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Search results 301 to 400 out of 935 for Nf1

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Type Details Score
Publication
First Author: Dodd RD
Year: 2017
Journal: Cancer Res
Title: NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response.
Volume: 77
Issue: 16
Pages: 4486-4497
Publication
First Author: Chaney KE
Year: 2020
Journal: Cancer Res
Title: Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST.
Volume: 80
Issue: 21
Pages: 4720-4730
Publication
First Author: Deo M
Year: 2013
Journal: J Invest Dermatol
Title: Differential effects of neurofibromin gene dosage on melanocyte development.
Volume: 133
Issue: 1
Pages: 49-58
Publication
First Author: Reilly KM
Year: 2000
Journal: Nat Genet
Title: Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects.
Volume: 26
Issue: 1
Pages: 109-13
Publication
First Author: Galvao RP
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process.
Volume: 111
Issue: 40
Pages: E4214-23
Publication
First Author: Wang HF
Year: 2011
Journal: J Clin Invest
Title: Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.
Volume: 121
Issue: 12
Pages: 4820-37
Publication
First Author: Wong JC
Year: 2010
Journal: Blood
Title: Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.
Volume: 115
Issue: 22
Pages: 4524-32
Publication
First Author: Peacock JD
Year: 2018
Journal: Cancer Res
Title: Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
Volume: 78
Issue: 13
Pages: 3672-3687
Publication
First Author: Rhodes SD
Year: 2019
Journal: Hum Mol Genet
Title: Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation.
Volume: 28
Issue: 16
Pages: 2752-2762
Publication
First Author: Li H
Year: 2002
Journal: Cancer Res
Title: Epidermal growth factor receptor signaling pathways are associated with tumorigenesis in the Nf1:p53 mouse tumor model.
Volume: 62
Issue: 15
Pages: 4507-13
Publication  
First Author: Duan JH
Year: 2014
Journal: Neuroscience
Title: N-type calcium current, Cav2.2, is enhanced in small-diameter sensory neurons isolated from Nf1+/- mice.
Volume: 270
Pages: 192-202
Publication
First Author: Rhodes SD
Year: 2013
Journal: J Bone Miner Res
Title: Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model.
Volume: 28
Issue: 12
Pages: 2476-89
Publication
First Author: de la Croix Ndong J
Year: 2015
Journal: J Bone Miner Res
Title: Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx -/- mice.
Volume: 30
Issue: 1
Pages: 55-63
Publication
First Author: Lakkis MM
Year: 1998
Journal: Development
Title: Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart.
Volume: 125
Issue: 22
Pages: 4359-67
Publication
First Author: Schachter NF
Year: 2021
Journal: Nat Commun
Title: Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Volume: 12
Issue: 1
Pages: 5238
Publication
First Author: Lin L
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Mice lacking neurofibromin develop gastric hyperplasia.
Volume: 297
Issue: 4
Pages: G751-61
Publication
First Author: Lee DY
Year: 2012
Journal: Cancer Cell
Title: Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.
Volume: 22
Issue: 1
Pages: 131-8
Publication  
First Author: Yzaguirre AD
Year: 2015
Journal: Elife
Title: Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.
Volume: 4
Pages: e07780
Publication
First Author: Johannessen CM
Year: 2008
Journal: Curr Biol
Title: TORC1 is essential for NF1-associated malignancies.
Volume: 18
Issue: 1
Pages: 56-62
Publication
First Author: Malone CF
Year: 2014
Journal: Cancer Discov
Title: Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers.
Volume: 4
Issue: 9
Pages: 1062-73
Publication
First Author: Yang A
Year: 2011
Journal: Cancer Res
Title: Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.
Volume: 71
Issue: 10
Pages: 3573-81
Publication
First Author: Costa RM
Year: 2002
Journal: Nature
Title: Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Volume: 415
Issue: 6871
Pages: 526-30
Publication
First Author: Gregorian C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PTEN dosage is essential for neurofibroma development and malignant transformation.
Volume: 106
Issue: 46
Pages: 19479-84
Publication
First Author: Su W
Year: 2007
Journal: Glia
Title: Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
Volume: 55
Issue: 7
Pages: 723-33
Publication
First Author: Yang FC
Year: 2006
Journal: J Clin Invest
Title: Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
Volume: 116
Issue: 11
Pages: 2880-91
Publication  
First Author: Hodgdon KE
Year: 2012
Journal: Neuroscience
Title: Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.
Volume: 206
Pages: 237-44
Publication
First Author: Li F
Year: 2006
Journal: Hum Mol Genet
Title: Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells.
Volume: 15
Issue: 11
Pages: 1921-30
Publication
First Author: Yan J
Year: 2008
Journal: Hum Mol Genet
Title: Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1.
Volume: 17
Issue: 7
Pages: 936-48
Publication
First Author: Bessler WK
Year: 2016
Journal: Hum Mol Genet
Title: Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation.
Volume: 25
Issue: 6
Pages: 1129-39
Publication
First Author: Staser K
Year: 2013
Journal: J Clin Invest
Title: Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.
Volume: 123
Issue: 1
Pages: 329-34
Publication
First Author: Shollar D
Year: 2004
Journal: Oncogene
Title: JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors.
Volume: 23
Issue: 32
Pages: 5459-67
Publication
First Author: Ohka F
Year: 2019
Journal: Cancer Res
Title: Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas.
Volume: 79
Issue: 19
Pages: 4814-4827
Publication
First Author: Gonzalez PP
Year: 2018
Journal: Glia
Title: p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.
Volume: 66
Issue: 5
Pages: 999-1015
Publication
First Author: Silva AJ
Year: 1997
Journal: Nat Genet
Title: A mouse model for the learning and memory deficits associated with neurofibromatosis type I.
Volume: 15
Issue: 3
Pages: 281-4
Publication
First Author: Carbe C
Year: 2011
Journal: Hum Mol Genet
Title: Lens induction requires attenuation of ERK signaling by Nf1.
Volume: 20
Issue: 7
Pages: 1315-23
Publication    
First Author: Kim E
Year: 2014
Journal: Elife
Title: Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.
Volume: 3
Publication
First Author: Hegedus B
Year: 2007
Journal: Cell Stem Cell
Title: Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms.
Volume: 1
Issue: 4
Pages: 443-57
Publication
First Author: Lakkis MM
Year: 1999
Journal: Dev Biol
Title: Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects.
Volume: 212
Issue: 1
Pages: 80-92
Publication
First Author: Silvestre DC
Year: 2010
Journal: PLoS One
Title: Growth of peripheral and central nervous system tumors is supported by cytoplasmic c-Fos in humans and mice.
Volume: 5
Issue: 3
Pages: e9544
Publication
First Author: McDaniel AS
Year: 2008
Journal: Blood
Title: Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.
Volume: 112
Issue: 12
Pages: 4646-54
Publication  
First Author: Wang T
Year: 2015
Journal: Front Cell Neurosci
Title: In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.
Volume: 9
Pages: 234
Publication
First Author: Brown JA
Year: 2012
Journal: Mol Cell Neurosci
Title: Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner.
Volume: 49
Issue: 1
Pages: 13-22
Publication
First Author: Chen S
Year: 2010
Journal: Am J Pathol
Title: Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.
Volume: 177
Issue: 6
Pages: 3125-32
Publication
First Author: Kolanczyk M
Year: 2007
Journal: Hum Mol Genet
Title: Multiple roles for neurofibromin in skeletal development and growth.
Volume: 16
Issue: 8
Pages: 874-86
Publication
First Author: Kossler N
Year: 2011
Journal: Hum Mol Genet
Title: Neurofibromin (Nf1) is required for skeletal muscle development.
Volume: 20
Issue: 14
Pages: 2697-709
Publication
First Author: Nguyen HT
Year: 2017
Journal: Hum Mol Genet
Title: Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice.
Volume: 26
Issue: 19
Pages: 3797-3807
Publication
First Author: Ingram DA
Year: 2001
Journal: J Exp Med
Title: Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.
Volume: 194
Issue: 1
Pages: 57-69
Publication
First Author: Zhai Y
Year: 2017
Journal: J Pathol
Title: High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.
Volume: 243
Issue: 1
Pages: 16-25
Publication
First Author: Werner P
Year: 1997
Journal: Genomics
Title: Physical and linkage mapping of human chromosome 17 loci to dog chromosomes 9 and 5.
Volume: 42
Issue: 1
Pages: 74-82
Publication
First Author: Liu X
Year: 2020
Journal: Gastroenterology
Title: Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution.
Volume: 158
Issue: 6
Pages: 1728-1744.e14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Mantani A
Year: 1994
Journal: Gene
Title: A novel isoform of the neurofibromatosis type-1 mRNA and a switch of isoforms during murine cell differentiation and proliferation.
Volume: 148
Issue: 2
Pages: 245-51
Publication
First Author: Buchberg AM
Year: 1990
Journal: Nature
Title: Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway.
Volume: 347
Issue: 6290
Pages: 291-4
Publication
First Author: Chohan H
Year: 2018
Journal: PLoS One
Title: Neurofibromin haploinsufficiency results in altered spermatogenesis in a mouse model of neurofibromatosis type 1.
Volume: 13
Issue: 12
Pages: e0208835
Publication
First Author: Mo W
Year: 2013
Journal: Cell
Title: CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.
Volume: 152
Issue: 5
Pages: 1077-90
Publication
First Author: Devon RS
Year: 2001
Journal: Clin Genet
Title: Sixty-three bases of DNA affects learning ability: using mouse models to dissect the complex components of neurofibromatosis
Volume: 60
Issue: 2
Pages: 99-103
Publication
First Author: Sun T
Year: 2014
Journal: J Clin Invest
Title: Sexually dimorphic RB inactivation underlies mesenchymal glioblastoma prevalence in males.
Volume: 124
Issue: 9
Pages: 4123-33
Publication
First Author: Prada CE
Year: 2013
Journal: Acta Neuropathol
Title: Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition.
Volume: 125
Issue: 1
Pages: 159-68
Publication
First Author: Shen Z
Year: 2021
Journal: Cell Rep
Title: Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis.
Volume: 34
Issue: 11
Pages: 108853
Publication
First Author: Ono K
Year: 2013
Journal: Hum Mol Genet
Title: The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
Volume: 22
Issue: 15
Pages: 3048-62
Publication
First Author: Toonen JA
Year: 2017
Journal: Neuro Oncol
Title: Defining the temporal course of murine neurofibromatosis-1 optic gliomagenesis reveals a therapeutic window to attenuate retinal dysfunction.
Volume: 19
Issue: 6
Pages: 808-819
Publication
First Author: Pelle DW
Year: 2014
Journal: PLoS One
Title: Genetic and functional studies of the intervertebral disc: a novel murine intervertebral disc model.
Volume: 9
Issue: 12
Pages: e112454
Publication
First Author: Zhu Y
Year: 2001
Journal: Exp Cell Res
Title: Neurofibromin, a tumor suppressor in the nervous system.
Volume: 264
Issue: 1
Pages: 19-28
Publication
First Author: Schlake T
Year: 1999
Journal: Oncogene
Title: Predetermined chromosomal deletion encompassing the Nf-1 gene.
Volume: 18
Issue: 44
Pages: 6078-82
Publication
First Author: Julien JP
Year: 1985
Journal: Biochim Biophys Acta
Title: Cloning of a cDNA encoding the smallest neurofilament protein from the rat.
Volume: 825
Issue: 4
Pages: 398-404
Publication
First Author: Nehls M
Year: 1994
Journal: Oncogene
Title: Exon amplification from complete libraries of genomic DNA using a novel phage vector with automatic plasmid excision facility: application to the mouse neurofibromatosis-1 locus.
Volume: 9
Issue: 8
Pages: 2169-75
Publication
First Author: Riccardi VM
Year: 1994
Journal: Am J Pathol
Title: Neurofibromatosis and related tumors. Natural occurrence and animal models.
Volume: 145
Issue: 5
Pages: 994-1000
Publication
First Author: Santagata S
Year: 2013
Journal: Science
Title: Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state.
Volume: 341
Issue: 6143
Pages: 1238303
Publication
First Author: Chen YH
Year: 2015
Journal: Cell Rep
Title: Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties.
Volume: 10
Issue: 11
Pages: 1899-912
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204477
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204479
Age: postnatal week 6-8
Image: st96_178
Specimen Label: None
Detected: true
Specimen Num: 13