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Search results 301 to 327 out of 327 for Mcm5

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Type Details Score
DO Term
GO Term
Allele
Name: transgene insertion LJ85, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Zeng A
Year: 2013
Journal: J Cell Biol
Title: Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells.
Volume: 201
Issue: 3
Pages: 409-25
Publication
First Author: Seroussi E
Year: 1999
Journal: Genomics
Title: TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.
Volume: 57
Issue: 3
Pages: 380-8
Publication
First Author: Hsu I
Year: 2014
Journal: Carcinogenesis
Title: Suppression of ERβ signaling via ERβ knockout or antagonist protects against bladder cancer development.
Volume: 35
Issue: 3
Pages: 651-61
Publication
First Author: Laresgoiti U
Year: 2013
Journal: Nucleic Acids Res
Title: E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes.
Volume: 41
Issue: 22
Pages: 10185-98
Publication
First Author: Chuang CH
Year: 2012
Journal: Nucleic Acids Res
Title: Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.
Volume: 40
Issue: 11
Pages: 4914-24
Publication
First Author: Kukimoto-Niino M
Year: 2008
Journal: Structure
Title: Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases.
Volume: 16
Issue: 10
Pages: 1478-90
Publication
First Author: Nagashima K
Year: 2002
Journal: FEBS Lett
Title: Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions.
Volume: 517
Issue: 1-3
Pages: 233-8
Publication
First Author: Oberhofer A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro.
Volume: 114
Issue: 24
Pages: E4714-E4723
Protein Domain
Type: Domain
Description: Melanophilin, also termed SlaC2-a, or exophilin-3, is a GTP-bound form of Rab27A-, myosin Va-, and actin-binding protein present on melanosomes. It is involved in the control of transferring of melanosomes from microtubules to actin filaments. It also functions as a melanocyte type myosin Va (McM5) binding partner and directly activates the actin-activated ATPase activity of McM5 through forming a tripartite protein complex with Rab27A and an actin-based motor myosin Va [,]. SlaC2-a belongs to the Slp homologue lacking C2 domains (Slac2) family. It contains an N-terminal Slp homology domain (SHD), but lacks tandem C2 domains. The SHD consists of two conserved regions, designated SHD1 (Slp homology domain 1) and SHD2, which may function as protein interaction sites []. The SHD1 and SHD2 of SlaC2-a are separated by a putative FYVE zinc finger, which resembles a FYVE-related domain that is structurally similar to the canonical FYVE domains but lacks the three signature sequences: an N-terminal WxxD motif (x for any residue), the central basic R(R/K)HHCRxCG patch, and a C-terminal RVC motif. Moreover, Slac2-a has a middle myosin-binding domain and a C-terminal actin-binding domain [].
Protein
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: false
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
Publication  
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
Publication
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
Publication
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112