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Search results 301 to 380 out of 380 for Lyst

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Type Details Score
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Lyst<bg-14J> | MGI:2672943
 
Name: lysosomal trafficking regulator; beige 14 Jackson
Allele Type: Chemically induced (ENU)
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Strain
MGI:2672860 | C3Fe;B6-Lyst<bg-14J>
Attribute String: chemically induced mutation, mutant stock
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Genotype
Genotype
Symbol: Lyst/Lyst
Background: C3Fe;B6-Lyst
Zygosity: hm
Has Mutant Allele: true
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Allele
Lyst<em1Smoc> | MGI:7290917
Name: lysosomal trafficking regulator; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
28348241 | J:242147
First Author: Kruusvee V
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.
Volume: 114
Issue: 16
Pages: E3243-E3250
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Strain
MGI:6475732 | C57BL/6JSmoc-Lyst<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
30463906 | J:272570
First Author: Koerner MV
Year: 2018
Journal: Genes Dev
Title: Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.
Volume: 32
Issue: 23-24
Pages: 1514-1524
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Publication
23770587 | J:204723
First Author: Ebert DH
Year: 2013
Journal: Nature
Title: Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.
Volume: 499
Issue: 7458
Pages: 341-5
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Publication
- | J:289870
     
First Author: Tillotson R
Year: 2020
Journal: bioRxiv
Title: Neuronal non-CG methylation is an essential target for MeCP2 function.
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Allele
Lyst<bg-15J> | MGI:3617811
 
Name: lysosomal trafficking regulator; beige 15 Jackson
Allele Type: Chemically induced (ENU)
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Strain
MGI:3617813 | C57BL/6J-Lyst<bg-15J>/Llp
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Lyst/Lyst
Background: involves: C3H * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
33561390 | J:309631
First Author: Tillotson R
Year: 2021
Journal: Mol Cell
Title: Neuronal non-CG methylation is an essential target for MeCP2 function.
Volume: 81
Issue: 6
Pages: 1260-1275.e12
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Allele
Lyst<bg-Nga> | MGI:6378151
Name: lysosomal trafficking regulator; beige Nagoya
Allele Type: Spontaneous
Attribute String: Not Specified
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HT Experiment
E-GEOD-16994 | Microarray analysis of iris gene expression in mice with mutations relevant to glaucoma
Series Id: GSE16994
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
11102458 | J:66143
First Author: Wang X
Year: 2000
Journal: J Neurosci
Title: Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic.
Volume: 20
Issue: 23
Pages: 8551-65
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Allele
Lyst<bg-3Btlr> | MGI:3826359
 
Name: lysosomal trafficking regulator; beige 3 Bruce Beutler
Allele Type: Chemically induced (ENU)
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Allele
Lyst<bg-8Btlr> | MGI:5789550
Name: lysosomal trafficking regulator; beige 8 Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Lyst<bg-9Btlr> | MGI:5789566
Name: lysosomal trafficking regulator; beige 9 Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:5789639 | C57BL/6J-Lyst<bg-9Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Allele
Lyst<bg-11Btlr> | MGI:6200258
Name: lysosomal trafficking regulator; beige 11 Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200259 | C57BL/6J-Lyst<bg-11Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Strain
MGI:6474560 | B6.Cg-Pbwg1.24<M. m. castaneus> Lyst<bg-Nga>/NgaRbrc
Attribute String: congenic, mutant strain, spontaneous mutation
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Genotype
Genotype
Symbol: Lyst/Lyst
Background: C57BL/6J-Lyst
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyst/Lyst
Background: C57BL/6J-Lyst
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:3826664 | C57BL/6J-Lyst<bg-3Btlr>
Attribute String: coisogenic, chemically induced mutation
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Strain
MGI:5789629 | C57BL/6J-Lyst<bg-8Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Genotype
Genotype
Symbol: Lyst/Lyst
Background: C57BL/6J-Lyst
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyst/Lyst
Background: C57BL/6J-Lyst
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR036372 | BEACH_dom_sf
Type: Homologous_superfamily
Description: BEACH (Beige and Chediak-Higashi) domains, implicated in membrane trafficking, are present in a family of proteins conserved throughout eukaryotes. This group contains human lysosomal trafficking regulator (LYST), LPS-responsive and beige-like anchor (LRBA) and neurobeachin. Disruption of LYST leads to Chediak-Higashi syndrome, characterized by severe immunodeficiency, albinism, poor blood coagulation and neurologic problems. Neurobeachin is a candidate gene linked to autism. LBRA seems to be upregulated in several cancer types. It has been shown that the BEACH domain itself is important for the function of these proteins [, , , , , , , ].The BEACH domain is usually followed by a series of WD repeats.
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Protein Domain
IPR000409 | BEACH_dom
Type: Domain
Description: BEACH (Beige and Chediak-Higashi) domains, implicated in membrane trafficking, are present in a family of proteins conserved throughout eukaryotes. This group contains human lysosomal trafficking regulator (LYST), LPS-responsive and beige-like anchor (LRBA) and neurobeachin. Disruption of LYST leads to Chediak-Higashi syndrome, characterized by severe immunodeficiency, albinism, poor blood coagulation and neurologic problems. Neurobeachin is a candidate gene linked to autism. LBRA seems to be upregulated in several cancer types. It has been shown that the BEACH domain itself is important for the function of these proteins [, , , , , , , ].The BEACH domain is usually followed by a series of WD repeats.
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Publication
15342963 | J:94931
First Author: Chen GY
Year: 2004
Journal: Cell Struct Funct
Title: Expression profile of mouse BWF1, a protein with a BEACH domain, WD40 domain and FYVE domain.
Volume: 29
Issue: 2
Pages: 35-42
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Protein
F6U6E8
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: true
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Publication
12535270 | -
First Author: De Lozanne A
Year: 2003
Journal: Traffic
Title: The role of BEACH proteins in Dictyostelium.
Volume: 4
Issue: 1
Pages: 6-12
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Publication
15193433 | -
First Author: Chen J
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Identification and characterization of NBEAL1, a novel human neurobeachin-like 1 protein gene from fetal brain, which is up regulated in glioma.
Volume: 125
Issue: 1-2
Pages: 147-55
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Publication
17079274 | J:119673
First Author: Khodosh R
Year: 2006
Journal: Development
Title: Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events.
Volume: 133
Issue: 23
Pages: 4655-65
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Publication
15086784 | -
First Author: Wu WI
Year: 2004
Journal: Traffic
Title: Structure-function analysis of the BEACH protein LvsA.
Volume: 5
Issue: 5
Pages: 346-55
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Publication
12125812 | -
First Author: Ward DM
Year: 2002
Journal: Curr Mol Med
Title: Chediak-Higashi syndrome: a clinical and molecular view of a rare lysosomal storage disorder.
Volume: 2
Issue: 5
Pages: 469-77
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Publication
12210762 | -
First Author: Wang N
Year: 2002
Journal: J Cell Biochem
Title: BEACH family of proteins: phylogenetic and functional analysis of six Dictyostelium BEACH proteins.
Volume: 86
Issue: 3
Pages: 561-70
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Publication
20739468 | J:171565
First Author: Trantow CM
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Microarray analysis of iris gene expression in mice with mutations influencing pigmentation.
Volume: 52
Issue: 1
Pages: 237-48
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Publication
9300652 | J:42615
First Author: Jackson IJ
Year: 1997
Journal: Hum Mol Genet
Title: Homologous pigmentation mutations in human, mouse and other model organisms.
Volume: 6
Issue: 10
Pages: 1613-24
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Publication
15173323 | J:90848
First Author: Fujita H
Year: 2004
Journal: J Cell Sci
Title: Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.
Volume: 117
Issue: Pt 14
Pages: 2997-3009
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Protein
Q8CBR4
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: true
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Protein
O35242
Organism: Mus musculus/domesticus
Length: 920  
Fragment?: false
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Protein
Q5ND34
Organism: Mus musculus/domesticus
Length: 1934  
Fragment?: false
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Protein
Q8BSM6
Organism: Mus musculus/domesticus
Length: 758  
Fragment?: false
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Protein
Q8C7M6
Organism: Mus musculus/domesticus
Length: 764  
Fragment?: false
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Protein
A0A5F8MPY6
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: true
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Protein
Q8BRX5
Organism: Mus musculus/domesticus
Length: 550  
Fragment?: false
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Protein
E9PV03
Organism: Mus musculus/domesticus
Length: 1179  
Fragment?: true
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Protein
Q7TMN9
Organism: Mus musculus/domesticus
Length: 707  
Fragment?: true
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Protein
K4DI77
Organism: Mus musculus/domesticus
Length: 1934  
Fragment?: true
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Protein
F6ZZB1
Organism: Mus musculus/domesticus
Length: 1073  
Fragment?: true
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Protein
A0A0A6YXX3
Organism: Mus musculus/domesticus
Length: 2577  
Fragment?: false
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Protein
Q9EPN1
Organism: Mus musculus/domesticus
Length: 2936  
Fragment?: false
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Protein
E9Q2M9
Organism: Mus musculus/domesticus
Length: 3183  
Fragment?: false
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Protein
E9PV60
Organism: Mus musculus/domesticus
Length: 3024  
Fragment?: false
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Protein
F6VTL9
Organism: Mus musculus/domesticus
Length: 2032  
Fragment?: true
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Protein
Q3U2N8
Organism: Mus musculus/domesticus
Length: 809  
Fragment?: true
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Protein
E9PYP2
Organism: Mus musculus/domesticus
Length: 2688  
Fragment?: false
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Protein
Q9ESE1
Organism: Mus musculus/domesticus
Length: 2856  
Fragment?: false
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Protein
Q6ZQA0
Organism: Mus musculus/domesticus
Length: 2742  
Fragment?: false
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Protein
B2RXS1
Organism: Mus musculus/domesticus
Length: 2750  
Fragment?: false
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Protein
E9Q3Y4
Organism: Mus musculus/domesticus
Length: 2854  
Fragment?: false
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Protein
A0A0A6YXL6
Organism: Mus musculus/domesticus
Length: 2790  
Fragment?: false
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Protein
E9Q9L6
Organism: Mus musculus/domesticus
Length: 2750  
Fragment?: false
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Protein
A0A0G2JFQ4
Organism: Mus musculus/domesticus
Length: 2716  
Fragment?: false
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Protein
B7ZWL5
Organism: Mus musculus/domesticus
Length: 2723  
Fragment?: false
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Protein
Q8CHB9
Organism: Mus musculus/domesticus
Length: 646  
Fragment?: true
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Protein
Q6VNB8
Organism: Mus musculus/domesticus
Length: 3508  
Fragment?: false
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Protein
A0A1D5RLV7
Organism: Mus musculus/domesticus
Length: 3512  
Fragment?: false
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Protein
G3UYW1
Organism: Mus musculus/domesticus
Length: 3526  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom