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Search results 301 to 400 out of 1143 for Gla

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Type Details Score
Publication
9196009 | J:41356
First Author: Lyu MS
Year: 1997
Journal: Mamm Genome
Title: Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.
Volume: 8
Issue: 7
Pages: 541
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Publication
17942075 | J:127430
First Author: Li Q
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Pseudoxanthoma elasticum: reduced gamma-glutamyl carboxylation of matrix gla protein in a mouse model (Abcc6-/-).
Volume: 364
Issue: 2
Pages: 208-13
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Publication
15539565 | J:323372
First Author: Zhou D
Year: 2004
Journal: Science
Title: Lysosomal glycosphingolipid recognition by NKT cells.
Volume: 306
Issue: 5702
Pages: 1786-9
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Publication
15820316 | J:97549
First Author: Sasaki M
Year: 2005
Journal: Genomics
Title: Molecular cloning and functional characterization of mouse Nxf family gene products.
Volume: 85
Issue: 5
Pages: 641-53
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Publication
16982810 | J:124639
First Author: Gadola SD
Year: 2006
Journal: J Exp Med
Title: Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
Volume: 203
Issue: 10
Pages: 2293-303
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Publication
22875802 | J:189359
First Author: Porubsky S
Year: 2012
Journal: J Immunol
Title: Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.
Volume: 189
Issue: 6
Pages: 3007-17
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Publication
2906327 | J:9627
First Author: Mullins LJ
Year: 1988
Journal: Genomics
Title: Multilocus molecular mapping of the mouse X chromosome.
Volume: 3
Issue: 3
Pages: 187-94
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Publication
205481 | J:5963
First Author: Lusis AJ
Year: 1978
Journal: Genetics
Title: X-linked and autosomal genes controlling mouse alpha-galactosidase expression.
Volume: 88
Issue: 2
Pages: 327-42
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Publication
2890215 | J:8903
First Author: Chamberlain JS
Year: 1987
Journal: Somat Cell Mol Genet
Title: Regional localization of the murine Duchenne muscular dystrophy gene on the mouse X chromosome.
Volume: 13
Issue: 6
Pages: 671-8
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Publication
3416629 | J:9340
 
First Author: Stephenson DA
Year: 1988
Journal: Curr Top Microbiol Immunol
Title: X-chromosome gene order in different Mus species crosses.
Volume: 137
Pages: 18-24
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Publication
2571569 | J:10029
First Author: Disteche CM
Year: 1989
Journal: Genomics
Title: Comparison of the physical and recombination maps of the mouse X chromosome.
Volume: 5
Issue: 2
Pages: 177-84
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Publication
1973136 | J:10593
First Author: Herman GE
Year: 1990
Journal: Genomics
Title: Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.
Volume: 7
Issue: 3
Pages: 307-12
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Publication
1675194 | J:11234
First Author: Chapman VM
Year: 1991
Journal: Genomics
Title: Linkage of amelogenin (Amel) to the distal portion of the mouse X chromosome.
Volume: 10
Issue: 1
Pages: 23-8
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Publication
19710420 | J:164482
First Author: Boonen M
Year: 2009
Journal: Mol Biol Cell
Title: Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity.
Volume: 20
Issue: 20
Pages: 4381-9
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Publication
1235912 | J:5817
First Author: Kozak C
Year: 1975
Journal: Somatic Cell Genet
Title: Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome.
Volume: 1
Issue: 4
Pages: 371-82
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Publication
2110546 | J:10474
First Author: Mullins LJ
Year: 1990
Journal: Genomics
Title: Efficient linkage of 10 loci in the proximal region of the mouse X chromosome.
Volume: 7
Issue: 1
Pages: 19-30
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Publication
1964443 | J:11078
First Author: Chapman VM
Year: 1990
Journal: Genomics
Title: Linkage of a gene for neural cell adhesion molecule, L1 (CamL1) to the Rsvp region of the mouse X chromosome.
Volume: 8
Issue: 1
Pages: 113-8
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Publication
1674728 | J:11194
First Author: Herman GE
Year: 1991
Journal: Genomics
Title: Genetic mapping of the mouse X chromosome in the region homologous to human Xq27-Xq28.
Volume: 9
Issue: 4
Pages: 670-7
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Publication
19661459 | J:169973
First Author: Yao Y
Year: 2009
Journal: Circ Res
Title: Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein.
Volume: 105
Issue: 6
Pages: 575-84
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Publication
18425126 | J:142334
First Author: Blewitt ME
Year: 2008
Journal: Nat Genet
Title: SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.
Volume: 40
Issue: 5
Pages: 663-9
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Publication
198184 | J:5872
First Author: Francke U
Year: 1977
Journal: Cytogenet Cell Genet
Title: Gene mapping in Mus musculus by interspecific cell hybridization: assignment of the genes for tripeptidase-1 to chromosome 10, dipeptidase-2 to chromosome 18, acid phosphatase-1 to chromosome 12, and adenylate kinase-1 to chromosome 2.
Volume: 19
Issue: 2-3
Pages: 57-84
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
23754746 | J:204566
First Author: Gendrel AV
Year: 2013
Journal: Mol Cell Biol
Title: Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.
Volume: 33
Issue: 16
Pages: 3150-65
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Protein
P86546
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: false
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Protein
P86547
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: false
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Protein Coding Gene
MGI:96976 | Mgp
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
28245920 | J:240028
First Author: Bulusu V
Year: 2017
Journal: Dev Cell
Title: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Volume: 40
Issue: 4
Pages: 331-341.e4
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
9434150 | J:44881
First Author: Wiedemann M
Year: 1998
Journal: Biochim Biophys Acta
Title: Molecular cloning of avian matrix Gla protein.
Volume: 1395
Issue: 1
Pages: 47-9
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Gene
25333 | Mgp
Type: gene
Organism: rat
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Gene
465310 | MGP
Type: gene
Organism: chimpanzee
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Gene
100856382 | MGP
Type: gene
Organism: dog, domestic
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Gene
395912 | MGP
Type: gene
Organism: chicken
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Gene
402937 | mgp
Type: gene
Organism: zebrafish
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Gene
574116 | MGP
Type: gene
Organism: macaque, rhesus
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Gene
100493712 | mgp
Type: gene
Organism: frog, western clawed
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Gene
282660 | MGP
Type: gene
Organism: cattle
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Publication
24098781 | J:205998
First Author: Beazley KE
Year: 2013
Journal: PLoS One
Title: Attenuation of chondrogenic transformation in vascular smooth muscle by dietary quercetin in the MGP-deficient mouse model.
Volume: 8
Issue: 9
Pages: e76210
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Publication
11739279 | J:115414
First Author: Steitz SA
Year: 2001
Journal: Circ Res
Title: Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers.
Volume: 89
Issue: 12
Pages: 1147-54
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Publication
29217507 | J:284963
First Author: Gourgas O
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Multidisciplinary Approach to Understand Medial Arterial Calcification.
Volume: 38
Issue: 2
Pages: 363-372
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Publication
17670744 | J:126724
First Author: Yao Y
Year: 2007
Journal: J Biol Chem
Title: Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development.
Volume: 282
Issue: 41
Pages: 30131-42
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UniProt Feature
UniProt Feature
Begin: 20
Description: Matrix Gla protein
Type: chain
End: 104
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UniProt Feature
UniProt Feature
Begin: 20
Description: Matrix Gla protein
Type: chain
End: 104
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UniProt Feature
UniProt Feature
Begin: 18
Description: Gla domain-containing protein
Type: chain
End: 226
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UniProt Feature
UniProt Feature
Begin: 20
Description: Matrix Gla protein
Type: chain
End: 104
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Protein
Q6PAQ9
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: false
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Protein
Q8BGN6
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: false
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Protein
Q8R182
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Publication
12193585 | J:81457
First Author: Donohue MM
Year: 2002
Journal: Endocrinology
Title: Rickets in VDR null mice is secondary to decreased apoptosis of hypertrophic chondrocytes.
Volume: 143
Issue: 9
Pages: 3691-4
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Protein Coding Gene
MGI:1917364 | Prrg1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29392320 | J:256962
First Author: Asokan P
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies.
Volume: 59
Issue: 2
Pages: 746-756
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Protein Coding Gene
MGI:2442211 | Prrg4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2685214 | Prrg3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
3317405 | -
First Author: Price PA
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase.
Volume: 84
Issue: 23
Pages: 8335-9
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Publication
23994172 | J:203924
First Author: Marulanda J
Year: 2013
Journal: Bone
Title: Prevention of arterial calcification corrects the low bone mass phenotype in MGP-deficient mice.
Volume: 57
Issue: 2
Pages: 499-508
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Gene
108715107 | mgp.S
Type: gene
Organism: frog, African clawed
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Gene
373621 | mgp.L
Type: gene
Organism: frog, African clawed
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Publication
19197075 | J:285562
First Author: Speer MY
Year: 2009
Journal: Circ Res
Title: Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries.
Volume: 104
Issue: 6
Pages: 733-41
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Protein Domain
IPR027118 | MGP
Type: Family
Description: Matrix Gla protein associates with the organic matrix of bone and cartilage. It is thought to act as an inhibitor of calcification []. Defects in MGP are the cause of Keutel syndrome (KS). KS is an autosomal recessive disorder characterised by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia [].
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Protein Domain
IPR017857 | Coagulation_fac-like_Gla_dom
Type: Homologous_superfamily
Description: This superfamily represents a structural domain with an irregular fold that is found in a subset of coagulation factors, where it forms part of the Gla region.The GLA (gamma-carboxyglutamic acid-rich) domain contains glutamate residues that have been post-translationally modified by vitamin K-dependent carboxylation to form gamma-carboxyglutamate (Gla) [, , ]. All glutamic acid (Glu) residues present in the GLA domain are potential carboxylation sites; in coagulation proteins, all Gu residues are modified to Gla, while in osteocalcin and matrix Gla proteins only some Glu residues are modified to Gla. The GLA domain is responsible for the high-affinity binding of calcium ions. It starts at the N-terminal extremity of the mature form of proteins and ends with a conserved aromatic residue; a conserved Gla-x(3)-Gla-x-Cys motif []is found in the middle of the domain which seems to be important for substrate recognition by the carboxylase.The 3D structure of the GLA domain has been solved [, ]. Calcium ions induce conformational changes in the GLA domain that and are necessary for the proper folding of the GLA domain. A common structural feature of functional GLA domains is the clustering of N-terminal hydrophobic residues into a hydrophobic patch that mediates interaction with the cell surface membrane [].
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Protein Coding Gene
MGI:1929596 | Prrg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15184399 | J:335627
First Author: Murshed M
Year: 2004
Journal: J Cell Biol
Title: Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins.
Volume: 165
Issue: 5
Pages: 625-30
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Protein Domain
IPR002384 | Osteocalcin/MGP
Type: Family
Description: Bone gamma-carboxyglutamic acid protein (BGP), also known as osteocalcin, and matrix gamma-carboxyglutamic acid protein (MGP) are the only vitamin K-dependent proteins that have been isolated from bone. MGP is a small protein found in bone, dentin and cartilage. It contains five gamma-carboxyglutamic acid (Gla) residues (formed by post-translational modification of glutamic acid by vitamin K-dependent carboxylase) and a single disulphide bond. BGP is a 49 residue protein found in bone. It contains three Gla residues and a single disulphide bond. There is little similarity between these vitamin K-dependent bone proteins and the blood coagulation proteins, though they are believed to have diverged from a common ancestor [].
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Publication
31659325 | J:282483
First Author: Malhotra R
Year: 2019
Journal: Nat Genet
Title: HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.
Volume: 51
Issue: 11
Pages: 1580-1587
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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