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Search results 301 to 400 out of 3463 for Grasp

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Hits by Pathway

Hits by Category

Type Details Score
Genotype
Genotype
Symbol: Bag3/Bag3<+>
Background: C57BL/6N-Bag3/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cachd1/Cachd1<+>
Background: C57BL/6NJ-Cachd1/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cacng7/Cacng7
Background: C57BL/6N-Cacng7/BayMmucd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Camsap1/Camsap1<+>
Background: C57BL/6NJ-Camsap1/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Car4/Car4<+>
Background: C57BL/6N-Car4/Ieg
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk19/Cdk19<+>
Background: C57BL/6NJ-Cdk19/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cited4/Cited4
Background: B6N(Cg)-Cited4/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cpn1/Cpn1
Background: B6N(Cg)-Cpn1/2J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dbn1/Dbn1<+>
Background: C57BL/6N-Dbn1/Ics
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dhx37/Dhx37<+>
Background: C57BL/6NJ-Dhx37/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lpar4/?
Background: C57BL/6N-Lpar4/J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mtmr12/Mtmr12
Background: C57BL/6N-Mtmr12/Ics
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nectin4/Nectin4<+>
Background: C57BL/6NJ-Nectin4/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfkbil1/Nfkbil1
Background: C57BL/6N-Nfkbil1/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Padi1/Padi1
Background: C57BL/6NJ-Padi1/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Phf7/Phf7
Background: C57BL/6N-Phf7/Kmpc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pla2g4e/Pla2g4e
Background: C57BL/6N-Pla2g4e/Bay
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Raver2/Raver2
Background: C57BL/6NJ-Raver2/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stx1a/Stx1a
Background: C57BL/6N-Stx1a/Bay
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmem67/Tmem67<+>
Background: C57BL/6NJ-Tmem67/Mmjax
Zygosity: ht
Has Mutant Allele: true
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Publication
21235525 | -
First Author: Vinke FP
Year: 2011
Journal: Biochem J
Title: The multiple facets of the Golgi reassembly stacking proteins.
Volume: 433
Issue: 3
Pages: 423-33
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Publication
27436376 | -
 
First Author: Mendes LF
Year: 2016
Journal: Sci Rep
Title: New structural insights into Golgi Reassembly and Stacking Protein (GRASP) in solution.
Volume: 6
Pages: 29976
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Publication
23940043 | -
First Author: Feng Y
Year: 2013
Journal: J Biol Chem
Title: Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 proteins.
Volume: 288
Issue: 39
Pages: 28418-27
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Protein Domain
IPR024958 | GRASP_PDZ
Type: Domain
Description: The Golgi apparatus is a highly dynamic organelle responsible for sorting out proteins and other biomolecules to the cell surface and to the extracellular milieu. The Golgi apparatus is comprised of flattened membrane-bound compartments called cisternae, which are apposed to one another to form a Golgi stack. The structural organization of the cisternae into stacks and their lateral connection, building the Golgi ribbon, requires a family of proteins called Golgi ReAssembly and Stacking Proteins (GRASP). Two homologues (GRASP55 and GRASP65) have been described in vertebrates and their functions have been associated to Golgi phosphorylation-regulated assembly/disassembly, protein secretion , Golgi remodeling in migrating cells, among others. There is only one gene for GRASP in lower eukaryotes. Essentially all GRASPs containa conserved N-terminal GRASP region, which comprises two tandem PDZ domains (PDZ1 and PDZ2), a classical protein-peptide interaction domain, and is responsible for GRASP homo-oligomerization and for the attachment to the Golgi membrane. The C-terminal half which is not conserved between species but is rich in proline and serines residues, as well as glutamine and asparagine residues [, , , ]. The GRASP-type PDZ domains adopt a canonical PDZ fold with a β-sandwich of five β-strands and two α-helices. The PDZ1 and PDZ2 domains are nearly superimposable. The peptide-binding pockets of both PDZ domains are formed by alpha2 and beta5. A typical ligand peptide is predicted to form antiparallel β-strand interactions with beta5 and insert hydrophobic side chains between alpha2 and beta5. The two PDZ domains cooperate to achieve dimerization and oligomerization. In the dimers the PDZ2 domains interact in a way that positions the peptide-binding pockets facing each other. In addition, the dimers are linked through interactions between the two C-terminal tails (CTs) of one dimer and two peptide-binding pockets of the PDZ1 domains in the next dimer [, ]. This entry represents the GRASP-type PDZ domain.
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Publication
21884936 | J:176213
First Author: Gee HY
Year: 2011
Journal: Cell
Title: Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway.
Volume: 146
Issue: 5
Pages: 746-60
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Publication
22653731 | J:229368
First Author: Janda CY
Year: 2012
Journal: Science
Title: Structural basis of Wnt recognition by Frizzled.
Volume: 337
Issue: 6090
Pages: 59-64
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Publication
25766237 | J:259312
First Author: Weber GF
Year: 2015
Journal: Science
Title: Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.
Volume: 347
Issue: 6227
Pages: 1260-5
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Publication
27575947 | J:248765
 
First Author: McMackin MZ
Year: 2017
Journal: Behav Brain Res
Title: Neurobehavioral deficits in the KIKO mouse model of Friedreich's ataxia.
Volume: 316
Pages: 183-188
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Publication
30122532 | J:277047
First Author: Graydon CW
Year: 2018
Journal: Curr Biol
Title: Synaptic Transfer between Rod and Cone Pathways Mediated by AII Amacrine Cells in the Mouse Retina.
Volume: 28
Issue: 17
Pages: 2739-2751.e3
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Publication
23583114 | J:325330
First Author: Bui TV
Year: 2013
Journal: Neuron
Title: Circuits for grasping: spinal dI3 interneurons mediate cutaneous control of motor behavior.
Volume: 78
Issue: 1
Pages: 191-204
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Publication
33472081 | J:304283
First Author: Lopez-Huerta VG
Year: 2021
Journal: Cell Rep
Title: Striatal bilateral control of skilled forelimb movement.
Volume: 34
Issue: 3
Pages: 108651
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Publication
33621216 | J:316868
 
First Author: Agelidis A
Year: 2021
Journal: JCI Insight
Title: Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival.
Volume: 6
Issue: 7
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Publication
22682003 | J:209254
First Author: Mohebiany AN
Year: 2013
Journal: FEBS J
Title: Receptor-type tyrosine phosphatase ligands: looking for the needle in the haystack.
Volume: 280
Issue: 2
Pages: 388-400
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Publication
29212659 | J:258243
First Author: Villeneuve J
Year: 2018
Journal: J Cell Biol
Title: Unconventional secretion of FABP4 by endosomes and secretory lysosomes.
Volume: 217
Issue: 2
Pages: 649-665
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Publication
38383468 | J:345595
First Author: Adem B
Year: 2024
Journal: Nat Commun
Title: Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma.
Volume: 15
Issue: 1
Pages: 1496
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Allele
Tm4sf5<em1(IMPC)Kmpc> | MGI:6156347
Name: transmembrane 4 superfamily member 5; endonuclease-mediated mutation 1, Korea Mouse Phenotyping Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Limd1<em1(IMPC)H> | MGI:6257579
Name: LIM domains containing 1; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Acox1<em1(IMPC)Bay> | MGI:7425487
Name: acyl-Coenzyme A oxidase 1, palmitoyl; endonuclease-mediated mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Coding Gene
MGI:3649135 | Gm7694
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1924093 | Dtl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914680 | 4921536K21Rik
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103209 | Slc17a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923883 | Lrmda
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1921500 | Stimate
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919641 | Cdkn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109573 | Tep1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1859320 | Zftraf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914708 | Ergic1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102744 | Nelfe
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1347468 | Foxb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1934928 | Dusp15
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2138982 | Znfx1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1918605 | Col24a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2444345 | Acnat2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915553 | Fam114a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929722 | Anapc5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2137681 | Sfxn5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1202710 | Art4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1932374 | Cacng7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1347092 | Zfp146
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1861899 | Htr3b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3780550 | Mthfsl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442104 | Ppp2r3a
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Fbn2<fp> | MGI:1935123
 
Name: fibrillin 2; fused phalanges
Allele Type: Spontaneous
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Heritable Phenotypic Marker
MGI:2651822 | nmf62
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Allele
Tardbp<Gt(RRB030)Byg> | MGI:4126090
Name: TAR DNA binding protein; gene trap RRB030, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Allele
Ccdc134<tm1a(KOMP)Wtsi> | MGI:4362536
Name: coiled-coil domain containing 134; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Setdb2<tm1a(KOMP)Wtsi> | MGI:4364322
Name: SET domain, bifurcated 2; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Tnfrsf1b<tm1a(EUCOMM)Wtsi> | MGI:4433096
Name: tumor necrosis factor receptor superfamily, member 1b; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Edc4<tm1a(EUCOMM)Wtsi> | MGI:4433903
Name: enhancer of mRNA decapping 4; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Pacs2<tm1a(EUCOMM)Hmgu> | MGI:4435377
Name: phosphofurin acidic cluster sorting protein 2; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Ndufa8<tm1a(EUCOMM)Hmgu> | MGI:4436517
Name: NADH:ubiquinone oxidoreductase subunit A8; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Dmgdh<tm1a(KOMP)Wtsi> | MGI:4451237
Name: dimethylglycine dehydrogenase precursor; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Smn1<tm1.1Dscd> | MGI:4836979
Name: survival motor neuron 1; targeted mutation 1.1, Dawn S Chandler
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Cd55b<tm1a(KOMP)Wtsi> | MGI:4868034
Name: CD55 molecule, decay accelerating factor for complement B; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Tnks2<tm1b(KOMP)Wtsi> | MGI:5473325
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Gena185 | MGI:5490352
 
Name: Genetics Harwell, 185
Allele Type: Chemically induced (ENU)
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Allele
Htr1d<tm1.1(KOMP)Vlcg> | MGI:5529062
Name: 5-hydroxytryptamine (serotonin) receptor 1D; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Aph1c<tm1b(KOMP)Wtsi> | MGI:5548561
Name: aph1 homolog C, gamma secretase subunit; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Rbmx<tm2b(KOMP)Wtsi> | MGI:5558151
Name: RNA binding motif protein, X chromosome; targeted mutation 2b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Chp2<tm1b(KOMP)Mbp> | MGI:5565261
Name: calcineurin-like EF hand protein 2; targeted mutation 1b, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Gjd4<tm1.1(KOMP)Vlcg> | MGI:5574610
Name: gap junction protein, delta 4; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Pde4c<tm1.1(KOMP)Wtsi> | MGI:5585589
Name: phosphodiesterase 4C, cAMP specific; targeted mutation 1.1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Dpf1<tm1.1(KOMP)Vlcg> | MGI:5614559
Name: double PHD fingers 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Spata7<tm1.1(KOMP)Vlcg> | MGI:5635367
Name: spermatogenesis associated 7; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tex29<tm1.1(KOMP)Vlcg> | MGI:5634807
Name: testis expressed 29; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Runx3<tm1b(KOMP)Wtsi> | MGI:5635287
Name: runt related transcription factor 3; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tafa1<tm1.1(KOMP)Vlcg> | MGI:5635076
Name: TAFA chemokine like family member 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Hhipl1<tm1b(KOMP)Wtsi> | MGI:5637060
Name: hedgehog interacting protein-like 1; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Gmnc<tm1b(KOMP)Wtsi> | MGI:5637172
Name: geminin coiled-coil domain containing; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Acadm<tm1b(EUCOMM)Hmgu> | MGI:5637194
Name: acyl-Coenzyme A dehydrogenase, medium chain; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Heritable Phenotypic Marker
MGI:5646404 | Rec9
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Allele
Sfxn1<tm1b(EUCOMM)Wtsi> | MGI:5660778
Name: sideroflexin 1; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Ccdc50<tm1b(EUCOMM)Hmgu> | MGI:5692675
Name: coiled-coil domain containing 50; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Armh4<em1(IMPC)H> | MGI:5749842
Name: armadillo-like helical domain containing 4; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
St6galnac3<em1(IMPC)J> | MGI:5763623
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Acot2<em1(IMPC)J> | MGI:5763009
Name: acyl-CoA thioesterase 2; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Col16a1<em1(IMPC)J> | MGI:5763667
Name: collagen, type XVI, alpha 1; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Slc25a46<em1(IMPC)J> | MGI:5790100
Name: solute carrier family 25, member 46; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
mpc121H | MGI:5791994
 
Name: muta-ped-c3pde 121, Harwell
Allele Type: Chemically induced (ENU)
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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