Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 352 out of 352 for Mafk

<< First < Previous | Next > Last >>

0.019s

Type

Details

Score

Publication

15665000 | -

First Author:	Zhao L
Year:	2005
Journal:	J Biol Chem
Title:	The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription.
Volume:	280
Issue:	12
Pages:	11887-94

•

Publication

15923615 | J:99126

First Author:	Zhang C
Year:	2005
Journal:	Mol Cell Biol
Title:	MafA is a key regulator of glucose-stimulated insulin secretion.
Volume:	25
Issue:	12
Pages:	4969-76

•

Publication

11583919 | -

First Author:	Shimokawa N
Year:	2001
Journal:	Cell Signal
Title:	MafG-2 is a novel Maf protein that is expressed by stimulation of extracellular H(+).
Volume:	13
Issue:	11
Pages:	835-9

•

Publication

19168627 | -

First Author:	Schembri F
Year:	2009
Journal:	Proc Natl Acad Sci U S A
Title:	MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.
Volume:	106
Issue:	7
Pages:	2319-24

•

Publication

9525857 | -

First Author:	Ogino H
Year:	1998
Journal:	Science
Title:	Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf.
Volume:	280
Issue:	5360
Pages:	115-8

•

Publication

12011435 | -

First Author:	Olbrot M
Year:	2002
Journal:	Proc Natl Acad Sci U S A
Title:	Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.
Volume:	99
Issue:	10
Pages:	6737-42

•

Publication

9674710 | -

First Author:	Benkhelifa S
Year:	1998
Journal:	Oncogene
Title:	mafA, a novel member of the maf proto-oncogene family, displays developmental regulation and mitogenic capacity in avian neuroretina cells.
Volume:	17
Issue:	2
Pages:	247-54

•

Publication

20627934 | J:169626

First Author:	Artner I
Year:	2010
Journal:	Diabetes
Title:	MafA and MafB regulate genes critical to beta-cells in a unique temporal manner.
Volume:	59
Issue:	10
Pages:	2530-9

•

Publication

21719305 | -

First Author:	Hang Y
Year:	2011
Journal:	Trends Endocrinol Metab
Title:	MafA and MafB activity in pancreatic β cells.
Volume:	22
Issue:	9
Pages:	364-73

•

Publication

12217315 | J:78764

First Author:	Sadl V
Year:	2002
Journal:	Dev Biol
Title:	The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells.
Volume:	249
Issue:	1
Pages:	16-29

•

Publication

19632180 | J:157326

First Author:	Sarrazin S
Year:	2009
Journal:	Cell
Title:	MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells.
Volume:	138
Issue:	2
Pages:	300-13

•

Publication

22387013 | -

First Author:	Zankl A
Year:	2012
Journal:	Am J Hum Genet
Title:	Multicentric carpotarsal osteolysis is caused by mutations clustering in the amino-terminal transcriptional activation domain of MAFB.
Volume:	90
Issue:	3
Pages:	494-501

•

Publication

22445942 | -

First Author:	Jayaram H
Year:	2012
Journal:	Exp Eye Res
Title:	Focus on molecules: neural retina leucine zipper (NRL).
Volume:	104

Pages:	99-100

•

Publication

11694879 | J:78692

First Author:	Mears AJ
Year:	2001
Journal:	Nat Genet
Title:	Nrl is required for rod photoreceptor development.
Volume:	29
Issue:	4
Pages:	447-52

•

Publication

10192380 | -

First Author:	Bessant DA
Year:	1999
Journal:	Nat Genet
Title:	A mutation in NRL is associated with autosomal dominant retinitis pigmentosa.
Volume:	21
Issue:	4
Pages:	355-6

•

Publication

22334370 | -

First Author:	Neveling K
Year:	2012
Journal:	Hum Mutat
Title:	Next-generation genetic testing for retinitis pigmentosa.
Volume:	33
Issue:	6
Pages:	963-72

•

Publication

15591106 | -

First Author:	Nishiguchi KM
Year:	2004
Journal:	Proc Natl Acad Sci U S A
Title:	Recessive NRL mutations in patients with clumped pigmentary retinal degeneration and relative preservation of blue cone function.
Volume:	101
Issue:	51
Pages:	17819-24

•

Protein Domain

IPR028571 | MafB

Type:

Family

Description:

Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors. The Maf family is divided into two subclasses, large Mafs (c-maf, mafB, and mafA/L-maf, nrl) and small Mafs (MafF, MafK and MafG). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. In contrast to the small Mafs, the large Maf proteins contain a transactivator domain in their amino terminus.MafB plays critical roles in a variety of cellular differentiation processes, including in kidney podocytes [], macrophages [, ], and pancreatic islet alpha and beta-cells, which are responsible for the production of the hormones glucagon and insulin respectively. MafB is also expressed in alpha-cells in adult pancreas and is important for their function [, , , ].Mutations in Maf gene cause multicentric carpotarsal osteolysis syndrome (MCTO), which is a rare skeletal disorder, usually presenting in early childhood with a clinical picture mimicking juvenile rheumatoid arthritis [].

•

Protein Domain

IPR028575 | Nrl

Type:

Family

Description:

Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors. The Maf family is divided into two subclasses, large Mafs (c-maf, mafB, and mafA/L-maf, Nrl) and small Mafs (MafF, MafK and MafG). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. In contrast to the small Mafs, the large Maf proteins contain a transactivator domain in their amino terminus.Neural retina-specific leucine zipper protein (Nrl) is a member of the Maf family of transcription factors that regulates the expression of rod-specific genes, including rhodopsin [, , ]. Mutations in Nrl cause retinitis pigmentosa 27 (RP27), which is a retinal dystrophy belonging to the group of pigmentary retinopathies [, ], and retinal degeneration autosomal recessive clumped pigment type (RDCP), which is a retinopathy characterised by night blindness since early childhood, consistent with a severe reduction in rod function [].

•

Protein Domain

IPR028562 | MafA

Type:

Family

Description:

Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors. The Maf family is divided into two subclasses, large Mafs (c-maf, mafB, and mafA/L-maf, nrl) and small Mafs (MafF, MafK and MafG). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. In contrast to the small Mafs, the large Maf proteins contain a transactivator domain in their amino terminus []. The small Maf proteins might contribute to oncogenic processes by participating in antioxidant responses, while large Maf proteins have been directly implicated in carcinogenesis []. This entry represents MafA. MafA plays a critical role in the regulation of crystalline genes and lens development [, ]. It also binds the insulin enhancer element RIPE3b and regulates the insulin gene transcription [, , ].

•

Protein Domain

IPR028551 | MafG

Type:

Family

Description:

Maf transcription factors form a distinct family of the basic leucine zipper (bZip) transcription factors []. The Maf family is divided into two subclasses, large Mafs and small Mafs (MafF, MafK []and MafG []). Both subclasses contain leucine-zipper motifs, which allow homodimerisation as well as heterodimerisation with a variety of other bZip proteins. Small Mafs can act as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can then displace active dimers. Small Mafs lack a transactivator domain, but they can also serve as transcriptional activators by dimerising with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. This entry represents MafG. The p45/MafG heterodimer plays a role in the regulation of erythropoiesis []and may be involved in signal transduction of extracellular H+ []. MAFG is up-regulated in smokers [].

•

Publication

10037736 | J:53336

First Author:	Kobayashi A
Year:	1999
Journal:	J Biol Chem
Title:	Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.
Volume:	274
Issue:	10
Pages:	6443-52

•

Publication

24202329 | J:206564

First Author:	Chiou SS
Year:	2013
Journal:	Cancers (Basel)
Title:	Control of Oxidative Stress and Generation of Induced Pluripotent Stem Cell-like Cells by Jun Dimerization Protein 2.
Volume:	5
Issue:	3
Pages:	959-84

•

Publication

12356737 | J:100802

First Author:	Sun J
Year:	2002
Journal:	EMBO J
Title:	Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene.
Volume:	21
Issue:	19
Pages:	5216-24

•

Publication

27030212 | J:318621

First Author:	Matsumoto M
Year:	2016
Journal:	Genes Cells
Title:	Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1-Pparg pathway in adipogenesis.
Volume:	21
Issue:	6
Pages:	553-67

•

Publication

27427974 | J:317872

First Author:	Pajares M
Year:	2016
Journal:	Autophagy
Title:	Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.
Volume:	12
Issue:	10
Pages:	1902-1916

•

Publication

8910469 | J:36621

First Author:	Ohtsu H
Year:	1996
Journal:	J Biol Chem
Title:	Histidine decarboxylase expression in mouse mast cell line P815 is induced by mouse peritoneal cavity incubation.
Volume:	271
Issue:	45
Pages:	28439-44

•

Publication

9478996 | J:46244

First Author:	Nagai T
Year:	1998
Journal:	J Biol Chem
Title:	Regulation of NF-E2 activity in erythroleukemia cell differentiation.
Volume:	273
Issue:	9
Pages:	5358-65

•

Publication

25763640 | J:227449

First Author:	Nomoto H
Year:	2015
Journal:	Endocrinology
Title:	Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion.
Volume:	156
Issue:	10
Pages:	3570-80

•

Publication

23936317 | -

First Author:	Chen Z
Year:	2013
Journal:	PLoS One
Title:	Nuclear translocation of B-cell-specific transcription factor, BACH2, modulates ROS mediated cytotoxic responses in mantle cell lymphoma.
Volume:	8
Issue:	8
Pages:	e69126

•

Publication

23754397 | J:197975

First Author:	Tsukumo S
Year:	2013
Journal:	Proc Natl Acad Sci U S A
Title:	Bach2 maintains T cells in a naive state by suppressing effector memory-related genes.
Volume:	110
Issue:	26
Pages:	10735-40

•

Publication

22875853 | -

First Author:	Liang Y
Year:	2012
Journal:	J Biol Chem
Title:	Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis.
Volume:	287
Issue:	40
Pages:	33533-44

•

Protein Domain

IPR043321 | bZIP_BACH

Type:

Domain

Description:

BACH proteins are Cap'n'Collar (CNC) Basic leucine zipper (bZIP) transcription factors that are defined by a conserved 43-amino acid region (called the CNC domain) located N-terminal to the bZIP DNA-binding domain. In addition, they contain a BTB domain (Broad complex-Tramtrack-Bric-a-brac domain, also known as the POZ [poxvirus and zinc finger]domain) that is absent in other CNC proteins. Veterbrates contain two members, BACH1 and BACH2. BACH1 forms heterodimers with small Mafs such as MafK to function as a repressor of heme oxygenase-1 (HO-1) gene (Hmox-1) enhancers []. It has also been implicated as the master regulator of breast cancer bone metastasis []. The BACH1 bZIP transcription factor should not be confused with the protein originally named as BRCA1-Associated C-terminal Helicase1 (BACH1), which has been renamed BRIP1 (BRCA1 Interacting Protein C-terminal Helicase1) and also called FANCJ. BACH2 is a B-cell specific transcription factor that plays a critical role in oxidative stress-mediated apoptosis []. It plays an important role in class switching and somatic hypermutation of immunoglobulin genes [].

•

Publication

24232097 | J:207226

First Author:	Tanigawa S
Year:	2013
Journal:	Cell Death Dis
Title:	Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis.
Volume:	4

Pages:	e921

•

Protein

A0A2I3BQU2

Organism:	Mus musculus/domesticus
Length:	62
Fragment?:	true

•

Publication

7665895 | J:105228

First Author:	Zhumabekov T
Year:	1995
Journal:	J Immunol Methods
Title:	Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice.
Volume:	185
Issue:	1
Pages:	133-40

•

Protein

P97302

Organism:	Mus musculus/domesticus
Length:	739
Fragment?:	false

•

Protein

P97303

Organism:	Mus musculus/domesticus
Length:	839
Fragment?:	false

•

Protein

P54846

Organism:	Mus musculus/domesticus
Length:	237
Fragment?:	false

•

Protein

P54841

Organism:	Mus musculus/domesticus
Length:	323
Fragment?:	false

•

Protein

Q8CF90

Organism:	Mus musculus/domesticus
Length:	359
Fragment?:	false

•

Protein

O54790

Organism:	Mus musculus/domesticus
Length:	162
Fragment?:	false

•

Protein

Q543Y0

Organism:	Mus musculus/domesticus
Length:	237
Fragment?:	false

•

Protein

Q3URL4

Organism:	Mus musculus/domesticus
Length:	739
Fragment?:	false

•

Protein

Q80WG0

Organism:	Mus musculus/domesticus
Length:	240
Fragment?:	true

•

Protein

A0A2I3BPV3

Organism:	Mus musculus/domesticus
Length:	226
Fragment?:	true

•

Protein

Q3US24

Organism:	Mus musculus/domesticus
Length:	739
Fragment?:	false

•

Protein

Q3US63

Organism:	Mus musculus/domesticus
Length:	739
Fragment?:	false

•

Protein

Q8C8Y1

Organism:	Mus musculus/domesticus
Length:	237
Fragment?:	false

•

Protein

Q3V2C2

Organism:	Mus musculus/domesticus
Length:	168
Fragment?:	true

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=300&searchTerm=Mafk

MouseMine

Search our database by keyword

Examples

Search results 301 to 352 out of 352 for Mafk

Categories

Hits by Pathway

Hits by Category

Hits by Strain