Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:6406848 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-04-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750320 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:6406977 |
Age: |
embryonic day 12.5 |
Image: |
2 - E12.5 |
|
Specimen Label: |
2 - E12.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6406848 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-04-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6406977 |
Age: |
embryonic day 16.5 |
Image: |
2 - E16.5 |
|
Specimen Label: |
2 - E16.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6406848 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-04-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750327 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6406977 |
Age: |
postnatal newborn |
Image: |
2 - neonate |
|
Specimen Label: |
2 - neonate |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6406848 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-04-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:6406977 |
Age: |
embryonic day 14.5 |
Image: |
2 - E14.5 |
|
Specimen Label: |
2 - E14.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693145 |
Age: |
postnatal adult |
Image: |
UC Davis_1861900 |
|
Specimen Label: |
UC Davis_1861900 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693145 |
Age: |
postnatal adult |
Image: |
UC Davis_1861901 |
|
Specimen Label: |
UC Davis_1861901 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693145 |
Age: |
postnatal adult |
Image: |
UC Davis_1861902 |
|
Specimen Label: |
UC Davis_1861902 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6693145 |
Age: |
postnatal adult |
Image: |
UC Davis_1861909 |
|
Specimen Label: |
UC Davis_1861909 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stegbauer J |
Year: |
2019 |
Journal: |
J Vasc Surg |
Title: |
Mas receptor deficiency augments angiotensin II-induced atherosclerosis and aortic aneurysm ruptures in hypercholesterolemic male mice. |
Volume: |
70 |
Issue: |
5 |
Pages: |
1658-1668.e1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suski M |
Year: |
2013 |
Journal: |
Biochim Biophys Acta |
Title: |
The influence of angiotensin-(1-7) Mas receptor agonist (AVE 0991) on mitochondrial proteome in kidneys of apoE knockout mice. |
Volume: |
1834 |
Issue: |
12 |
Pages: |
2463-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
von Bohlen und Halbach O |
Year: |
2001 |
Journal: |
Regul Pept |
Title: |
Genetic deletion of angiotensin AT2 receptor leads to increased cell numbers in different brain structures of mice. |
Volume: |
99 |
Issue: |
2-3 |
Pages: |
209-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao X |
Year: |
2022 |
Journal: |
Elife |
Title: |
ACE2 pathway regulates thermogenesis and energy metabolism. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fang C |
Year: |
2013 |
Journal: |
Blood |
Title: |
Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation. |
Volume: |
121 |
Issue: |
15 |
Pages: |
3023-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nozato S |
Year: |
2019 |
Journal: |
Clin Sci (Lond) |
Title: |
Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice. |
Volume: |
133 |
Issue: |
18 |
Pages: |
2005-2018 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2016 |
Journal: |
Neuropharmacology |
Title: |
Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors. |
Volume: |
105 |
|
Pages: |
114-123 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song LN |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism. |
Volume: |
34 |
Issue: |
12 |
Pages: |
16291-16306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Villar AJ |
Year: |
1994 |
Journal: |
Nat Genet |
Title: |
Parental imprinting of the Mas protooncogene in mouse. |
Volume: |
8 |
Issue: |
4 |
Pages: |
373-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dadam FM |
Year: |
2017 |
Journal: |
Mol Cell Endocrinol |
Title: |
Sex chromosome complement involvement in angiotensin receptor sexual dimorphism. |
Volume: |
447 |
|
Pages: |
98-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rooney RJ |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice. |
Volume: |
9 |
Issue: |
4 |
Pages: |
320-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ali Q |
Year: |
2016 |
Journal: |
J Renin Angiotensin Aldosterone Syst |
Title: |
Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin II type 2 receptor/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury. |
Volume: |
17 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Giani JF |
Year: |
2012 |
Journal: |
Growth Horm IGF Res |
Title: |
Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice. |
Volume: |
22 |
Issue: |
6 |
Pages: |
224-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cebra-Thomas JA |
Year: |
1992 |
Journal: |
Genomics |
Title: |
Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting. |
Volume: |
13 |
Issue: |
2 |
Pages: |
444-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Esteban V |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e5406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cuffe JS |
Year: |
2014 |
Journal: |
Placenta |
Title: |
The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. |
Volume: |
35 |
Issue: |
11 |
Pages: |
953-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohshima K |
Year: |
2014 |
Journal: |
Hypertension |
Title: |
Possible role of angiotensin-converting enzyme 2 and activation of angiotensin II type 2 receptor by angiotensin-(1-7) in improvement of vascular remodeling by angiotensin II type 1 receptor blockade. |
Volume: |
63 |
Issue: |
3 |
Pages: |
e53-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muñoz MC |
Year: |
2014 |
Journal: |
J Endocrinol |
Title: |
Downregulation of the ACE2/Ang-(1-7)/Mas axis in transgenic mice overexpressing GH. |
Volume: |
221 |
Issue: |
2 |
Pages: |
215-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castro CH |
Year: |
2005 |
Journal: |
Hypertension |
Title: |
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. |
Volume: |
46 |
Issue: |
4 |
Pages: |
937-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
1999 |
Journal: |
J Neurosci |
Title: |
Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors. |
Volume: |
19 |
Issue: |
12 |
Pages: |
4938-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0128216 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meighan-Mantha RL |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. |
Volume: |
274 |
Issue: |
46 |
Pages: |
33166-76 |
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•
•
•
•
•
|
Publication |
First Author: |
Callera GE |
Year: |
2016 |
Journal: |
Biosci Rep |
Title: |
Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis. |
Volume: |
36 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Himmelbauer H |
Year: |
1994 |
Journal: |
Mamm Genome |
Title: |
High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci. |
Volume: |
5 |
Issue: |
12 |
Pages: |
814-6 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
324
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Stavrou EX |
Year: |
2015 |
Journal: |
Blood |
Title: |
Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. |
Volume: |
125 |
Issue: |
4 |
Pages: |
710-9 |
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•
•
•
•
•
|
Publication |
First Author: |
Zwart R |
Year: |
2001 |
Journal: |
Genes Dev |
Title: |
Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes. |
Volume: |
15 |
Issue: |
18 |
Pages: |
2361-6 |
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•
•
•
•
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Publication |
First Author: |
Pauler FM |
Year: |
2005 |
Journal: |
Genome Res |
Title: |
Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements. |
Volume: |
15 |
Issue: |
10 |
Pages: |
1379-87 |
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•
•
•
•
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Publication |
First Author: |
Marcho C |
Year: |
2015 |
Journal: |
Epigenetics Chromatin |
Title: |
Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation. |
Volume: |
8 |
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Pages: |
10 |
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•
•
•
•
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Publication |
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Jones PS |
Year: |
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Journal: |
Eur J Biochem |
Title: |
Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome-proliferator-activated-receptor genes. |
Volume: |
233 |
Issue: |
1 |
Pages: |
219-26 |
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•
•
•
•
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Publication |
First Author: |
Schweifer N |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene. |
Volume: |
43 |
Issue: |
3 |
Pages: |
285-97 |
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•
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Publication |
First Author: |
Johnson HL |
Year: |
2013 |
Journal: |
BMC Genomics |
Title: |
Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption. |
Volume: |
14 |
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Pages: |
678 |
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•
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•
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Publication |
First Author: |
Zwart R |
Year: |
2001 |
Journal: |
Mamm Genome |
Title: |
Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb. |
Volume: |
12 |
Issue: |
9 |
Pages: |
734-40 |
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•
•
•
•
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Publication |
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Vaughan KT |
Year: |
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Journal: |
Genomics |
Title: |
Multiple mouse chromosomal loci for dynein-based motility. |
Volume: |
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Issue: |
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Pages: |
29-38 |
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•
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Publication |
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Year: |
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Journal: |
Genomics |
Title: |
Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. |
Volume: |
45 |
Issue: |
2 |
Pages: |
313-9 |
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•
•
•
•
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Publication |
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Marine JC |
Year: |
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Mamm Genome |
Title: |
Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. |
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•
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Nature |
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High-throughput discovery of novel developmental phenotypes. |
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International Committee on Standardized Genetic Nomenclature for Mice |
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Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
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Publication |
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International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
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Publication |
First Author: |
Velocigene |
Year: |
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Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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Publication |
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Wellcome Trust Sanger Institute |
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MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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International Mouse Strain Resource |
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Database Download |
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MGI download of germline transmission data for alleles from IMSR strain data |
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Publication |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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Database Release |
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Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
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Genetic determinants of micronucleus formation in vivo. |
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A conditional knockout resource for the genome-wide study of mouse gene function. |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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MGI Sequence Curation Reference |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Functional annotation of a full-length mouse cDNA collection. |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
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Mouse T31 Radiation Hybrid Data Load |
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The Gene Ontology Consortium |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
El-Hashim AZ |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma. |
Volume: |
14 |
Issue: |
11 |
Pages: |
e0224163 |
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Gene |
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Gene |
Type: |
gene |
Organism: |
chimpanzee |
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Gene |
Type: |
gene |
Organism: |
frog, western clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Allele |
Name: |
MAS1 oncogene; wild type |
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Allele |
Name: |
MAS1 oncogene; targeted mutation 1, Michael Bader |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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Allele |
Name: |
MAS1 oncogene; targeted mutation 1, Velocigene |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
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Allele |
Name: |
MAS1 oncogene; targeted mutation 1.1, Velocigene |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
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Allele |
Name: |
MAS1 oncogene; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
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Allele |
Name: |
MAS1 oncogene; endonuclease-mediated mutation 1, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
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Strain |
Attribute String: |
coisogenic, targeted mutation |
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Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
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Allele |
Name: |
MAS1 oncogene; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
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Allele |
Name: |
MAS1 oncogene; targeted mutation 1e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
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Strain |
Attribute String: |
coisogenic |
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Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
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Allele |
Name: |
MAS1 oncogene; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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