| Type |
Details |
Score |
| Publication |
| First Author: |
Sekiyama N |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1. |
| Volume: |
112 |
| Issue: |
30 |
| Pages: |
E4036-45 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-A1-1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-A1-2 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-A2-1 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-A2-2 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-B1-1 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-B1-2 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-B2-1 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-B2-2 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-C1-1 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-C1-2 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-C2-1 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 1.5 |
|
|
| Specimen Label: |
2-cell-C2-2 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A1-1 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A1-2 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A2-1 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A2-2 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A3-1 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A3-2 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A4-1 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-A4-2 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B1-1 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B1-2 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B2-1 |
| Detected: |
true |
| Specimen Num: |
23 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B2-2 |
| Detected: |
true |
| Specimen Num: |
24 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B3-1 |
| Detected: |
true |
| Specimen Num: |
25 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B3-2 |
| Detected: |
true |
| Specimen Num: |
26 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B4-1 |
| Detected: |
true |
| Specimen Num: |
27 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-B4-2 |
| Detected: |
true |
| Specimen Num: |
28 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C1-1 |
| Detected: |
true |
| Specimen Num: |
29 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C1-2 |
| Detected: |
true |
| Specimen Num: |
30 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C2-1 |
| Detected: |
true |
| Specimen Num: |
31 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C2-2 |
| Detected: |
true |
| Specimen Num: |
32 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C3-1 |
| Detected: |
true |
| Specimen Num: |
33 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C3-2 |
| Detected: |
true |
| Specimen Num: |
34 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C4-1 |
| Detected: |
true |
| Specimen Num: |
35 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289018 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2011-10-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318643 |
|
| Stage: |
TS03 |
| Assay Id: |
MGI:5289609 |
| Age: |
embryonic day 2.0 |
|
|
| Specimen Label: |
4-cell-C4-2 |
| Detected: |
true |
| Specimen Num: |
36 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:942144 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-08-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7516917 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Supplementary table 2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
other, transgenic, mutant strain, coisogenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Steiner JL |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
e99582 |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap OST9003, Lexicon Genetics |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
207
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
217
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aguilar-Valles A |
| Year: |
2015 |
| Journal: |
J Neurosci |
| Title: |
Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2. |
| Volume: |
35 |
| Issue: |
31 |
| Pages: |
11125-32 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
983
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564033 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564070 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression colocalized with Eif4e in subpopulation of punctate cytoplasmic foci in radial precursor cell bodies. |
| Specimen Label: |
4B 4E-T (left) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Allele |
| Name: |
eukaryotic translation initiation factor 4E; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap AL0781, Wellcome Trust Sanger Institute |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap EUCE00126g01, Helmholtz Zentrum Muenchen GmbH |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap EUCE0238h03, Helmholtz Zentrum Muenchen GmbH |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; targeted mutation 1, Mammalian Functional Genomics Centre |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap 538A3, Centre for Modeling Human Disease |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap 147F6, Centre for Modeling Human Disease |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap 147.1G6, Centre for Modeling Human Disease |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; targeted mutation 1e, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; gene trap IST14077A4, Texas A&M Institute for Genomic Medicine |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; targeted mutation 1b, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Pier P Pandolfi |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ngdn/Ngdn |
| Background: |
C57BL/6N-Ngdn/Ieg |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shenberger JS |
| Year: |
2007 |
| Journal: |
Int J Biochem Cell Biol |
| Title: |
Roles of mitogen-activated protein kinase signal-integrating kinases 1 and 2 in oxidant-mediated eIF4E phosphorylation. |
| Volume: |
39 |
| Issue: |
10 |
| Pages: |
1828-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okumura F |
| Year: |
2007 |
| Journal: |
Genes Dev |
| Title: |
ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP. |
| Volume: |
21 |
| Issue: |
3 |
| Pages: |
255-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuo H |
| Year: |
1997 |
| Journal: |
Nat Struct Biol |
| Title: |
Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein. |
| Volume: |
4 |
| Issue: |
9 |
| Pages: |
717-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ibrahimo S |
| Year: |
2006 |
| Journal: |
Yeast |
| Title: |
Regulation of translation initiation by the yeast eIF4E binding proteins is required for the pseudohyphal response. |
| Volume: |
23 |
| Issue: |
14-15 |
| Pages: |
1075-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Andrei MA |
| Year: |
2005 |
| Journal: |
RNA |
| Title: |
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies. |
| Volume: |
11 |
| Issue: |
5 |
| Pages: |
717-27 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, congenic, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion #, Pier P Pandolfi |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(ACTB-Eif4e)#Ppp/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(ACTB-Eif4e)#Ppp/? |
| Background: |
B6.Cg-Tg(ACTB-Eif4e)#Ppp |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(ACTB-Eif4e)#Ppp/? |
| Background: |
involves: C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
959
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
245
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ngdn/Ngdn<+> |
| Background: |
C57BL/6N-Ngdn/Ieg |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peter D |
| Year: |
2015 |
| Journal: |
Genes Dev |
| Title: |
Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation. |
| Volume: |
29 |
| Issue: |
17 |
| Pages: |
1835-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MartÃnez A |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
e0123352 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Poulin F |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family. |
| Volume: |
273 |
| Issue: |
22 |
| Pages: |
14002-7 |
|
•
•
•
•
•
|