|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 405 for Gnaq

0.039s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Rambhatla L
Year: 1995
Journal: Mol Reprod Dev
Title: Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach.
Volume: 41
Issue: 3
Pages: 314-24
Publication
First Author: Jiang Z
Year: 2018
Journal: Cell
Title: Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.
Volume: 175
Issue: 3
Pages: 652-664.e12
Publication
First Author: Lee MJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.
Volume: 102
Issue: 42
Pages: 15030-5
Publication
First Author: Williams CJ
Year: 1996
Journal: Mol Reprod Dev
Title: G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.
Volume: 44
Issue: 3
Pages: 315-23
Publication
First Author: Izquierdo-Villalba I
Year: 2024
Journal: Sci Signal
Title: A mammalian-specific Alex3/Gα(q) protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival.
Volume: 17
Issue: 822
Pages: eabq1007
Publication
First Author: Wilkie TM
Year: 1992
Journal: Nat Genet
Title: Evolution of the mammalian G protein alpha subunit multigene family.
Volume: 1
Issue: 2
Pages: 85-91
Publication
First Author: Bedogni F
Year: 2016
Journal: Cereb Cortex
Title: Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.
Volume: 26
Issue: 6
Pages: 2517-2529
Publication
First Author: McClive PJ
Year: 2003
Journal: Genesis
Title: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Volume: 37
Issue: 2
Pages: 84-90
Publication
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Feng X
Year: 2014
Journal: Cancer Cell
Title: Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.
Volume: 25
Issue: 6
Pages: 831-45
Allele
Name: guanine nucleotide binding protein, alpha q polypeptide; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
DO Term
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: transgene insertion 40, Gerald W Dorn II
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 25, Gerald W Dorn II
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Gerald W Dorn II
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Catherine D Van Raamsdonk
Allele Type: Targeted
Attribute String: Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence
Publication
First Author: Schrenk S
Year: 2023
Journal: Nat Commun
Title: MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ.
Volume: 14
Issue: 1
Pages: 1929
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Biolo A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate.
Volume: 106
Issue: 6
Pages: 1926-9
Publication  
First Author: Pavez-Giani MG
Year: 2021
Journal: Int J Mol Sci
Title: ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ.
Volume: 22
Issue: 9
Publication
First Author: Zwadlo C
Year: 2015
Journal: Circulation
Title: Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction.
Volume: 131
Issue: 12
Pages: 1071-81
Publication
First Author: Satoh M
Year: 2007
Journal: Circulation
Title: Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen.
Volume: 115
Issue: 25
Pages: 3197-204
Publication
First Author: Rogers JH
Year: 2001
Journal: J Mol Cell Cardiol
Title: RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice.
Volume: 33
Issue: 2
Pages: 209-18
Publication
First Author: Timofeyev V
Year: 2006
Journal: J Mol Cell Cardiol
Title: Cardiac-directed expression of adenylyl cyclase reverses electrical remodeling in cardiomyopathy.
Volume: 41
Issue: 1
Pages: 170-81
Publication
First Author: Roth DM
Year: 2002
Journal: Circulation
Title: Adenylyl cyclase increases survival in cardiomyopathy.
Volume: 105
Issue: 16
Pages: 1989-94
Publication
First Author: Roth DM
Year: 1999
Journal: Circulation
Title: Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy.
Volume: 99
Issue: 24
Pages: 3099-102
Publication
First Author: Yatani A
Year: 1999
Journal: J Mol Cell Cardiol
Title: Cardiac-specific overexpression of Galphaq alters excitation-contraction coupling in isolated cardiac myocytes.
Volume: 31
Issue: 7
Pages: 1327-36
Publication
First Author: Sakata Y
Year: 1998
Journal: Circulation
Title: Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing mice.
Volume: 97
Issue: 15
Pages: 1488-95
Publication
First Author: Adams JW
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure.
Volume: 95
Issue: 17
Pages: 10140-5
Publication
First Author: Yussman MG
Year: 2002
Journal: Nat Med
Title: Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy.
Volume: 8
Issue: 7
Pages: 725-30
Publication
First Author: Tao W
Year: 2012
Journal: J Mol Cell Cardiol
Title: Spatial variability in T-tubule and electrical remodeling of left ventricular epicardium in mouse hearts with transgenic Gαq overexpression-induced pathological hypertrophy.
Volume: 53
Issue: 3
Pages: 409-19
Publication
First Author: Sano M
Year: 2004
Journal: EMBO J
Title: Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure.
Volume: 23
Issue: 17
Pages: 3559-69
Publication
First Author: Matkovich SJ
Year: 2010
Journal: Circ Res
Title: Deep mRNA sequencing for in vivo functional analysis of cardiac transcriptional regulators: application to Galphaq.
Volume: 106
Issue: 9
Pages: 1459-67
Publication
First Author: Kooij V
Year: 2016
Journal: Cardiovasc Res
Title: Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy.
Volume: 110
Issue: 2
Pages: 238-48
Allele
Name: transgene insertion 7, Richard Z Lin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Genotype
Symbol: Tg(Myh6-Gnaq)25Gwd/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Gnaq)40Gwd/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Gnaq)#Gwd/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: C3FeJ.Cg-Gt(ROSA)26Sor
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Timofeyev V
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Disruption of adenylyl cyclase type V does not rescue the phenotype of cardiac-specific overexpression of Galphaq protein-induced cardiomyopathy.
Volume: 299
Issue: 5
Pages: H1459-67
Publication
First Author: Takimoto E
Year: 2009
Journal: J Clin Invest
Title: Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice.
Volume: 119
Issue: 2
Pages: 408-20
Publication
First Author: Keys JR
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac hypertrophy and altered beta-adrenergic signaling in transgenic mice that express the amino terminus of beta-ARK1.
Volume: 285
Issue: 5
Pages: H2201-11
Publication
First Author: Sheikh F
Year: 2008
Journal: J Clin Invest
Title: An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice.
Volume: 118
Issue: 12
Pages: 3870-80
Genotype
Symbol: Fhl1/? Tg(Myh6-Gnaq)25Gwd/?
Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Gnaq*Q209L/Esr1*)7Rzl/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Zhang YM
Year: 2006
Journal: FASEB J
Title: Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis.
Volume: 20
Issue: 7
Pages: 916-25
Publication
First Author: Shi J
Year: 2008
Journal: J Mol Cell Cardiol
Title: Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy.
Volume: 44
Issue: 3
Pages: 551-60
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Genotype
Symbol: Tg(Myh6-Gnaq)25Gwd/? Tg(Myh6-Gnaq)40Gwd/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Yu FX
Year: 2014
Journal: Cancer Cell
Title: Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP.
Volume: 25
Issue: 6
Pages: 822-30
Publication
First Author: Vaqué JP
Year: 2013
Journal: Mol Cell
Title: A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.
Volume: 49
Issue: 1
Pages: 94-108
Publication  
First Author: Sasai M
Year: 2021
Journal: J Exp Med
Title: Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
Volume: 218
Issue: 7
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Genotype
Symbol: Bnip3l/Bnip3l Tg(Myh6-Gnaq)#Gwd/?
Background: involves: 129 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Gnaq)#Gwd/? Tg(Myh6-tTA)55Rbns/? Tg(tetO-Bnip3l)1Gwd/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Dct-lacZ)A12Jkn/? Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor Tg(Dct-lacZ)A12Jkn Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Lange S
Year: 2016
Journal: Nat Commun
Title: MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy.
Volume: 7
Pages: 12120
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Dorn GW 2nd
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Low- and high-level transgenic expression of beta2-adrenergic receptors differentially affect cardiac hypertrophy and function in Galphaq-overexpressing mice.
Volume: 96
Issue: 11
Pages: 6400-5
Publication
First Author: Chen Y
Year: 2013
Journal: J Biol Chem
Title: A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor κB (NFκB)-mediated cardiac transcription.
Volume: 288
Issue: 22
Pages: 15455-65
Publication
First Author: Aronow BJ
Year: 2001
Journal: Physiol Genomics
Title: Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy.
Volume: 6
Issue: 1
Pages: 19-28
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: C3FeJ.Cg-Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor/Cvrk
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true