|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 385 out of 385 for Med1

<< First    < Previous  |  Next >    Last >>
0.015s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
•
•
•
•
•
Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
•
•
•
•
•
Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
•
•
•
•
•
Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
•
•
•
•
•
Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
•
•
•
•
•
Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
•
•
•
•
•
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
HT Experiment
GSE232190 | Effects of MED1 knock out on dental epithelia
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
HT Experiment
GSE84160 | Med1 is Necessary for Cardiac Function
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
HT Experiment
E-GEOD-50671 | Ablation of coactivator Med1 regulates bulge keratinocyte stem cells and accelerates epidermal regeneration after injury [10wk skin]
Series Id: GSE50671
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Protein Coding Gene
MGI:1333850 | Mbd4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
HT Experiment
E-GEOD-50503 | Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair [mixed stage]
Series Id: GSE50503
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
HT Experiment
E-GEOD-50502 | Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair [maturation stage]
Series Id: GSE50502
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
HT Experiment
E-GEOD-50501 | Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair [CL stage]
Series Id: GSE50501
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
14614141 | J:86981
First Author: Cortellino S
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity.
Volume: 100
Issue: 25
Pages: 15071-6
•
•
•
•
•
Protein
Q9JHS9
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
•
•
•
•
•
DO Term
DOID:0070303 | multiple epiphyseal dysplasia 1
•
•
•
•
•
Interaction Experiment
Li H (2008)
Description: The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma.
•
•
•
•
•
Publication
10930409 | -
First Author: Petronzelli F
Year: 2000
Journal: J Biol Chem
Title: Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase.
Volume: 275
Issue: 42
Pages: 32422-9
•
•
•
•
•
Protein
Q3UL36
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
•
•
•
•
•
Protein
A0A140LIS5
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
•
•
•
•
•
Publication
21454576 | -
First Author: Zhang D
Year: 2011
Journal: J Biol Chem
Title: Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growth.
Volume: 286
Issue: 20
Pages: 17746-54
•
•
•
•
•
Protein Domain
IPR033371 | ARGLU1
Type: Family
Description: The arginine and glutamate-rich 1 (ARGLU1) family of proteins is found in metazoa and plants. In mammals, ARGLU1 cooperates with MED1 to regulate estrogen receptor-mediated gene transcription [].
•
•
•
•
•
Protein Domain
IPR021419 | Mediator_Med25_VWA
Type: Domain
Description: The overall function of the full-length Med25 is efficiently to coordinate the transcriptional activation of RAR/RXR (retinoic acid receptor/retinoic X receptor) in higher eukaryotic cells. Human Med25 consists of several domains with different binding properties, the N-terminal, VWA domain which is this one, an SD2 domain from residues 229-381, a PTOV(B) or ACID domain from 395-545, an SD2 domain from residues 564-645 and a C-terminal NR box-containing domain (646-650) from 646-747. This VWA or von Willebrand factor type A domain when bound to RAR and the histone acetyltransferase CBP is responsible for recruiting Med1 to the rest of the Mediator complex [].
•
•
•
•
•
Publication
33503407 | J:305187
First Author: Huang Z
Year: 2021
Journal: Mol Cell
Title: The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages.
Volume: 81
Issue: 5
Pages: 953-968.e9
•
•
•
•
•
Publication
33691110 | J:306410
First Author: Yang Y
Year: 2021
Journal: Cell Rep
Title: Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Volume: 34
Issue: 10
Pages: 108822
•
•
•
•
•
Publication
27376239 | J:277922
First Author: Shin HY
Year: 2016
Journal: Nat Genet
Title: Hierarchy within the mammary STAT5-driven Wap super-enhancer.
Volume: 48
Issue: 8
Pages: 904-911
•
•
•
•
•
Protein
A0A140LHM8
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
•
•
•
•
•
Protein
A0A140LHI1
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
•
•
•
•
•
Protein
A0A140LJ84
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: false
•
•
•
•
•
Publication
24245781 | J:215727
First Author: Mizuta S
Year: 2014
Journal: Genes Cells
Title: CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function.
Volume: 19
Issue: 1
Pages: 28-51
•
•
•
•
•
Publication
37644036 | J:341119
First Author: Rasool RU
Year: 2023
Journal: Nat Commun
Title: Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Volume: 14
Issue: 1
Pages: 5253
•
•
•
•
•
Publication
28963035 | J:248834
First Author: Chowdhary V
Year: 2017
Journal: Am J Pathol
Title: miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 1 Subfamily A Member 2 and Family 2 Subfamily E Member 1 Expression.
Volume: 187
Issue: 12
Pages: 2758-2774
•
•
•
•
•
Publication
28324010 | J:247311
First Author: Patel R
Year: 2017
Journal: Endocrinology
Title: Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids Through LXRβ Antagonism.
Volume: 158
Issue: 4
Pages: 1034-1047
•
•
•
•
•
Publication
32960220 | J:297997
First Author: Guo X
Year: 2020
Journal: Nucleic Acids Res
Title: Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization.
Volume: 48
Issue: 18
Pages: 10226-10240
•
•
•
•
•
Publication
36232979 | J:330902
 
First Author: Kim U
Year: 2022
Journal: Int J Mol Sci
Title: Mammary-Enriched Transcription Factors Synergize to Activate the Wap Super-Enhancer for Mammary Gland Development.
Volume: 23
Issue: 19
•
•
•
•
•
Publication
11238639 | J:67890
First Author: Arons E
Year: 2001
Journal: J Immunol
Title: Organization and functional analysis of the mouse transporter associated with antigen processing 2 promoter.
Volume: 166
Issue: 6
Pages: 3942-51
•
•
•
•
•
Publication
23221399 | J:194302
First Author: Huszar JM
Year: 2013
Journal: Biol Reprod
Title: MicroRNA 146 (Mir146) modulates spermatogonial differentiation by retinoic acid in mice.
Volume: 88
Issue: 1
Pages: 15
•
•
•
•
•
Publication
23630580 | J:200629
First Author: Zhao W
Year: 2013
Journal: PLoS One
Title: SIMPL enhancement of tumor necrosis factor-α dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function.
Volume: 8
Issue: 4
Pages: e61123
•
•
•
•
•
Publication
24358311 | J:211137
First Author: Kapadia B
Year: 2013
Journal: PLoS One
Title: ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.
Volume: 8
Issue: 12
Pages: e83787
•
•
•
•
•
Publication
24051090 | J:211425
First Author: Ishino R
Year: 2013
Journal: Biochem Biophys Res Commun
Title: FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro.
Volume: 440
Issue: 1
Pages: 125-31
•
•
•
•
•
Publication
32510157 | J:292585
First Author: Sun X
Year: 2020
Journal: Nucleic Acids Res
Title: Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers.
Volume: 48
Issue: 13
Pages: 7182-7196
•
•
•
•
•
Publication
17641689 | J:178274
First Author: Lee HK
Year: 2007
Journal: EMBO J
Title: MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.
Volume: 26
Issue: 15
Pages: 3545-57
•
•
•
•
•
Protein
A0A140LIH0
Organism: Mus musculus/domesticus
Length: 599  
Fragment?: true
•
•
•
•
•
Protein
Q8VCB2
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
•
•
•
•
•
Protein
A0A140LHQ0
Organism: Mus musculus/domesticus
Length: 742  
Fragment?: false
•
•
•
•
•
Protein
A0A140LHG7
Organism: Mus musculus/domesticus
Length: 801  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom