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Search results 301 to 400 out of 772 for Ep300

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Type Details Score
Publication  
First Author: Martins VF
Year: 2022
Journal: JCI Insight
Title: p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.
Volume: 7
Issue: 1
Publication
First Author: Boussouar F
Year: 2014
Journal: Andrology
Title: A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.
Volume: 2
Issue: 3
Pages: 351-9
Publication
First Author: Sandberg ML
Year: 2005
Journal: Dev Cell
Title: c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation.
Volume: 8
Issue: 2
Pages: 153-66
Publication
First Author: Bedford DC
Year: 2011
Journal: Cell Metab
Title: Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.
Volume: 14
Issue: 2
Pages: 219-30
Publication
First Author: Nakayama T
Year: 2024
Journal: Cell Rep
Title: Activator of KAT3 histone acetyltransferase family ameliorates a neurodevelopmental disorder phenotype in the syntaxin 1A ablated mouse model.
Volume: 43
Issue: 4
Pages: 114101
Publication
First Author: Syal C
Year: 2018
Journal: Sci Rep
Title: Ectopic expression of aPKC-mediated phosphorylation in p300 modulates hippocampal neurogenesis, CREB binding and fear memory differently with age.
Volume: 8
Issue: 1
Pages: 13489
Publication
First Author: He L
Year: 2014
Journal: J Endocrinol
Title: Potential biomarker of metformin action.
Volume: 221
Issue: 3
Pages: 363-9
Publication
First Author: Li Q
Year: 2002
Journal: J Gerontol A Biol Sci Med Sci
Title: Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.
Volume: 57
Issue: 3
Pages: B93-8
Publication
First Author: Warner DR
Year: 2002
Journal: In Vitro Cell Dev Biol Anim
Title: Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.
Volume: 38
Issue: 1
Pages: 48-53
Publication
First Author: Ferreon JC
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.
Volume: 106
Issue: 32
Pages: 13260-5
Publication
First Author: Partanen A
Year: 1999
Journal: Int J Dev Biol
Title: Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.
Volume: 43
Issue: 6
Pages: 487-94
Publication
First Author: Fu M
Year: 2005
Journal: J Biol Chem
Title: Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism.
Volume: 280
Issue: 33
Pages: 29728-42
Publication
First Author: Kwok RP
Year: 2006
Journal: Mol Reprod Dev
Title: Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.
Volume: 73
Issue: 7
Pages: 885-94
Publication
First Author: Bai Y
Year: 2005
Journal: J Immunol
Title: Protein acetylation regulates both PU.1 transactivation and Ig kappa 3' enhancer activity.
Volume: 175
Issue: 8
Pages: 5160-9
Publication
First Author: Hatta M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1.
Volume: 379
Issue: 4
Pages: 1005-8
Publication  
First Author: Chen G
Year: 2009
Journal: J Biomed Sci
Title: Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.
Volume: 16
Pages: 24
Publication
First Author: Zhong X
Year: 2009
Journal: J Biol Chem
Title: Critical roles of coactivator p300 in mouse embryonic stem cell differentiation and Nanog expression.
Volume: 284
Issue: 14
Pages: 9168-75
Publication
First Author: Ghisletti S
Year: 2010
Journal: Immunity
Title: Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.
Volume: 32
Issue: 3
Pages: 317-28
Publication
First Author: Liu Z
Year: 2010
Journal: J Immunol
Title: Lysine acetylation regulates Bruton's tyrosine kinase in B cell activation.
Volume: 184
Issue: 1
Pages: 244-54
Publication
First Author: Lee YH
Year: 2011
Journal: Genes Dev
Title: Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation.
Volume: 25
Issue: 2
Pages: 176-88
Publication
First Author: Nakagawa Y
Year: 2009
Journal: Circ Res
Title: p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.
Volume: 105
Issue: 8
Pages: 746-54
Publication
First Author: Dai YS
Year: 2001
Journal: J Biol Chem
Title: p300 Functions as a coactivator of transcription factor GATA-4.
Volume: 276
Issue: 40
Pages: 37178-85
Publication
First Author: Zheng S
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: 2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity.
Volume: 56
Issue: 1
Pages: 90-98
Publication
First Author: Dickerson KM
Year: 2022
Journal: Blood Cancer Discov
Title: ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia.
Volume: 3
Issue: 3
Pages: 240-263
Publication
First Author: Ceseña TI
Year: 2008
Journal: Mol Cell Endocrinol
Title: Acetylation and deacetylation regulate CCAAT/enhancer binding protein beta at K39 in mediating gene transcription.
Volume: 289
Issue: 1-2
Pages: 94-101
Publication
First Author: Thevenet L
Year: 2005
Journal: J Biol Chem
Title: NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY.
Volume: 280
Issue: 46
Pages: 38625-30
Publication
First Author: Xiao Y
Year: 2014
Journal: Cell Rep
Title: Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.
Volume: 7
Issue: 5
Pages: 1471-1480
Publication
First Author: Yao TP
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.
Volume: 93
Issue: 20
Pages: 10626-31
Publication
First Author: Yang D
Year: 1999
Journal: Circ Res
Title: Viral myocarditis: identification of five differentially expressed genes in coxsackievirus B3-infected mouse heart.
Volume: 84
Issue: 6
Pages: 704-12
Publication
First Author: Yao TP
Year: 1998
Journal: Cell
Title: Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.
Volume: 93
Issue: 3
Pages: 361-72
Publication
First Author: Kung AL
Year: 2000
Journal: Genes Dev
Title: Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.
Volume: 14
Issue: 3
Pages: 272-7
Publication
First Author: Forster N
Year: 2007
Journal: J Immunol
Title: p300 protein acetyltransferase activity suppresses systemic lupus erythematosus-like autoimmune disease in mice.
Volume: 178
Issue: 11
Pages: 6941-8
Publication
First Author: Xu W
Year: 2006
Journal: Blood
Title: Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells.
Volume: 107
Issue: 11
Pages: 4407-16
Publication  
First Author: Lee HH
Year: 2016
Journal: Sci Rep
Title: LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding.
Volume: 6
Pages: 24921
Publication
First Author: Kimura M
Year: 2022
Journal: Hepatol Commun
Title: Inhibition of CBP/β-catenin signaling ameliorated fibrosis in cholestatic liver disease.
Volume: 6
Issue: 10
Pages: 2732-2747
Publication
First Author: Kasper LH
Year: 2006
Journal: Mol Cell Biol
Title: Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development.
Volume: 26
Issue: 3
Pages: 789-809
Publication
First Author: Zhong J
Year: 2014
Journal: Cancer Res
Title: p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis.
Volume: 74
Issue: 6
Pages: 1870-1880
Publication
First Author: Azahri NS
Year: 2012
Journal: J Cell Biochem
Title: Sp1, acetylated histone-3 and p300 regulate TRAIL transcription: mechanisms of PDGF-BB-mediated VSMC proliferation and migration.
Volume: 113
Issue: 8
Pages: 2597-606
Publication
First Author: Kauppi M
Year: 2008
Journal: Blood
Title: Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice.
Volume: 112
Issue: 8
Pages: 3148-53
Publication
First Author: Kim JR
Year: 2009
Journal: J Biol Chem
Title: Enhancer of polycomb1 acts on serum response factor to regulate skeletal muscle differentiation.
Volume: 284
Issue: 24
Pages: 16308-16
Publication
First Author: de Graaf CA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Regulation of hematopoietic stem cells by their mature progeny.
Volume: 107
Issue: 50
Pages: 21689-94
Publication
First Author: Hilton DJ
Year: 2009
Journal: Blood
Title: Mutational inhibition of c-Myb or p300 ameliorates treatment-induced thrombocytopenia.
Volume: 113
Issue: 22
Pages: 5599-604
Publication
First Author: Lipinski M
Year: 2020
Journal: Nat Commun
Title: KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain.
Volume: 11
Issue: 1
Pages: 2588
Publication
First Author: Wilson MR
Year: 2020
Journal: Cell Rep
Title: ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation.
Volume: 33
Issue: 6
Pages: 108366
Publication
First Author: Wang SP
Year: 2017
Journal: Mol Cell
Title: A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.
Volume: 67
Issue: 2
Pages: 308-321.e6
Publication
First Author: Kimura T
Year: 2008
Journal: Biochem J
Title: Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex.
Volume: 415
Issue: 3
Pages: 477-82
Publication
First Author: Kim RH
Year: 2001
Journal: J Biol Chem
Title: SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators.
Volume: 276
Issue: 49
Pages: 46297-304
Publication
First Author: Bradney C
Year: 2003
Journal: J Biol Chem
Title: Regulation of E2A activities by histone acetyltransferases in B lymphocyte development.
Volume: 278
Issue: 4
Pages: 2370-6
Publication
First Author: Kang J
Year: 2005
Journal: Cell
Title: A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription.
Volume: 123
Issue: 5
Pages: 833-47
Publication
First Author: Takahashi N
Year: 2002
Journal: J Biol Chem
Title: Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma.
Volume: 277
Issue: 19
Pages: 16906-12
Publication
First Author: Toleman C
Year: 2004
Journal: J Biol Chem
Title: Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities.
Volume: 279
Issue: 51
Pages: 53665-73
Publication
First Author: Sen N
Year: 2008
Journal: Nat Cell Biol
Title: Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.
Volume: 10
Issue: 7
Pages: 866-73
Publication
First Author: Kimbrel EA
Year: 2009
Journal: Blood
Title: Systematic in vivo structure-function analysis of p300 in hematopoiesis.
Volume: 114
Issue: 23
Pages: 4804-12
Publication
First Author: Zhao W
Year: 2011
Journal: J Immunol
Title: NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages.
Volume: 186
Issue: 5
Pages: 3173-9
Publication
First Author: Wondisford AR
Year: 2014
Journal: J Biol Chem
Title: Control of Foxo1 gene expression by co-activator P300.
Volume: 289
Issue: 7
Pages: 4326-33
Publication
First Author: Lin G
Year: 2014
Journal: Mol Cell Endocrinol
Title: Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3.
Volume: 395
Issue: 1-2
Pages: 19-31
Publication
First Author: Magenta A
Year: 2003
Journal: Mol Cell Biol
Title: MyoD stimulates RB promoter activity via the CREB/p300 nuclear transduction pathway.
Volume: 23
Issue: 8
Pages: 2893-906
Publication
First Author: Sharma S
Year: 2016
Journal: Mol Cell
Title: Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2.
Volume: 63
Issue: 6
Pages: 927-38
Publication
First Author: Kasper LH
Year: 2010
Journal: EMBO J
Title: CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.
Volume: 29
Issue: 21
Pages: 3660-72
Publication
First Author: Wang FM
Year: 2011
Journal: Biochem J
Title: Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation.
Volume: 433
Issue: 1
Pages: 245-52
Publication
First Author: Zhao Y
Year: 2014
Journal: Mol Cell Biol
Title: p300-dependent acetylation of activating transcription factor 5 enhances C/EBPβ transactivation of C/EBPα during 3T3-L1 differentiation.
Volume: 34
Issue: 3
Pages: 315-24
Publication
First Author: Fang S
Year: 2008
Journal: J Biol Chem
Title: The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.
Volume: 283
Issue: 50
Pages: 35086-95
Publication
First Author: Xu W
Year: 1998
Journal: Mol Cell Biol
Title: Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates.
Volume: 18
Issue: 10
Pages: 5659-69
Publication
First Author: Mehra-Chaudhary R
Year: 2001
Journal: Biochem J
Title: Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter.
Volume: 353
Issue: Pt 1
Pages: 13-22
Publication
First Author: Cismasiu VB
Year: 2006
Journal: Blood
Title: BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes.
Volume: 108
Issue: 8
Pages: 2695-702
Publication
First Author: Lu Y
Year: 2013
Journal: J Clin Invest
Title: Kruppel-like factor 15 is critical for vascular inflammation.
Volume: 123
Issue: 10
Pages: 4232-41
Publication
First Author: Lee HK
Year: 2007
Journal: EMBO J
Title: MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.
Volume: 26
Issue: 15
Pages: 3545-57
Publication
First Author: Bouras T
Year: 2005
Journal: J Biol Chem
Title: SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.
Volume: 280
Issue: 11
Pages: 10264-76
Publication
First Author: Kuno A
Year: 2013
Journal: J Biol Chem
Title: Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein.
Volume: 288
Issue: 8
Pages: 5963-72
Publication
First Author: Tollini LA
Year: 2014
Journal: Cancer Cell
Title: Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage.
Volume: 26
Issue: 2
Pages: 235-47
Publication
First Author: Fukuyama T
Year: 2009
Journal: Mol Cell Biol
Title: Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development.
Volume: 29
Issue: 14
Pages: 3894-904
Publication
First Author: Bragança J
Year: 2003
Journal: J Biol Chem
Title: Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.
Volume: 278
Issue: 18
Pages: 16021-9
Publication
First Author: Sauer M
Year: 2017
Journal: Oncogene
Title: CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells.
Volume: 36
Issue: 7
Pages: 933-941
Publication
First Author: Tikhanovich I
Year: 2017
Journal: J Biol Chem
Title: Arginine methylation regulates c-Myc-dependent transcription by altering promoter recruitment of the acetyltransferase p300.
Volume: 292
Issue: 32
Pages: 13333-13344
Publication
First Author: Xu W
Year: 2007
Journal: EMBO J
Title: Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms.
Volume: 26
Issue: 12
Pages: 2890-903
Publication
First Author: Kasper LH
Year: 2005
Journal: EMBO J
Title: Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.
Volume: 24
Issue: 22
Pages: 3846-58
Publication
First Author: Zocchi L
Year: 2012
Journal: Epigenetics
Title: SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression.
Volume: 7
Issue: 7
Pages: 695-700
Publication
First Author: Yoshida H
Year: 2007
Journal: Mol Cell Biol
Title: PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation.
Volume: 27
Issue: 16
Pages: 5819-34
Publication
First Author: Kong S
Year: 2011
Journal: J Biol Chem
Title: The type III histone deacetylase Sirt1 protein suppresses p300-mediated histone H3 lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation.
Volume: 286
Issue: 19
Pages: 16967-75
Publication
First Author: Kasper LH
Year: 2002
Journal: Nature
Title: A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.
Volume: 419
Issue: 6908
Pages: 738-43
Publication
First Author: Shen Y
Year: 2007
Journal: J Biol Chem
Title: Functional architecture of atrophins.
Volume: 282
Issue: 7
Pages: 5037-44
Publication
First Author: Pentz ES
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Histone acetyl transferases CBP and p300 are necessary for maintenance of renin cell identity and transformation of smooth muscle cells to the renin phenotype.
Volume: 302
Issue: 12
Pages: H2545-52
Publication
First Author: Gomez RA
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.
Volume: 296
Issue: 5
Pages: H1255-62
Publication
First Author: Carré GA
Year: 2018
Journal: Hum Mol Genet
Title: Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.
Volume: 27
Issue: 1
Pages: 190-198
Publication
First Author: Liu Y
Year: 2014
Journal: Mol Cell Biol
Title: Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function.
Volume: 34
Issue: 21
Pages: 3993-4007
Publication
First Author: Kasper LH
Year: 2013
Journal: PLoS One
Title: Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
Volume: 8
Issue: 12
Pages: e82684
Publication
First Author: Lin Z
Year: 2016
Journal: Dev Cell
Title: Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth.
Volume: 39
Issue: 4
Pages: 466-479
Publication
First Author: Ji Q
Year: 2019
Journal: Nat Commun
Title: Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis.
Volume: 10
Issue: 1
Pages: 313
Publication
First Author: He L
Year: 2012
Journal: J Biol Chem
Title: Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis.
Volume: 287
Issue: 38
Pages: 32069-77
Publication
First Author: Molinari S
Year: 2004
Journal: Mol Cell Biol
Title: A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300.
Volume: 24
Issue: 7
Pages: 2944-57
Publication
First Author: Lill NL
Year: 1997
Journal: Nature
Title: Binding and modulation of p53 by p300/CBP coactivators.
Volume: 387
Issue: 6635
Pages: 823-7
Publication
First Author: Furumatsu T
Year: 2010
Journal: Int J Biochem Cell Biol
Title: Scleraxis and E47 cooperatively regulate the Sox9-dependent transcription.
Volume: 42
Issue: 1
Pages: 148-56
Publication
First Author: Song L
Year: 2011
Journal: Oncogene
Title: p85α mediates p53 K370 acetylation by p300 and regulates its promoter-specific transactivity in the cellular UVB response.
Volume: 30
Issue: 11
Pages: 1360-71
Publication
First Author: Motta MC
Year: 2004
Journal: Cell
Title: Mammalian SIRT1 represses forkhead transcription factors.
Volume: 116
Issue: 4
Pages: 551-63
Publication
First Author: Sánchez-Molina S
Year: 2006
Journal: Biochem J
Title: The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway.
Volume: 398
Issue: 2
Pages: 215-24
Publication
First Author: Tu AW
Year: 2007
Journal: J Biol Chem
Title: Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response.
Volume: 282
Issue: 29
Pages: 21187-96
Publication
First Author: Li Y
Year: 2008
Journal: Mol Cell Biol
Title: Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1.
Volume: 28
Issue: 13
Pages: 4275-84
Publication
First Author: Seo GY
Year: 2009
Journal: Eur J Immunol
Title: Analyses of TGF-beta1-inducible Ig germ-line gamma2b promoter activity: involvement of Smads and NF-kappaB.
Volume: 39
Issue: 4
Pages: 1157-66
Publication
First Author: Tsuruyama T
Year: 2011
Journal: Am J Pathol
Title: Murine leukemia retrovirus integration induces the formation of transcription factor complexes on palindromic sequences in the signal transducer and activator of transcription factor 5a gene during the development of pre-B lymphomagenesis.
Volume: 178
Issue: 3
Pages: 1374-86
Publication
First Author: Kamiya D
Year: 2011
Journal: Nature
Title: Intrinsic transition of embryonic stem-cell differentiation into neural progenitors.
Volume: 470
Issue: 7335
Pages: 503-9