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Search results 301 to 400 out of 414 for Nek7

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Type Details Score
GXD Expression  
Probe: MGI:4417059
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826663
Age: embryonic day 14.5
Image: euxassay_011638_16
Specimen Label: euxassay_011638_16
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371697
Specimen Label: JAX_1371697
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Image: MH1523; Specimen C1522
Specimen Label: MH1523; Specimen C1522
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Specimen Label: MH1523; Specimen C1522
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371674
Specimen Label: JAX_1371674
Detected: true
Specimen Num: 41
GXD Expression  
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Image: MH1523; Specimen C1522
Specimen Label: MH1523; Specimen C1522
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371678
Specimen Label: JAX_1371678
Detected: true
Specimen Num: 45
GXD Expression  
Probe: MGI:2654965
Assay Type: RNA in situ
Annotation Date: 2013-01-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Scattered
Stage: TS28
Assay Id: MGI:5460832
Age: postnatal adult
Image: 3E
Specimen Label: 3E
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Specimen Label: MH1523; Specimen C1522
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Image: MH1523; Specimen C1522
Specimen Label: MH1523; Specimen C1522
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Specimen Label: MH1523; Specimen C1522
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:2654965
Assay Type: RNA in situ
Annotation Date: 2013-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287324
Stage: TS24
Assay Id: MGI:5460832
Age: embryonic day 16.5
Image: 2G
Specimen Label: 2G
Detected: false
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371701
Specimen Label: JAX_1371701
Detected: true
Specimen Num: 24
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371710
Specimen Label: JAX_1371710
Detected: true
Specimen Num: 33
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371706
Specimen Label: JAX_1371706
Detected: true
Specimen Num: 29
GXD Expression    
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MH1523; Specimen C1522
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826626
Stage: TS26
Assay Id: MGI:5540503
Age: embryonic day 17.5
Image: GUDMAP:15290
Specimen Label: GUDMAP:15290
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826628
Stage: TS28
Assay Id: MGI:5540503
Age: postnatal day 84
Image: GUDMAP:15291
Specimen Label: GUDMAP:15291
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772126
Stage: TS26
Assay Id: MGI:5540503
Age: embryonic day 17.5
Image: GUDMAP:15290
Specimen Label: GUDMAP:15290
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:3724922
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421573
Age: embryonic day 14.5
Image: MH1523; Specimen C1522
Note: Expression was weak in whisker follicle.
Specimen Label: MH1523; Specimen C1522
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691623
Age: postnatal adult
Image: JAX_1371689
Specimen Label: JAX_1371689
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:2654965
Assay Type: RNA in situ
Annotation Date: 2013-01-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5460832
Age: postnatal adult
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 10
Publication
First Author: Park YJ
Year: 2023
Journal: EMBO J
Title: MARCH5-dependent NLRP3 ubiquitination is required for mitochondrial NLRP3-NEK7 complex formation and NLRP3 inflammasome activation.
Volume: 42
Issue: 19
Pages: e113481
Publication  
First Author: Tang T
Year: 2021
Journal: Front Immunol
Title: The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3.
Volume: 12
Pages: 741839
Publication
First Author: Zheng S
Year: 2023
Journal: Mol Cell
Title: ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation.
Volume: 83
Issue: 24
Pages: 4570-4585.e7
Publication  
First Author: Ren GM
Year: 2021
Journal: Sci Immunol
Title: Pharmacological targeting of NLRP3 deubiquitination for treatment of NLRP3-associated inflammatory diseases.
Volume: 6
Issue: 58
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
Publication
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase Nek7
Type: chain
End: 302
UniProt Feature
Begin: 146
Description: Phosphoserine; by NEK7
Type: modified residue
End: 146
UniProt Feature
Begin: 134
Description: Phosphoserine; by NEK7
Type: modified residue
End: 134
Publication
First Author: Hughes MM
Year: 2019
Journal: Cell Rep
Title: Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Volume: 29
Issue: 1
Pages: 151-161.e5
UniProt Feature
Begin: 620
Description: Phosphothreonine; by NEK6 and NEK7
Type: modified residue
End: 620
Protein
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
UniProt Feature
Begin: 412
Description: Phosphothreonine; by MTOR, NEK6 and NEK7
Type: modified residue
End: 412
Pathway
Allele
Name: NIMA (never in mitosis gene a)-related expressed kinase 7; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: NIMA (never in mitosis gene a)-related expressed kinase 7; targeted mutation 2, Benny Motro
Allele Type: Targeted
Attribute String: Conditional ready
Publication
First Author: Belham C
Year: 2003
Journal: J Biol Chem
Title: A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases.
Volume: 278
Issue: 37
Pages: 34897-909
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 984  
Fragment?: false
Allele
Name: transgene insertion MN733, Nathaniel Heintz
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: transgenic, mutant stock
Allele
Name: NIMA (never in mitosis gene a)-related expressed kinase 7; targeted mutation 1, Benny Motro
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Nek7/Nek7
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * ICR
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nek7/Nek7
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 398  
Fragment?: false
Publication
First Author: Green JP
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming.
Volume: 115
Issue: 40
Pages: E9371-E9380
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: false
Publication
First Author: Yang XD
Year: 2020
Journal: EMBO J
Title: PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.
Volume: 39
Issue: 2
Pages: e102201