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Search results 301 to 336 out of 336 for Mid2

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Type Details Score
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Probable E3 ubiquitin-protein ligase MID2
Type: chain
End: 705
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Publication
11806752 | J:205681
 
First Author: Short KM
Year: 2002
Journal: BMC Cell Biol
Title: MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.
Volume: 3
Pages: 1
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Allele
Mid2<em1Smoc> | MGI:7291073
Name: midline 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
30941058 | -
 
First Author: Zanchetta ME
Year: 2019
Journal: Front Physiol
Title: Emerging Roles of the TRIM E3 Ubiquitin Ligases MID1 and MID2 in Cytokinesis.
Volume: 10
Pages: 274
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Strain
MGI:6475786 | C57BL/6JSmoc-Mid2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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DO Term
DOID:0112048 | non-syndromic X-linked intellectual disability 101
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Interaction Experiment
Short KM (2002)
Description: MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.
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Protein Domain
IPR035752 | SPRY/PRY_TRIM1
Type: Domain
Description: This domain, consisting of the distinct N-terminal PRY subdomain followed by the SPRY subdomain, is found at the C terminus of TRIM1 (also known as MID2 or midline 2). MID2 and its close homologue, TRIM18 (also known as MID1), both contain a B30.2-like domain at their C terminus and a single fibronectin type III (FN3) motif between it and their N-terminal RBCC domain. Mid1 and Mid2 are ubiquitin ligases that regulate microtubule dynamics and whose mutation is associated with X-linked developmental disorders. Mid2 regulates cell division through the ubiquitination of astrin on K409, which is critical for its degradation and proper cytokinesis [].
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Publication
27367845 | -
First Author: Wright KM
Year: 2016
Journal: FEBS J
Title: Solution structure of the microtubule-targeting COS domain of MID1.
Volume: 283
Issue: 16
Pages: 3089-102
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Protein Domain
IPR040859 | Midline-1_COS
Type: Domain
Description: This entry represents the COS domain found in the C-I subfamily of the tripartite motif (TRIM) family of E3 ubiquitin ligases.The C-1 subfamily includes MID1 (TRIM18), MID2 (TRIM1), TRIM9, TNL (TRIM67), TRIM36 and TRIFIC (TRIM46) [, , ]. The C-I subfamily contains C-terminal FNIII and B30.2 domains which are associated with microtubules [, ]. C-I subfamily members also contain a relatively conserved region of approximately 60 amino acids, termed the C-terminal subgroup One Signature (COS) domain []. The human Midline-1 (MID1) COS domain has a helix-loop-helix structure in which the N- and C-terminal ends are in close proximity []. Deletion of the human MID1 COS domain does not affect MID1 dimerisation but disrupts localisation to the microtubules [].The COS domain is also observed within the TRIM C-II subgroup, which consists of the MURF1-3 proteins that do not contain the FNIII and B30.2domains. MUF1-3 proteins are also associated with microtubules [].
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Publication
16434393 | -
First Author: Short KM
Year: 2006
Journal: J Biol Chem
Title: Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.
Volume: 281
Issue: 13
Pages: 8970-80
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Protein
J3JSM8
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Protein
E9PUI3
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Protein
Q6PD02
Organism: Mus musculus/domesticus
Length: 400  
Fragment?: false
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Protein
Q3TVH5
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
B1AUZ9
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
Q3TC52
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein
Q80WG7
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
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Protein
Q7TNM2
Organism: Mus musculus/domesticus
Length: 759  
Fragment?: false
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Protein
O70583
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
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Protein
B1AV01
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
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Protein
E9Q3A0
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
D3YXA6
Organism: Mus musculus/domesticus
Length: 736  
Fragment?: false
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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