|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 488 for Irs1

<< First    < Previous  |  Next >    Last >>
0.019s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:55264
   
First Author: Chernausek SD
Year: 1999
Title: Insulin-like growth factor control of growth - Insights from targeted disruption of murine genes and from human disease.
Volume: 10
Pages: 11-21
•
•
•
•
•
Publication
15169905 | J:91027
First Author: Ueki K
Year: 2004
Journal: Mol Cell Biol
Title: Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.
Volume: 24
Issue: 12
Pages: 5434-46
•
•
•
•
•
Publication
12832401 | J:91698
First Author: Widberg CH
Year: 2003
Journal: J Biol Chem
Title: Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation.
Volume: 278
Issue: 37
Pages: 35093-101
•
•
•
•
•
Publication
27708159 | J:236520
First Author: Zhang Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Volume: 113
Issue: 42
Pages: E6418-E6426
•
•
•
•
•
Publication
28591635 | J:256190
First Author: Hine C
Year: 2017
Journal: Cell Metab
Title: Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.
Volume: 25
Issue: 6
Pages: 1320-1333.e5
•
•
•
•
•
Publication
12904469 | J:84857
First Author: Schubert M
Year: 2003
Journal: J Neurosci
Title: Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation.
Volume: 23
Issue: 18
Pages: 7084-92
•
•
•
•
•
Publication
10471495 | J:57319
First Author: Withers DJ
Year: 1999
Journal: Nat Genet
Title: Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
Volume: 23
Issue: 1
Pages: 32-40
•
•
•
•
•
Publication
18256806 | J:137955
First Author: Tsuneki H
Year: 2008
Journal: Diabetologia
Title: Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice.
Volume: 51
Issue: 4
Pages: 657-67
•
•
•
•
•
Publication
21321084 | J:170999
First Author: Goorden SM
Year: 2011
Journal: Mol Cell Biol
Title: Rheb is essential for murine development.
Volume: 31
Issue: 8
Pages: 1672-8
•
•
•
•
•
Publication
9229117 | J:41474
First Author: Naggert J
Year: 1997
Journal: Curr Opin Genet Dev
Title: The genetics of obesity.
Volume: 7
Issue: 3
Pages: 398-404
•
•
•
•
•
Publication
9624169 | J:48179
First Author: Yamauchi T
Year: 1998
Journal: J Biol Chem
Title: Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase.
Volume: 273
Issue: 25
Pages: 15719-26
•
•
•
•
•
Publication
35806430 | J:326543
 
First Author: Jiang A
Year: 2022
Journal: Int J Mol Sci
Title: G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle.
Volume: 23
Issue: 13
•
•
•
•
•
Publication
17662267 | J:124667
First Author: Heckman BM
Year: 2007
Journal: Dev Biol
Title: Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.
Volume: 309
Issue: 1
Pages: 137-49
•
•
•
•
•
Publication
22288475 | J:184234
First Author: Chirivella L
Year: 2012
Journal: Eur J Neurosci
Title: IRS2 signalling is required for the development of a subset of sensory spinal neurons.
Volume: 35
Issue: 3
Pages: 341-52
•
•
•
•
•
Publication
15587270 | J:94589
First Author: Lamotte L
Year: 2004
Journal: Transgenic Res
Title: Knock-in of diphteria toxin A chain gene at Ins2 locus: effects on islet development and localization of Ins2 expression in the brain.
Volume: 13
Issue: 5
Pages: 463-73
•
•
•
•
•
Publication
15249583 | J:91846
First Author: Harrington LS
Year: 2004
Journal: J Cell Biol
Title: The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.
Volume: 166
Issue: 2
Pages: 213-23
•
•
•
•
•
Publication
16455755 | J:107908
First Author: Fecchi K
Year: 2006
Journal: FASEB J
Title: Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.
Volume: 20
Issue: 6
Pages: 705-7
•
•
•
•
•
Publication
19357198 | J:149326
First Author: Pollizzi K
Year: 2009
Journal: Hum Mol Genet
Title: A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles.
Volume: 18
Issue: 13
Pages: 2378-87
•
•
•
•
•
Publication
11897712 | J:106827
First Author: Duvillié B
Year: 2002
Journal: Endocrinology
Title: Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin.
Volume: 143
Issue: 4
Pages: 1530-7
•
•
•
•
•
Publication
14502571 | J:86157
First Author: Umans L
Year: 2003
Journal: Genesis
Title: Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse.
Volume: 37
Issue: 1
Pages: 5-11
•
•
•
•
•
Publication
39716738 | J:360072
 
First Author: Basu S
Year: 2024
Journal: Cereb Cortex
Title: Identification of Pappa and Sall3 as Gli3 direct target genes acting downstream of cilia signaling in corticogenesis.
Volume: 34
Issue: 12
•
•
•
•
•
Publication
19228596 | J:152946
First Author: Sferruzzi-Perri AN
Year: 2009
Journal: Biol Reprod
Title: Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.
Volume: 81
Issue: 1
Pages: 207-21
•
•
•
•
•
Publication
29728617 | J:262992
First Author: Zhuang L
Year: 2018
Journal: Nat Commun
Title: Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.
Volume: 9
Issue: 1
Pages: 1796
•
•
•
•
•
Publication
21238928 | J:168571
First Author: Zou J
Year: 2011
Journal: Dev Cell
Title: Rheb1 is required for mTORC1 and myelination in postnatal brain development.
Volume: 20
Issue: 1
Pages: 97-108
•
•
•
•
•
Publication
35377412 | J:333870
First Author: Jazwiec PA
Year: 2022
Journal: Biol Reprod
Title: Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism†.
Volume: 107
Issue: 2
Pages: 574-589
•
•
•
•
•
Publication
23907538 | J:203690
First Author: Martinez-Lopez N
Year: 2013
Journal: EMBO Rep
Title: Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development.
Volume: 14
Issue: 9
Pages: 795-803
•
•
•
•
•
Publication
27534441 | J:234901
 
First Author: Potter PK
Year: 2016
Journal: Nat Commun
Title: Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Volume: 7
Pages: 12444
•
•
•
•
•
Publication
15760467 | J:99477
 
First Author: Brown AC
Year: 2005
Journal: BMC Genet
Title: Searching QTL by gene expression: analysis of diabesity.
Volume: 6
Pages: 12
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
•
•
•
•
•
Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
•
•
•
•
•
Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
•
•
•
•
•
Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
17579213 | J:125398
First Author: Giraud J
Year: 2007
Journal: Mol Endocrinol
Title: Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.
Volume: 21
Issue: 9
Pages: 2294-302
•
•
•
•
•
Allele
Irs1<tm2Mfw> | MGI:7562477
 
Name: insulin receptor substrate 1; targeted mutation 2, Morris F White
Allele Type: Targeted
•
•
•
•
•
HT Experiment
E-MEXP-1649 | Transcription profiling of mouse liver cells with liver specific deletion of Irs1 and/or Irs2 and Foxo1during fasting and feeding
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
27217486 | J:249699
First Author: Katagiri S
Year: 2016
Journal: Diabetes
Title: Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance.
Volume: 65
Issue: 9
Pages: 2760-71
•
•
•
•
•
Publication
16914728 | J:112131
First Author: Shah OJ
Year: 2006
Journal: Mol Cell Biol
Title: Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis.
Volume: 26
Issue: 17
Pages: 6425-34
•
•
•
•
•
Publication
22033112 | -
First Author: Shi J
Year: 2011
Journal: Dev Cell
Title: The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling.
Volume: 21
Issue: 5
Pages: 835-47
•
•
•
•
•
Interaction Experiment
Shi J (2011)
Description: The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling.
•
•
•
•
•
Allele
Irs1<em1Smoc> | MGI:7290584
Name: insulin receptor substrate 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Tg(IRS1)1Mhep | MGI:3056765
Name: transgene insertion 1, Rolf Carlson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:6429004 | C57BL/6JSmoc-Irs1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Publication
29736736 | J:327287
First Author: Sposato V
Year: 2019
Journal: Mol Neurobiol
Title: The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation.
Volume: 56
Issue: 1
Pages: 535-552
•
•
•
•
•
Strain
MGI:3835499 | FVB-Tg(IRS1)1Mhep
Attribute String: coisogenic, transgenic
•
•
•
•
•
Strain
MGI:2164458 | FVB-Tg(IRS1)1Mhep/J
Attribute String: mutant strain, transgenic
•
•
•
•
•
Publication
9303488 | J:92999
First Author: Tanaka S
Year: 1997
Journal: Hepatology
Title: Biological effects of human insulin receptor substrate-1 overexpression in hepatocytes.
Volume: 26
Issue: 3
Pages: 598-604
•
•
•
•
•
Publication
16564107 | J:110645
First Author: de la Monte SM
Year: 2006
Journal: J Hepatol
Title: Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness.
Volume: 44
Issue: 5
Pages: 971-83
•
•
•
•
•
Allele
Tg(Myl2-IRS1*)7Shlm | MGI:3772658
Name: transgene insertion 7, Gerald Shulman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(IRS1)1Mhep/?
Background: FVB-Tg(IRS1)1Mhep
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Allele
Irs1<m2Btlr> | MGI:6268722
Name: insulin receptor substrate 1; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
•
•
•
•
•
Strain
MGI:6268723 | C57BL/6J-Irs1<m2Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Irs1/Irs1
Background: C57BL/6J-Irs1
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein Domain
IPR028423 | SOCS7
Type: Family
Description: SOCS7 is a member of the suppressor of cytokine signaling family of proteins. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation []. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA [].
•
•
•
•
•
Protein Domain
IPR035866 | SOCS7_SH2
Type: Domain
Description: SOCS7 is a member of the suppressor of cytokine signaling family of proteins. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation []. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA [].This entry represents the SH2 domain of SOCS7.
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(IRS1)1Mhep/? Tg(SERPINA1-HBVX)1655Jtsb/?
Background: involves: C3H * C57BL/6 * FVB * ICR
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
24076600 | J:205290
First Author: Sartori R
Year: 2013
Journal: Nat Genet
Title: BMP signaling controls muscle mass.
Volume: 45
Issue: 11
Pages: 1309-18
•
•
•
•
•
Publication
17928169 | J:172978
First Author: Ye J
Year: 2007
Journal: Gene
Title: FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy.
Volume: 404
Issue: 1-2
Pages: 53-60
•
•
•
•
•
Protein Domain
IPR031890 | Fbxo30/Fbxo40
Type: Family
Description: This entry includes F-box only protein 30 (Fbxo30) []and F-box only protein 40 (Fbxo40) []. Fbxo30 is a ubiquitin ligase required for muscle loss, hence it is also known as muscle ubiquitin ligase of the SCF complex in atrophy-1 (MUSA1) []. Fbxo40 id an E3 ubiquitin ligase that induces IRS1 ubiquitination and breakdown specifically in skeletal muscle cells and only upon IGF1 (insulin-like growth factor 1) stimulation [].
•
•
•
•
•
Publication
15677474 | -
First Author: Martens N
Year: 2005
Journal: J Biol Chem
Title: Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation.
Volume: 280
Issue: 14
Pages: 13817-23
•
•
•
•
•
HT Experiment
E-MTAB-4989 | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Protein Domain
IPR037346 | SOCS7_SOCS
Type: Domain
Description: This entry represents the SOCS box domain of SOCS7.SOCS7 is a member of the suppressor of cytokine signaling family of proteins. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation []. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA [].The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The SOCS box interacts with Elongins B and C, Cullin-5 or Cullin-2, Rbx-1, and E2. Therefore, SOCS-box-containing proteins probably function as E3 ubiquitin ligases and mediate the degradation of proteins associated through their N-terminal regions [, ].
•
•
•
•
•
HT Experiment
GSE135007 | Giant island mice exhibit widespread gene regulatory evolution in key metabolic organs
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
•
•
•
•
•
Publication
9628903 | J:48438
First Author: Cartwright R
Year: 1998
Journal: Nucleic Acids Res
Title: The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family.
Volume: 26
Issue: 13
Pages: 3084-9
•
•
•
•
•
Publication
21123564 | J:166745
First Author: Koch C
Year: 2010
Journal: J Neurosci
Title: Leptin rapidly improves glucose homeostasis in obese mice by increasing hypothalamic insulin sensitivity.
Volume: 30
Issue: 48
Pages: 16180-7
•
•
•
•
•
Publication
22405072 | J:182672
First Author: Tsuchiya K
Year: 2012
Journal: Cell Metab
Title: FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.
Volume: 15
Issue: 3
Pages: 372-81
•
•
•
•
•
Publication
35940125 | J:328246
 
First Author: Rousseau M
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Reduction of DUSP4 contributes to podocytes oxidative stress, insulin resistance and diabetic nephropathy.
Volume: 624
Pages: 127-133
•
•
•
•
•
Publication
14693698 | J:87249
First Author: Kushner JA
Year: 2004
Journal: Diabetes
Title: Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice.
Volume: 53
Issue: 1
Pages: 61-6
•
•
•
•
•
Publication
19564410 | J:152617
First Author: Standen CL
Year: 2009
Journal: Mol Cell Biol
Title: Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.
Volume: 29
Issue: 17
Pages: 4831-40
•
•
•
•
•
Publication
25799226 | J:228178
First Author: Wu Y
Year: 2015
Journal: Nat Med
Title: Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.
Volume: 21
Issue: 4
Pages: 373-82
•
•
•
•
•
Publication
27634043 | J:314799
First Author: Lykken EA
Year: 2016
Journal: J Biol Chem
Title: The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling.
Volume: 291
Issue: 45
Pages: 23532-23544
•
•
•
•
•
Publication
25077541 | J:310693
 
First Author: Du WW
Year: 2014
Journal: Cell Death Dis
Title: miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7.
Volume: 5
Pages: e1355
•
•
•
•
•
Publication
15226403 | -
First Author: Motegi A
Year: 2004
Journal: J Cell Sci
Title: ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.
Volume: 117
Issue: Pt 15
Pages: 3319-29
•
•
•
•
•
Publication
11121404 | -
First Author: Souttou B
Year: 2001
Journal: J Biol Chem
Title: Activation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathway.
Volume: 276
Issue: 12
Pages: 9526-31
•
•
•
•
•
Publication
17274988 | -
First Author: Degoutin J
Year: 2007
Journal: FEBS Lett
Title: ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation.
Volume: 581
Issue: 4
Pages: 727-34
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom