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Search results 301 to 400 out of 506 for Mlkl

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Stage: TS17
Assay Id: MGI:7643501
Age: embryonic day 10.5
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691017
Stage: TS17
Assay Id: MGI:7643501
Age: embryonic day 10.5
Image: S4
Specimen Label: KO
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:7643466
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Stage: TS17
Assay Id: MGI:7643502
Age: embryonic day 10.5
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:7643466
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691017
Stage: TS17
Assay Id: MGI:7643502
Age: embryonic day 10.5
Image: S4
Specimen Label: KO
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:7643466
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:7643505
Age: postnatal day 1
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:7643466
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:7643505
Age: postnatal day 1
Image: S4
Specimen Label: KO
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:7643506
Age: postnatal day 1
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2024-05-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752527
Stage: TS27
Assay Id: MGI:7643506
Age: postnatal day 1
Image: S4
Specimen Label: KO
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7643479
Age: postnatal day 1
Image: 1G left
Note: Positive cells distributed mainly in epidermal layer. Approximately 22-23% co-expressed CD31/Pecam1.
Specimen Label: 1G left
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7643479
Age: postnatal day 1
Image: 1G right
Note: Positive cells distributed mainly in epidermal layer. Approximately 22-23% co-expressed Sox18.
Specimen Label: 1G right
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7643479
Age: postnatal day 1
Image: S2B
Note: Positive cells distributed mainly in epidermal layer.
Specimen Label: S2B
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752827
Stage: TS27
Assay Id: MGI:7643479
Age: postnatal day 1
Image: S2B
Note: No co-expression with Pdgfrb.
Specimen Label: S2B
Detected: false
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752827
Stage: TS27
Assay Id: MGI:7643479
Age: postnatal day 1
Image: S2B
Note: No co-expression with Pdgfrb.
Specimen Label: S2B
Detected: false
Specimen Num: 6
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•
GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7643479
Age: embryonic day 10.5
Image: 1E left
Note: Expressed mainly at the surface or the interface between cortex and ventricle. Approximately, 45.5% co-expressed with CD31/Pecam1.
Specimen Label: 1E left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7643479
Age: embryonic day 10.5
Image: 1E right
Note: Expressed mainly at the surface or the interface between cortex and ventricle. Approximately, 31.4% co-expressed with Sox18.
Specimen Label: 1E right
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7643479
Age: embryonic day 10.5
Image: S2A
Note: Expressed mainly at the surface or the interface between cortex and ventricle.
Specimen Label: S2A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691017
Stage: TS17
Assay Id: MGI:7643479
Age: embryonic day 10.5
Image: S2A
Note: No co-expression with Pdgfrb.
Specimen Label: S2A
Detected: false
Specimen Num: 5
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•
GXD Expression
GXD Expression
Probe: MGI:6196374
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7643486
Age: postnatal day 1
Image: S1
Note: Co-localized with propidium iodide (PI) labeling confirmed necroptosis.
Specimen Label: S1
Detected: true
Specimen Num: 1
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Publication
31748744 | J:285930
First Author: Fritsch M
Year: 2019
Journal: Nature
Title: Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.
Volume: 575
Issue: 7784
Pages: 683-687
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Publication
27819682 | J:242990
First Author: Newton K
Year: 2016
Journal: Nature
Title: RIPK1 inhibits ZBP1-driven necroptosis during development.
Volume: 540
Issue: 7631
Pages: 129-133
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Publication
38548850 | J:348283
First Author: Solon M
Year: 2024
Journal: Cell Death Differ
Title: ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1.
Volume: 31
Issue: 5
Pages: 672-682
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Publication
31659279 | J:297034
First Author: Someda M
Year: 2020
Journal: Cell Death Differ
Title: Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
Volume: 27
Issue: 5
Pages: 1539-1553
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Publication
37576598 | J:339076
 
First Author: Meng H
Year: 2023
Journal: Front Cell Dev Biol
Title: Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation.
Volume: 11
Pages: 1229788
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Publication
25132550 | J:217312
First Author: Dannappel M
Year: 2014
Journal: Nature
Title: RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
Volume: 513
Issue: 7516
Pages: 90-4
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Publication
31132747 | J:286073
 
First Author: Shindo R
Year: 2019
Journal: iScience
Title: Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis.
Volume: 15
Pages: 536-551
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Publication
31511692 | J:281456
First Author: Newton K
Year: 2019
Journal: Nature
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Volume: 574
Issue: 7778
Pages: 428-431
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Publication
29695863 | J:261640
First Author: Peltzer N
Year: 2018
Journal: Nature
Title: LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Volume: 557
Issue: 7703
Pages: 112-117
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Publication
18414056 | J:137358
First Author: Bisson N
Year: 2008
Journal: Cell Cycle
Title: Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.
Volume: 7
Issue: 7
Pages: 909-16
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Publication
38355725 | J:353414
First Author: Shojaie L
Year: 2024
Journal: Cell Death Dis
Title: Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors.
Volume: 15
Issue: 2
Pages: 140
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Publication
33444549 | J:305557
First Author: Liu Z
Year: 2021
Journal: Immunity
Title: A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.
Volume: 54
Issue: 2
Pages: 247-258.e7
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Publication
26559832 | J:235313
First Author: Yu X
Year: 2015
Journal: J Virol
Title: Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1.
Volume: 90
Issue: 2
Pages: 1088-95
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Publication
30050136 | J:289074
First Author: Guo H
Year: 2018
Journal: Cell Death Dis
Title: Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1.
Volume: 9
Issue: 8
Pages: 816
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Publication
29415885 | J:290238
 
First Author: Imamura M
Year: 2018
Journal: JCI Insight
Title: RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
Volume: 3
Issue: 3
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Publication
34135886 | J:337277
 
First Author: Liu ZZ
Year: 2021
Journal: Front Immunol
Title: STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis.
Volume: 12
Pages: 636861
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Publication
32797196 | J:310106
 
First Author: Shubina M
Year: 2020
Journal: J Exp Med
Title: Necroptosis restricts influenza A virus as a stand-alone cell death mechanism.
Volume: 217
Issue: 11
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Publication
35288534 | J:322823
First Author: Tonnus W
Year: 2022
Journal: Cell Death Dis
Title: Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury.
Volume: 13
Issue: 3
Pages: 236
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Publication
27524612 | J:238947
First Author: Kitur K
Year: 2016
Journal: Cell Rep
Title: Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.
Volume: 16
Issue: 8
Pages: 2219-2230
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Publication
38341853 | J:346154
First Author: Huang Y
Year: 2024
Journal: Cell Rep
Title: Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves.
Volume: 43
Issue: 2
Pages: 113753
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Publication
31454332 | J:293714
First Author: Tisch N
Year: 2019
Journal: J Clin Invest
Title: Caspase-8 modulates physiological and pathological angiogenesis during retina development.
Volume: 129
Issue: 12
Pages: 5092-5107
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Publication
30131368 | J:281795
 
First Author: Raju S
Year: 2018
Journal: Sci Signal
Title: Kinase domain dimerization drives RIPK3-dependent necroptosis.
Volume: 11
Issue: 544
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Publication
29875323 | J:280175
 
First Author: Sureshbabu A
Year: 2018
Journal: JCI Insight
Title: RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction.
Volume: 3
Issue: 11
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Publication
30683914 | J:296194
First Author: Yang L
Year: 2019
Journal: Cell Death Differ
Title: TAK1 regulates endothelial cell necroptosis and tumor metastasis.
Volume: 26
Issue: 10
Pages: 1987-1997
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Publication
36719079 | J:336313
First Author: Fleischmann M
Year: 2023
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Cigarette smoke depletes alveolar macrophages and delays clearance of Legionella pneumophila.
Volume: 324
Issue: 3
Pages: L373-L384
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Publication
36155655 | J:336980
   
First Author: Cohen H
Year: 2022
Journal: Elife
Title: Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors.
Volume: 11
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Publication
35393408 | J:325464
First Author: Ke FFS
Year: 2022
Journal: Cell Death Dis
Title: Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood.
Volume: 13
Issue: 4
Pages: 317
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Publication
30944222 | J:274277
First Author: Motwani M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models.
Volume: 116
Issue: 16
Pages: 7941-7950
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Publication
30770249 | J:282515
First Author: Li X
Year: 2019
Journal: Immunity
Title: O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Volume: 50
Issue: 3
Pages: 576-590.e6
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Publication
27840306 | J:255640
First Author: Shen C
Year: 2017
Journal: Biochim Biophys Acta
Title: Aldehyde dehydrogenase 2 deficiency negates chronic low-to-moderate alcohol consumption-induced cardioprotecion possibly via ROS-dependent apoptosis and RIP1/RIP3/MLKL-mediated necroptosis.
Volume: 1863
Issue: 8
Pages: 1912-1918
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Publication
29996103 | J:271251
First Author: Pajuelo D
Year: 2018
Journal: Cell Rep
Title: NAD+ Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis.
Volume: 24
Issue: 2
Pages: 429-440
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Publication
26859455 | J:231452
First Author: Lalaoui N
Year: 2016
Journal: Cancer Cell
Title: Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Volume: 29
Issue: 2
Pages: 145-58
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Publication
27487218 | J:296726
First Author: Strilic B
Year: 2016
Journal: Nature
Title: Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis.
Volume: 536
Issue: 7615
Pages: 215-8
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Publication
29588419 | J:261428
First Author: Martin-Sanchez D
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: TWEAK and RIPK1 mediate a second wave of cell death during AKI.
Volume: 115
Issue: 16
Pages: 4182-4187
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Publication
35711363 | J:351459
 
First Author: Wang Q
Year: 2022
Journal: Front Cardiovasc Med
Title: MG53 Inhibits Necroptosis Through Ubiquitination-Dependent RIPK1 Degradation for Cardiac Protection Following Ischemia/Reperfusion Injury.
Volume: 9
Pages: 868632
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Publication
35064213 | J:342732
First Author: Li X
Year: 2022
Journal: Cell Death Differ
Title: Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia.
Volume: 29
Issue: 8
Pages: 1500-1512
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Publication
34029184 | J:307062
   
First Author: Li D
Year: 2021
Journal: Elife
Title: A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression.
Volume: 10
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Publication
30598363 | J:271922
First Author: Liccardi G
Year: 2019
Journal: Mol Cell
Title: RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
Volume: 73
Issue: 3
Pages: 413-428.e7
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Publication
32971525 | J:297419
First Author: Gitlin AD
Year: 2020
Journal: Nature
Title: Integration of innate immune signalling by caspase-8 cleavage of N4BP1.
Volume: 587
Issue: 7833
Pages: 275-280
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Publication
33109609 | J:300942
First Author: Banoth B
Year: 2020
Journal: J Biol Chem
Title: ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis).
Volume: 295
Issue: 52
Pages: 18276-18283
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Publication
32433961 | J:304688
First Author: Sreenivasan K
Year: 2020
Journal: Cell Rep
Title: Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles.
Volume: 31
Issue: 7
Pages: 107652
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Publication
34752416 | J:325548
 
First Author: Chun N
Year: 2021
Journal: JCI Insight
Title: T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
Volume: 6
Issue: 24
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Publication
27411587 | J:233524
First Author: Höckendorf U
Year: 2016
Journal: Cancer Cell
Title: RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
Volume: 30
Issue: 1
Pages: 75-91
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Publication
38788712 | J:349811
     
First Author: Mannion J
Year: 2024
Journal: Immunity
Title: A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death.
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Publication
27737018 | J:245476
First Author: Philip NH
Year: 2016
Journal: PLoS Pathog
Title: Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death.
Volume: 12
Issue: 10
Pages: e1005910
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Publication
30944411 | J:292202
First Author: Cao M
Year: 2019
Journal: Cell Death Differ
Title: Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection.
Volume: 26
Issue: 12
Pages: 2622-2636
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Publication
33798093 | J:303329
 
First Author: Müller K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Volume: 118
Issue: 12
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Publication
31352002 | J:291197
First Author: Günther C
Year: 2019
Journal: Gastroenterology
Title: Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn's Disease.
Volume: 157
Issue: 5
Pages: 1310-1322.e13
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Publication
28461567 | J:247747
First Author: Saleh D
Year: 2017
Journal: J Immunol
Title: Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.
Volume: 198
Issue: 11
Pages: 4435-4447
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Publication
35859177 | J:331943
First Author: Hubbard NW
Year: 2022
Journal: Nature
Title: ADAR1 mutation causes ZBP1-dependent immunopathology.
Volume: 607
Issue: 7920
Pages: 769-775
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Publication
30635240 | J:279203
First Author: Daniels BP
Year: 2019
Journal: Immunity
Title: The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.
Volume: 50
Issue: 1
Pages: 64-76.e4
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Publication
24019532 | J:204906
First Author: Kaiser WJ
Year: 2013
Journal: J Biol Chem
Title: Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.
Volume: 288
Issue: 43
Pages: 31268-79
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Publication
24813849 | J:214394
First Author: Rickard JA
Year: 2014
Journal: Cell
Title: RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Volume: 157
Issue: 5
Pages: 1175-88
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Publication
25301392 | J:219674
First Author: Zhao Y
Year: 2015
Journal: Diabetologia
Title: Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes.
Volume: 58
Issue: 1
Pages: 140-8
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Publication
32268091 | J:310108
First Author: Donado CA
Year: 2020
Journal: Cell Rep
Title: A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.
Volume: 31
Issue: 1
Pages: 107466
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