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Search results 301 to 400 out of 1398 for H2ax

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-30
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6727336
Age: postnatal day 25
Image: 3O
Note: Expression only in XY bodies.
Specimen Label: 3O
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-30
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6727336
Age: postnatal day 25
Image: 3P
Note: Expression in chromatin domains surrounding double strand breaks (DSB).
Specimen Label: 3P
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-30
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6727336
Age: postnatal day 25
Image: 3Q
Note: Expression in chromatin domains surrounding double strand breaks (DSB).
Specimen Label: 3Q
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-30
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6727336
Age: postnatal day 25
Image: 3R
Note: Expression persisted on chromatin of unsynapsed axes.
Specimen Label: 3R
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6730366
Age: postnatal adult
Image: 1B
Note: Expression in pachytene cells, accumulated in XY body, and leptotene cells, diffusely expressed in nuclei.
Specimen Label: 1B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6730366
Age: postnatal adult
Image: 1C
Note: Expression in pachytene cells, accumulated in XY body, and leptotene cells, diffusely expressed in nuclei.
Specimen Label: 1C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464301
Age: postnatal month 7
Image: 1Da
Note: Expression in stage IX tubules with leptotene spermatocytes.
Specimen Label: 1Da
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464301
Age: postnatal month 7
Image: 1Db
Note: Expression in stage IX tubules with leptotene spermatocytes.
Specimen Label: 1Db
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 12
Image: 7Ba
Note: Expression in wave of leptotene/zygotene spermatocytes.
Specimen Label: 7Ba
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 12
Image: 7Bb
Note: Expression in wave of leptotene/zygotene spermatocytes.
Specimen Label: 7Bb
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Weak
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 12
Image: 7Bc
Note: Reduced numbers of expressing cells compared to control.
Specimen Label: 7Bc
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 12
Image: 7Bd
Note: Expression in XY body in pachytene spermatocyte.
Specimen Label: 7Bd
Detected: true
Specimen Num: 4
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•
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•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 18
Image: 7Bg
Note: Authors report synchronous onset of spermatogenesis. Diminished density of leptotene spermatocytes.
Specimen Label: 7Bg
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 18
Image: 7Bi
Note: Expression in XY body in pachytene spermatocytes.
Specimen Label: 7Bi
Detected: true
Specimen Num: 9
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7464303
Age: postnatal day 18
Image: 7Bj
Note: Expression in XY body in pachytene spermatocytes.
Specimen Label: 7Bj
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5A gH2AX leptotene
Note: Expression on autosomal chromatin, distributed widely throughout nucleus.
Specimen Label: 5A gH2AX leptotene
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5A gH2AX zygotene
Note: Expression on autosomal chromatin, distributed widely throughout nucleus.
Specimen Label: 5A gH2AX zygotene
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5A gH2AX pachytene
Note: Expression restricted to XY chromatin.
Specimen Label: 5A gH2AX pachytene
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5A gH2AX diplotene
Note: Expression restricted to XY chromatin.
Specimen Label: 5A gH2AX diplotene
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Strong
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5B gH2AX leptotene
Note: Strong expression in leptotene and zygotene spermatocytes.
Specimen Label: 5B gH2AX leptotene
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Strong
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5B gH2AX zygotene-like
Note: Strong expression in leptotene and zygotene spermatocytes.
Specimen Label: 5B gH2AX zygotene-like
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7509248
Age: postnatal day 25
Image: 5B gH2AX pachytene-like
Note: Express throughout nucleus.
Specimen Label: 5B gH2AX pachytene-like
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7610603
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610717
Age: postnatal adult
Note: Expressed in the the XY body.
Specimen Label: 3A Spermatocytes Pachytene
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7610603
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610718
Age: postnatal adult
Note: Expressed in the the XY body.
Specimen Label: 4A Early-pachy
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7610603
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610718
Age: postnatal adult
Note: Expressed in the the XY body.
Specimen Label: 4A Mid-pachy
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7610603
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7610718
Age: postnatal adult
Note: Expressed in the the XY body.
Specimen Label: 4A Late-pachy
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7610603
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610718
Age: postnatal adult
Note: Expressed in the the XY body.
Specimen Label: 4B Late-diplo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6720909
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7663010
Age: postnatal adult
Image: 1Ca,b,c
Note: Pronounced expression at pachytene stage.
Specimen Label: 1Ca,b,c
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5911991
Assay Type: Immunohistochemistry
Annotation Date: 2017-11-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:5912260
Age: embryonic day 3.5
Image: 3B WT
Specimen Label: 3B WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5911991
Assay Type: Immunohistochemistry
Annotation Date: 2017-11-01
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:5912260
Age: embryonic day 3.5
Image: 3B KO
Specimen Label: 3B KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3584853
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:3585394
Age: postnatal day 4-5
Image: P4/5
Specimen Label: P4/5
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3584853
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:3585394
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3584853
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:3585394
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3584853
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Male
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:3585394
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:6383727
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6383808
Age: embryonic day 13.5
Image: 2b
Note: Immunostaining showed a classical focal distribution.
Specimen Label: 2b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6383727
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6383808
Age: embryonic day 13.5
Image: 2c
Note: Immunostaining showed a classical focal distribution. The number of cells with foci, as well as the number of foci per cell, was higher in the mutant compared to wild type.
Specimen Label: 2c
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1716820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6506440
Age: embryonic day 12.5
Specimen Label: 4F E12.5 Atrip
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6506440
Age: postnatal day 2
Specimen Label: 4F P2 Atrip
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6506440
Age: postnatal day 4
Specimen Label: 4F P4 Atrip
Detected: true
Specimen Num: 7
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1716825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6506440
Age: embryonic day 17.5
Image: 4E Atrip
Specimen Label: 4E Atrip
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6506440
Age: embryonic day 17.5
Image: 4E Atrip
Note: A substantial increase in DNA damage was detected in the mutant retina.
Specimen Label: 4E Atrip
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1716820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6506440
Age: embryonic day 12.5
Note: No change in DNA damage was detected in the mutant retina.
Specimen Label: 4F E12.5 Atrip
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6506440
Age: postnatal day 2
Note: A modest increase in DNA damage was detected in the mutant retina.
Specimen Label: 4F P2 Atrip
Detected: true
Specimen Num: 6
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6506440
Age: postnatal day 4
Specimen Label: 4F P4 Atrip
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1716825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6506440
Age: embryonic day 17.5
Image: S3C Atrip
Specimen Label: S3C Atrip
Specimen Num: 9
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6506440
Age: embryonic day 17.5
Image: S3C Atrip
Note: DNA damage was in the retinal periphery.
Specimen Label: S3C Atrip
Detected: true
Specimen Num: 10
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:3600023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7466386
Age: embryonic day 15.5
Note: Unlike in wild type XY gonads, cells are in an advanced stage of meiosis.
Specimen Label: 1D XY Cyp26b1 KO - upper
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-25
Strength: Present
Sex: Male
Emaps: EMAPS:3600023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7466386
Age: embryonic day 15.5
Note: Unlike in wild type XY gonads, cells are in an advanced stage of meiosis.
Specimen Label: S4B - left
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7782551
Assay Type: Immunohistochemistry
Annotation Date: 2024-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3600024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7783743
Age: embryonic day 16.5
Image: 10E XY FOG2cKO left
Note: The majority of the germ cells in the mutant expressed this meiosis-associated marker.
Specimen Label: 10E XY FOG2cKO left
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:7782551
Assay Type: Immunohistochemistry
Annotation Date: 2024-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3600024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7783743
Age: embryonic day 16.5
Image: 10E XY FOG2cKO right
Note: The majority of the germ cells in the mutant expressed this meiosis-associated marker.
Specimen Label: 10E XY FOG2cKO right
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5689407
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3563228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620155
Age: postnatal week 6
Image: 2J Rtcb oo-/- (upper)
Note: Obvious DNA damage in more than 50% of oocytes in secondary and antral follicles.
Specimen Label: 2J Rtcb oo-/- (upper)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7545046
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7545052
Age: embryonic day 18.5
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7545046
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7545052
Age: embryonic day 18.5
Image: 3D
Note: Increased expression compared with the wild-type.
Specimen Label: 3D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7711947
Age: embryonic day 11.5
Image: 3K Ctrl LV
Specimen Label: 3K Ctrl LV
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6430453
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7711947
Age: embryonic day 11.5
Image: 3K cKO LV
Note: Significantly increased level of DNA damage (H2ax+) compared with the control.
Specimen Label: 3K cKO LV
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5689407
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-10
Strength: Present
Sex: Male
Emaps: EMAPS:2910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7628675
Age: embryonic day 16.5
Image: 3A Control
Note: Prominent expression in 10% of Sertoli cells with Gata4 foci: 4.1% localized and 6.2% widespread.
Specimen Label: 3A Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5689407
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-10
Strength: Present
Sex: Male
Emaps: EMAPS:2910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7628675
Age: embryonic day 16.5
Image: 3B ScAttrxKO
Note: Widespread expresssion in Sertoli cells with regular-sized Gata4 foci (5.8%); localized expression in 43.7%. Expresssion in all G2/M arrested Sertoli cells with giant Gata4 foci (51% localized and 48.3% localized).
Specimen Label: 3B ScAttrxKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5689407
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-09
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:160657
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7516307
Age: embryonic day 5.25
Image: 1E gammH2AX Pr-set7f/f
Note: Expression in control not described
Specimen Label: 1E gammH2AX Pr-set7f/f
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5689407
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:160657
Pattern: Widespread
Stage: TS07
Assay Id: MGI:7516307
Age: embryonic day 5.25
Image: 1E gammH2AX Pr-set7fd/d
Note: Authors report massive DNA damage in trophoblasts in extraembryonic ectoderm.
Specimen Label: 1E gammH2AX Pr-set7fd/d
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: 4B Paxx+/+;Xlf+/+
Specimen Label: 4B Paxx+/+;Xlf+/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: 4B Paxx+/+;Xlf-/-
Specimen Label: 4B Paxx+/+;Xlf-/-
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: 4B Paxx-/-;Xlf+/+
Specimen Label: 4B Paxx-/-;Xlf+/+
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: 4B Paxx-/-;Xlf-/-
Specimen Label: 4B Paxx-/-;Xlf-/-
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7448592
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-30
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7448694
Age: embryonic day 12.5
Image: 2A CNS-ctr
Note: Expression in control was not described.
Specimen Label: 2A CNS-ctr
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:7548343
Age: embryonic day 14.5
Image: 1D WT
Specimen Label: 1D WT
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548343
Age: embryonic day 14.5
Image: 1D BubR1 cKO
Note: Significant increase in expression compared to wild type.
Specimen Label: 1D BubR1 cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3G gH2AX WT
Note: Authors report a lack of significant DNA damage in wild type and Trp53 cKO groups.
Specimen Label: 3G gH2AX WT
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3G gH2AX Trp53 cKO
Note: Authors report a lack of significant DNA damage in wild type and Trp53 cKO groups.
Specimen Label: 3G gH2AX Trp53 cKO
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3G gH2AX BubR1 cKO
Note: Number of expressing cells signficantly increased compared to wild type.
Specimen Label: 3G gH2AX BubR1 cKO
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3G gH2AX dcKO
Note: Number of expressing cells not altered compared to BubR1 cKO.
Specimen Label: 3G gH2AX dcKO
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3J gH2AX WT
Note: Authors report a lack of significant DNA damage in wild type and Trp53 cKO groups.
Specimen Label: 3J gH2AX WT
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3J gH2AX Trp53 cKO
Note: Authors report a lack of significant DNA damage in wild type and Trp53 cKO groups.
Specimen Label: 3J gH2AX Trp53 cKO
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3J gH2AX BubR1 cKO
Note: Significant number of expressing cells are undergoing apoptosis.
Specimen Label: 3J gH2AX BubR1 cKO
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7464275
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548372
Age: embryonic day 14.5
Image: 3J gH2AX dcKO
Note: Number of expressing cells not altered compared to BubR1 cKO.
Specimen Label: 3J gH2AX dcKO
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 1A Ctrl
Note: Only a few foci (DNA damage) were seen.
Specimen Label: 1A Ctrl
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Strong
Sex: Male
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 1A cKO
Note: A high level of DNA damage throughout the cortex was seen.
Specimen Label: 1A cKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Strong
Sex: Male
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 1A cKO;p53-/-
Note: A high level of DNA damage throughout the cortex was seen, higher than the single cKO.
Specimen Label: 1A cKO;p53-/-
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7705273
Age: postnatal day 0.5
Image: 1B Ctrl
Note: Only a few foci were seen.
Specimen Label: 1B Ctrl
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7705273
Age: postnatal day 0.5
Image: 1B cKO
Note: The level of DNA damage was appreciably lower in the neonatal brain. A higher level of DNA damage throughout the cortex was seen.
Specimen Label: 1B cKO
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7705273
Age: postnatal day 0.5
Image: 1B cKO;p53-/-
Note: The level of DNA damage was appreciably lower in the neonatal brain. A higher level of DNA damage throughout the cortex was seen.
Specimen Label: 1B cKO;p53-/-
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Note: Similar as in the control.
Specimen Label: not shown p53-/-
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Absent
Sex: Male
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7705273
Age: postnatal day 7
Image: S1A Ctrl
Specimen Label: S1A Ctrl
Detected: false
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Absent
Sex: Male
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7705273
Age: postnatal day 7
Image: S1A cKO
Specimen Label: S1A cKO
Detected: false
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7705273
Age: postnatal day 0.5
Note: Similar as in the control.
Specimen Label: not shown p53-/-
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 3C cKO
Note: More DNA damage (H2ax+) at the late replication foci (Pcna+) compared with control cells, confirming an increase in double-stranded breaks during the replication process.
Specimen Label: 3C cKO
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 3C Ctrl
Note: Only a few foci (DNA damage) were seen.
Specimen Label: 3C Ctrl
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: S8B lung WT
Specimen Label: S8B lung WT
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: S8B lung Paxx-/-
Note: Expression was the same as in wild-type.
Specimen Label: S8B lung Paxx-/-
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: S8B lung Xlf-/-
Note: Expression was the same as in wild-type.
Specimen Label: S8B lung Xlf-/-
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5305847
Assay Type: Immunohistochemistry
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5827984
Age: embryonic day 14.5
Image: S8B lung Paxx-/-;Xlf-/-
Note: Expression was the same as in wild-type.
Specimen Label: S8B lung Paxx-/-;Xlf-/-
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7384637
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7384790
Age: embryonic day 16.5
Specimen Label: S6A +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7384637
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7384790
Age: embryonic day 16.5
Note: In this mutant there is an increase in positive cells compared with wild type controls.
Specimen Label: S6A Fancd2<-/->
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7384637
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7384790
Age: embryonic day 16.5
Note: Expression in this mutant is similar to wild-type.
Specimen Label: S6A Foxo3a<-/->
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7384637
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7384790
Age: embryonic day 16.5
Note: In this mutant a large fraction of the brain had positive cells compared to wild-type.
Specimen Label: S6A DKO
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Note: Only a few foci were seen in hippocampal hem (future hippocampus) and basal ganglia.
Specimen Label: not shown Ctrl
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Strong
Sex: Male
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Note: A high level of DNA damage throughout the hippocampal hem (future hippocampus) and basal ganglia was seen.
Specimen Label: not shown cKO
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Strong
Sex: Male
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Note: A high level of DNA damage throughout the hippocampal hem (future hippocampus) and basal ganglia was seen. Expression in the hippocampal hem was higher than the single cKO.
Specimen Label: not shown cKO;p53-/-
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Note: Expression in the hippocampal hem (future hippocampus) and basal ganglia was similar as in the control.
Specimen Label: not shown p53-/-
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 1C Ctrl
Note: Only a few foci were seen, and the majority was not positive for cleaved caspase-3.
Specimen Label: 1C Ctrl
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7705232
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7705273
Age: embryonic day 13.5
Image: 1C cKO
Note: The majority of cells undergoing apoptosis (i.e., cleaved caspase-3+ cells) in the cKO telencephalon also stained positive for H2ax.
Specimen Label: 1C cKO
Detected: true
Specimen Num: 16
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