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Search results 301 to 378 out of 378 for Lgr4

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Type Details Score
Publication
First Author: Saponara E
Year: 2023
Journal: Am J Pathol
Title: Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.
Volume: 193
Issue: 2
Pages: 161-181
Publication
First Author: Du B
Year: 2013
Journal: J Biol Chem
Title: Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression.
Volume: 288
Issue: 21
Pages: 15131-41
Publication
First Author: Wang Z
Year: 2010
Journal: FEBS Lett
Title: GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation.
Volume: 584
Issue: 18
Pages: 4057-62
Publication
First Author: Mustata RC
Year: 2013
Journal: Cell Rep
Title: Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium.
Volume: 5
Issue: 2
Pages: 421-32
Publication
First Author: Zhou B
Year: 2020
Journal: Nat Immunol
Title: The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic-epigenetic reprogramming and resolves inflammatory injury.
Volume: 21
Issue: 11
Pages: 1430-1443
Publication  
First Author: Jin YR
Year: 2020
Journal: Front Cell Dev Biol
Title: Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice.
Volume: 8
Pages: 264
Publication
First Author: Kawasaki M
Year: 2014
Journal: Dev Dyn
Title: R-spondins/Lgrs expression in tooth development.
Volume: 243
Issue: 6
Pages: 844-51
Publication
First Author: Caruso M
Year: 2015
Journal: PLoS One
Title: R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis.
Volume: 10
Issue: 4
Pages: e0124213
Publication
First Author: Snippert HJ
Year: 2010
Journal: Science
Title: Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.
Volume: 327
Issue: 5971
Pages: 1385-9
Publication
First Author: Szenker-Ravi E
Year: 2018
Journal: Nature
Title: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Volume: 557
Issue: 7706
Pages: 564-569
Publication
First Author: Song H
Year: 2008
Journal: J Biol Chem
Title: Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.
Volume: 283
Issue: 52
Pages: 36687-97
Publication
First Author: Reinholdt LG
Year: 2006
Journal: Mech Dev
Title: The mouse gcd2 mutation causes primordial germ cell depletion.
Volume: 123
Issue: 7
Pages: 559-69
Publication
First Author: Gyllborg D
Year: 2018
Journal: Stem Cell Reports
Title: The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.
Volume: 11
Issue: 3
Pages: 651-664
Publication
First Author: Toivanen R
Year: 2017
Journal: Development
Title: Prostate organogenesis: tissue induction, hormonal regulation and cell type specification.
Volume: 144
Issue: 8
Pages: 1382-1398
Publication
First Author: Leighton PA
Year: 2001
Journal: Nature
Title: Defining brain wiring patterns and mechanisms through gene trapping in mice.
Volume: 410
Issue: 6825
Pages: 174-9
Publication
First Author: Luo J
Year: 2009
Journal: Development
Title: Regulation of bone formation and remodeling by G-protein-coupled receptor 48.
Volume: 136
Issue: 16
Pages: 2747-56
Publication
First Author: Voutilainen M
Year: 2015
Journal: PLoS Genet
Title: Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway.
Volume: 11
Issue: 11
Pages: e1005676
Publication
First Author: Rastetter RH
Year: 2014
Journal: Dev Biol
Title: Marker genes identify three somatic cell types in the fetal mouse ovary.
Volume: 394
Issue: 2
Pages: 242-52
Publication
First Author: Fernandez Vallone V
Year: 2020
Journal: EMBO Rep
Title: LGR5 controls extracellular matrix production by stem cells in the developing intestine.
Volume: 21
Issue: 7
Pages: e49224
Publication
First Author: Favor J
Year: 2009
Journal: Genetics
Title: Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes.
Volume: 182
Issue: 4
Pages: 1077-88
Publication
First Author: Planas-Paz L
Year: 2016
Journal: Nat Cell Biol
Title: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.
Volume: 18
Issue: 5
Pages: 467-79
Publication
First Author: Kang HM
Year: 2016
Journal: Cell Rep
Title: Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice.
Volume: 14
Issue: 4
Pages: 861-871
Publication    
First Author: Vidal VP
Year: 2020
Journal: Elife
Title: R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors.
Volume: 9
Publication
First Author: Silvestri C
Year: 2008
Journal: Dev Cell
Title: Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development.
Volume: 14
Issue: 3
Pages: 411-23
Publication
First Author: Seishima R
Year: 2019
Journal: Nat Commun
Title: Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.
Volume: 10
Issue: 1
Pages: 5378
Publication
First Author: Weng J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.
Volume: 105
Issue: 16
Pages: 6081-6
Publication  
First Author: Brommage R
Year: 2014
Journal: Bone Res
Title: High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.
Volume: 2
Pages: 14034
Publication
First Author: Sigal M
Year: 2017
Journal: Nature
Title: Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Volume: 548
Issue: 7668
Pages: 451-455
Publication      
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
Publication    
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Styrkarsdottir U
Year: 2013
Journal: Nature
Title: Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits.
Volume: 497
Issue: 7450
Pages: 517-20
Publication  
First Author: Yue Z
Year: 2022
Journal: J Clin Invest
Title: RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis.
Volume: 132
Issue: 2
GXD Expression  
Probe: MGI:7596164
Assay Type: RNA in situ
Annotation Date: 2024-02-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3262722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7596266
Age: embryonic day 14.5
Note: Strong expression co-localized with Lgr4 in apical ectodermal ridge.
Specimen Label: 2h Lgr4/Rspo2 (upper)
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7596164
Assay Type: RNA in situ
Annotation Date: 2024-02-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3262722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7596266
Age: embryonic day 14.5
Note: Strong expression co-localized with Lgr4 in apical ectodermal ridge.
Specimen Label: 2h Lgr4/Rspo2 (lower)
Detected: true
Specimen Num: 2
Publication
First Author: Deng C
Year: 2013
Journal: J Cell Sci
Title: Multi-functional norrin is a ligand for the LGR4 receptor.
Volume: 126
Issue: Pt 9
Pages: 2060-8
Publication    
First Author: Geng A
Year: 2020
Journal: Elife
Title: A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.
Volume: 9
Publication
First Author: de Oliveira V
Year: 2019
Journal: FASEB J
Title: Uterine Gαq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse.
Volume: 33
Issue: 8
Pages: 9374-9387
Publication
First Author: Park S
Year: 2018
Journal: J Biol Chem
Title: Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
Volume: 293
Issue: 25
Pages: 9759-9769
Publication
First Author: Hsu SY
Year: 2000
Journal: Mol Endocrinol
Title: The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7.
Volume: 14
Issue: 8
Pages: 1257-71
Publication
First Author: Carmon KS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.
Volume: 111
Issue: 13
Pages: E1221-9
Publication
First Author: Liu SL
Year: 2019
Journal: Biochem Biophys Res Commun
Title: LGR6 promotes osteogenesis by activating the Wnt/β-catenin signaling pathway.
Volume: 519
Issue: 1
Pages: 1-7
Publication
First Author: Wizenty J
Year: 2022
Journal: EMBO J
Title: Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Volume: 41
Issue: 13
Pages: e109996
Publication
First Author: Hsu SY
Year: 1998
Journal: Mol Endocrinol
Title: Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.
Volume: 12
Issue: 12
Pages: 1830-45