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Search results 301 to 400 out of 443 for Grip1

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Type Details Score
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_11
Specimen Label: euxassay_013593_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_12
Specimen Label: euxassay_013593_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_13
Specimen Label: euxassay_013593_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_14
Specimen Label: euxassay_013593_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_15
Specimen Label: euxassay_013593_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_16
Specimen Label: euxassay_013593_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_17
Specimen Label: euxassay_013593_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_18
Specimen Label: euxassay_013593_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_19
Specimen Label: euxassay_013593_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_20
Specimen Label: euxassay_013593_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_21
Specimen Label: euxassay_013593_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_22
Specimen Label: euxassay_013593_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_23
Specimen Label: euxassay_013593_23
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:4417774
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825237
Age: embryonic day 14.5
Image: euxassay_013593_24
Specimen Label: euxassay_013593_24
Detected: true
Specimen Num: 24
Strain
Attribute String: mutant strain, congenic, targeted mutation
Strain
Attribute String: mutant strain, targeted mutation, congenic
Genotype
Symbol: Gripap1/Gripap1
Background: B6.129-Gripap1
Zygosity: hm
Has Mutant Allele: true
Interaction Experiment
Description: Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.
Interaction Experiment
Description: A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Gripap1/Gripap1 Tg(Thy1-EGFP)MJrs/?
Background: involves: 129 * C57BL/6 * C57BL/6J * CBA
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Wu HY
Year: 2005
Journal: J Biol Chem
Title: Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.
Volume: 280
Issue: 5
Pages: 3129-37
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 1462  
Fragment?: false
DO Term
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele  
Name: Fras1 related extracellular matrix protein 2; myelencephalic blebs
Allele Type: Radiation induced
Allele  
Name: Fras1 related extracellular matrix protein 1; head blebs
Allele Type: Spontaneous
Allele
Name: Fraser extracellular matrix complex subunit 1; targeted mutation 1, George Chalepakis
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: glutamate receptor interacting protein 1; targeted mutation 1, Ralf H Adams
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: Fras1 related extracellular matrix protein 1; bfd
Allele Type: Chemically induced (ENU)
Allele  
Name: Fras1 related extracellular matrix protein 2; myencephalic blebs, University College of London
Allele Type: Spontaneous
Allele
Name: Fras1 related extracellular matrix protein 1; targeted mutation 1, Kiyotoshi Sekiguchi
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: Fras1 related extracellular matrix protein 2; no eyelid
Allele Type: Spontaneous
Allele  
Name: Fras1 related extracellular matrix protein 2; Bench to Bassinet Program (B2B/CVDC), mutation 1562 Cecilia Lo
Allele Type: Chemically induced (ENU)
Allele
Name: Fraser extracellular matrix complex subunit 1; blood filled blisters
Allele Type: Chemically induced (ENU)
Attribute String: Altered localization
Allele
Name: Fraser extracellular matrix complex subunit 1; rounded foot
Allele Type: Chemically induced (ENU)
Attribute String: Null/knockout
Allele
Name: Fras1 related extracellular matrix protein 3; endonuclease-mediated mutation 1, Institute for Microbial Diseases, Osaka University
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Wilkinson B
Year: 2019
Journal: Biol Psychiatry
Title: Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.
Volume: 85
Issue: 4
Pages: 305-316
Publication
First Author: Kim JH
Year: 2003
Journal: Mol Cell
Title: CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivators.
Volume: 12
Issue: 6
Pages: 1537-49
Protein Domain
Type: Domain
Description: Calcium-binding and coiled-coil domain-containing protein 1 (Calcoco1) from Mus musculus () binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1 (), and thus enhances transcriptional activation by a number of nuclear receptors. Calcoco1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele  
Name: Fraser extracellular matrix complex subunit 1; blebbed
Allele Type: Radiation induced
Allele  
Name: glutamate receptor interacting protein 1; eye blebs
Allele Type: Spontaneous
Allele  
Name: Fras1 related extracellular matrix protein 1; bat
Allele Type: Chemically induced (ENU)
Genotype
Symbol: Fras1/Fras1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Grip1/Grip1
Background: B6.129-Grip1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2
Background: involves: NMRI
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Fras1/Fras1 Frem2/Frem2
Background: involves: 101/H * C3H/HeH * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2
Background: involves: 129P2/OlaHsd * CD-1 * NMRI
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem1/Frem1
Background: involves: AKR/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Grip1/Grip1
Background: involves: ATEB/Le * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2
Background: STOCK Frem2/GrsrJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Fras1/Fras1
Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem2/Frem2
Background: C57BL/6J-Frem2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Fras1/Fras1
Background: involves: C57BL/6JAnu
Zygosity: hm
Has Mutant Allele: true
DO Term
Genotype
Symbol: Frem2/Frem2
Background: MY/HuLeJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Frem3/Frem3
Background: involves: C57BL/6NJcl * DBA/2NJcl
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Fras1/Fras1
Background: involves: C57BL/6J * FVB/NJ
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 633  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Fras1/Fras1
Background: involves: 101/H * C3H/HeH
Zygosity: hm
Has Mutant Allele: true
Protein Domain
Type: Family
Description: Glutamate receptor-interacting proteins (GRIPs) are multi-PDZ domain scaffolding proteins required for dendrite development. There are two members of the GRIP family: GRIP1 and GRIP2/ABP (AMPA receptor binding protein) []. GRIPs regulate AMPAR receptor trafficking and neuronal plasticity [, ]. They also bind various receptor and signalling proteins, such as EphB receptors, ephrinB ligands, the proteoglycan NG2, the Fraser syndrome protein Fras1, and matrix metalloproteinase 5 [].This entry includes glutamate receptor-interacting protein 1/2 (GRIP1/2).
Genotype
Symbol: Frem1/Frem1
Background: C57BL/6J-Frem1
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Chen D
Year: 1999
Journal: Science
Title: Regulation of transcription by a protein methyltransferase.
Volume: 284
Issue: 5423
Pages: 2174-7
Publication
First Author: Brunkow ME
Year: 2001
Journal: Nat Genet
Title: Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
Volume: 27
Issue: 1
Pages: 68-73
Publication
First Author: Fouillade C
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.
Volume: 33
Issue: 1
Pages: 76-86
Publication
First Author: Kirilenko P
Year: 2008
Journal: Differentiation
Title: The efficiency of Xenopus primordial germ cell migration depends on the germplasm mRNA encoding the PDZ domain protein Grip2.
Volume: 76
Issue: 4
Pages: 392-403
Protein Domain
Type: Family
Description: This entry represent GRIP2. In mice GRIP2 functions downstream of Notch3/RBP-Jkappa to regulate myogenic tone in the brain arteries []. In Xenopus GRIP2 is involved in primordial germ cell development and migration []. Glutamate receptor-interacting proteins (GRIPs) are multi-PDZ domain scaffolding proteins required for dendrite development. There are two members of the GRIP family: GRIP1 and GRIP2/ABP (AMPA receptor binding protein) []. GRIPs regulate AMPAR receptor trafficking and neuronal plasticity [, ]. They also bind various receptor and signalling proteins, such as EphB receptors, ephrinB ligands, the proteoglycan NG2, the Fraser syndrome protein Fras1, and matrix metalloproteinase 5 [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Steinmetz CC
Year: 2016
Journal: Cell Rep
Title: Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.
Volume: 16
Issue: 10
Pages: 2711-2722
Publication
First Author: Means GD
Year: 2000
Journal: Genomics
Title: A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation.
Volume: 65
Issue: 3
Pages: 213-23
Protein
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 814  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
Publication
First Author: Audas TE
Year: 2008
Journal: Mol Cell Biol
Title: A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response.
Volume: 28
Issue: 12
Pages: 3952-66
Publication
First Author: Smyth I
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.
Volume: 101
Issue: 37
Pages: 13560-5
Publication
First Author: Chen YH
Year: 2005
Journal: Mol Cell Biol
Title: GAC63, a GRIP1-dependent nuclear receptor coactivator.
Volume: 25
Issue: 14
Pages: 5965-72
Publication
First Author: Hong H
Year: 1999
Journal: J Biol Chem
Title: Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3.
Volume: 274
Issue: 32
Pages: 22618-26
Publication
First Author: Yang CK
Year: 2006
Journal: J Biol Chem
Title: Differential use of functional domains by coiled-coil coactivator in its synergistic coactivator function with beta-catenin or GRIP1.
Volume: 281
Issue: 6
Pages: 3389-97
Publication
First Author: Huang SM
Year: 2000
Journal: Mol Cell Biol
Title: Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors.
Volume: 20
Issue: 5
Pages: 1855-67
Publication
First Author: Khanal T
Year: 2017
Journal: Sci Rep
Title: Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer.
Volume: 7
Issue: 1
Pages: 10662
Publication
First Author: Aoto J
Year: 2007
Journal: J Neurosci
Title: Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation.
Volume: 27
Issue: 28
Pages: 7508-19
Publication
First Author: Chinenov Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression.
Volume: 105
Issue: 51
Pages: 20185-90
Publication
First Author: Hoang T
Year: 2004
Journal: J Biol Chem
Title: cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1.
Volume: 279
Issue: 47
Pages: 49120-30
Publication
First Author: Reily MM
Year: 2006
Journal: EMBO J
Title: The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression.
Volume: 25
Issue: 1
Pages: 108-17
Publication
First Author: Flammer JR
Year: 2010
Journal: Mol Cell Biol
Title: The type I interferon signaling pathway is a target for glucocorticoid inhibition.
Volume: 30
Issue: 19
Pages: 4564-74
Publication
First Author: Puustinen R
Year: 2001
Journal: Eur J Endocrinol
Title: Localization of glucocorticoid receptor interacting protein 1 in murine tissues using two novel polyclonal antibodies.
Volume: 145
Issue: 3
Pages: 323-33
Publication
First Author: Park SW
Year: 2009
Journal: Nucleic Acids Res
Title: RIP140 in thyroid hormone-repression and chromatin remodeling of Crabp1 gene during adipocyte differentiation.
Volume: 37
Issue: 21
Pages: 7085-94
Publication
First Author: Druker J
Year: 2013
Journal: Mol Cell Biol
Title: RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activity.
Volume: 33
Issue: 11
Pages: 2116-27
Protein
Organism: Mus musculus/domesticus
Length: 139  
Fragment?: true
Publication
First Author: Vinh DB
Year: 2002
Journal: Mol Biol Cell
Title: Reconstitution and characterization of budding yeast gamma-tubulin complex.
Volume: 13
Issue: 4
Pages: 1144-57
Publication
First Author: Teixidó-Travesa N
Year: 2012
Journal: J Cell Sci
Title: The where, when and how of microtubule nucleation - one ring to rule them all.
Volume: 125
Issue: Pt 19
Pages: 4445-56
Publication
First Author: Hashimoto T
Year: 2013
Journal: Curr Opin Plant Biol
Title: A ring for all: γ-tubulin-containing nucleation complexes in acentrosomal plant microtubule arrays.
Volume: 16
Issue: 6
Pages: 698-703