Type |
Details |
Score |
Publication |
First Author: |
Duong HA |
Year: |
2011 |
Journal: |
Science |
Title: |
A molecular mechanism for circadian clock negative feedback. |
Volume: |
332 |
Issue: |
6036 |
Pages: |
1436-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao G |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1. |
Volume: |
12 |
Issue: |
5 |
Pages: |
1165-72 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Sin3a is a transcriptional repressor and a homologue of the SIN3 repressor from yeast. Sin3a associates with the strong repressive isoform of Mxi1, a helix-loop-helix leucone zipper that associates with Max to antagonize Myc oncogenic activities []. Unlike Mxi1 and Myc, expression of Sin3a does not vary during development []. Sin3a is a component of several complexes, including the REST-CoREST repressor complex [], the PER complex which maintains circadian rhythm []and the Sin3 HDAC complex []. Sin3a also interacts with FOXK1 to regulate cell cycle progression []. Sin3a has three PAH domains by which it interacts with HCFC1, REST and SAP30 [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian M |
Year: |
2023 |
Journal: |
iScience |
Title: |
JLP/Foxk1/N-cadherin axis fosters a partial epithelial-mesenchymal transition state in epithelial tubular cells. |
Volume: |
26 |
Issue: |
4 |
Pages: |
106396 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2015 |
Journal: |
Dev Cell |
Title: |
FOXKs promote Wnt/β-catenin signaling by translocating DVL into the nucleus. |
Volume: |
32 |
Issue: |
6 |
Pages: |
707-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramkumar P |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
JNK-associated Leucine Zipper Protein Functions as a Docking Platform for Polo-like Kinase 1 and Regulation of the Associating Transcription Factor Forkhead Box Protein K1. |
Volume: |
290 |
Issue: |
49 |
Pages: |
29617-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fleischer TC |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Identification and characterization of three new components of the mSin3A corepressor complex. |
Volume: |
23 |
Issue: |
10 |
Pages: |
3456-67 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1274
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|