| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:6406848 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750320 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6406977 |
| Age: |
embryonic day 12.5 |
| Image: |
2 - E12.5 |
|
| Specimen Label: |
2 - E12.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6406848 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750324 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:6406977 |
| Age: |
embryonic day 16.5 |
| Image: |
2 - E16.5 |
|
| Specimen Label: |
2 - E16.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6406848 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750327 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6406977 |
| Age: |
postnatal newborn |
| Image: |
2 - neonate |
|
| Specimen Label: |
2 - neonate |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6406848 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:6406977 |
| Age: |
embryonic day 14.5 |
| Image: |
2 - E14.5 |
|
| Specimen Label: |
2 - E14.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6693145 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1861900 |
|
| Specimen Label: |
UC Davis_1861900 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6693145 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1861901 |
|
| Specimen Label: |
UC Davis_1861901 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6693145 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1861902 |
|
| Specimen Label: |
UC Davis_1861902 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6693145 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1861909 |
|
| Specimen Label: |
UC Davis_1861909 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stegbauer J |
| Year: |
2019 |
| Journal: |
J Vasc Surg |
| Title: |
Mas receptor deficiency augments angiotensin II-induced atherosclerosis and aortic aneurysm ruptures in hypercholesterolemic male mice. |
| Volume: |
70 |
| Issue: |
5 |
| Pages: |
1658-1668.e1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suski M |
| Year: |
2013 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The influence of angiotensin-(1-7) Mas receptor agonist (AVE 0991) on mitochondrial proteome in kidneys of apoE knockout mice. |
| Volume: |
1834 |
| Issue: |
12 |
| Pages: |
2463-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
von Bohlen und Halbach O |
| Year: |
2001 |
| Journal: |
Regul Pept |
| Title: |
Genetic deletion of angiotensin AT2 receptor leads to increased cell numbers in different brain structures of mice. |
| Volume: |
99 |
| Issue: |
2-3 |
| Pages: |
209-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cao X |
| Year: |
2022 |
| Journal: |
Elife |
| Title: |
ACE2 pathway regulates thermogenesis and energy metabolism. |
| Volume: |
11 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fang C |
| Year: |
2013 |
| Journal: |
Blood |
| Title: |
Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation. |
| Volume: |
121 |
| Issue: |
15 |
| Pages: |
3023-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nozato S |
| Year: |
2019 |
| Journal: |
Clin Sci (Lond) |
| Title: |
Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice. |
| Volume: |
133 |
| Issue: |
18 |
| Pages: |
2005-2018 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2016 |
| Journal: |
Neuropharmacology |
| Title: |
Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors. |
| Volume: |
105 |
|
| Pages: |
114-123 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song LN |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism. |
| Volume: |
34 |
| Issue: |
12 |
| Pages: |
16291-16306 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Villar AJ |
| Year: |
1994 |
| Journal: |
Nat Genet |
| Title: |
Parental imprinting of the Mas protooncogene in mouse. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
373-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dadam FM |
| Year: |
2017 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Sex chromosome complement involvement in angiotensin receptor sexual dimorphism. |
| Volume: |
447 |
|
| Pages: |
98-105 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rooney RJ |
| Year: |
1998 |
| Journal: |
Mamm Genome |
| Title: |
Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
320-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ali Q |
| Year: |
2016 |
| Journal: |
J Renin Angiotensin Aldosterone Syst |
| Title: |
Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin II type 2 receptor/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury. |
| Volume: |
17 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giani JF |
| Year: |
2012 |
| Journal: |
Growth Horm IGF Res |
| Title: |
Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice. |
| Volume: |
22 |
| Issue: |
6 |
| Pages: |
224-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cebra-Thomas JA |
| Year: |
1992 |
| Journal: |
Genomics |
| Title: |
Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting. |
| Volume: |
13 |
| Issue: |
2 |
| Pages: |
444-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Esteban V |
| Year: |
2009 |
| Journal: |
PLoS One |
| Title: |
Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. |
| Volume: |
4 |
| Issue: |
4 |
| Pages: |
e5406 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cuffe JS |
| Year: |
2014 |
| Journal: |
Placenta |
| Title: |
The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. |
| Volume: |
35 |
| Issue: |
11 |
| Pages: |
953-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohshima K |
| Year: |
2014 |
| Journal: |
Hypertension |
| Title: |
Possible role of angiotensin-converting enzyme 2 and activation of angiotensin II type 2 receptor by angiotensin-(1-7) in improvement of vascular remodeling by angiotensin II type 1 receptor blockade. |
| Volume: |
63 |
| Issue: |
3 |
| Pages: |
e53-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muñoz MC |
| Year: |
2014 |
| Journal: |
J Endocrinol |
| Title: |
Downregulation of the ACE2/Ang-(1-7)/Mas axis in transgenic mice overexpressing GH. |
| Volume: |
221 |
| Issue: |
2 |
| Pages: |
215-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Castro CH |
| Year: |
2005 |
| Journal: |
Hypertension |
| Title: |
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. |
| Volume: |
46 |
| Issue: |
4 |
| Pages: |
937-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang H |
| Year: |
1999 |
| Journal: |
J Neurosci |
| Title: |
Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors. |
| Volume: |
19 |
| Issue: |
12 |
| Pages: |
4938-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
e0128216 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meighan-Mantha RL |
| Year: |
1999 |
| Journal: |
J Biol Chem |
| Title: |
The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. |
| Volume: |
274 |
| Issue: |
46 |
| Pages: |
33166-76 |
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•
•
•
•
|
| Publication |
| First Author: |
Callera GE |
| Year: |
2016 |
| Journal: |
Biosci Rep |
| Title: |
Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis. |
| Volume: |
36 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Himmelbauer H |
| Year: |
1994 |
| Journal: |
Mamm Genome |
| Title: |
High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci. |
| Volume: |
5 |
| Issue: |
12 |
| Pages: |
814-6 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
324
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stavrou EX |
| Year: |
2015 |
| Journal: |
Blood |
| Title: |
Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. |
| Volume: |
125 |
| Issue: |
4 |
| Pages: |
710-9 |
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•
•
•
•
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Zwart R |
| Year: |
2001 |
| Journal: |
Genes Dev |
| Title: |
Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes. |
| Volume: |
15 |
| Issue: |
18 |
| Pages: |
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Pauler FM |
| Year: |
2005 |
| Journal: |
Genome Res |
| Title: |
Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements. |
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10 |
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•
•
•
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Marcho C |
| Year: |
2015 |
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Epigenetics Chromatin |
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Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation. |
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8 |
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| Pages: |
10 |
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•
•
•
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Eur J Biochem |
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Genomics |
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Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene. |
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BMC Genomics |
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Mamm Genome |
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Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb. |
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International Knockout Mouse Consortium |
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Database Download |
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MGI download of modified allele data from IKMC and creation of new knockout alleles |
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2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
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| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
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•
•
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•
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| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
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•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
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| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
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•
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| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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•
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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•
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•
•
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| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
El-Hashim AZ |
| Year: |
2019 |
| Journal: |
PLoS One |
| Title: |
Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma. |
| Volume: |
14 |
| Issue: |
11 |
| Pages: |
e0224163 |
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| Gene |
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•
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•
•
•
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| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
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•
•
•
•
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| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
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•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; wild type |
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•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; targeted mutation 1, Michael Bader |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; targeted mutation 1, Velocigene |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; targeted mutation 1.1, Velocigene |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; endonuclease-mediated mutation 2, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; targeted mutation 1e, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
MAS1 oncogene; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|