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Search results 301 to 393 out of 393 for Izumo1

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Type Details Score
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_263977
Specimen Label: RBRC_263977
Specimen Num: 28
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264131
Specimen Label: RBRC_264131
Specimen Num: 70
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264133
Specimen Label: RBRC_264133
Specimen Num: 71
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264135
Specimen Label: RBRC_264135
Specimen Num: 72
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264039
Specimen Label: RBRC_264039
Specimen Num: 104
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264041
Specimen Label: RBRC_264041
Specimen Num: 105
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264043
Specimen Label: RBRC_264043
Specimen Num: 106
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264213
Specimen Label: RBRC_264213
Specimen Num: 146
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264215
Specimen Label: RBRC_264215
Specimen Num: 147
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264217
Specimen Label: RBRC_264217
Specimen Num: 148
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_263941
Specimen Label: RBRC_263941
Specimen Num: 10
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Female
Emaps: EMAPS:1915328
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264083
Specimen Label: RBRC_264083
Detected: false
Specimen Num: 46
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264013
Specimen Label: RBRC_264013
Specimen Num: 91
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264173
Specimen Label: RBRC_264173
Specimen Num: 126
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264005
Specimen Label: RBRC_264005
Specimen Num: 42
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264007
Specimen Label: RBRC_264007
Specimen Num: 43
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264167
Specimen Label: RBRC_264167
Specimen Num: 88
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_263999
Specimen Label: RBRC_263999
Detected: true
Specimen Num: 39
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264001
Specimen Label: RBRC_264001
Detected: true
Specimen Num: 40
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264157
Specimen Label: RBRC_264157
Detected: true
Specimen Num: 83
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264159
Specimen Label: RBRC_264159
Detected: true
Specimen Num: 84
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264161
Specimen Label: RBRC_264161
Detected: true
Specimen Num: 85
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264163
Specimen Label: RBRC_264163
Detected: true
Specimen Num: 86
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Female
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_263943
Specimen Label: RBRC_263943
Detected: false
Specimen Num: 11
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Female
Emaps: EMAPS:1881228
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264085
Specimen Label: RBRC_264085
Detected: false
Specimen Num: 47
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264015
Specimen Label: RBRC_264015
Specimen Num: 92
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692255
Age: postnatal adult
Image: RBRC_264175
Specimen Label: RBRC_264175
Specimen Num: 127
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Allele
Izumo1r<tm1Salb> | MGI:3512121
Name: IZUMO1 receptor, JUNO; targeted mutation 1, J Michael Salbaum
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Izumo1r<tm1e(KOMP)Wtsi> | MGI:4362135
Name: IZUMO1 receptor, JUNO; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Izumo1r<tm2a(KOMP)Wtsi> | MGI:4363787
Name: IZUMO1 receptor, JUNO; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Izumo1r<tm1a(KOMP)Wtsi> | MGI:4364095
Name: IZUMO1 receptor, JUNO; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Izumo1r<tm2e(KOMP)Wtsi> | MGI:4364970
Name: IZUMO1 receptor, JUNO; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Izumo1r<tm1.1Salb> | MGI:5538512
Name: IZUMO1 receptor, JUNO; targeted mutation 1.1, J Michael Salbaum
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Izumo1r<tm1b(KOMP)Wtsi> | MGI:5548704
Name: IZUMO1 receptor, JUNO; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Izumo1r<tm2c(KOMP)Wtsi> | MGI:5792910
Name: IZUMO1 receptor, JUNO; targeted mutation 2c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Izumo1r<em1Nino> | MGI:6511751
Name: IZUMO1 receptor, JUNO; endonuclease-mediated mutation 1, Naokazu Inoue
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s), Null/knockout
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Allele
Tg(Clgn-Izumo1/mCherry)1Osb | MGI:6325010
Name: transgene insertion 1, Research Institute for Microbial Diseases, Osaka University
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:5605043 | B6.129P2-Izumo1r<tm1Salb>/Mmmh
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6122296 | C57BL/6N-A<tm1Brd> Izumo1r<tm2a(KOMP)Wtsi>/WtsiOrl
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5700693 | C57BL/6N-Izumo1r<tm2a(KOMP)Wtsi>/Wtsi
Attribute String: coisogenic, targeted mutation
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Strain
MGI:6146302 | C57BL/6N-Izumo1r<tm1a(KOMP)Wtsi>/F07Rbrc
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5538690 | B6.129P2(Cg)-Izumo1r<tm1.1Salb>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5538539 | B6.129P2(Cg)-Izumo1r<tm1.1Salb>/Mmnc
Attribute String: mutant strain, targeted mutation, congenic
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Strain
MGI:6146373 | C57BL/6N-Izumo1r<tm1b(KOMP)Wtsi>/F07Rbrc
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5630550 | C57BL/6N-Izumo1r<tm1b(KOMP)Wtsi>/Rbrc
Attribute String: coisogenic, targeted mutation
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Allele
Izumo1r<em1Osb> | MGI:6343374
Name: IZUMO1 receptor, JUNO; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7507305 | B6;D2-Izumo1r<em1Nino>/NinoRbrc
Attribute String: endonuclease-mediated mutation, mutant stock
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: B6.129P2(Cg)-Izumo1r
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: involves: C57BL/6N * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: C57BL/6N-Izumo1r/Rbrc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r
Background: C57BL/6N-Izumo1r/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Publication
27374339 | -
First Author: Nishimura K
Year: 2016
Journal: Curr Biol
Title: The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins.
Volume: 26
Issue: 14
Pages: R661-2
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Protein
Q9EQF4
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein
Q9EQF4-2
Organism: Mus musculus/domesticus
Length: 280  
Fragment?: false
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Strain
MGI:5557193 | B6NTac;B6N-A<tm1Brd> Izumo1r<tm2a(KOMP)Wtsi>/Wtsi
Attribute String: mutant strain, targeted mutation
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Strain
MGI:6334071 | B6;D2-Izumo1r<em1Osb>/Osb
Attribute String: mutant strain, endonuclease-mediated mutation
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Strain
MGI:7507258 | B6;D2-Izumo1r<em1Osb>/OsbRbrc
Attribute String: endonuclease-mediated mutation, mutant stock
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Genotype
Genotype
Symbol: Izumo1r/Izumo1r<+>
Background: C57BL/6N-Izumo1r/Rbrc
Zygosity: ht
Has Mutant Allele: true
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Publication
11111049 | J:66219
First Author: Spiegelstein O
Year: 2000
Journal: Gene
Title: Identification of two putative novel folate receptor genes in humans and mouse.
Volume: 258
Issue: 1-2
Pages: 117-25
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Allele
Tg(Clgn-Izumo1/EYFP1*)1Nino | MGI:7435158
Name: transgene insertion 1, Naokazu Inoue
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:6353573 | B6;D2-Tg(Clgn-Izumo1/EYFP1*)1Nino/Nino
Attribute String: mutant strain, transgenic
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Publication
22365888 | J:184371
First Author: Cherukad J
Year: 2012
Journal: Placenta
Title: Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.
Volume: 33
Issue: 5
Pages: 440-8
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Protein Domain
IPR032699 | Izumo-Ig
Type: Domain
Description: This is the immunoglobulin domain on Izumo proteins from higher eukaryotes. Izumo is a typical type I membrane glycoprotein with one immunoglobulin-like domain and a putative N-glycoside link motif - glycosylation site. The full-length human IZUMO1 protein is a molecule with a single immunoglobulin (Ig) domain. It is thought that Izumo proteins bind to putative Izumo receptors on the oocyte. Izumo is not detectable on the surface of fresh sperm but becomes exposed only after an exocytotic process, the acrosome reaction, has occurred. Studies have shown that knock-out mice (Izumo-/- males) were sterile despite normal mating behaviour and ejaculation, indicating the importance of the protein in fertilisation []. There are cysteine residues thought to form a disulphide bridge. Izumo is a typical type I membrane glycoprotein with one immunoglobulin-like domain and a putative N-glycoside link motif (Asn 204) []. There is a conserved GCL sequence motif. Izumo expression has been found to be testis-specific [, ].
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Strain
MGI:6354184 | STOCK Izumo1<tm1Osb> Tg(Clgn-Izumo1/mCherry)1Osb Tg(CAG-EGFP,Acr-EGFP)2Osb/OsbRbrc
Attribute String: transgenic, mutant stock, targeted mutation
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Publication
32484434 | J:289090
   
First Author: Lamas-Toranzo I
Year: 2020
Journal: Elife
Title: TMEM95 is a sperm membrane protein essential for mammalian fertilization.
Volume: 9
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Publication
32210282 | J:289097
First Author: Barbaux S
Year: 2020
Journal: Sci Rep
Title: Sperm SPACA6 protein is required for mammalian Sperm-Egg Adhesion/Fusion.
Volume: 10
Issue: 1
Pages: 5335
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Publication
31575859 | J:281966
First Author: Rival CM
Year: 2019
Journal: Nat Commun
Title: Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization.
Volume: 10
Issue: 1
Pages: 4456
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Publication
23213457 | J:185340
First Author: Ohnami N
Year: 2012
Journal: Biol Open
Title: CD81 and CD9 work independently as extracellular components upon fusion of sperm and oocyte.
Volume: 1
Issue: 7
Pages: 640-7
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Publication
32393636 | J:289149
First Author: Noda T
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice.
Volume: 117
Issue: 21
Pages: 11493-11502
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Publication
32295885 | J:287619
First Author: Fujihara Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice.
Volume: 117
Issue: 17
Pages: 9393-9400
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Publication
24275887 | J:216863
First Author: Lorenzetti D
Year: 2014
Journal: Mamm Genome
Title: A transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusion.
Volume: 25
Issue: 3-4
Pages: 141-8
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Publication
30328350 | J:285739
First Author: Ito C
Year: 2018
Journal: Reproduction
Title: Deletion of Eqtn in mice reduces male fertility and sperm-egg adhesion.
Volume: 156
Issue: 6
Pages: 579-590
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Publication
21339297 | J:171133
First Author: Marcello MR
Year: 2011
Journal: J Biol Chem
Title: Lack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal sperm.
Volume: 286
Issue: 15
Pages: 13060-70
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Publication
36050562 | J:328830
First Author: Hao H
Year: 2022
Journal: Mol Biomed
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