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Search results 301 to 365 out of 365 for Kat2a

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Type Details Score
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Gene
694668 | GCAWKR
Type: gene
Organism: macaque, rhesus
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Gene
107968451 | GCAWKR
Type: gene
Organism: chimpanzee
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UniProt Feature
UniProt Feature
Begin: 2
Description: Histone acetyltransferase KAT2A
Type: chain
End: 830
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UniProt Feature
UniProt Feature
Begin: 98
Description: N6-acetyllysine; by KAT2A and KAT2B
Type: modified residue
End: 98
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UniProt Feature
UniProt Feature
Begin: 101
Description: N6-acetyllysine; by KAT2A and KAT2B
Type: modified residue
End: 101
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UniProt Feature
UniProt Feature
Begin: 92
Description: N6-acetyllysine; by KAT2A and KAT2B
Type: modified residue
End: 92
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UniProt Feature
UniProt Feature
Begin: 102
Description: N6-acetyllysine; by KAT2A and KAT2B; alternate
Type: modified residue
End: 102
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Allele
Kat2a<em1Smoc> | MGI:7290636
Name: K(lysine) acetyltransferase 2A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6770874 | C57BL/6JSmoc-Kat2a<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Kat2a<tm1Smoc> | MGI:7290637
Name: K(lysine) acetyltransferase 2A; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6354955 | C57BL/6JSmoc-Kat2a<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
22886304 | J:191430
First Author: Carracedo A
Year: 2012
Journal: J Clin Invest
Title: A metabolic prosurvival role for PML in breast cancer.
Volume: 122
Issue: 9
Pages: 3088-100
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Publication
8684459 | -
First Author: Yang XJ
Year: 1996
Journal: Nature
Title: A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.
Volume: 382
Issue: 6589
Pages: 319-24
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Publication
18838386 | -
First Author: Wang YL
Year: 2008
Journal: J Biol Chem
Title: Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
Volume: 283
Issue: 49
Pages: 33808-15
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Protein Domain
IPR016376 | GCN5/PCAF
Type: Family
Description: Eukaryotic GCN5 acetyltransferases influence diverse biological processes by acetylating histones and non-histone proteins and regulating chromatin and gene-specific transcription as part of multiprotein complexes. Vertebrate organisms, express two paralogous GCN5-like acetyltransferases, GCN5 and PCAF (also known as KAT2A and KAT2B), which is included in this entry []. GCN5/PCAF is a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 [, ].
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Protein
E9Q1F7
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
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Protein
F6ZCH1
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Protein
F6SIC5
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
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Publication
9224714 | -
First Author: Grant PA
Year: 1997
Journal: Genes Dev
Title: Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.
Volume: 11
Issue: 13
Pages: 1640-50
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Protein Domain
IPR037800 | GCN5
Type: Family
Description: This entry includes histone acetyltransferases GCN5, KAT2A and KAT2B (all of which are included in ). GCN5 acetylates histones H2B, H3 and H4, providing a specific tag for epigenetic transcription activation. GCN5 is a component of the transcription regulatory histone acetylation (HAT) complexes SAGA [], SLIK [], SALSA []and ADA []. Mammals have two paralogues: KAT2A (also known as GCN5) and KAT2B. KAT2A acetylates core histones to provide a specific tag for epigenetic transcription activation, but not nucleosome core particles. It also acetylates proteins such as CEBPB []. KAT2A is a component of the ATAC complex, which has acetyltransferase activity on histones H3 and H4 []. KAT2B (also known as P300/calcium-binding protein (CBP)-associated factor or PCAF) can acetylate the core histones H3 and H4 as well as nucleosome core particles and non-histone proteins such as ACLY [].The transcription regulatory histone acetylation complex Spt-Ada-Gcn5 acetyltransferase (SAGA) is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. SAGA preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B []. SAGA is known as PCAF in vertebrates and PCAF acetylates nucleosomal histone H3 []. The SAGA complex consists of at least TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1, and some of these components are present as two copies. The complex is built up from distinct modules, each of which has a separate function and crosslinks with either other proteins or other modules in the complex [].SLIK (SAGA-like) is a multi-subunit histone acetyltransferase complex that preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B. It is an embellishment of the SAGA complex. The yeast SLIK complex consists of at least TRA1, CHD1, SPT7, CC TAF5, ADA3, SPT20, RTG2, TAF12, TAF6, HFI1, UBP8 (a deubiquitinase), GCN5, ADA2, SPT3, SGF29, TAF10 and TAF9 [, ].The yeast SALSA complex is an altered form of the SAGA complex and consists of at least TRA1, SPT7 (C-terminal truncated form), TAF5, ADA3, SPT20, TAF12, TAF6, HFI1, GCN5, ADA2 and SPT3 [].The ADA complex is a transcription regulatory histone acetylation (HAT) complex. ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B. The complex consists of at least ADA2, ADA3, AHC1, and GCN5. AHC1 is required for the overall structural integrity of the ADA complex [].
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Publication
27760321 | J:240820
First Author: Tzelepis K
Year: 2016
Journal: Cell Rep
Title: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Volume: 17
Issue: 4
Pages: 1193-1205
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Publication
36879797 | J:334984
First Author: Zhang R
Year: 2023
Journal: iScience
Title: Histone malonylation is regulated by SIRT5 and KAT2A.
Volume: 26
Issue: 3
Pages: 106193
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Publication
23932781 | -
First Author: Lin R
Year: 2013
Journal: Mol Cell
Title: Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.
Volume: 51
Issue: 4
Pages: 506-518
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Publication
10026213 | -
First Author: Grant PA
Year: 1999
Journal: J Biol Chem
Title: Expanded lysine acetylation specificity of Gcn5 in native complexes.
Volume: 274
Issue: 9
Pages: 5895-900
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Publication
9885573 | -
First Author: Grant PA
Year: 1998
Journal: Mol Cell
Title: The ATM-related cofactor Tra1 is a component of the purified SAGA complex.
Volume: 2
Issue: 6
Pages: 863-7
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Protein
Q3UVE8
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: true
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Protein
Q3U2D4
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: false
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Protein
Q9JHD1
Organism: Mus musculus/domesticus
Length: 813  
Fragment?: false
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Protein
Q6P3Z8
Organism: Mus musculus/domesticus
Length: 829  
Fragment?: false
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Protein
Q3UD69
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
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Protein
Q3UM02
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
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Protein
B2RR30
Organism: Mus musculus/domesticus
Length: 813  
Fragment?: false
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Publication
12186975 | -
First Author: Sterner DE
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription.
Volume: 99
Issue: 18
Pages: 11622-7
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Publication
15647753 | -
First Author: Pray-Grant MG
Year: 2005
Journal: Nature
Title: Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.
Volume: 433
Issue: 7024
Pages: 434-8
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Publication
12446794 | -
First Author: Pray-Grant MG
Year: 2002
Journal: Mol Cell Biol
Title: The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.
Volume: 22
Issue: 24
Pages: 8774-86
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Publication
25216679 | -
First Author: Han Y
Year: 2014
Journal: EMBO J
Title: Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.
Volume: 33
Issue: 21
Pages: 2534-46
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Publication
9674425 | J:320277
First Author: Ogryzko VV
Year: 1998
Journal: Cell
Title: Histone-like TAFs within the PCAF histone acetylase complex.
Volume: 94
Issue: 1
Pages: 35-44
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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