Type |
Details |
Score |
Publication |
First Author: |
Gelinas JN |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
ERK and mTOR signaling couple beta-adrenergic receptors to translation initiation machinery to gate induction of protein synthesis-dependent long-term potentiation. |
Volume: |
282 |
Issue: |
37 |
Pages: |
27527-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Distefano G |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1. |
Volume: |
29 |
Issue: |
9 |
Pages: |
2359-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mavrakis M |
Year: |
2006 |
Journal: |
Hum Mol Genet |
Title: |
Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. |
Volume: |
15 |
Issue: |
19 |
Pages: |
2962-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al-Ali H |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury. |
Volume: |
37 |
Issue: |
30 |
Pages: |
7079-7095 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang J |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling. |
Volume: |
110 |
Issue: |
6 |
Pages: |
2270-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai LP |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. |
Volume: |
110 |
Issue: |
48 |
Pages: |
19450-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nie X |
Year: |
2021 |
Journal: |
Dev Biol |
Title: |
mTOR deletion in neural crest cells disrupts cardiac outflow tract remodeling and causes a spectrum of cardiac defects through the mTORC1 pathway. |
Volume: |
477 |
|
Pages: |
241-250 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nieto-González JL |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α. |
Volume: |
116 |
Issue: |
16 |
Pages: |
8000-8009 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nie X |
Year: |
2020 |
Journal: |
Dev Biol |
Title: |
mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. |
Volume: |
467 |
Issue: |
1-2 |
Pages: |
77-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pringle DR |
Year: |
2014 |
Journal: |
J Clin Endocrinol Metab |
Title: |
Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice. |
Volume: |
99 |
Issue: |
5 |
Pages: |
E804-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smink JJ |
Year: |
2009 |
Journal: |
EMBO J |
Title: |
Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB. |
Volume: |
28 |
Issue: |
12 |
Pages: |
1769-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lamming DW |
Year: |
2012 |
Journal: |
Science |
Title: |
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. |
Volume: |
335 |
Issue: |
6076 |
Pages: |
1638-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abe Y |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
TGF-β1 stimulates mitochondrial oxidative phosphorylation and generation of reactive oxygen species in cultured mouse podocytes, mediated in part by the mTOR pathway. |
Volume: |
305 |
Issue: |
10 |
Pages: |
F1477-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tenkerian C |
Year: |
2015 |
Journal: |
Mol Cancer Res |
Title: |
mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress. |
Volume: |
13 |
Issue: |
10 |
Pages: |
1377-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ichimura Y |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. |
Volume: |
51 |
Issue: |
5 |
Pages: |
618-31 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Taneike M |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. |
Volume: |
11 |
Issue: |
3 |
Pages: |
e0152628 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sarbassov DD |
Year: |
2004 |
Journal: |
Curr Biol |
Title: |
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. |
Volume: |
14 |
Issue: |
14 |
Pages: |
1296-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kakumoto K |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
mLST8 Promotes mTOR-Mediated Tumor Progression. |
Volume: |
10 |
Issue: |
4 |
Pages: |
e0119015 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cattin ME |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. |
Volume: |
290 |
Issue: |
44 |
Pages: |
26699-714 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang S |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility. |
Volume: |
294 |
Issue: |
45 |
Pages: |
16756-16764 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sherman DL |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
Arrest of myelination and reduced axon growth when Schwann cells lack mTOR. |
Volume: |
32 |
Issue: |
5 |
Pages: |
1817-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reiling JH |
Year: |
2006 |
Journal: |
Oncogene |
Title: |
Stress and mTORture signaling. |
Volume: |
25 |
Issue: |
48 |
Pages: |
6373-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato T |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein. |
Volume: |
284 |
Issue: |
19 |
Pages: |
12783-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun J |
Year: |
2018 |
Journal: |
Elife |
Title: |
UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. |
Volume: |
7 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kaur S |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses. |
Volume: |
109 |
Issue: |
20 |
Pages: |
7723-8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466880 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3290627 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7467226 |
Age: |
postnatal day 0 |
Image: |
6 |
|
Specimen Label: |
mTOR cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466883 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3290627 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7467228 |
Age: |
postnatal day 0 |
Image: |
6 |
|
Specimen Label: |
mTOR cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466929 |
Assay Type: |
Western blot |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3290623 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7467230 |
Age: |
embryonic day 15.5 |
Image: |
7 |
|
Specimen Label: |
mTOR cKO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7466890 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3290623 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7467231 |
Age: |
embryonic day 15.5 |
Image: |
7 |
|
Specimen Label: |
mTOR cKO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jacków J |
Year: |
2016 |
Journal: |
J Invest Dermatol |
Title: |
Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling. |
Volume: |
136 |
Issue: |
5 |
Pages: |
1031-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chakrabarti P |
Year: |
2010 |
Journal: |
Diabetes |
Title: |
Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage. |
Volume: |
59 |
Issue: |
4 |
Pages: |
775-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang HH |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. |
Volume: |
4 |
Issue: |
7 |
Pages: |
e6189 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Y |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth. |
Volume: |
8 |
Issue: |
1 |
Pages: |
e54221 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikenoue T |
Year: |
2008 |
Journal: |
EMBO J |
Title: |
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. |
Volume: |
27 |
Issue: |
14 |
Pages: |
1919-31 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2549
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Volovelsky O |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Hamartin regulates cessation of mouse nephrogenesis independently of Mtor. |
Volume: |
115 |
Issue: |
23 |
Pages: |
5998-6003 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi L |
Year: |
2019 |
Journal: |
PLoS Biol |
Title: |
TSC1/mTOR-controlled metabolic-epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis. |
Volume: |
17 |
Issue: |
8 |
Pages: |
e3000420 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kassai H |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases. |
Volume: |
7 |
Issue: |
5 |
Pages: |
1626-1639 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alimonti A |
Year: |
2010 |
Journal: |
J Clin Invest |
Title: |
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. |
Volume: |
120 |
Issue: |
3 |
Pages: |
681-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu PJ |
Year: |
2018 |
Journal: |
Nat Neurosci |
Title: |
mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors. |
Volume: |
21 |
Issue: |
6 |
Pages: |
799-802 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshimura R |
Year: |
2016 |
Journal: |
Biosci Biotechnol Biochem |
Title: |
Phosphorylation of 4EBP by oral leucine administration was suppressed in the skeletal muscle of PGC-1α knockout mice. |
Volume: |
80 |
Issue: |
2 |
Pages: |
288-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato A |
Year: |
2010 |
Journal: |
Neurosci Lett |
Title: |
Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR. |
Volume: |
470 |
Issue: |
2 |
Pages: |
115-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caccamo A |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature. |
Volume: |
34 |
Issue: |
23 |
Pages: |
7988-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ray JP |
Year: |
2015 |
Journal: |
Immunity |
Title: |
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. |
Volume: |
43 |
Issue: |
4 |
Pages: |
690-702 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin PM |
Year: |
2003 |
Journal: |
Biol Reprod |
Title: |
Amino acid transport regulates blastocyst implantation. |
Volume: |
69 |
Issue: |
4 |
Pages: |
1101-8 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee K |
Year: |
2010 |
Journal: |
Immunity |
Title: |
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. |
Volume: |
32 |
Issue: |
6 |
Pages: |
743-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robitaille AM |
Year: |
2013 |
Journal: |
Science |
Title: |
Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. |
Volume: |
339 |
Issue: |
6125 |
Pages: |
1320-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao B |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR. |
Volume: |
31 |
Issue: |
4 |
Pages: |
107571 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shin J |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function. |
Volume: |
111 |
Issue: |
8 |
Pages: |
E776-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sciarretta S |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
mTORC2 regulates cardiac response to stress by inhibiting MST1. |
Volume: |
11 |
Issue: |
1 |
Pages: |
125-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roberts DJ |
Year: |
2014 |
Journal: |
Mol Cell |
Title: |
Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition. |
Volume: |
53 |
Issue: |
4 |
Pages: |
521-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kellersch B |
Year: |
2013 |
Journal: |
Blood |
Title: |
Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function. |
Volume: |
121 |
Issue: |
2 |
Pages: |
298-307 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosner M |
Year: |
2008 |
Journal: |
Hum Mol Genet |
Title: |
Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1. |
Volume: |
17 |
Issue: |
19 |
Pages: |
2934-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JH |
Year: |
2015 |
Journal: |
Neuron |
Title: |
Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes. |
Volume: |
85 |
Issue: |
2 |
Pages: |
303-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morimoto N |
Year: |
2007 |
Journal: |
Brain Res |
Title: |
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene. |
Volume: |
1167 |
|
Pages: |
112-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Serra ND |
Year: |
2017 |
Journal: |
Biol Reprod |
Title: |
Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse†. |
Volume: |
96 |
Issue: |
4 |
Pages: |
816-828 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng DM |
Year: |
2015 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A treadmill exercise reactivates the signaling of the mammalian target of rapamycin (mTor) in the skeletal muscles of starved mice. |
Volume: |
456 |
Issue: |
1 |
Pages: |
519-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao J |
Year: |
2019 |
Journal: |
Asian J Androl |
Title: |
Mechanistic target of rapamycin kinase (Mtor) is required for spermatogonial proliferation and differentiation in mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Smrz D |
Year: |
2011 |
Journal: |
Blood |
Title: |
mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells. |
Volume: |
118 |
Issue: |
26 |
Pages: |
6803-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen WH |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function. |
Volume: |
283 |
Issue: |
20 |
Pages: |
13842-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Amiel E |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Inhibition of mechanistic target of rapamycin promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice. |
Volume: |
189 |
Issue: |
5 |
Pages: |
2151-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ortells MC |
Year: |
2012 |
Journal: |
Nucleic Acids Res |
Title: |
Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target of rapamycin. |
Volume: |
40 |
Issue: |
10 |
Pages: |
4368-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao Y |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Rapamycin inhibition of mTORC1 reverses lithium-induced proliferation of renal collecting duct cells. |
Volume: |
305 |
Issue: |
8 |
Pages: |
F1201-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siddappa D |
Year: |
2014 |
Journal: |
Mol Reprod Dev |
Title: |
Mechanistic target of rapamycin (MTOR) signaling during ovulation in mice. |
Volume: |
81 |
Issue: |
7 |
Pages: |
655-65 |
|
•
•
•
•
•
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Publication |
First Author: |
Dunn JLM |
Year: |
2018 |
Journal: |
J Leukoc Biol |
Title: |
Mammalian target of rapamycin regulates a hyperresponsive state in pulmonary neutrophils late after burn injury. |
Volume: |
103 |
Issue: |
5 |
Pages: |
909-918 |
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Publication |
First Author: |
Yang J |
Year: |
2017 |
Journal: |
Int J Cancer |
Title: |
MiR-15a/16 deficiency enhances anti-tumor immunity of glioma-infiltrating CD8+ T cells through targeting mTOR. |
Volume: |
141 |
Issue: |
10 |
Pages: |
2082-2092 |
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Publication |
First Author: |
Motz KM |
Year: |
2023 |
Journal: |
JCI Insight |
Title: |
Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis. |
Volume: |
8 |
Issue: |
11 |
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Publication |
First Author: |
Wall M |
Year: |
2013 |
Journal: |
Cancer Discov |
Title: |
The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence. |
Volume: |
3 |
Issue: |
1 |
Pages: |
82-95 |
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Publication |
First Author: |
Zhong S |
Year: |
2021 |
Journal: |
Mol Neurobiol |
Title: |
GABAergic Interneuron and Neurotransmission Are mTOR-Dependently Disturbed in Experimental Focal Cortical Dysplasia. |
Volume: |
58 |
Issue: |
1 |
Pages: |
156-169 |
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Publication |
First Author: |
RamÃrez-JarquÃn UN |
Year: |
2020 |
Journal: |
Transl Psychiatry |
Title: |
The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior. |
Volume: |
10 |
Issue: |
1 |
Pages: |
336 |
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Publication |
First Author: |
Cong XX |
Year: |
2018 |
Journal: |
Stem Cells |
Title: |
Activation of AKT-mTOR Signaling Directs Tenogenesis of Mesenchymal Stem Cells. |
Volume: |
36 |
Issue: |
4 |
Pages: |
527-539 |
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Publication |
First Author: |
Shu L |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target of rapamycin. |
Volume: |
277 |
Issue: |
19 |
Pages: |
16726-32 |
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Publication |
First Author: |
Cho HJ |
Year: |
2004 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Regulation of adipocyte differentiation and insulin action with rapamycin. |
Volume: |
321 |
Issue: |
4 |
Pages: |
942-8 |
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Publication |
First Author: |
Carracedo A |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. |
Volume: |
118 |
Issue: |
9 |
Pages: |
3065-74 |
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Publication |
First Author: |
Cao R |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock. |
Volume: |
30 |
Issue: |
18 |
Pages: |
6302-14 |
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Publication |
First Author: |
Deli A |
Year: |
2012 |
Journal: |
Behav Brain Res |
Title: |
Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice. |
Volume: |
229 |
Issue: |
2 |
Pages: |
320-4 |
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Publication |
First Author: |
Halloran J |
Year: |
2012 |
Journal: |
Neuroscience |
Title: |
Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. |
Volume: |
223 |
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Pages: |
102-13 |
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Publication |
First Author: |
Schell C |
Year: |
2016 |
Journal: |
Am J Pathol |
Title: |
The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility. |
Volume: |
186 |
Issue: |
2 |
Pages: |
324-36 |
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Publication |
First Author: |
Feng GJ |
Year: |
2020 |
Journal: |
J Cell Physiol |
Title: |
Helicobacter pylori promote inflammation and host defense through the cagA-dependent activation of mTORC1. |
Volume: |
235 |
Issue: |
12 |
Pages: |
10094-10108 |
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Publication |
First Author: |
Serra N |
Year: |
2019 |
Journal: |
Biol Reprod |
Title: |
The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice†. |
Volume: |
100 |
Issue: |
2 |
Pages: |
429-439 |
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Publication |
First Author: |
Carr TD |
Year: |
2015 |
Journal: |
Carcinogenesis |
Title: |
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. |
Volume: |
36 |
Issue: |
4 |
Pages: |
487-97 |
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Publication |
First Author: |
Liu D |
Year: |
2016 |
Journal: |
J Clin Invest |
Title: |
Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning. |
Volume: |
126 |
Issue: |
5 |
Pages: |
1704-16 |
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Publication |
First Author: |
Wieman HL |
Year: |
2007 |
Journal: |
Mol Biol Cell |
Title: |
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. |
Volume: |
18 |
Issue: |
4 |
Pages: |
1437-46 |
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Publication |
First Author: |
Li Y |
Year: |
2020 |
Journal: |
J Cell Mol Med |
Title: |
miRNA-182/Deptor/mTOR axis regulates autophagy to reduce intestinal ischaemia/reperfusion injury. |
Volume: |
24 |
Issue: |
14 |
Pages: |
7873-7883 |
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Publication |
First Author: |
Tian Y |
Year: |
2016 |
Journal: |
Nutrients |
Title: |
Chemopreventive Effect of Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with Modulation of the DEPTOR/mTOR Signaling Pathway. |
Volume: |
8 |
Issue: |
5 |
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Publication |
First Author: |
Byles V |
Year: |
2013 |
Journal: |
Nat Commun |
Title: |
The TSC-mTOR pathway regulates macrophage polarization. |
Volume: |
4 |
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Pages: |
2834 |
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Publication |
First Author: |
González-Terán B |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. |
Volume: |
7 |
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Pages: |
10477 |
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Publication |
First Author: |
Liu Y |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock. |
Volume: |
11 |
Issue: |
1 |
Pages: |
589 |
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Publication |
First Author: |
Xu XY |
Year: |
2009 |
Journal: |
Dev Dyn |
Title: |
Characterization of p70 S6 kinase 1 in early development of mouse embryos. |
Volume: |
238 |
Issue: |
12 |
Pages: |
3025-34 |
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Publication |
First Author: |
Su KH |
Year: |
2016 |
Journal: |
Nat Cell Biol |
Title: |
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. |
Volume: |
18 |
Issue: |
5 |
Pages: |
527-39 |
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Publication |
First Author: |
Yuskaitis CJ |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting. |
Volume: |
40 |
Issue: |
9 |
Pages: |
111278 |
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Publication |
First Author: |
Chang JW |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation. |
Volume: |
6 |
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Pages: |
7218 |
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Publication |
First Author: |
Nasr Z |
Year: |
2013 |
Journal: |
Oncogene |
Title: |
eIF4F suppression in breast cancer affects maintenance and progression. |
Volume: |
32 |
Issue: |
7 |
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861-71 |
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Publication |
First Author: |
Khandker L |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord. |
Volume: |
38 |
Issue: |
9 |
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Publication |
First Author: |
Harty BL |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7. |
Volume: |
10 |
Issue: |
1 |
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2976 |
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Publication |
First Author: |
Soliman MA |
Year: |
2014 |
Journal: |
Sci Signal |
Title: |
The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism. |
Volume: |
7 |
Issue: |
313 |
Pages: |
ra17 |
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