| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jenkins ZA |
| Year: |
1999 |
| Journal: |
Anim Genet |
| Title: |
Genetic mapping of the ovine homologue of the mouse Hacl1 gene to sheep chromosome 1. |
| Volume: |
30 |
| Issue: |
1 |
| Pages: |
74 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Foulon V |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids. |
| Volume: |
96 |
| Issue: |
18 |
| Pages: |
10039-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kitamura T |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum. |
| Volume: |
114 |
| Issue: |
13 |
| Pages: |
E2616-E2623 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fraccascia P |
| Year: |
2011 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Role of thiamine pyrophosphate in oligomerisation, functioning and import of peroxisomal 2-hydroxyacyl-CoA lyase. |
| Volume: |
1814 |
| Issue: |
10 |
| Pages: |
1226-33 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents a group of TPP-binding domain containing proteins, including oxalyl-CoA decarboxylase from E. coli, IorA from Thermococcus kodakarensis and HACL1 from animals. In general, they are thiamine pyrophosphate-dependent enzymes that catalyse the carbon-carbon bond cleavage []. In humans, HACL1 is a peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxidation in a thiamine pyrophosphate (TPP)-dependent manner [, , ]. It is also involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids [, , ]. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
109
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
105
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
74
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
122
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mori K |
| Year: |
2023 |
| Journal: |
Mol Biol Cell |
| Title: |
Role of 2-hydroxy acyl-CoA lyase HACL2 in odd-chain fatty acid production via α-oxidation in vivo. |
| Volume: |
34 |
| Issue: |
9 |
| Pages: |
ar85 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
581
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
554
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
521
 |
| Fragment?: |
false |
|
•
•
•
•
•
|