Type |
Details |
Score |
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
579
 |
Fragment?: |
false |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
436 |
Description: |
Phosphoserine; by FAM20C |
Type: |
modified residue |
End: |
436 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
203
 |
Fragment?: |
false |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
88 |
Description: |
Extracellular serine/threonine protein kinase FAM20C |
Type: |
chain |
End: |
579 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization. |
Volume: |
118 |
Issue: |
32 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pollak AJ |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. |
Volume: |
114 |
Issue: |
34 |
Pages: |
9098-9103 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ben Djoudi Ouadda A |
Year: |
2019 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor). |
Volume: |
39 |
Issue: |
10 |
Pages: |
1996-2013 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao J |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Crystal structure of the Golgi casein kinase. |
Volume: |
110 |
Issue: |
26 |
Pages: |
10574-9 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the C-terminal of the eukaryotic secreted Golgi casein kinase protein FAM20C. FAM20C is the Golgi casein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs. Mutations in the FAM20C gene cause Raine syndrome, an autosomal recessive osteosclerotic bone dysplasia []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
541
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Koike T |
Year: |
2009 |
Journal: |
Biochem J |
Title: |
FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region. |
Volume: |
421 |
Issue: |
2 |
Pages: |
157-62 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
FAM20 is a family of secreted proteins with a potential role in regulating differentiation and function of hematopoietic and other tissues. Proteins in this family include FAM20A [], FAM20B or glycosaminoglycan xylosylkinase [], and FAM20C or dentin matrix protein 4 [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Mobley CG |
Year: |
2015 |
Journal: |
J Dent Res |
Title: |
Dspp-independent Effects of Transgenic Trps1 Overexpression on Dentin Formation. |
Volume: |
94 |
Issue: |
8 |
Pages: |
1128-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma P |
Year: |
2016 |
Journal: |
J Dent Res |
Title: |
The Importance of Serine Phosphorylation of Ameloblastin on Enamel Formation. |
Volume: |
95 |
Issue: |
12 |
Pages: |
1408-1414 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu J |
Year: |
2020 |
Journal: |
EMBO J |
Title: |
Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress. |
Volume: |
39 |
Issue: |
10 |
Pages: |
e103841 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li L |
Year: |
2019 |
Journal: |
J Mol Histol |
Title: |
FAM20A is essential for amelogenesis, but is dispensable for dentinogenesis. |
Volume: |
50 |
Issue: |
6 |
Pages: |
581-591 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan WJ |
Year: |
2017 |
Journal: |
Int J Oral Sci |
Title: |
The importance of a potential phosphorylation site in enamelin on enamel formation. |
Volume: |
9 |
Issue: |
11 |
Pages: |
e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dzamukova M |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth. |
Volume: |
13 |
Issue: |
1 |
Pages: |
3059 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zelenchuk LV |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism. |
Volume: |
9 |
Issue: |
5 |
Pages: |
e97326 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dong C |
Year: |
2022 |
Journal: |
Matrix Biol |
Title: |
The phosphorylation of serine(55) in enamelin is essential for murine amelogenesis. |
Volume: |
111 |
|
Pages: |
245-263 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
|
•
•
•
•
•
|