Type |
Details |
Score |
Publication |
First Author: |
Glaser KM |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions. |
Volume: |
13 |
|
Pages: |
1039803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jaber M |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. |
Volume: |
93 |
Issue: |
23 |
Pages: |
12974-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rakesh K |
Year: |
2010 |
Journal: |
Sci Signal |
Title: |
beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress. |
Volume: |
3 |
Issue: |
125 |
Pages: |
ra46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teoh JP |
Year: |
2018 |
Journal: |
J Mol Cell Cardiol |
Title: |
β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling. |
Volume: |
118 |
|
Pages: |
225-236 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deltagen Inc |
Year: |
2005 |
Journal: |
MGI Direct Data Submission |
Title: |
NIH initiative supporting placement of Deltagen, Inc. mice into public repositories |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
348 |
Description: |
Phosphoserine; by GRK5 |
Type: |
modified residue |
End: |
348 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barthet G |
Year: |
2009 |
Journal: |
EMBO J |
Title: |
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. |
Volume: |
28 |
Issue: |
18 |
Pages: |
2706-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takagi C |
Year: |
1999 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Enhanced GRK5 expression in the hearts of cardiomyopathic hamsters, J2N-k. |
Volume: |
262 |
Issue: |
1 |
Pages: |
206-10 |
|
•
•
•
•
•
|
Allele |
Name: |
G protein-coupled receptor kinase 5; targeted mutation 2, Robert J Lefkowitz |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Liggett SB |
Year: |
2008 |
Journal: |
Nat Med |
Title: |
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. |
Volume: |
14 |
Issue: |
5 |
Pages: |
510-7 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
117 |
Description: |
Phosphoserine; by BARK1, CK2 and GRK5 |
Type: |
modified residue |
End: |
117 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1490 |
Description: |
Phosphoserine; by CDK14, GRK5 and GRK6 |
Type: |
modified residue |
End: |
1490 |
|
•
•
•
•
•
|
Allele |
Name: |
G protein-coupled receptor kinase 5; targeted mutation 1, Robert J Lefkowitz |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
G protein-coupled receptor kinase 5; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
590
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
G protein-coupled receptor kinase 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohba Y |
Year: |
2015 |
Journal: |
Biochem Biophys Res Commun |
Title: |
GRK6 phosphorylates IκBα at Ser(32)/Ser(36) and enhances TNF-α-induced inflammation. |
Volume: |
461 |
Issue: |
2 |
Pages: |
307-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rockman HA |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. |
Volume: |
93 |
Issue: |
18 |
Pages: |
9954-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagayama Y |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor. |
Volume: |
271 |
Issue: |
17 |
Pages: |
10143-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iaccarino G |
Year: |
1998 |
Journal: |
Am J Physiol |
Title: |
Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs. |
Volume: |
275 |
Issue: |
4 Pt 2 |
Pages: |
H1298-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Appleyard SM |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin. |
Volume: |
274 |
Issue: |
34 |
Pages: |
23802-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parameswaran N |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. |
Volume: |
281 |
Issue: |
45 |
Pages: |
34159-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu P |
Year: |
2010 |
Journal: |
Brain Res |
Title: |
G protein-coupled receptor kinase 5, overexpressed in the alpha-synuclein up-regulation model of Parkinson's disease, regulates bcl-2 expression. |
Volume: |
1307 |
|
Pages: |
134-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maimari T |
Year: |
2019 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors. |
Volume: |
520 |
Issue: |
2 |
Pages: |
327-332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toya M |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
10481 |
|
•
•
•
•
•
|