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Search results 301 to 400 out of 414 for Men1

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Type Details Score
Publication
33821572 | J:341516
First Author: Ma J
Year: 2021
Journal: EMBO Mol Med
Title: Menin-regulated Pbk controls high fat diet-induced compensatory beta cell proliferation.
Volume: 13
Issue: 5
Pages: e13524
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Publication
15563473 | J:96882
First Author: Naito J
Year: 2005
Journal: J Biol Chem
Title: Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD.
Volume: 280
Issue: 6
Pages: 4785-91
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Publication
28270438 | J:247077
First Author: Muhammad AB
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB.
Volume: 313
Issue: 2
Pages: E148-E166
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Publication
28609655 | J:242562
First Author: Chen Y
Year: 2017
Journal: Cancer Cell
Title: MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.
Volume: 31
Issue: 6
Pages: 755-770.e6
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Publication
25088994 | J:220119
First Author: Song TY
Year: 2014
Journal: Biochem Biophys Res Commun
Title: The role of tumor suppressor menin in IL-6 regulation in mouse islet tumor cells.
Volume: 451
Issue: 2
Pages: 308-13
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Publication
26927674 | J:234567
First Author: Riedel SS
Year: 2016
Journal: J Clin Invest
Title: MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
Volume: 126
Issue: 4
Pages: 1438-50
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Publication
21788502 | J:175625
First Author: Lin W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Volume: 108
Issue: 33
Pages: 13379-86
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Publication
25136117 | J:214819
First Author: Watanabe Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Volume: 111
Issue: 35
Pages: 12829-34
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Publication
19703992 | J:154938
First Author: Wang P
Year: 2009
Journal: Mol Cell Biol
Title: Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
Volume: 29
Issue: 22
Pages: 6074-85
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Publication
38609433 | J:347360
First Author: Fuentes ME
Year: 2024
Journal: Sci Rep
Title: Combined deletion of MEN1, ATRX and PTEN triggers development of high-grade pancreatic neuroendocrine tumors in mice.
Volume: 14
Issue: 1
Pages: 8510
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Publication
23908472 | J:202501
First Author: Li BE
Year: 2013
Journal: Blood
Title: Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.
Volume: 122
Issue: 12
Pages: 2039-46
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Publication
32821827 | J:312564
First Author: Wasylishen AR
Year: 2020
Journal: Sci Adv
Title: Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo.
Volume: 6
Issue: 32
Pages: eaba8415
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Publication
25591470 | J:250700
First Author: Wijeweera A
Year: 2015
Journal: Biochim Biophys Acta
Title: Gonadotropin gene transcription is activated by menin-mediated effects on the chromatin.
Volume: 1849
Issue: 3
Pages: 328-41
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Publication
16625857 | J:116408
First Author: Donangelo I
Year: 2005
Journal: J Endocrinol Invest
Title: Pathophysiology of pituitary adenomas.
Volume: 28
Issue: 11 Suppl International
Pages: 100-5
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Publication
36098964 | J:330908
First Author: Zhu LY
Year: 2022
Journal: Cancer Res
Title: Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.
Volume: 82
Issue: 22
Pages: 4153-4163
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Publication
21670200 | J:183048
First Author: Yokoyama A
Year: 2011
Journal: J Cell Sci
Title: Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.
Volume: 124
Issue: Pt 13
Pages: 2208-19
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Publication
21239436 | J:173881
First Author: Hughes E
Year: 2011
Journal: Endocrinology
Title: Participation of Akt, menin, and p21 in pregnancy-induced beta-cell proliferation.
Volume: 152
Issue: 3
Pages: 847-55
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Publication
25866973 | J:222720
First Author: Jones M
Year: 2015
Journal: J Clin Invest
Title: Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.
Volume: 125
Issue: 5
Pages: 2007-20
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Publication
16618927 | J:109102
First Author: Terranova R
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.
Volume: 103
Issue: 17
Pages: 6629-34
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Publication
17927973 | J:127545
First Author: Engleka KA
Year: 2007
Journal: Dev Biol
Title: Menin is required in cranial neural crest for palatogenesis and perinatal viability.
Volume: 311
Issue: 2
Pages: 524-37
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Publication
20956546 | J:165919
First Author: Onodera A
Year: 2010
Journal: J Exp Med
Title: STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.
Volume: 207
Issue: 11
Pages: 2493-506
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Publication
15150273 | J:93345
First Author: Sowa H
Year: 2004
Journal: J Biol Chem
Title: Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.
Volume: 279
Issue: 39
Pages: 40267-75
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Publication
17500065 | J:123598
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
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Publication
25133424 | J:215828
First Author: Chamberlain CE
Year: 2014
Journal: J Clin Invest
Title: Menin determines K-RAS proliferative outputs in endocrine cells.
Volume: 124
Issue: 9
Pages: 4093-101
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Publication
16435884 | J:107099
First Author: Smart NG
Year: 2006
Journal: PLoS Biol
Title: Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus.
Volume: 4
Issue: 2
Pages: e39
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Publication
26534984 | J:239946
First Author: Pan FC
Year: 2015
Journal: Development
Title: Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.
Volume: 142
Issue: 21
Pages: 3637-48
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
15153434 | J:90809
 
First Author: Agarwal SK
Year: 2004
Journal: Ann N Y Acad Sci
Title: Molecular pathology of the MEN1 gene.
Volume: 1014
Pages: 189-98
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HT Experiment
E-GEOD-29674 | Differential pancreatic islet global gene expression in young heterozygous Men1 mice and wildtype littermates
Series Id: GSE29674
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
36939378 | J:337707
First Author: Xu J
Year: 2023
Journal: Cancer Res
Title: MEN1 Degradation Induced by Neddylation and the CUL4B-DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression.
Volume: 83
Issue: 13
Pages: 2226-2247
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Publication
1358795 | J:2171
First Author: Rochelle JM
Year: 1992
Journal: Genomics
Title: A linkage map of mouse chromosome 19: definition of comparative mapping relationships with human chromosomes 10 and 11 including the MEN1 locus.
Volume: 14
Issue: 1
Pages: 26-31
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Publication
7587389 | J:29706
First Author: Gobl AE
Year: 1995
Journal: Cytogenet Cell Genet
Title: Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-beta 3 (Plcb3), to chromosome region 19B by FISH.
Volume: 71
Issue: 3
Pages: 257-9
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Allele
Men1<tm1Zqw> | MGI:2664869
Name: multiple endocrine neoplasia 1; targeted mutation 1, Zhao-Qi Wang
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129/Sv * 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
E-GEOD-26978 | Expression data from pancreatic islets from Men1flf RIP-Cre mice, Rbp2flf RIP-Cre mice, Men1flf Rbp2flf RIP-Cre mice and matched control
Series Id: GSE26978
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Men1<tm1Ctre> | MGI:2158697
Name: multiple endocrine neoplasia 1; targeted mutation 1, Judy S Crabtree
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout
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Allele
Men1<tm1Gfk> | MGI:2384620
Name: multiple endocrine neoplasia 1; targeted mutation 1, Graham F Kay
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Men1<tm1.1Gfk> | MGI:2384622
Name: multiple endocrine neoplasia 1; targeted mutation 1.1, Graham F Kay
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Men1<tm1.2Zqw> | MGI:2675250
Name: multiple endocrine neoplasia 1; targeted mutation 1, Zhao-Qi Wang
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Men1<tm2.1Gfk> | MGI:3810641
Name: multiple endocrine neoplasia 1; targeted mutation 2.1, Graham F Kay
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Men1<tm1Rvt> | MGI:5461232
Name: multiple endocrine neoplasia 1; targeted mutation 1, Rajesh V Thakker
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Men1<em1Smoc> | MGI:7291029
Name: multiple endocrine neoplasia 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein
Q64213
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
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Protein
Q64213-3
Organism: Mus musculus/domesticus
Length: 639  
Fragment?: false
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Protein
Q64213-2
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
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Protein
O88559
Organism: Mus musculus/domesticus
Length: 611  
Fragment?: false
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Protein
E9PV51
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
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Protein
D3YZC2
Organism: Mus musculus/domesticus
Length: 576  
Fragment?: false
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Protein
F8WHD9
Organism: Mus musculus/domesticus
Length: 616  
Fragment?: false
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Protein
F7CJP6
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
A0A494BB64
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
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Protein
F6ZTV9
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: true
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Protein
A0A0R4J1I3
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
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Publication
12145286 | -
First Author: Yaguchi H
Year: 2002
Journal: J Biol Chem
Title: Menin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23.
Volume: 277
Issue: 41
Pages: 38197-204
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Publication
21740816 | -
First Author: Zhang H
Year: 2011
Journal: Chin Med J (Engl)
Title: Menin expression is regulated by transforming growth factor beta signaling in leukemia cells.
Volume: 124
Issue: 10
Pages: 1556-62
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Protein Domain
IPR007747 | Menin
Type: Family
Description: The tumour suppressor gene MEN1 is mutated in patients with a dominantly inherited tumour syndrome, multiple endocrine neoplasia type 1 (MEN1) []. The MEN1 gene encodes a protein known as Menin, which is located predominantly in the nucleus. Menin has been shown to interact with the mixed lineage leukemia (MLL) protein, a histone H3 lysine 4 methyltransferase, and plays a critical role in hematopoiesis and leukemogenesis [].
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Genotype
Genotype
Symbol: Men1/Men1 Tg(Ins2-cre)23Herr/?
Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129T2/SvEms * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129T2/SvEms * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1 Tg(Ins2-cre)25Mgn/?
Background: involves: 129T2/SvEms * C57BL/6 * C57BL/6J * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:10017 | multiple endocrine neoplasia type 1
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Strain
MGI:7623429 | C57BL/6JSmoc-Men1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:3849724 | B6;129P2-Men1<tm1Zqw>/Orl
Attribute String: targeted mutation, mutant stock
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Strain
MGI:5297109 | 129-Men1<tm1Zqw>/Orl
Attribute String: targeted mutation, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Men1/Men1
Background: either: (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Men1/Men1<+>
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
28965973 | J:263920
 
First Author: Li JWY
Year: 2018
Journal: Mol Cell Endocrinol
Title: MENIN loss as a tissue-specific driver of tumorigenesis.
Volume: 469
Pages: 98-106
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Publication
8670283 | J:33574
First Author: Lagercrantz J
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Sequence and expression of the mouse homologue to human phospholipase C beta3 neighboring gene.
Volume: 223
Issue: 2
Pages: 335-40
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Publication
24912192 | J:212103
First Author: Ohki R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.
Volume: 111
Issue: 23
Pages: E2404-13
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