/6 * DBA/2 * FVB/NJ |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2<+> |
Background: |
C57BL/6N-Dis3l2/BayMmucd |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l/Dis3l<+> |
Background: |
C57BL/6NCrl-Dis3l/Ccpcz |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2<+> |
Background: |
involves: C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2<+> |
Background: |
involves: C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3 Tg(Stra8-icre)1Reb/? |
Background: |
involves: C57BL/6 * DBA/2 * FVB/NJ |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3 Tg(Zp3-cre)93Knw/? |
Background: |
involves: C57BL/6J * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3l2/Dis3l2 Wt1/Wt1<+> |
Background: |
involves: 129S4/SvJae * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3<+> |
Background: |
C57BL/6N-Dis3/Ieg |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3<+> |
Background: |
involves: C57BL/6 * DBA/2 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3 Exosc10/Exosc10 Tg(Zp3-cre)93Knw/? |
Background: |
involves: C57BL/6J * DBA/2J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dis3/Dis3 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Igh/Igh Dis3/Dis3 Aicda/Aicda<+> |
Background: |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Chesi M |
Year: |
2020 |
Journal: |
Blood Cancer Discov |
Title: |
Monosomic loss of MIR15A/MIR16-1 is a driver of multiple myeloma proliferation and disease progression. |
Volume: |
1 |
Issue: |
1 |
Pages: |
68-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|