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Search results 301 to 365 out of 365 for Kap

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Hits by Pathway

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Hits by Strain

Type Details Score
Allele
Tg(Kap-REN)12403/1Sig | MGI:7788375
Name: transgene insertion 12403/1, Curt Sigmund
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Atg5/Atg5 Tg(Kap-cre)1Isa/?
Background: involves: 129S/SvEv * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Allele
Tg(Kap-icre)29066/2Sig | MGI:3806307
Name: transgene insertion 29066/2, Curt Sigmund
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Publication
9013890 | J:38131
First Author: Mori K
Year: 1997
Journal: FEBS Lett
Title: Molecular cloning of a novel mouse aspartic protease-like protein that is expressed abundantly in the kidney.
Volume: 401
Issue: 2-3
Pages: 218-22
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Publication
16257389 | J:102701
First Author: Iriuchijima N
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Reduced expression of kinase-associated phosphatase in cortical dendrites of MAP2-deficient mice.
Volume: 338
Issue: 2
Pages: 1216-21
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Publication
15704002 | J:174121
First Author: Kutok JL
Year: 2005
Journal: J Mol Histol
Title: The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice.
Volume: 36
Issue: 1-2
Pages: 77-87
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Publication
35658715 | J:360400
First Author: Jia P
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Chemokine CCL2 from proximal tubular epithelial cells contributes to sepsis-induced acute kidney injury.
Volume: 323
Issue: 2
Pages: F107-F119
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Publication
22518004 | J:264459
First Author: Matsusaka T
Year: 2012
Journal: J Am Soc Nephrol
Title: Liver angiotensinogen is the primary source of renal angiotensin II.
Volume: 23
Issue: 7
Pages: 1181-9
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Publication
31881660 | J:303308
 
First Author: Suzuki C
Year: 2019
Journal: Int J Mol Sci
Title: Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions.
Volume: 21
Issue: 1
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Publication
27304991 | J:294884
First Author: Li H
Year: 2016
Journal: Autophagy
Title: Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis.
Volume: 12
Issue: 9
Pages: 1472-86
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Publication
30874544 | J:293453
First Author: Peng X
Year: 2019
Journal: Cell Death Dis
Title: ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury.
Volume: 10
Issue: 4
Pages: 253
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Publication
37382161 | J:360959
First Author: Wu M
Year: 2023
Journal: Adv Sci (Weinh)
Title: TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Volume: 10
Issue: 25
Pages: e2301753
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Publication
25201884 | J:318630
First Author: Gall JM
Year: 2015
Journal: J Am Soc Nephrol
Title: Conditional knockout of proximal tubule mitofusin 2 accelerates recovery and improves survival after renal ischemia.
Volume: 26
Issue: 5
Pages: 1092-102
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Strain
MGI:3815459 | B6.Cg-Tg(Kap-icre)29066/2Sig/J
Attribute String: transgenic, congenic
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Publication
21753145 | J:178815
First Author: Li H
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Renal proximal tubule angiotensin AT1A receptors regulate blood pressure.
Volume: 301
Issue: 4
Pages: R1067-77
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Publication
27436577 | J:237858
First Author: Gjorgjieva M
Year: 2016
Journal: Hum Mol Genet
Title: Progressive development of renal cysts in glycogen storage disease type I.
Volume: 25
Issue: 17
Pages: 3784-3797
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Publication
36629048 | J:339745
First Author: Bai M
Year: 2023
Journal: EMBO Mol Med
Title: LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease.
Volume: 15
Issue: 2
Pages: e16581
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Publication
39405939 | J:358459
First Author: Huang W
Year: 2024
Journal: Int Immunopharmacol
Title: Ulinastatin attenuates renal ischemia-reperfusion injury by inhibiting NLRP3 inflammasome-triggered pyroptosis.
Volume: 143
Issue: Pt 1
Pages: 113306
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Genotype
Genotype
Symbol: Atg5/Atg5 Tg(Kap-icre)29066/2Sig/?
Background: involves: 129S/SvEv * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-cat,-lacZ)11Miya/? Tg(Kap-cre)1Isa/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Publication
11290294 | J:68213
First Author: Tkatchenko AV
Year: 2001
Journal: Development
Title: Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia.
Volume: 128
Issue: 9
Pages: 1547-58
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Publication
15385554 | J:95189
First Author: Pruett ND
Year: 2004
Journal: J Biol Chem
Title: Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.
Volume: 279
Issue: 49
Pages: 51524-33
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Publication
8524307 | J:30302
First Author: Bayer KU
Year: 1996
Journal: Mol Cell Biol
Title: An alternative, nonkinase product of the brain-specifically expressed Ca2+/calmodulin-dependent kinase II alpha isoform gene in skeletal muscle.
Volume: 16
Issue: 1
Pages: 29-36
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Publication
9449642 | J:45837
First Author: Melià MJ
Year: 1998
Journal: Endocrinology
Title: Identification of androgen-regulated genes in mouse kidney by representational difference analysis and random arbitrarily primed polymerase chain reaction.
Volume: 139
Issue: 2
Pages: 688-95
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Publication
9878246 | J:52082
First Author: Cole SE
Year: 1998
Journal: Genomics
Title: A cluster of keratin-associated proteins on mouse chromosome 10 in the region of conserved linkage with human chromosome 21.
Volume: 54
Issue: 3
Pages: 437-42
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Publication
12486089 | J:81118
First Author: Tzortzaki EG
Year: 2002
Journal: J Histochem Cytochem
Title: Gender- and age-dependent changes in kidney androgen protein mRNA expression in a knockout mouse model for nephrolithiasis.
Volume: 50
Issue: 12
Pages: 1663-9
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Publication
22344686 | J:183786
First Author: Chau BN
Year: 2012
Journal: Sci Transl Med
Title: MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Volume: 4
Issue: 121
Pages: 121ra18
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Strain
MGI:5569836 | B6.Cg-Gt(ROSA)26Sor<tm1Sor> Tg(Kap-icre)29066/2Sig
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
18385272 | J:137742
First Author: Li H
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: An androgen-inducible proximal tubule-specific Cre recombinase transgenic model.
Volume: 294
Issue: 6
Pages: F1481-6
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Publication
26732653 | J:259564
 
First Author: Takagi A
Year: 2016
Journal: Sci Rep
Title: Mammalian autophagy is essential for hepatic and renal ketogenesis during starvation.
Volume: 6
Pages: 18944
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Publication
39659245 | J:360136
First Author: Wang X
Year: 2024
Journal: FASEB J
Title: MiR-21 suppression in macrophages promotes M2-like polarization and attenuates kidney ischemia-reperfusion injury.
Volume: 38
Issue: 23
Pages: e70251
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Publication
11015555 | J:135870
First Author: Davisson RL
Year: 1999
Journal: Physiol Genomics
Title: Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice.
Volume: 1
Issue: 1
Pages: 3-9
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Publication
23732084 | J:203349
First Author: Liu S
Year: 2013
Journal: Toxicol Appl Pharmacol
Title: The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models.
Volume: 272
Issue: 1
Pages: 230-7
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Publication
38057332 | J:343494
First Author: Casemayou A
Year: 2023
Journal: Sci Rep
Title: Abcc6 deficiency prevents rhabdomyolysis-induced acute kidney injury.
Volume: 13
Issue: 1
Pages: 21513
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Publication
22265049 | J:179884
First Author: Takahashi A
Year: 2012
Journal: Am J Pathol
Title: Autophagy guards against cisplatin-induced acute kidney injury.
Volume: 180
Issue: 2
Pages: 517-25
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Publication
32989250 | J:307304
First Author: Nakamura S
Year: 2020
Journal: Nat Cell Biol
Title: LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury.
Volume: 22
Issue: 10
Pages: 1252-1263
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Kap-icre)29066/2Sig/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Kap-icre)29066/2Sig/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Kap-icre)29066/2Sig
Zygosity: cn
Has Mutant Allele: true
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Protein
Q920C4
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Protein
Q3TYT4
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
Q810H7
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Protein
Q53ZU3
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Publication
31040190 | J:292962
First Author: Sakai S
Year: 2019
Journal: J Am Soc Nephrol
Title: Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes.
Volume: 30
Issue: 6
Pages: 929-945
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Publication
27491826 | J:254095
 
First Author: Johansson E
Year: 2016
Journal: Sci Rep
Title: Simultaneous targeted activation of Notch1 and Vhl-disruption in the kidney proximal epithelial tubular cells in mice.
Volume: 6
Pages: 30739
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Publication
21493778 | J:179961
First Author: Kimura T
Year: 2011
Journal: J Am Soc Nephrol
Title: Autophagy protects the proximal tubule from degeneration and acute ischemic injury.
Volume: 22
Issue: 5
Pages: 902-13
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Publication
24956378 | J:216237
First Author: Liang L
Year: 2014
Journal: Mol Endocrinol
Title: Androgen receptor enhances kidney stone-CaOx crystal formation via modulation of oxalate biosynthesis & oxidative stress.
Volume: 28
Issue: 8
Pages: 1291-303
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Publication
26986194 | J:293019
First Author: Yamamoto T
Year: 2016
Journal: Autophagy
Title: Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.
Volume: 12
Issue: 5
Pages: 801-13
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Publication
27932476 | J:290894
First Author: Yamamoto T
Year: 2017
Journal: J Am Soc Nephrol
Title: High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney.
Volume: 28
Issue: 5
Pages: 1534-1551
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Publication
27292223 | J:315917
First Author: Ide N
Year: 2016
Journal: Kidney Int
Title: In vivo evidence for a limited role of proximal tubular Klotho in renal phosphate handling.
Volume: 90
Issue: 2
Pages: 348-362
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Publication
36649084 | J:336316
 
First Author: Nakamura J
Year: 2023
Journal: JCI Insight
Title: TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney.
Volume: 8
Issue: 4
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Publication
15075192 | J:95430
First Author: Lavoie JL
Year: 2004
Journal: Am J Physiol Renal Physiol
Title: Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule.
Volume: 286
Issue: 5
Pages: F965-71
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Publication
- | J:206504
     
First Author: Genetic Resource Science at The Jackson Laboratory
Year: 2014
Journal: Direct Data Submission from Genetic Resource Science
Title: Expression/Specificity Patterns of Cre Alleles, 2014
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom