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Search results 301 to 317 out of 317 for Ltn1

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0.017s

Type

Details

Score

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

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Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

23319619 | -

First Author:	Lyumkis D
Year:	2013
Journal:	Proc Natl Acad Sci U S A
Title:	Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase.
Volume:	110
Issue:	5
Pages:	1702-7

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Publication

32934225 | J:296528

First Author:	Martin PB
Year:	2020
Journal:	Nat Commun
Title:	NEMF mutations that impair ribosome-associated quality control are associated with neuromuscular disease.
Volume:	11
Issue:	1
Pages:	4625

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Publication

8575820 | J:35330

First Author:	Maeda YY
Year:	1996
Journal:	Immunogenetics
Title:	Two genes controlling acute phase responses by the antitumor polysacch aride, lentinan.
Volume:	43
Issue:	4
Pages:	215-9

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Publication

25349383 | -

First Author:	Lyumkis D
Year:	2014
Journal:	Proc Natl Acad Sci U S A
Title:	Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex.
Volume:	111
Issue:	45
Pages:	15981-6

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Publication

20835226 | -

First Author:	Bengtson MH
Year:	2010
Journal:	Nature
Title:	Role of a ribosome-associated E3 ubiquitin ligase in protein quality control.
Volume:	467
Issue:	7314
Pages:	470-3

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Publication

25132172 | -

First Author:	Shao S
Year:	2014
Journal:	Mol Cell
Title:	Reconstitution of a minimal ribosome-associated ubiquitination pathway with purified factors.
Volume:	55
Issue:	6
Pages:	880-890

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Protein Domain

IPR039804 | RING-CH-C4HC3_LTN1

Type:

Domain

Description:

Listerin, also known as RING finger protein 160 or zinc finger protein 294, is the mammalian homologue of yeast Ltn1. It is widely expressed in all tissues, but motor and sensory neurons and neuronal processes in the brainstem and spinal cord are primarily affected in the mutant. Listerin is required for embryonic development and plays an important role in neurodegeneration []. It also functions as a critical E3 ligase involving quality control of nonstop proteins [, ]. It mediates ubiquitylation of aberrant proteins that become stalled on ribosomes during translation []. Ltn1 works with several cofactors to form a large ribosomal subunit-associated quality control complex (RQC), which mediates the ubiquitylation and extraction of ribosome-stalled nascent polypeptide chains for proteasomal degradation. It appears to first associate with nascent chain-stalled 60S subunits together with two proteins of unknown function, Tae2 and Rqc1 [].Listerin contains a long stretch of HEAT (Huntingtin, Elongation factor 3, PR65/A subunit of protein phosphatase 2A, and TOR) or ARM (Armadillo) repeats in the N terminus and middle region, and a catalytic RING-CH finger, also known as vRING or RINGv, with an unusual arrangement of zinc-coordinating residues in the C terminus. Its cysteines and histidines are arranged in the sequence as C4HC3-type, rather than the C3H2C3-type in canonical RING-H2 finger [].

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Protein

Q0P617

Organism:	Mus musculus/domesticus
Length:	131
Fragment?:	false

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Protein

Q6A009

Organism:	Mus musculus/domesticus
Length:	1767
Fragment?:	false

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