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Search results 301 to 379 out of 379 for Gsdmd

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Type Details Score
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE241549 | GSDMD knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
34010648 | J:317355
First Author: Ratitong B
Year: 2021
Journal: Cell Rep
Title: β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles.
Volume: 35
Issue: 7
Pages: 109139
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Publication
37593179 | J:347972
 
First Author: Zhang BL
Year: 2023
Journal: Front Pharmacol
Title: Inhibition of GSDMD activation by Z-LLSD-FMK or Z-YVAD-FMK reduces vascular inflammation and atherosclerotic lesion development in ApoE(-/-) mice.
Volume: 14
Pages: 1184588
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Allele
Gsdmd<em2Smoc> | MGI:7290030
Name: gasdermin D; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475437 | C57BL/6JSmoc-Gsdmd<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
27418190 | -
First Author: Sborgi L
Year: 2016
Journal: EMBO J
Title: GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
Volume: 35
Issue: 16
Pages: 1766-78
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Allele
Gsdmd<em1Smoc> | MGI:7290029
Name: gasdermin D; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6354810 | C57BL/6JSmoc-Gsdmd<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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HT Experiment
GSE247326 | Gasdermin D deficiency affects mitochondrial dynamics and metabolic to orchestrates neurogenesis during embryonic development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Gsdmd<m1Btlr> | MGI:6268770
Name: gasdermin D; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6268771 | C57BL/6J-Gsdmd<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Gsdmd/Gsdmd
Background: C57BL/6J-Gsdmd
Zygosity: hm
Has Mutant Allele: true
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Publication
30381458 | J:267270
First Author: Sarhan J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
Volume: 115
Issue: 46
Pages: E10888-E10897
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Publication
36652908 | J:347650
First Author: Muñoz-Wolf N
Year: 2023
Journal: Cell Rep Med
Title: Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles.
Volume: 4
Issue: 1
Pages: 100899
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Publication
33205073 | J:348114
First Author: Ma H
Year: 2020
Journal: Cell Rep Med
Title: Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction.
Volume: 1
Issue: 6
Pages: 100097
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Publication
38965211 | J:360392
First Author: Yow SJ
Year: 2024
Journal: Cell Death Dis
Title: Differential signalling requirements for RIPK1-dependent pyroptosis in neutrophils and macrophages.
Volume: 15
Issue: 7
Pages: 479
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Publication
35508125 | J:344029
First Author: Vasudevan SO
Year: 2022
Journal: Cell Rep
Title: A TLR4-independent critical role for CD14 in intracellular LPS sensing.
Volume: 39
Issue: 5
Pages: 110755
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Publication
38522070 | J:349723
First Author: Wright SS
Year: 2024
Journal: Cell Rep
Title: A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis.
Volume: 43
Issue: 4
Pages: 114004
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Publication
30135078 | J:265832
First Author: Lee BL
Year: 2018
Journal: J Exp Med
Title: Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation.
Volume: 215
Issue: 9
Pages: 2279-2288
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Publication
32367036 | J:306397
First Author: Hu JJ
Year: 2020
Journal: Nat Immunol
Title: FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Volume: 21
Issue: 7
Pages: 736-745
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Publication
34858995 | J:315152
 
First Author: Wu J
Year: 2021
Journal: Front Cell Dev Biol
Title: Treatment of Severe Acute Pancreatitis and Related Lung Injury by Targeting Gasdermin D-Mediated Pyroptosis.
Volume: 9
Pages: 780142
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Publication
35849616 | J:327170
First Author: Santoni K
Year: 2022
Journal: PLoS Pathog
Title: Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa.
Volume: 18
Issue: 7
Pages: e1010305
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Publication
36109515 | J:330852
First Author: Tonnus W
Year: 2022
Journal: Cell Death Dis
Title: Gasdermin D-deficient mice are hypersensitive to acute kidney injury.
Volume: 13
Issue: 9
Pages: 792
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Publication
28459430 | J:250434
First Author: Wang Y
Year: 2017
Journal: Nature
Title: Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Volume: 547
Issue: 7661
Pages: 99-103
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Publication
27281216 | J:296107
First Author: Ding J
Year: 2016
Journal: Nature
Title: Pore-forming activity and structural autoinhibition of the gasdermin family.
Volume: 535
Issue: 7610
Pages: 111-6
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Publication
37316538 | J:336750
First Author: Ito M
Year: 2023
Journal: Sci Rep
Title: ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease.
Volume: 13
Issue: 1
Pages: 9616
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Publication
29352265 | J:305141
First Author: Li Y
Year: 2018
Journal: Cell Death Differ
Title: Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection.
Volume: 25
Issue: 7
Pages: 1304-1318
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Publication
27573815 | J:237229
First Author: Jorgensen I
Year: 2016
Journal: J Exp Med
Title: Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis.
Volume: 213
Issue: 10
Pages: 2113-28
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Publication
30250284 | J:294459
First Author: Zhang Z
Year: 2018
Journal: Cell Death Dis
Title: Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury.
Volume: 9
Issue: 10
Pages: 983
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Publication
34644617 | J:336483
 
First Author: Dhar R
Year: 2021
Journal: Free Radic Biol Med
Title: Phosphodiesterase 4B is required for NLRP3 inflammasome activation by positive feedback with Nrf2 in the early phase of LPS- induced acute lung injury.
Volume: 176
Pages: 378-391
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Publication
32454054 | J:291382
 
First Author: Li DX
Year: 2020
Journal: Behav Brain Res
Title: NLRP3 inflammasome-dependent pyroptosis and apoptosis in hippocampus neurons mediates depressive-like behavior in diabetic mice.
Volume: 391
Pages: 112684
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Publication
36626177 | J:344499
First Author: Cao X
Year: 2023
Journal: Invest Ophthalmol Vis Sci
Title: Aquaporin5 Deficiency Aggravates ROS/NLRP3 Inflammasome-Mediated Pyroptosis in the Lacrimal Glands.
Volume: 64
Issue: 1
Pages: 4
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Publication
37980412 | J:352389
First Author: Dondelinger Y
Year: 2023
Journal: Cell Death Dis
Title: NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis.
Volume: 14
Issue: 11
Pages: 755
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Publication
29510138 | J:270940
First Author: Pan J
Year: 2018
Journal: Biochem Biophys Res Commun
Title: AIM2 accelerates the atherosclerotic plaque progressions in ApoE-/- mice.
Volume: 498
Issue: 3
Pages: 487-494
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Publication
29666477 | J:274638
First Author: de Vasconcelos NM
Year: 2019
Journal: Cell Death Differ
Title: Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture.
Volume: 26
Issue: 1
Pages: 146-161
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Publication
31189875 | J:285694
First Author: Xue Z
Year: 2019
Journal: Cell Death Dis
Title: miR-21 promotes NLRP3 inflammasome activation to mediate pyroptosis and endotoxic shock.
Volume: 10
Issue: 6
Pages: 461
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Publication
30897338 | J:296002
First Author: Dapaah-Siakwan F
Year: 2019
Journal: Am J Respir Cell Mol Biol
Title: Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice.
Volume: 61
Issue: 3
Pages: 341-354
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Publication
32431709 | J:308201
 
First Author: Sanches RCO
Year: 2020
Journal: Front Immunol
Title: NLRP6 Plays an Important Role in Early Hepatic Immunopathology Caused by Schistosoma mansoni Infection.
Volume: 11
Pages: 795
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Publication
33361087 | J:327023
First Author: Kiss M
Year: 2021
Journal: Cancer Immunol Res
Title: IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D.
Volume: 9
Issue: 3
Pages: 309-323
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Publication
34984912 | J:331549
First Author: Wu Y
Year: 2022
Journal: Hypertension
Title: Caspase-4/11-Mediated Pulmonary Artery Endothelial Cell Pyroptosis Contributes to Pulmonary Arterial Hypertension.
Volume: 79
Issue: 3
Pages: 536-548
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Publication
35637281 | J:327302
First Author: Yao Q
Year: 2022
Journal: Cell Mol Immunol
Title: Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3.
Volume: 19
Issue: 8
Pages: 883-897
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Publication
37979447 | J:343487
 
First Author: Liu C
Year: 2023
Journal: Redox Biol
Title: CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway.
Volume: 68
Pages: 102960
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Publication
38092000 | J:351166
First Author: Zheng S
Year: 2023
Journal: Mol Cell
Title: ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation.
Volume: 83
Issue: 24
Pages: 4570-4585.e7
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Publication
39644526 | J:360802
 
First Author: Qu X
Year: 2025
Journal: Redox Biol
Title: Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury.
Volume: 79
Pages: 103455
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Publication
37955123 | J:345572
First Author: Sawai Y
Year: 2024
Journal: Am J Physiol Cell Physiol
Title: Caveolin-1 forms a complex with P2X7 receptor and tunes P2X7-mediated ATP signaling in mouse bone marrow-derived macrophages.
Volume: 326
Issue: 1
Pages: C125-C142
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Publication
35187871 | J:339547
First Author: He D
Year: 2022
Journal: J Periodontal Implant Sci
Title: Dec2 inhibits macrophage pyroptosis to promote periodontal homeostasis.
Volume: 52
Issue: 1
Pages: 28-38
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Publication
30589883 | J:333171
First Author: Cerqueira DM
Year: 2018
Journal: PLoS Pathog
Title: Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.
Volume: 14
Issue: 12
Pages: e1007519
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Publication
34979900 | J:335415
First Author: Zhou J
Year: 2022
Journal: Mol Med
Title: Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.
Volume: 28
Issue: 1
Pages: 1
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Publication
36776889 | J:343348
 
First Author: Drummer C 4th
Year: 2023
Journal: Front Immunol
Title: Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.
Volume: 14
Pages: 1113883
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Publication
37921870 | J:348459
First Author: Hong W
Year: 2023
Journal: Aging (Albany NY)
Title: Effects of amyloid β (Aβ)42 and Gasdermin D on the progression of Alzheimer's disease in vitro and in vivo through the regulation of astrocyte pyroptosis.
Volume: 15
Issue: 21
Pages: 12209-12224
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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