Type |
Details |
Score |
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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•
•
•
•
•
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
ncRNA Gene |
Type: |
lncRNA_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Allele |
Name: |
promoter of Mat2a antisense radiation induced circulating long non-coding RNA; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Allele |
Name: |
promoter of Mat2a antisense radiation induced circulating long non-coding RNA; gene trap IST14098B7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
lncRNA Gene |
Type: |
lncRNA_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
methionine adenosyltransferase 1A; targeted mutation 1, Jose M Mato |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu SC |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. |
Volume: |
98 |
Issue: |
10 |
Pages: |
5560-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
MartÃnez-Chantar ML |
Year: |
2002 |
Journal: |
FASEB J |
Title: |
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. |
Volume: |
16 |
Issue: |
10 |
Pages: |
1292-4 |
|
•
•
•
•
•
|
Allele |
Name: |
methionine adenosyltransferase 2A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2004 |
Journal: |
FASEB J |
Title: |
Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A. |
Volume: |
18 |
Issue: |
7 |
Pages: |
914-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
MartÃnez-Chantar ML |
Year: |
2006 |
Journal: |
Gastroenterology |
Title: |
S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase. |
Volume: |
131 |
Issue: |
1 |
Pages: |
223-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
SantamarÃa E |
Year: |
2006 |
Journal: |
J Proteome Res |
Title: |
Molecular profiling of hepatocellular carcinoma in mice with a chronic deficiency of hepatic s-adenosylmethionine: relevance in human liver diseases. |
Volume: |
5 |
Issue: |
4 |
Pages: |
944-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barbier-Torres L |
Year: |
2024 |
Journal: |
Int J Biol Sci |
Title: |
S-Adenosylmethionine Negatively Regulates the Mitochondrial Respiratory Chain Repressor MCJ in the Liver. |
Volume: |
20 |
Issue: |
4 |
Pages: |
1218-1237 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prudova A |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity. |
Volume: |
103 |
Issue: |
17 |
Pages: |
6489-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tomasi ML |
Year: |
2009 |
Journal: |
Gastroenterology |
Title: |
S-adenosylmethionine regulates apurinic/apyrimidinic endonuclease 1 stability: implication in hepatocarcinogenesis. |
Volume: |
136 |
Issue: |
3 |
Pages: |
1025-36 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mat1a/Mat1a |
Background: |
involves: 129/Sv * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
METTL16 is an U6 snRNA methyltransferase that methylates adenosine residues of a subset of RNAs. It plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts [].This entry also includes PsiM from Psilocybe cubensis. PsiM is part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product. It serves as a methyltransferase that catalyze iterative N-methyl transfer as the terminal biosynthetic step []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Shima H |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1. |
Volume: |
21 |
Issue: |
12 |
Pages: |
3354-3363 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Pendleton KE |
Year: |
2017 |
Journal: |
Cell |
Title: |
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. |
Volume: |
169 |
Issue: |
5 |
Pages: |
824-835.e14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng F |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Leptin promotes methionine adenosyltransferase 2A expression in hepatic stellate cells by the downregulation of E2F-4 via the β-catenin pathway. |
Volume: |
34 |
Issue: |
4 |
Pages: |
5578-5589 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ryan DP |
Year: |
2017 |
Journal: |
Mol Psychiatry |
Title: |
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Firestone RS |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Transition state analogue of MTAP extends lifespan of APCMin/+ mice. |
Volume: |
11 |
Issue: |
1 |
Pages: |
8844 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fricke J |
Year: |
2017 |
Journal: |
Angew Chem Int Ed Engl |
Title: |
Enzymatic Synthesis of Psilocybin. |
Volume: |
56 |
Issue: |
40 |
Pages: |
12352-12355 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
553
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
215
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
593
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|