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Search results 301 to 400 out of 670 for Iqgap1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4417313
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825613
Age: embryonic day 14.5
Image: euxassay_010153_15
Specimen Label: euxassay_010153_15
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:4417313
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825613
Age: embryonic day 14.5
Image: euxassay_010153_16
Specimen Label: euxassay_010153_16
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4417313
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825613
Age: embryonic day 14.5
Image: euxassay_010153_17
Specimen Label: euxassay_010153_17
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:4417313
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825613
Age: embryonic day 14.5
Image: euxassay_010153_18
Specimen Label: euxassay_010153_18
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:4417313
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825613
Age: embryonic day 14.5
Image: euxassay_010153_19
Specimen Label: euxassay_010153_19
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:4417313
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825613
Age: embryonic day 14.5
Image: euxassay_010153_20
Specimen Label: euxassay_010153_20
Detected: true
Specimen Num: 19
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Publication
- | J:63521
   
First Author: Bernards A
Year: 2000
Journal: GenBank Submission
Title: Mus musculus IQ motif containing GTPase activating protein 1 (Iqgap1) mRNA, complete cds
Pages: AF240630
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UniProt Feature
UniProt Feature
Begin: 2
Description: Ras GTPase-activating-like protein IQGAP1
Type: chain
End: 1657
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Protein
Q05CQ4
Organism: Mus musculus/domesticus
Length: 943  
Fragment?: true
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Protein
Q8CGH5
Organism: Mus musculus/domesticus
Length: 939  
Fragment?: true
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Publication
14516655 | J:81328
 
First Author: Natale DR
Year: 2002
Journal: Mech Dev
Title: Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development.
Volume: 119 Suppl 1
Pages: S21-6
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Publication
15457341 | J:93072
First Author: Cupit LD
Year: 2004
Journal: Mamm Genome
Title: Distinct PAR/IQGAP expression patterns during murine development: implications for thrombin-associated cytoskeletal reorganization.
Volume: 15
Issue: 8
Pages: 618-29
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Publication
31080134 | J:284491
First Author: Pepe-Mooney BJ
Year: 2019
Journal: Cell Stem Cell
Title: Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Volume: 25
Issue: 1
Pages: 23-38.e8
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Publication
24080911 | J:202007
First Author: Enger TB
Year: 2013
Journal: Lab Invest
Title: The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren's syndrome.
Volume: 93
Issue: 11
Pages: 1203-18
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Publication
24960163 | J:213780
First Author: Garg A
Year: 2014
Journal: J Clin Invest
Title: KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.
Volume: 124
Issue: 8
Pages: 3529-39
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Publication
36792666 | J:333810
First Author: Elenbaas JS
Year: 2023
Journal: Nat Commun
Title: SVEP1 is an endogenous ligand for the orphan receptor PEAR1.
Volume: 14
Issue: 1
Pages: 850
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Publication
20392836 | J:168516
First Author: Gordon FE
Year: 2010
Journal: Endocrinology
Title: Increased expression of angiogenic genes in the brains of mouse meg3-null embryos.
Volume: 151
Issue: 6
Pages: 2443-52
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Publication
18604197 | J:145651
First Author: Nojima H
Year: 2008
Journal: Nat Cell Biol
Title: IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.
Volume: 10
Issue: 8
Pages: 971-8
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Publication
34050187 | J:307868
First Author: Mohammed Y
Year: 2021
Journal: NPJ Syst Biol Appl
Title: Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.
Volume: 7
Issue: 1
Pages: 25
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Publication
30733279 | J:272586
 
First Author: Suzuki T
Year: 2019
Journal: Development
Title: Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.
Volume: 146
Issue: 4
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Publication
16510873 | J:105811
First Author: Wu X
Year: 2006
Journal: Genes Dev
Title: Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.
Volume: 20
Issue: 5
Pages: 571-85
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Publication
19000842 | J:142800
First Author: Brunskill EW
Year: 2008
Journal: Dev Cell
Title: Atlas of gene expression in the developing kidney at microanatomic resolution.
Volume: 15
Issue: 5
Pages: 781-91
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
14621295 | J:86686
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q9JKF1
Organism: Mus musculus/domesticus
Length: 1657  
Fragment?: false
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Publication
22328503 | J:197301
First Author: Tekletsadik YK
Year: 2012
Journal: J Cell Sci
Title: A conserved role of IQGAP1 in regulating TOR complex 1.
Volume: 125
Issue: Pt 8
Pages: 2041-52
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Publication
19956712 | -
First Author: McLaughlin LM
Year: 2009
Journal: PLoS Pathog
Title: The Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migration.
Volume: 5
Issue: 11
Pages: e1000671
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Protein
A0A0U1RNG5
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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Protein
A0A0U1RPU3
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
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Protein
A0A0U1RPI2
Organism: Mus musculus/domesticus
Length: 37  
Fragment?: true
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Publication
26195666 | J:227292
First Author: Bamidele AO
Year: 2015
Journal: J Cell Biol
Title: IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes.
Volume: 210
Issue: 2
Pages: 257-72
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Publication
24747073 | J:219456
First Author: Foroutannejad S
Year: 2014
Journal: Biochem Biophys Res Commun
Title: A novel role for IQGAP1 protein in cell motility through cell retraction.
Volume: 448
Issue: 1
Pages: 39-44
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Publication
30811216 | J:292003
First Author: Wang Z
Year: 2019
Journal: FASEB J
Title: Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation.
Volume: 33
Issue: 6
Pages: 6713-6725
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Publication
37597406 | J:339666
 
First Author: An C
Year: 2023
Journal: Int Immunopharmacol
Title: IQGAP1 promotes mitochondrial damage and activation of the mtDNA sensor cGAS-STING pathway to induce endothelial cell pyroptosis leading to atherosclerosis.
Volume: 123
Pages: 110795
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Interaction Experiment
Kholmanskikh SS (2006)
Description: Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility.
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Allele
Iqgap1<em1Smoc> | MGI:7290562
Name: IQ motif containing GTPase activating protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
15355962 | -
First Author: Grohmanova K
Year: 2004
Journal: J Biol Chem
Title: Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator.
Volume: 279
Issue: 47
Pages: 48495-504
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Publication
23982733 | -
First Author: Choi S
Year: 2013
Journal: EMBO J
Title: IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.
Volume: 32
Issue: 19
Pages: 2617-30
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Publication
16968698 | -
First Author: Lin Q
Year: 2006
Journal: J Biol Chem
Title: Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42.
Volume: 281
Issue: 46
Pages: 35253-62
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Strain
MGI:7623405 | C57BL/6JSmoc-Iqgap1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein
Q3TU73
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: true
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Protein
Q811L1
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: true
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Protein
Q8CC64
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Publication
9635188 | -
First Author: Eng K
Year: 1998
Journal: Curr Biol
Title: Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body.
Volume: 8
Issue: 11
Pages: 611-21
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Protein Domain
IPR000593 | RasGAP_C
Type: Domain
Description: This domain can be found in the C terminus of the IQGAP family members, including human IQGAP1/2/3, S. cerevisiae Iqg1 and S. pombe Rng2. Some members function in cytoskeletal remodelling []. Human IQGAP1 is a scaffolding protein that can assemble multi-protein complexes involved in cell-cell interaction, cell adherence, and movement via actin/tubulin-based cytoskeletal reorganization []. IQGAP1 is also a regulator of the MAPK and Wnt/beta-catenin signaling pathways []. Iqg1 and Rng2 are required for actomyosin ring construction during cytokinesis [, ].
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Protein
A0A1W2P841
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
A0A1W2P7Y0
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Publication
23509069 | -
First Author: Zhu M
Year: 2013
Journal: J Cell Biol
Title: MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.
Volume: 200
Issue: 6
Pages: 773-87
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Publication
29679050 | -
First Author: Vodicska B
Year: 2018
Journal: Sci Rep
Title: MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression.
Volume: 8
Issue: 1
Pages: 6330
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Protein Domain
IPR042779 | MISP/MISP3
Type: Family
Description: This entry includes MISP/MISP3 from animals. MISP is an actin-binding protein that functions in spindle orientation probably by linking the astral microtubules (MTs) to the actin cytoskeleton [, ]. It has been shown to regulate IQGAP1 and Cdc42 to ensure proper mitotic progression and correct spindle orientation []. The function of MISP3 is not clear.
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Protein
Q9D279
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
F6WBA1
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
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Protein
A0A087WQC3
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
A0A087WQV6
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Protein
Q9CVC4
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein
A0A087WR51
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
A0A087WQ89
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: false
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Publication
23574715 | -
First Author: Maier B
Year: 2013
Journal: Cell Cycle
Title: The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells.
Volume: 12
Issue: 9
Pages: 1457-71
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Publication
20335501 | -
First Author: Applewhite DA
Year: 2010
Journal: Mol Biol Cell
Title: The spectraplakin Short stop is an actin-microtubule cross-linker that contributes to organization of the microtubule network.
Volume: 21
Issue: 10
Pages: 1714-24
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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