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Search results 301 to 400 out of 548 for Eif4e

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Type Details Score
Publication
First Author: Sekiyama N
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Volume: 112
Issue: 30
Pages: E4036-45
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-2
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-1
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-2
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-1
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289609
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-2
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-1
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-2
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-1
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-2
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-1
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-2
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-1
Detected: true
Specimen Num: 19
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-2
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-1
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-2
Detected: true
Specimen Num: 22
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-1
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-2
Detected: true
Specimen Num: 24
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-1
Detected: true
Specimen Num: 25
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-2
Detected: true
Specimen Num: 26
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-1
Detected: true
Specimen Num: 27
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-2
Detected: true
Specimen Num: 28
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-1
Detected: true
Specimen Num: 29
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-2
Detected: true
Specimen Num: 30
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C2-1
Detected: true
Specimen Num: 31
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C2-2
Detected: true
Specimen Num: 32
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C3-1
Detected: true
Specimen Num: 33
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C3-2
Detected: true
Specimen Num: 34
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C4-1
Detected: true
Specimen Num: 35
GXD Expression      
Probe: MGI:5289018
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289609
Age: embryonic day 2.0
Specimen Label: 4-cell-C4-2
Detected: true
Specimen Num: 36
GXD Expression    
Probe: MGI:942144
Assay Type: RNA in situ
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7516917
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Strain
Attribute String: other, transgenic, mutant strain, coisogenic
Publication
First Author: Steiner JL
Year: 2014
Journal: PLoS One
Title: Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice.
Volume: 9
Issue: 6
Pages: e99582
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap OST9003, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: neuroguidin, EIF4E binding protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
Publication
First Author: Aguilar-Valles A
Year: 2015
Journal: J Neurosci
Title: Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2.
Volume: 35
Issue: 31
Pages: 11125-32
Protein
Organism: Mus musculus/domesticus
Length: 983  
Fragment?: false
GXD Expression  
Probe: MGI:7564033
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7564070
Age: embryonic day 14.5
Note: Expression colocalized with Eif4e in subpopulation of punctate cytoplasmic foci in radial precursor cell bodies.
Specimen Label: 4B 4E-T (left)
Detected: true
Specimen Num: 2
Allele
Name: eukaryotic translation initiation factor 4E; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap AL0781, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap EUCE00126g01, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap EUCE0238h03, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele
Name: neuroguidin, EIF4E binding protein; targeted mutation 1, Mammalian Functional Genomics Centre
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap 538A3, Centre for Modeling Human Disease
Allele Type: Gene trapped
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap 147F6, Centre for Modeling Human Disease
Allele Type: Gene trapped
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap 147.1G6, Centre for Modeling Human Disease
Allele Type: Gene trapped
Allele
Name: neuroguidin, EIF4E binding protein; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: neuroguidin, EIF4E binding protein; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele  
Name: neuroguidin, EIF4E binding protein; gene trap IST14077A4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele
Name: neuroguidin, EIF4E binding protein; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Interaction Experiment
Description: Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.
Allele
Name: transgene insertion, Pier P Pandolfi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: Ngdn/Ngdn
Background: C57BL/6N-Ngdn/Ieg
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Shenberger JS
Year: 2007
Journal: Int J Biochem Cell Biol
Title: Roles of mitogen-activated protein kinase signal-integrating kinases 1 and 2 in oxidant-mediated eIF4E phosphorylation.
Volume: 39
Issue: 10
Pages: 1828-42
Publication
First Author: Okumura F
Year: 2007
Journal: Genes Dev
Title: ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP.
Volume: 21
Issue: 3
Pages: 255-60
Publication
First Author: Matsuo H
Year: 1997
Journal: Nat Struct Biol
Title: Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein.
Volume: 4
Issue: 9
Pages: 717-24
Publication
First Author: Ibrahimo S
Year: 2006
Journal: Yeast
Title: Regulation of translation initiation by the yeast eIF4E binding proteins is required for the pseudohyphal response.
Volume: 23
Issue: 14-15
Pages: 1075-88
Publication
First Author: Andrei MA
Year: 2005
Journal: RNA
Title: A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies.
Volume: 11
Issue: 5
Pages: 717-27
Strain
Attribute String: transgenic, congenic, mutant strain
Allele
Name: transgene insertion #, Pier P Pandolfi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Tg(ACTB-Eif4e)#Ppp/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(ACTB-Eif4e)#Ppp/?
Background: B6.Cg-Tg(ACTB-Eif4e)#Ppp
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(ACTB-Eif4e)#Ppp/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 959  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
Genotype
Symbol: Ngdn/Ngdn<+>
Background: C57BL/6N-Ngdn/Ieg
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Peter D
Year: 2015
Journal: Genes Dev
Title: Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation.
Volume: 29
Issue: 17
Pages: 1835-49
Publication
First Author: Martínez A
Year: 2015
Journal: PLoS One
Title: Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.
Volume: 10
Issue: 4
Pages: e0123352
Publication
First Author: Poulin F
Year: 1998
Journal: J Biol Chem
Title: 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family.
Volume: 273
Issue: 22
Pages: 14002-7