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Search results 301 to 400 out of 3295 for Kras

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Type Details Score
Publication
29395869 | J:257777
First Author: Sanclemente M
Year: 2018
Journal: Cancer Cell
Title: c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling.
Volume: 33
Issue: 2
Pages: 217-228.e4
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Publication
25363767 | J:265590
First Author: Westcott PM
Year: 2015
Journal: Nature
Title: The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Volume: 517
Issue: 7535
Pages: 489-92
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Publication
31760766 | J:290584
First Author: Asahina K
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras.
Volume: 318
Issue: 2
Pages: G265-G276
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Publication
23102107 | J:349150
 
First Author: Rachagani S
Year: 2012
Journal: J Hematol Oncol
Title: Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy.
Volume: 5
Pages: 68
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Publication
17468755 | J:122397
First Author: Ventura JJ
Year: 2007
Journal: Nat Genet
Title: p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation.
Volume: 39
Issue: 6
Pages: 750-8
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Publication
12957286 | J:86101
First Author: Guerra C
Year: 2003
Journal: Cancer Cell
Title: Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context.
Volume: 4
Issue: 2
Pages: 111-20
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Publication
19117991 | J:143034
First Author: Pearson HB
Year: 2009
Journal: Cancer Res
Title: K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse.
Volume: 69
Issue: 1
Pages: 94-101
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Publication
29615514 | J:261818
First Author: Orozco CA
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.
Volume: 115
Issue: 16
Pages: E3769-E3778
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Publication
16959882 | J:113749
First Author: Sansom OJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo.
Volume: 103
Issue: 38
Pages: 14122-7
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Publication
23610450 | J:197036
First Author: Ittmann M
Year: 2013
Journal: Cancer Res
Title: Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
Volume: 73
Issue: 9
Pages: 2718-36
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Publication
38574733 | J:348744
First Author: Chang Y
Year: 2024
Journal: Dev Cell
Title: The UBE2F-CRL5(ASB11)-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells.
Volume: 59
Issue: 10
Pages: 1317-1332.e5
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Publication
27058937 | J:235193
First Author: Westphalen CB
Year: 2016
Journal: Cell Stem Cell
Title: Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.
Volume: 18
Issue: 4
Pages: 441-55
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Publication
32234521 | J:336882
First Author: Ruscetti M
Year: 2020
Journal: Cell
Title: Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Volume: 181
Issue: 2
Pages: 424-441.e21
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Publication
31940491 | J:287255
First Author: Blagih J
Year: 2020
Journal: Cell Rep
Title: Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.
Volume: 30
Issue: 2
Pages: 481-496.e6
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Publication
34877497 | J:318004
First Author: Zheng B
Year: 2021
Journal: iScience
Title: A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia.
Volume: 24
Issue: 12
Pages: 103440
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Publication
24444711 | J:212507
First Author: Zhu Z
Year: 2014
Journal: Cancer Discov
Title: Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.
Volume: 4
Issue: 4
Pages: 452-65
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20621056 | J:162238
First Author: Curtis SJ
Year: 2010
Journal: Cell Stem Cell
Title: Primary tumor genotype is an important determinant in identification of lung cancer propagating cells.
Volume: 7
Issue: 1
Pages: 127-33
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34555356 | J:315699
First Author: Sengupta D
Year: 2021
Journal: Mol Cell
Title: NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis.
Volume: 81
Issue: 21
Pages: 4481-4492.e9
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21398220 | J:173832
First Author: Chan G
Year: 2011
Journal: Blood
Title: Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Volume: 117
Issue: 16
Pages: 4253-61
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Publication
19147554 | J:143713
First Author: Seeley ES
Year: 2009
Journal: Cancer Res
Title: Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia.
Volume: 69
Issue: 2
Pages: 422-30
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33521594 | J:306832
First Author: Fleming Martinez AK
Year: 2021
Journal: iScience
Title: Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells.
Volume: 24
Issue: 1
Pages: 102019
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Publication
28514653 | J:254344
First Author: Liou GY
Year: 2017
Journal: Cell Rep
Title: The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis.
Volume: 19
Issue: 7
Pages: 1322-1333
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Publication
28069799 | J:238407
First Author: Rajurkar M
Year: 2017
Journal: Cancer Res
Title: IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis.
Volume: 77
Issue: 2
Pages: 320-329
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Publication
25698580 | J:221790
 
First Author: Liou GY
Year: 2015
Journal: Nat Commun
Title: Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia.
Volume: 6
Pages: 6200
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21984975 | J:185636
First Author: Ying H
Year: 2011
Journal: Cancer Discov
Title: PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.
Volume: 1
Issue: 2
Pages: 158-69
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17785207 | J:124969
First Author: Siveke JT
Year: 2007
Journal: Cancer Cell
Title: Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN.
Volume: 12
Issue: 3
Pages: 266-79
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Publication
25405615 | J:225302
First Author: Wang YJ
Year: 2014
Journal: PLoS One
Title: Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.
Volume: 9
Issue: 11
Pages: e113127
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Publication
22561987 | J:220425
First Author: Ale A
Year: 2012
Journal: Nat Methods
Title: FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography.
Volume: 9
Issue: 6
Pages: 615-20
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Publication
18566322 | J:138720
First Author: Slape C
Year: 2008
Journal: Blood
Title: Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Volume: 112
Issue: 5
Pages: 2017-9
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Publication
7894154 | J:22173
First Author: Devereux TR
Year: 1994
Journal: Mamm Genome
Title: Assignment of a locus for mouse lung tumor susceptibility to proximal chromosome 19.
Volume: 5
Issue: 12
Pages: 749-55
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33045063 | J:306126
 
First Author: Fedele C
Year: 2021
Journal: J Exp Med
Title: SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling.
Volume: 218
Issue: 1
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20708155 | J:163673
First Author: Bennecke M
Year: 2010
Journal: Cancer Cell
Title: Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis.
Volume: 18
Issue: 2
Pages: 135-46
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25437878 | J:220039
First Author: Pershing NL
Year: 2015
Journal: J Clin Invest
Title: Rare codons capacitate Kras-driven de novo tumorigenesis.
Volume: 125
Issue: 1
Pages: 222-33
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27637077 | J:273975
First Author: Song HY
Year: 2016
Journal: Oncotarget
Title: SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status.
Volume: 7
Issue: 49
Pages: 80336-80349
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29195074 | J:251862
First Author: Kortlever RM
Year: 2017
Journal: Cell
Title: Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.
Volume: 171
Issue: 6
Pages: 1301-1315.e14
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24998913 | J:215649
First Author: Lee JV
Year: 2014
Journal: Cell Metab
Title: Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation.
Volume: 20
Issue: 2
Pages: 306-319
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32540961 | J:296294
First Author: Li Y
Year: 2020
Journal: Cancer Res
Title: HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma.
Volume: 80
Issue: 16
Pages: 3265-3278
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Publication
30967626 | J:278171
First Author: Babicky ML
Year: 2019
Journal: Oncogene
Title: MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages.
Volume: 38
Issue: 28
Pages: 5599-5611
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21242978 | J:173715
First Author: Shields DJ
Year: 2011
Journal: Oncogene
Title: Oncogenic Ras/Src cooperativity in pancreatic neoplasia.
Volume: 30
Issue: 18
Pages: 2123-34
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Publication
29134640 | J:248092
     
First Author: Unver N
Year: 2017
Journal: Int J Cancer
Title: Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol.
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Publication
37695315 | J:344729
First Author: Zhang R
Year: 2023
Journal: Cancer Res
Title: Oncogenic KRASG12D Reprograms Lipid Metabolism by Upregulating SLC25A1 to Drive Pancreatic Tumorigenesis.
Volume: 83
Issue: 22
Pages: 3739-3752
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Publication
34216687 | J:310246
 
First Author: Meeusen B
Year: 2021
Journal: Cancer Lett
Title: PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition.
Volume: 520
Pages: 57-67
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Publication
25250570 | J:217621
First Author: Garcia MN
Year: 2014
Journal: J Clin Invest
Title: IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.
Volume: 124
Issue: 11
Pages: 4709-22
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Publication
34635780 | J:314697
First Author: Jang JH
Year: 2021
Journal: Exp Mol Med
Title: Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation.
Volume: 53
Issue: 10
Pages: 1559-1568
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Publication
26967383 | J:314296
First Author: Wang YA
Year: 2016
Journal: Oncotarget
Title: Nitrilase 1 modulates lung tumor progression in vitro and in vivo.
Volume: 7
Issue: 16
Pages: 21381-92
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Publication
29764837 | J:318887
First Author: Khosravi N
Year: 2018
Journal: Cancer Immunol Res
Title: IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties.
Volume: 6
Issue: 7
Pages: 788-797
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Publication
27415425 | J:317881
 
First Author: Loncle C
Year: 2016
Journal: Cell Death Dis
Title: The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation.
Volume: 7
Pages: e2295
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Publication
23935526 | J:200592
First Author: Méniel V
Year: 2013
Journal: PLoS Genet
Title: Cited1 deficiency suppresses intestinal tumorigenesis.
Volume: 9
Issue: 8
Pages: e1003638
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22228755 | J:180576
First Author: Lee CL
Year: 2012
Journal: Dis Model Mech
Title: Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice.
Volume: 5
Issue: 3
Pages: 397-402
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25971796 | J:233465
First Author: García-Beccaria M
Year: 2015
Journal: EMBO Mol Med
Title: Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage.
Volume: 7
Issue: 7
Pages: 930-49
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Publication
24889936 | J:214851
First Author: Martínez-Bosch N
Year: 2014
Journal: J Pathol
Title: Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer.
Volume: 234
Issue: 2
Pages: 214-27
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29351990 | J:258287
First Author: Djurec M
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.
Volume: 115
Issue: 6
Pages: E1147-E1156
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29134654 | J:250840
First Author: Jefferies MT
Year: 2017
Journal: J Pathol
Title: PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
Volume: 243
Issue: 4
Pages: 442-456
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Publication
30905761 | J:274207
First Author: Liao W
Year: 2019
Journal: Cancer Cell
Title: KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer.
Volume: 35
Issue: 4
Pages: 559-572.e7
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29196603 | J:258374
First Author: Hsu SC
Year: 2018
Journal: J Biol Chem
Title: Effects of chondroitin sulfate proteoglycan 4 (NG2/CSPG4) on soft-tissue sarcoma growth depend on tumor developmental stage.
Volume: 293
Issue: 7
Pages: 2466-2475
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25596178 | J:270271
First Author: Martinelli P
Year: 2016
Journal: Gut
Title: The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.
Volume: 65
Issue: 3
Pages: 476-86
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25193384 | J:216687
First Author: Martinengo C
Year: 2014
Journal: Cancer Res
Title: ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.
Volume: 74
Issue: 21
Pages: 6094-106
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26005835 | J:299352
First Author: Depeille P
Year: 2015
Journal: Nat Cell Biol
Title: RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
Volume: 17
Issue: 6
Pages: 804-15
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18372904 | J:132357
First Author: Haigis KM
Year: 2008
Journal: Nat Genet
Title: Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Volume: 40
Issue: 5
Pages: 600-8
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31048544 | J:289183
First Author: Wang L
Year: 2019
Journal: Genes Dev
Title: ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.
Volume: 33
Issue: 11-12
Pages: 641-655
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20023657 | J:208979
First Author: Zhou Y
Year: 2010
Journal: Nat Biotechnol
Title: Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas.
Volume: 28
Issue: 1
Pages: 71-8
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29802314 | J:262978
First Author: Shibata H
Year: 2018
Journal: Nat Commun
Title: In vivo reprogramming drives Kras-induced cancer development.
Volume: 9
Issue: 1
Pages: 2081
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Publication
29141221 | J:255215
First Author: Pierpont TM
Year: 2017
Journal: Cell Rep
Title: Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer.
Volume: 21
Issue: 7
Pages: 1896-1909
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26452271 | J:243686
First Author: Weyandt JD
Year: 2015
Journal: PLoS One
Title: Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.
Volume: 10
Issue: 10
Pages: e0140253
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26151762 | J:225995
   
First Author: Krah NM
Year: 2015
Journal: Elife
Title: The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
Volume: 4
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23715154 | J:203634
First Author: Liu Y
Year: 2013
Journal: Cancer Discov
Title: Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.
Volume: 3
Issue: 8
Pages: 870-9
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22493246 | J:183841
First Author: Rajurkar M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.
Volume: 109
Issue: 17
Pages: E1038-47
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26178787 | J:222466
First Author: Chiou SH
Year: 2015
Journal: Genes Dev
Title: Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
Volume: 29
Issue: 14
Pages: 1576-85
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28220783 | J:243890
 
First Author: Vallejo A
Year: 2017
Journal: Nat Commun
Title: An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.
Volume: 8
Pages: 14294
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37559908 | J:338902
First Author: Guccini I
Year: 2023
Journal: iScience
Title: Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development.
Volume: 26
Issue: 8
Pages: 107368
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23352126 | J:194330
First Author: Shackelford DB
Year: 2013
Journal: Cancer Cell
Title: LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin.
Volume: 23
Issue: 2
Pages: 143-58
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30712876 | J:359967
First Author: Jin C
Year: 2019
Journal: Cell
Title: Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Volume: 176
Issue: 5
Pages: 998-1013.e16
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32499547 | J:291857
First Author: Shankar S
Year: 2020
Journal: Nat Commun
Title: An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development.
Volume: 11
Issue: 1
Pages: 2817
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30467381 | J:349042
First Author: Weng CC
Year: 2019
Journal: Oncogene
Title: Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis.
Volume: 38
Issue: 12
Pages: 2005-2019
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36044839 | J:328133
First Author: Guo B
Year: 2022
Journal: Cell Rep
Title: Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma.
Volume: 40
Issue: 9
Pages: 111253
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30205046 | J:265468
First Author: Kitajima S
Year: 2018
Journal: Cancer Cell
Title: Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS.
Volume: 34
Issue: 3
Pages: 439-452.e6
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Publication
31412251 | J:291038
First Author: Nagdas S
Year: 2019
Journal: Cell Rep
Title: Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth.
Volume: 28
Issue: 7
Pages: 1845-1859.e5
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22264792 | J:180278
First Author: Ling J
Year: 2012
Journal: Cancer Cell
Title: KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
Volume: 21
Issue: 1
Pages: 105-20
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27546622 | J:236077
First Author: Murakami S
Year: 2017
Journal: Oncogene
Title: Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma.
Volume: 36
Issue: 9
Pages: 1232-1244
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27071537 | J:236891
 
First Author: Castellano E
Year: 2016
Journal: Nat Commun
Title: RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression.
Volume: 7
Pages: 11245
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34085047 | J:309100
First Author: Arriaga JM
Year: 2020
Journal: Nat Cancer
Title: A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance.
Volume: 1
Issue: 11
Pages: 1082-1096
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23201164 | J:194378
First Author: Kopp JL
Year: 2012
Journal: Cancer Cell
Title: Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma.
Volume: 22
Issue: 6
Pages: 737-50
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17349581 | J:119990
First Author: Izeradjene K
Year: 2007
Journal: Cancer Cell
Title: Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas.
Volume: 11
Issue: 3
Pages: 229-43
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Publication
30014851 | J:309355
   
First Author: Livshits G
Year: 2018
Journal: Elife
Title: Arid1a restrains Kras-dependent changes in acinar cell identity.
Volume: 7
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Publication
23980075 | J:316965
First Author: Lashinger LM
Year: 2013
Journal: Cancer Prev Res (Phila)
Title: Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I.
Volume: 6
Issue: 10
Pages: 1046-55
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