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Search results 301 to 352 out of 352 for Fgr

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0.042s

Type

Details

Score

Allele

Fgr<Gt(IST14975A2)Tigm> | MGI:5273132

Name:	FGR proto-oncogene, Src family tyrosine kinase; gene trap IST14975A2, Texas A&M Institute for Genomic Medicine
Allele Type:	Gene trapped

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Strain

MGI:7853131 | C57BL/6NCrl-Fgr<em1(IMPC)Ccpcz>/Ph

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:7591106 | C57BL/6J-Fgr<em1Cya>/Cya

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Strain

MGI:7588387 | C57BL/6J-Fgr<em2Cya>/Cya

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Genotype

Symbol:	Fgr/Fgr<+>
Background:	C3HeB/FeJ-Fgr
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Fgr/Fgr<+>
Background:	either: (involves: BALB/c * C3HeB/FeJ) or (involves: C3HeB/FeJ * C57BL/6J) or (involves: C3HeB/FeJ * CAST/EiJ)
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Fgr/Fgr
Background:	involves: 129S7/SvEvBrd * C57BL/6
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Fgr/Fgr
Background:	B6.129S7-Fgr
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Fgr/Fgr
Background:	involves: 129S7/SvEvBrd * C57BL/6J
Zygosity:	hm
Has Mutant Allele:	true

•

Publication

16684964 | -

First Author:	Heiss E
Year:	2006
Journal:	Blood
Title:	Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.
Volume:	108
Issue:	5
Pages:	1542-50

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Publication

10066823 | -

First Author:	Brunati AM
Year:	1999
Journal:	J Biol Chem
Title:	Molecular features underlying the sequential phosphorylation of HS1 protein and its association with c-Fgr protein-tyrosine kinase.
Volume:	274
Issue:	11
Pages:	7557-64

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Protein Domain

IPR035693 | Fgr_SH2

Type:

Domain

Description:

Tyrosine-protein kinase Fgr belongs to the SRC family of the Tyr protein kinases. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune responses, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration [, , ]. It contains a protein kinase domain, an SH2 domain and an SH3 domain. Fgr interacts with tyrosine phosphorylated SYK, FLT3 and HCLS1 via its SH2 domain [].This entry represents the SH2 domain of Fgr.

•

Genotype

Symbol:	Fgr/Fgr Hck/Hck
Background:	involves: 129S7/SvEvBrd * C57BL/6J
Zygosity:	cx
Has Mutant Allele:	true

•

Strain

MGI:3785472 | B6.Cg-Hck<tm1Hev> Fgr<tm1Hev> Lyn<tm1Sor>

Attribute String:

congenic, targeted mutation

•

Genotype

Symbol:	Fgr/Fgr Hck/Hck Lyn/Lyn
Background:	B6.Cg-Hck Fgr Lyn
Zygosity:	cx
Has Mutant Allele:	true

•

HT Experiment

E-MTAB-6945 | Single-cell analysis of T-cells from mouse neonate thymuses in a wild type control and a placental specific isoform of Igf2 knock-down (igf2-P0)


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	ArrayExpress

•

Publication

8694808 | J:34080

First Author:	Hamaguchi I
Year:	1996
Journal:	Biochem Biophys Res Commun
Title:	Analysis of CSK homologous kinase (CHK/HYL) in hematopoiesis by utilizing gene knockout mice.
Volume:	224
Issue:	1
Pages:	172-9

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Publication

25783157 | J:260396

First Author:	Kim HS
Year:	2015
Journal:	Sci Signal
Title:	Interleukin-10-producing CD5+ B cells inhibit mast cells during immunoglobulin E-mediated allergic responses.
Volume:	8
Issue:	368
Pages:	ra28

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Publication

23896410 | J:202360

First Author:	Dos Santos C
Year:	2013
Journal:	Blood
Title:	The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents.
Volume:	122
Issue:	11
Pages:	1900-13

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Publication

22078799 | J:178830

First Author:	Zhu JW
Year:	2011
Journal:	Immunity
Title:	Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus.
Volume:	35
Issue:	5
Pages:	757-69

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Publication

19520061 | J:150651

First Author:	Numazaki M
Year:	2009
Journal:	Biochem Biophys Res Commun
Title:	Cross-linking of SIGNR1 activates JNK and induces TNF-alpha production in RAW264.7 cells that express SIGNR1.
Volume:	386
Issue:	1
Pages:	202-6

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Publication

35906236 | J:327112

First Author:	Kaur G
Year:	2022
Journal:	Nat Commun
Title:	Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.
Volume:	13
Issue:	1
Pages:	4398

•

Publication

30158878 | J:276427

First Author:	Renshall LJ
Year:	2018
Journal:	Front Physiol
Title:	Melatonin Increases Fetal Weight in Wild-Type Mice but Not in Mouse Models of Fetal Growth Restriction.
Volume:	9

Pages:	1141

•

Publication

23667712 | J:200530

First Author:	Poudel R
Year:	2013
Journal:	PLoS One
Title:	Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus.
Volume:	8
Issue:	5
Pages:	e64401

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Publication

34019873 | J:306285

First Author:	Matsubara T
Year:	2021
Journal:	J Biol Chem
Title:	Characterization of unique functionalities in c-Src domains required for osteoclast podosome belt formation.


Pages:	100790

•

Publication

23509372 | J:197922

First Author:	Thaete LG
Year:	2013
Journal:	Reproduction
Title:	Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice.
Volume:	145
Issue:	5
Pages:	517-26

•

Publication

16981008 | J:114553

First Author:	Li M
Year:	2006
Journal:	J Clin Invest
Title:	Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice.
Volume:	116
Issue:	10
Pages:	2653-62

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Publication

32703931 | J:305750

First Author:	Freitag N
Year:	2020
Journal:	Cell Death Dis
Title:	Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency.
Volume:	11
Issue:	7
Pages:	560

•

Publication

34987220 | J:338100

First Author:	Crainiciuc G
Year:	2022
Journal:	Nature
Title:	Behavioural immune landscapes of inflammation.
Volume:	601
Issue:	7893
Pages:	415-421

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Publication

37541847 | J:338938

First Author:	Kobayashi K
Year:	2023
Journal:	Life Sci Alliance
Title:	Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.
Volume:	6
Issue:	10

•

Publication

34186168 | J:310865

First Author:	Merech F
Year:	2021
Journal:	Biochim Biophys Acta Mol Basis Dis
Title:	Growth impairment, increased placental glucose uptake and altered transplacental transport in VIP deficient pregnancies: Maternal vs. placental contributions.
Volume:	1867
Issue:	10
Pages:	166207

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Publication

16293667 | J:108414

First Author:	Watson CS
Year:	2006
Journal:	Endocrinology
Title:	Elevated circulating insulin-like growth factor binding protein-1 is sufficient to cause fetal growth restriction.
Volume:	147
Issue:	3
Pages:	1175-86

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Publication

10776798 | J:118309

First Author:	Ato M
Year:	2000
Journal:	Immunobiology
Title:	Delayed clearance of zymosan-induced granuloma and depressed phagocytosis of macrophages with concomitant up-regulated kinase activities of Src-family in a human monocyte chemoattractant protein-1 transgenic mouse.
Volume:	201
Issue:	3-4
Pages:	432-49

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Publication

31932454 | J:285799

First Author:	Asem M
Year:	2020
Journal:	Cancer Res
Title:	Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis.
Volume:	80
Issue:	5
Pages:	1156-1170

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Publication

38396719 | J:345964

First Author:	Vogtmann R
Year:	2024
Journal:	Int J Mol Sci
Title:	Overexpression of Human sFLT1 in the Spongiotrophoblast Is Sufficient to Induce Placental Dysfunction and Fetal Growth Restriction in Transgenic Mice.
Volume:	25
Issue:	4

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Publication

27821757 | J:238841

First Author:	Li F
Year:	2016
Journal:	Proc Natl Acad Sci U S A
Title:	Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia.
Volume:	113
Issue:	47
Pages:	13450-13455

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Publication

19307307 | J:149152

First Author:	Seo JH
Year:	2009
Journal:	Mol Cell Biol
Title:	Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop.
Volume:	29
Issue:	11
Pages:	3076-87

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Publication

34406367 | J:326024

First Author:	Vaughan OR
Year:	2021
Journal:	Clin Sci (Lond)
Title:	Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice.
Volume:	135
Issue:	17
Pages:	2049-2066

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Publication

8000137 | J:20128

First Author:	Beever JE
Year:	1994
Journal:	Mamm Genome
Title:	A genetic map of nine loci on bovine chromosome 2.
Volume:	5
Issue:	9
Pages:	542-5

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Publication

15869794 | J:104849

First Author:	Leu TH
Year:	2006
Journal:	Mol Immunol
Title:	Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages.
Volume:	43
Issue:	4
Pages:	308-16

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Publication

31703840 | J:292137

First Author:	Sekimoto A
Year:	2020
Journal:	Biochem Biophys Res Commun
Title:	Tadalafil alleviates preeclampsia and fetal growth restriction in RUPP model of preeclampsia in mice.
Volume:	521
Issue:	3
Pages:	769-774

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Publication

33621475 | J:303930

First Author:	Wilson RL
Year:	2021
Journal:	Am J Physiol Regul Integr Comp Physiol
Title:	Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth.
Volume:	320
Issue:	5
Pages:	R653-R662

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Publication

30443254 | J:356073

First Author:	Bacon WA
Year:	2018
Journal:	Front Immunol
Title:	Single-Cell Analysis Identifies Thymic Maturation Delay in Growth-Restricted Neonatal Mice.
Volume:	9

Pages:	2523

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Publication

22552791 | J:190504

First Author:	Kusinski LC
Year:	2012
Journal:	Am J Physiol Regul Integr Comp Physiol
Title:	eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype.
Volume:	303
Issue:	1
Pages:	R86-93

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Publication

24204949 | J:209249

First Author:	Dilworth MR
Year:	2013
Journal:	PLoS One
Title:	Sildenafil citrate increases fetal weight in a mouse model of fetal growth restriction with a normal vascular phenotype.
Volume:	8
Issue:	10
Pages:	e77748

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Publication

24226519 | J:205119

First Author:	Rieg T
Year:	2014
Journal:	Am J Physiol Renal Physiol
Title:	Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.
Volume:	306
Issue:	2
Pages:	F188-93

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Publication

26530156 | J:235822

First Author:	Charnock JC
Year:	2016
Journal:	Am J Physiol Endocrinol Metab
Title:	The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction.
Volume:	310
Issue:	1
Pages:	E24-31

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Publication

32203108 | J:356096

First Author:	de Barros Mucci D
Year:	2020
Journal:	Int J Obes (Lond)
Title:	Impact of maternal obesity on placental transcriptome and morphology associated with fetal growth restriction in mice.
Volume:	44
Issue:	5
Pages:	1087-1096

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Protein

Q6GTF2

Organism:	Mus musculus/domesticus
Length:	517
Fragment?:	false

•

Publication

19144319 | J:143718

First Author:	Trost M
Year:	2009
Journal:	Immunity
Title:	The phagosomal proteome in interferon-gamma-activated macrophages.
Volume:	30
Issue:	1
Pages:	143-54

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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