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Search results 301 to 400 out of 2041 for Ins2

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Type Details Score
Publication
18443355 | J:150239
First Author: Lorenzen J
Year: 2008
Journal: J Am Soc Nephrol
Title: The role of osteopontin in the development of albuminuria.
Volume: 19
Issue: 5
Pages: 884-90
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37103008 | J:335551
First Author: Dallacasagrande V
Year: 2023
Journal: Invest Ophthalmol Vis Sci
Title: Blockade of Annexin A2 Prevents Early Microvasculopathy in Murine Models of Diabetic Retinopathy.
Volume: 64
Issue: 4
Pages: 33
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Publication
31091127 | J:281029
First Author: Song P
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Knockout of Na+-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration.
Volume: 317
Issue: 1
Pages: F207-F217
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Publication
26586006 | J:319192
First Author: Kadoya H
Year: 2016
Journal: Clin Exp Nephrol
Title: Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.
Volume: 20
Issue: 5
Pages: 671-678
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Publication
22297672 | J:198186
First Author: Yu L
Year: 2012
Journal: Kidney Int
Title: Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.
Volume: 81
Issue: 11
Pages: 1086-97
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Publication
27206247 | J:254653
First Author: Wang J
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2Akita/+ Murine Model of Diabetic Retinopathy.
Volume: 57
Issue: 6
Pages: 2770-81
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Publication
29761600 | J:268801
First Author: Duan Y
Year: 2018
Journal: Stem Cells
Title: Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction.
Volume: 36
Issue: 9
Pages: 1430-1440
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Publication
30425286 | J:268145
First Author: Saddala MS
Year: 2018
Journal: Sci Rep
Title: Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina.
Volume: 8
Issue: 1
Pages: 16728
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Publication
36672207 | J:336232
 
First Author: Hagmann H
Year: 2023
Journal: Cells
Title: Capsazepine (CPZ) Inhibits TRPC6 Conductance and Is Protective in Adriamycin-Induced Nephropathy and Diabetic Glomerulopathy.
Volume: 12
Issue: 2
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Publication
32684737 | J:310413
First Author: Herat LY
Year: 2020
Journal: World J Gastroenterol
Title: Sodium glucose co-transporter 2 inhibition reduces succinate levels in diabetic mice.
Volume: 26
Issue: 23
Pages: 3225-3235
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Publication
27475229 | J:325384
First Author: Takashima S
Year: 2016
Journal: Kidney Int
Title: Stromal cell-derived factor-1 is upregulated by dipeptidyl peptidase-4 inhibition and has protective roles in progressive diabetic nephropathy.
Volume: 90
Issue: 4
Pages: 783-96
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Publication
33831261 | J:325387
First Author: Leanza G
Year: 2021
Journal: J Bone Miner Res
Title: Gain-of-Function Lrp5 Mutation Improves Bone Mass and Strength and Delays Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes.
Volume: 36
Issue: 7
Pages: 1403-1415
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Publication
32590005 | J:325391
 
First Author: Sergeys J
Year: 2020
Journal: Exp Eye Res
Title: The retinal tyrosine kinome of diabetic Akimba mice highlights potential for specific Src family kinase inhibition in retinal vascular disease.
Volume: 197
Pages: 108108
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Publication
23077100 | J:191244
First Author: Grutzmacher C
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Aberrant production of extracellular matrix proteins and dysfunction in kidney endothelial cells with a short duration of diabetes.
Volume: 304
Issue: 1
Pages: F19-30
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Publication
21810600 | J:347750
First Author: Naito M
Year: 2011
Journal: Diabetes
Title: Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice.
Volume: 60
Issue: 9
Pages: 2265-73
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15731364 | J:99270
First Author: Lu YC
Year: 2005
Journal: Endocrinology
Title: Release of transgenic human insulin from gastric g cells: a novel approach for the amelioration of diabetes.
Volume: 146
Issue: 6
Pages: 2610-9
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21880831 | J:180042
First Author: Awad AS
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Monocyte/macrophage chemokine receptor CCR2 mediates diabetic renal injury.
Volume: 301
Issue: 6
Pages: F1358-66
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32734440 | J:294918
First Author: Van Hove I
Year: 2020
Journal: Diabetologia
Title: Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy.
Volume: 63
Issue: 10
Pages: 2235-2248
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22474255 | J:212515
First Author: Patel VB
Year: 2012
Journal: Circ Res
Title: Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis.
Volume: 110
Issue: 10
Pages: 1322-35
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Publication
29074590 | J:269248
First Author: Paquin-Veillette J
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Deletion of AT2 Receptor Prevents SHP-1-Induced VEGF Inhibition and Improves Blood Flow Reperfusion in Diabetic Ischemic Hindlimb.
Volume: 37
Issue: 12
Pages: 2291-2300
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Publication
27820699 | J:237822
First Author: Lee J
Year: 2016
Journal: J Clin Invest
Title: Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.
Volume: 126
Issue: 12
Pages: 4616-4625
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30646747 | J:281960
First Author: Wu S
Year: 2019
Journal: Circulation
Title: Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes In Vivo.
Volume: 139
Issue: 16
Pages: 1913-1936
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27482904 | J:251509
First Author: Binz N
Year: 2016
Journal: PLoS One
Title: Biomarkers for Diabetic Retinopathy - Could Endothelin 2 Be Part of the Answer?
Volume: 11
Issue: 8
Pages: e0160442
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24966386 | J:212541
First Author: Rudchenko A
Year: 2014
Journal: J Neurosci
Title: Synapses on sympathetic neurons and parasympathetic neurons differ in their vulnerability to diabetes.
Volume: 34
Issue: 26
Pages: 8865-74
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29434227 | J:262677
First Author: Chaurasia SS
Year: 2018
Journal: Sci Rep
Title: The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy.
Volume: 8
Issue: 1
Pages: 2847
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Publication
21555558 | J:171899
First Author: Fox R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
Volume: 108
Issue: 21
Pages: 8779-84
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Publication
23416061 | J:202436
First Author: Yamaguchi K
Year: 2013
Journal: Biochim Biophys Acta
Title: Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion.
Volume: 1830
Issue: 6
Pages: 3656-63
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18439911 | J:136249
First Author: Hirosawa M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Ablation of estrogen receptor alpha (ERalpha) prevents upregulation of POMC by leptin and insulin.
Volume: 371
Issue: 2
Pages: 320-3
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Publication
24703908 | J:229882
 
First Author: Wisniewska-Kruk J
Year: 2014
Journal: Exp Eye Res
Title: Molecular analysis of blood-retinal barrier loss in the Akimba mouse, a model of advanced diabetic retinopathy.
Volume: 122
Pages: 123-31
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22386934 | J:319483
First Author: Usui M
Year: 2012
Journal: Metabolism
Title: Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance.
Volume: 61
Issue: 8
Pages: 1118-28
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Publication
31492508 | J:297189
First Author: Zhang D
Year: 2019
Journal: Kidney Int
Title: The caveolin-1 regulated protein follistatin protects against diabetic kidney disease.
Volume: 96
Issue: 5
Pages: 1134-1149
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Publication
29913163 | J:271962
 
First Author: Jiang H
Year: 2018
Journal: Exp Eye Res
Title: Loss-of-function mutation of serine racemase attenuates retinal ganglion cell loss in diabetic mice.
Volume: 175
Pages: 90-97
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Publication
22883233 | J:187377
First Author: Lerner AG
Year: 2012
Journal: Cell Metab
Title: IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Volume: 16
Issue: 2
Pages: 250-64
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Publication
17600118 | J:123932
First Author: Wong DW
Year: 2007
Journal: Am J Pathol
Title: Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury.
Volume: 171
Issue: 2
Pages: 438-51
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Publication
30488085 | J:276214
First Author: Yoshitake S
Year: 2019
Journal: Diabetologia
Title: Anti-fumarase antibody promotes the dropout of photoreceptor inner and outer segments in diabetic macular oedema.
Volume: 62
Issue: 3
Pages: 504-516
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Publication
33090974 | J:331044
 
First Author: Cai Z
Year: 2021
Journal: J Clin Invest
Title: Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine-induced lncRNA Morrbid.
Volume: 131
Issue: 1
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Publication
22297234 | J:181355
First Author: Grupillo M
Year: 2012
Journal: Cell Immunol
Title: Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells.
Volume: 273
Issue: 2
Pages: 115-23
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Publication
30899071 | J:276666
First Author: Foo KS
Year: 2019
Journal: Sci Rep
Title: Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity.
Volume: 9
Issue: 1
Pages: 4965
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16612590 | J:111475
First Author: Babaya N
Year: 2006
Journal: Diabetologia
Title: A new model of insulin-deficient diabetes: male NOD mice with a single copy of Ins1 and no Ins2.
Volume: 49
Issue: 6
Pages: 1222-8
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26155745 | J:226440
First Author: Templeman NM
Year: 2015
Journal: Diabetologia
Title: Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity.
Volume: 58
Issue: 10
Pages: 2392-402
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11897712 | J:106827
First Author: Duvillié B
Year: 2002
Journal: Endocrinology
Title: Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin.
Volume: 143
Issue: 4
Pages: 1530-7
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25233132 | J:218054
 
First Author: Blum B
Year: 2014
Journal: Elife
Title: Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
Volume: 3
Pages: e02809
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Publication
35044447 | J:340541
First Author: Liang W
Year: 2022
Journal: Diabetes
Title: Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling.
Volume: 71
Issue: 4
Pages: 747-761
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Publication
33667344 | J:303708
First Author: McKimpson WM
Year: 2021
Journal: Dev Cell
Title: Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes.
Volume: 56
Issue: 6
Pages: 747-760.e6
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Publication
31624141 | J:287848
First Author: Tan SM
Year: 2020
Journal: Diabetes
Title: Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility.
Volume: 69
Issue: 1
Pages: 83-98
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Publication
29654303 | J:263120
First Author: Zhao XP
Year: 2018
Journal: Sci Rep
Title: Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes.
Volume: 8
Issue: 1
Pages: 5958
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Publication
25249008 | J:324511
First Author: Mohamed R
Year: 2014
Journal: J Mol Med (Berl)
Title: Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice.
Volume: 92
Issue: 12
Pages: 1245-56
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Publication
30785802 | J:292059
First Author: Wang M
Year: 2019
Journal: FASEB J
Title: High glucose-induced ubiquitination of G6PD leads to the injury of podocytes.
Volume: 33
Issue: 5
Pages: 6296-6310
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Publication
17595213 | J:125421
First Author: Iwakura H
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Effects of ghrelin administration on decreased growth hormone status in obese animals.
Volume: 293
Issue: 3
Pages: E819-25
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24820416 | J:223685
First Author: Kuramoto K
Year: 2014
Journal: Mol Cell Biol
Title: Deficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction.
Volume: 34
Issue: 14
Pages: 2721-31
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29975570 | J:289949
First Author: Al-Obaidi N
Year: 2019
Journal: FASEB J
Title: Galectin-1 is a new fibrosis protein in type 1 and type 2 diabetes.
Volume: 33
Issue: 1
Pages: 373-387
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21193740 | J:183498
First Author: Boström KI
Year: 2011
Journal: Circ Res
Title: Activation of vascular bone morphogenetic protein signaling in diabetes mellitus.
Volume: 108
Issue: 4
Pages: 446-57
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27528615 | J:236304
First Author: Chen Q
Year: 2016
Journal: Mol Cell Biol
Title: Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling.
Volume: 36
Issue: 20
Pages: 2645-54
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Publication
36943878 | J:353322
First Author: Liang W
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Peroxisome proliferator-activated receptor-α (PPARα) regulates wound healing and mitochondrial metabolism in the cornea.
Volume: 120
Issue: 13
Pages: e2217576120
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29434323 | J:263808
First Author: Kobayashi N
Year: 2018
Journal: Sci Rep
Title: CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake.
Volume: 8
Issue: 1
Pages: 2785
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23152292 | J:192346
First Author: Vallon V
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus.
Volume: 304
Issue: 2
Pages: F156-67
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20130530 | J:184276
First Author: Nicholas SB
Year: 2010
Journal: Kidney Int
Title: Critical role for osteopontin in diabetic nephropathy.
Volume: 77
Issue: 7
Pages: 588-600
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30293775 | J:272050
First Author: King BC
Year: 2019
Journal: Cell Metab
Title: Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation.
Volume: 29
Issue: 1
Pages: 202-210.e6
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23801577 | J:208951
First Author: Shirakawa J
Year: 2013
Journal: Diabetes
Title: Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
Volume: 62
Issue: 10
Pages: 3448-58
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22427566 | J:196849
First Author: Gambhir D
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
Volume: 53
Issue: 4
Pages: 2208-17
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Publication
26334030 | J:290333
First Author: Mohamed R
Year: 2016
Journal: J Am Soc Nephrol
Title: Low-Dose IL-17 Therapy Prevents and Reverses Diabetic Nephropathy, Metabolic Syndrome, and Associated Organ Fibrosis.
Volume: 27
Issue: 3
Pages: 745-65
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24003152 | J:201158
First Author: Hu Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction.
Volume: 110
Issue: 38
Pages: 15401-6
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Publication
21940783 | J:189473
First Author: Howard AC
Year: 2011
Journal: Diabetes
Title: A novel cellular defect in diabetes: membrane repair failure.
Volume: 60
Issue: 11
Pages: 3034-43
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37988162 | J:352008
 
First Author: Govindarajah V
Year: 2024
Journal: J Clin Invest
Title: Gestational diabetes in mice induces hematopoietic memory that affects the long-term health of the offspring.
Volume: 134
Issue: 2
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21258336 | J:168556
First Author: Liu J
Year: 2011
Journal: Nat Med
Title: Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein.
Volume: 17
Issue: 2
Pages: 206-10
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26395740 | J:246932
First Author: Berglund LM
Year: 2016
Journal: Diabetes
Title: Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.
Volume: 65
Issue: 1
Pages: 239-54
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29891593 | J:264629
First Author: Yuan C
Year: 2018
Journal: Diabetes
Title: Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice.
Volume: 67
Issue: 9
Pages: 1880-1891
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27283743 | J:247006
First Author: Oe Y
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Coagulation Factor Xa and Protease-Activated Receptor 2 as Novel Therapeutic Targets for Diabetic Nephropathy.
Volume: 36
Issue: 8
Pages: 1525-33
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Publication
33205073 | J:348114
First Author: Ma H
Year: 2020
Journal: Cell Rep Med
Title: Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction.
Volume: 1
Issue: 6
Pages: 100097
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24135141 | J:204683
First Author: Dugan LL
Year: 2013
Journal: J Clin Invest
Title: AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function.
Volume: 123
Issue: 11
Pages: 4888-99
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37878711 | J:342212
First Author: Liu C
Year: 2023
Journal: Sci Adv
Title: Inhibition of neutrophil extracellular trap formation alleviates vascular dysfunction in type 1 diabetic mice.
Volume: 9
Issue: 43
Pages: eadj1019
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23251343 | J:195671
First Author: Kador PF
Year: 2012
Journal: PLoS One
Title: Novel diabetic mouse models as tools for investigating diabetic retinopathy.
Volume: 7
Issue: 12
Pages: e49422
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37480416 | J:339781
First Author: Riahi Y
Year: 2023
Journal: Diabetologia
Title: Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.
Volume: 66
Issue: 10
Pages: 1925-1942
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16923392 | J:115988
First Author: Oyadomari S
Year: 2006
Journal: Cell
Title: Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.
Volume: 126
Issue: 4
Pages: 727-39
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30412050 | J:272206
   
First Author: Riahi Y
Year: 2018
Journal: Elife
Title: Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse.
Volume: 7
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24463424 | J:210841
First Author: McBride JD
Year: 2014
Journal: J Invest Dermatol
Title: Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling.
Volume: 134
Issue: 6
Pages: 1725-1734
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Publication
22297487 | J:196754
First Author: Vagaja NN
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Changes in murine hyalocytes are valuable early indicators of ocular disease.
Volume: 53
Issue: 3
Pages: 1445-51
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Publication
29211853 | J:257095
First Author: Zhao S
Year: 2018
Journal: Endocrinology
Title: Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice.
Volume: 159
Issue: 2
Pages: 836-852
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Publication
28017717 | J:241963
First Author: Yamamoto Y
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Preserving expression of Pdx1 improves β-cell failure in diabetic mice.
Volume: 483
Issue: 1
Pages: 418-424
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Publication
27936229 | J:250973
First Author: Guihard PJ
Year: 2016
Journal: PLoS One
Title: Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice.
Volume: 11
Issue: 12
Pages: e0167936
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Publication
20547975 | J:169349
First Author: Schrufer TL
Year: 2010
Journal: Diabetes
Title: Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.
Volume: 59
Issue: 9
Pages: 2107-16
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Publication
30862678 | J:273782
First Author: Denhez B
Year: 2019
Journal: Diabetes
Title: Diabetes-Induced DUSP4 Reduction Promotes Podocyte Dysfunction and Progression of Diabetic Nephropathy.
Volume: 68
Issue: 5
Pages: 1026-1039
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Publication
34547510 | J:333665
 
First Author: Kitakaze K
Year: 2021
Journal: Mol Metab
Title: ATF4-mediated transcriptional regulation protects against β-cell loss during endoplasmic reticulum stress in a mouse model.
Volume: 54
Pages: 101338
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